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Proteome Profiler Human Cytokine Array Kit
R&D Systems, Inc. a Bio-Techne Brand
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The Human Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates. The amount of cell culture supernate used on each array and the duration of exposure to X-ray film is indicated below. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. 1A: THP-1 human acute monocytic leukemia cells were untreated or treated with 1 µg/mL LPS for 4 hours, then 5mM Nigericin (Tocris, Catalog # 4312) for 1 hour (50 µL of cell culture supernate, 10 minute exposure). 1B: SW480 human colorectal adenocarcinoma cells were untreated or treated with 100 ng/mL LPS for 24 hours (500 µL of cell culture supernate, 10 minute exposure). |
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The Human Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell lysates. The amount of cell lysate used on each array and the duration of exposure to X-ray film is indicated below. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. 2A: SW1353 human chondrosarcoma cells were untreated or treated with 5 ng/mL recombinant human IL-1 alpha (R&D Systems, Catalog # 200-LA) and 10 ng/mL recombinant human OSM (R&D Systems, Catalog # 295-OM) for 24 hours (200 µg of cell lysate, 5 minute exposure). 2B: THP-1 human acute monocytic leukemia cells were untreated or treated with 1 µg/mL recombinant human IFN-gamma (R&D Systems, Catalog # 285-IF) for 8 hours, then 1 µg/mL LPS for 16 hours (200 µg of cell lysate, 5 minute exposure). |
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The Human Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in tissue lysate samples.
200 µg of tissue lysate was run on each array. Data shown are from a 5 minute exposure to X-ray film. |
Citations for Proteome Profiler Human Cytokine Array Kit (253)
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Citations are publications that use Bio-Techne products. Selected citations for Proteome Profiler Human Cytokine Array Kit include:
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Species: Human
Sample Types: Cell Culture Supernates
A Bugatti et al. (2023-01-01), The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells Viruses, 15(2).
PMID: 36851546 -
Species: Human
Sample Types: Cell Culture Supernates
V Sko?ková et al. (2023-01-01), Cyanobacterial Harmful Bloom Lipopolysaccharides Induce Pro-Inflammatory Effects in Immune and Intestinal Epithelial Cells In Vitro Toxins, 15(3).
PMID: 36977060 -
Species: Human
Sample Types: Cell Culture Supernates
P Bajwa et al. (2023-01-01), Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis JCI Insight, 0(0).
PMID: 36795484 -
Species: Human
Sample Types: Serum
MFS Souza et al. (2022-01-01), Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects Mediators of Inflammation, 2022(0):3977585.
PMID: 35075348 -
Species: Human
Sample Types: Cell Culture Supernates
SH Lin et al. (2022-01-01), TNF-alpha Activating Osteoclasts in Patients with Psoriatic Arthritis Enhances the Recruitment of Osteoclast Precursors: A Plausible Role of WNT5A-MCP-1 in Osteoclast Engagement in Psoriatic Arthritis International Journal of Molecular Sciences, 23(2).
PMID: 35055107 -
Species: Human
Sample Types: Cell Culture Supernates
RB Riddle et al. (2022-01-01), Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model Scientific Reports, 12(1):6855.
PMID: 35477984 -
Species: Human
Sample Types: Cell Culture Supernates
K Nakamura et al. (2022-01-01), Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation Scientific Reports, 12(1):5181.
PMID: 35410994 -
Species: Human
Sample Types: Cell Culture Supernates
S Okikawa et al. (2022-01-01), Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer Oncology reports, 47(4).
PMID: 35169858 -
Species: Human
Sample Types: Cell Culture Supernates
J Zinngrebe et al. (2022-01-01), Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS Embo Molecular Medicine, 0(0):e14901.
PMID: 35170849 -
Species: Human
Sample Types: Cell Culture Supernates
Z Li et al. (2022-01-01), ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation Nature Communications, 13(1):2011.
PMID: 35440136 -
Species: Human
Sample Types: Cell Culture Supernates
JP Gundlach et al. (2022-01-01), Paracrine Interaction of Cholangiocellular Carcinoma with Cancer-Associated Fibroblasts and Schwann Cells Impact Cell Migration Journal of Clinical Medicine, 11(10).
PMID: 35628911 -
Species: Human
Sample Types: Cell Culture Supernates
S Morin et al. (2022-01-01), Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model Cells, 11(9).
PMID: 35563819 -
Species: Human
Sample Types: Cell Culture Supernates
KW Lee et al. (2022-01-01), PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression Nature Communications, 13(1):2793.
PMID: 35589735 -
Species: Human
Sample Types: Cell Culture Supernates
Y Tian et al. (2022-01-01), Exosomal B7-H4 from irradiated glioblastoma cells contributes to increase FoxP3 expression of differentiating Th1 cells and promotes tumor growth Redox Biology, 56(0):102454.
PMID: 36044789 -
Species: Human
Sample Types: Cell Culture Supernates
NM Dräger et al. (2022-01-01), A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states Nature Neuroscience, 0(0).
PMID: 35953545 -
Species: Human
Sample Types: Cell Culture Supernates
L Garcia-Ger et al. (2022-01-01), MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment BMC Cancer, 22(1):669.
PMID: 35715791 -
Species: Human
Sample Types: Cell Culture Supernates
D Regev et al. (2022-01-01), Obstructive Sleep Apnea Syndrome In Vitro Model: Controlled Intermittent Hypoxia Stimulation of Human Stem Cells-Derived Cardiomyocytes International Journal of Molecular Sciences, 23(18).
PMID: 36142186 -
Species: Human
Sample Types: Cell Culture Supernates
A Domínguez- et al. (2022-01-01), Cytokine profile of human limbal myofibroblasts: Key players in corneal antiviral response Cytokine, 160(0):156047.
PMID: 36183616 -
Species: Human
Sample Types: Cell Culture Supernates
A Emam et al. (2022-01-01), Stalled replication fork protection limits cGAS-STING and P-body-dependent innate immune signalling Nature Cell Biology, 24(7):1154-1164.
PMID: 35817959 -
Species: Human
Sample Types: Cell Culture Supernates
P Chen et al. (2022-01-01), Non-small cell lung cancer-derived exosomes promote proliferation, phagocytosis, and secretion of microglia via exosomal microRNA in the metastatic microenvironment Translational Oncology, 27(0):101594.
PMID: 36463825 -
Species: Human
Sample Types: Plasma
C Villarroya et al. (2022-01-01), Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility Science Advances, 8(44):eabq5914.
PMID: 36322655 -
Species: Human
Sample Types: Cell Culture Supernates
X Chen et al. (2022-01-01), Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis Journal of Translational Medicine, 20(1):322.
PMID: 35864535 -
Species: Human
Sample Types: Cell Culture Supernates
YK Stepanov et al. (2022-01-01), Profound Effects of Dexamethasone on the Immunological State, Synthesis and Secretion Capacity of Human Testicular Peritubular Cells Cells, 11(19).
PMID: 36231125 -
Species: Human
Sample Types: Cell Culture Supernates
M Rovira et al. (2022-01-01), The lysosomal proteome of senescent cells contributes to the senescence secretome Aging Cell, 0(0):e13707.
PMID: 36087066 -
Species: Mouse
Sample Types: Tissue Homogenates
WN Liu et al. (2022-01-01), Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model Science Advances, 8(47):eadd1187.
PMID: 36417514 -
Species: Human
Sample Types: Cell Culture Supernates
Z Wang et al. (2022-01-01), Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion Nature Communications, 13(1):6308.
PMID: 36274066 -
Species: Human
Sample Types: Cell Culture Supernates
F Caso et al. (2022-01-01), Analysis of rheumatoid- vs psoriatic arthritis synovial fluid reveals differential macrophage (CCR2) and T helper subsets (STAT3/4 and FOXP3) activation Autoimmunity reviews, 21(12):103207.
PMID: 36191778 -
Species: Human
Sample Types: Cell Culture Supernates
A Piunti et al. (2022-01-01), Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma Science Advances, 8(40):eabo8043.
PMID: 36197969 -
Species: Human
Sample Types: Cell Culture Supernates
SH Hong et al. (2022-01-01), EGFR-Tyrosine Kinase Inhibitors Induced Activation of the Autocrine CXCL10/CXCR3 Pathway through Crosstalk between the Tumor and the Microenvironment in EGFR-Mutant Lung Cancer Cancers, 15(1).
PMID: 36612121 -
Species: Human
Sample Types: Cell Culture Supernates
Y Yuhas et al. (2022-01-01), Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells Brain sciences, 12(12).
PMID: 36552163 -
Species: Human
Sample Types: Cell Culture Supernates
O Benchama et al. (2022-01-01), Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA) Scientific Reports, 12(1):22255.
PMID: 36564457 -
Species: Human
Sample Types: Cell Culture Supernates
K Tokuda et al. (2021-01-01), The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma Oncotarget, 12(4):333-343.
PMID: 33659044 -
Species: Human
Sample Types: Cell Culture Supernates
T Takemoto et al. (2021-01-01), Acid-electrolyzed functional water-induces Interleukin-1&alpha release from Intracellular Storage Sites in Oral Squamous Cell Carcinoma International Journal of Medical Sciences, 18(8):1746-1752.
PMID: 33746591 -
Species: Human
Sample Types: Cell Culture Supernates
E Yeini et al. (2021-01-01), P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression Nature Communications, 12(1):1912.
PMID: 33771989 -
PE Squires et al. (2021-01-01), Danegaptide Prevents TGF&beta1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney International Journal of Molecular Sciences, 22(6).
PMID: 33802083 -
Species: Human
Sample Types: Cell Lysates
AK Menzner et al. (2021-01-01), Hydrogen-Peroxide Synthesis and LDL-Uptake Controls Immunosuppressive Properties in Monocyte-Derived Dendritic Cells Cancers, 13(3).
PMID: 33530408 -
Species: Human
Sample Types: Cell Culture Supernates
YP Yang et al. (2021-01-01), Musashi-1 Regulates MIF1-Mediated M2 Macrophage Polarization in Promoting Glioblastoma Progression Cancers, 13(8).
PMID: 33918794 -
Species: Human
Sample Types: Cell Culture Supernates
D You et al. (2021-01-01), Celastrol attenuates the inflammatory response by inhibiting IL?1&beta expression in triple?negative breast cancer cells Oncology reports, 45(6).
PMID: 33846813 -
Species: Human
Sample Types: Serum
F Hempel et al. (2021-01-01), Caspase-Cleaved Keratin 18 Measurements Identified Ongoing Liver Injury after Bariatric Surgery Journal of Clinical Medicine, 10(6).
PMID: 33809676 -
Species: Human
Sample Types: Cell Culture Supernates
S Ghosh et al. (2021-01-01), PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR Cell Reports, 35(8):109181.
PMID: 34038737 -
Species: Human
Sample Types: Cell Culture Supernates
G Miglietta et al. (2021-01-01), G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells Nucleic Acids Research, 0(0).
PMID: 34139015 -
Species: Human
Sample Types: Cell Culture Supernates
J Wang et al. (2021-01-01), Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells Oncogenesis, 10(1):8.
PMID: 33431808 -
Species: Human
Sample Types: Cell Culture Supernates
A Vaughan-Ja et al. (2021-01-01), Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium Stem Cell Reports, 0(0).
PMID: 34171284 -
Species: Human
Sample Types: Cell Culture Supernates
J Rostami et al. (2021-01-01), Crosstalk between astrocytes and microglia results in increased degradation of &alpha-synuclein and amyloid-&beta aggregates Journal of Neuroinflammation, 18(1):124.
PMID: 34082772 -
Species: Human
Sample Types: Cell Culture Supernates
CS Thomson et al. (2021-01-01), WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth Oncogene, 40(24):4229-4241.
PMID: 34079083 -
Species: Human
Sample Types: Cell Culture Super
CC Clement et al. (2021-01-01), 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine Nature Communications, 12(1):4447.
PMID: 34290243 -
Species: Human
Sample Types: Cell Culture Supernates
Z Yang et al. (2021-01-01), USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade Nature Communications, 12(1):4852.
PMID: 34381028 -
Species: Human
Sample Types: Cell Culture Supernates
F Caccuri et al. (2021-01-01), SARS-CoV-2 Infection Remodels the Phenotype and Promotes Angiogenesis of Primary Human Lung Endothelial Cells Microorganisms, 9(7).
PMID: 34361874 -
Species: Human
Sample Types: Cell Culture Supernates
A Armento et al. (2021-01-01), CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-kappaB Pathway International Journal of Molecular Sciences, 22(16).
PMID: 34445430 -
Species: Human
Sample Types: Cell Culture Supernates
AHA Al-Rikabi et al. (2021-01-01), Dermal fibroblasts cultured from donors with type 2 diabetes mellitus retain an epigenetic memory associated with poor wound healing responses Scientific Reports, 11(1):1474.
PMID: 33446687 -
Species: Human
Sample Types: Cell Culture Supernates
J Chen et al. (2021-01-01), Chromium Oxide Nanoparticle Impaired Osteogenesis and Cellular Response to Mechanical Stimulus International Journal of Nanomedicine, 16(0):6157-6170.
PMID: 34511912 -
Species: Human
Sample Types: Cell Culture Supernates
JH Kwon et al. (2021-01-01), Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling Cells, 10(1).
PMID: 33401590 -
Species: Human
Sample Types: Cell Culture Supernates
F He et al. (2021-01-01), Analysis of the Influence of Jaw Periosteal Cells on Macrophages Phenotype Using an Innovative Horizontal Coculture System Biomedicines, 9(12).
PMID: 34944569 -
Species: Human
Sample Types: Cell Culture Supernates
F Bohländer et al. (2021-01-01), The Functional Role of IgA in the IgM/IgA-Enriched Immunoglobulin Preparation Trimodulin Biomedicines, 9(12).
PMID: 34944644 -
Species: Human
Sample Types: Cell Lysates
DK Shishkova et al. (2021-01-01), Calciprotein Particles Link Disturbed Mineral Homeostasis with Cardiovascular Disease by Causing Endothelial Dysfunction and Vascular Inflammation International Journal of Molecular Sciences, 22(22).
PMID: 34830334 -
Species: Human
Sample Types: Whole Cells
Y Liu et al. (2021-01-01), A Fbxo48 inhibitor prevents pAMPK&alpha degradation and ameliorates insulin resistance Nature Chemical Biology, 0(0).
PMID: 33495648 -
Species: Human
Sample Types: Cell Culture Supernates
S Ma et al. (2021-01-01), Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype Cell Reports, 34(6):108726.
PMID: 33567287 -
Species: Human
Sample Types: Cell Lysates
J Kim et al. (2020-01-01), STAT3 Relays a Differential Response to Melanoma-Associated NRAS Mutations Cancers (Basel), 12(1).
PMID: 31906480 -
Species: Human
Sample Types: Cell Lysates
I Arias de l et al. (2020-01-01), Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies Haematologica, 0(0).
PMID: 31949015 -
Species: Human
Sample Types: Cell Culture Supernates
F Pelon et al. (2020-01-01), Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms Nat Commun, 11(1):404.
PMID: 31964880 -
Species: Human
Sample Types: Cell Culture Supernates
PM Witschen et al. (2020-01-01), Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer Cancers (Basel), 12(5).
PMID: 32455980 -
Species: Human
Sample Types: Cell Culture Supernates
KT Chan et al. (2020-01-01), A functional genetic screen defines the AKT-induced senescence signaling network Cell Death Differ., 27(2):725-741.
PMID: 31285545 -
Species: Human
Sample Types: Cell Culture Supernates
M Minopoli et al. (2020-01-01), Inhibiting Monocyte Recruitment to Prevent the Pro-Tumoral Activity of Tumor-Associated Macrophages in Chondrosarcoma Cells, 9(4).
PMID: 32344648 -
Species: Human
Sample Types: Cell Culture Supernates
S Kim et al. (2020-01-01), WNT5A augments cell invasiveness by inducing CXCL8 in HER2-positive breast cancer cells Cytokine, 135(0):155213.
PMID: 32736336 -
Species: Human
Sample Types: Cell Culture Supernates
ML Coluccio et al. (2020-01-01), Microenvironment Molecular Profile Combining Glycation Adducts and Cytokines Patterns on Secretome of Short-term Blood-derived Cultures during Tumour Progression Int J Mol Sci, 21(13).
PMID: 32630302 -
Species: Human
Sample Types: Cell Culture Supernates
A Müller et al. (2020-01-01), The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis J. Clin. Invest., 0(0).
PMID: 32701505 -
Species: Human
Sample Types: Cell Culture Supernates
S Valle et al. (2020-01-01), Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells Nat Commun, 11(1):5265.
PMID: 33067432 -
Species: Human
Sample Types: Cell Culture Supernates
B Oulès et al. (2020-01-01), Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis Nat Commun, 11(1):5067.
PMID: 33082341 -
Species: Human
Sample Types: Cell Culture Supernates
A Ianevski et al. (2020-01-01), Identification and Tracking of Antiviral Drug Combinations Viruses, 12(10).
PMID: 33080984 -
Species: Human
Sample Types: Cell Culture Supernates
S Mignot et al. (2020-01-01), Unique inflammatory signature in haemophilic arthropathy: miRNA changes due to interaction between blood and fibroblast-like synoviocytes J Cell Mol Med, 0(0).
PMID: 33159500 -
Species: Human
Sample Types: Cell Lysates
HS Lee et al. (2020-01-01), Rhus verniciflua Stokes extract suppresses migration and invasion in human gastric adenocarcinoma AGS cells Nutr Res Pract, 14(5):463-477.
PMID: 33029287 -
Species: Human
Sample Types: Cell Lysates
J Domenech et al. (2020-01-01), Interactions of graphene oxide and graphene nanoplatelets with the in vitro Caco-2/HT29 model of intestinal barrier Sci Rep, 10(1):2793.
PMID: 32066787 -
Species: Human
Sample Types: Cell Culture Supernates
MA Rahman et al. (2020-01-01), Mucosal-associated invariant T (MAIT) cells provide B-cell help in vaccinated and subsequently SIV-infected Rhesus Macaques Sci Rep, 10(1):10060.
PMID: 32572140 -
Species: Human
Sample Types: Cell Culture Supernates
EN Arwert et al. (2020-01-01), STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy Nat. Cell Biol., 0(0).
PMID: 32483388 -
Species: Human
Sample Types: Cell Culture Supernates
M Matysiak-K et al. (2020-01-01), Two Sides to the Same Coin-Cytotoxicity vs. Potential Metastatic Activity of AgNPs Relative to Triple-Negative Human Breast Cancer MDA-MB-436 Cells Molecules, 25(10).
PMID: 32443890 -
Species: Human
Sample Types: Cell Culture Supernates
Y Wada et al. (2020-01-01), The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment Oncotarget, 11(49):4593-4604.
PMID: 33346211 -
Species: Mouse
Sample Types: Cell Lysates
IM Sayed et al. (2020-01-01), The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells Cells, 9(9).
PMID: 32872214 -
Species: Human
Sample Types: Cell Lysates
GE Lim et al. (2020-01-01), Pygenic Acid A (PA) Sensitizes Metastatic Breast Cancer Cells to Anoikis and Inhibits Metastasis In Vivo Int J Mol Sci, 21(22).
PMID: 33182770 -
Species: Human
Sample Types: Cell Cultur Supernates
JY Kim et al. (2020-01-01), Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves' ophthalmopathy Stem Cell Res Ther, 11(1):469.
PMID: 33153489 -
Species: Human
Sample Types: Cell Culture Supernates
A Anloague et al. (2020-01-01), Mechanical stimulation of human dermal fibroblasts regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies BMC Res Notes, 13(1):400.
PMID: 32854782 -
Species: Porcine
Sample Types: Plasma
R Ramirez-Ca et al. (2020-01-01), Targeting TLR4 with ApTOLL Improves Heart Function in Response to Coronary Ischemia Reperfusion in Pigs Undergoing Acute Myocardial Infarction Biomolecules, 10(8).
PMID: 32784904 -
Species: Human
Sample Types: Cell Culture Supernates
M Vijayan et al. (2020-01-01), Decidual glycodelin-A polarizes human monocytes towards a decidual macrophage-like phenotype via siglec-7 J. Cell. Sci., 0(0).
PMID: 32513821 -
Species: Human
Sample Types: Cell Culture Supernates
J Zhu et al. (2019-01-01), 1?,25(OH)2D3 attenuates IL-6 and IL-1?-mediated inflammatory responses in macrophage conditioned medium-stimulated human white preadipocytes by modulating p44/42 MAPK and NF-?B signaling pathways Diabetol Metab Syndr, 11(0):9.
PMID: 30697360 -
Species: Human
Sample Types: Serum
Y Ye et al. (2019-01-01), Anti ?-enolase antibody is a novel autoimmune biomarker for unexplained recurrent miscarriages EBioMedicine, 0(0).
PMID: 30827932 -
Species: Human
Sample Types: Cell Culture Supernates
J Nehls et al. (2019-01-01), Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner Cell Rep, 26(7):1841-1853.e6.
PMID: 30759394 -
Species: Xenograft
Sample Types: Cell Culture Supernates
I Kurelac et al. (2019-01-01), Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses Nat Commun, 10(1):903.
PMID: 30796225 -
Species: Human
Sample Types: Cell Culture Supernates
A Gartung et al. (2019-01-01), Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor Proc. Natl. Acad. Sci. U.S.A., 116(5):1698-1703.
PMID: 30647111 -
Species: Human
Sample Types: Serum
NY Maeda et al. (2019-01-01), Relation of Macrophage Migration Inhibitory Factor to Pulmonary Hemodynamics and Vascular Structure and Carbamyl-Phosphate Synthetase I Genetic Variations in Pediatric Patients with Congenital Cardiac Shunts Mediators Inflamm., 2019(0):7305028.
PMID: 30881226 -
Species: Human
Sample Types: Cell Culture Supernates
MC Wu et al. (2019-01-01), KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis Cell Death Dis, 10(2):68.
PMID: 30683841 -
Species: Human
Sample Types: Cell Culture Supernates
S Llanos et al. (2019-01-01), Lysosomal trapping of palbociclib and its functional implications Oncogene, 0(0).
PMID: 30692638 -
Species: Human
Sample Types: Cell Culture Supernates
V Verma et al. (2019-01-01), Loss of zinc-finger protein 143 contributes to tumour progression by interleukin-8-CXCR axis in colon cancer J. Cell. Mol. Med., 0(0).
PMID: 30933430 -
Species: Human
Sample Types: Cell Culture Supernates
MA Eckert et al. (2019-01-01), Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts Nature, 0(0).
PMID: 31043742 -
Species: Human
Sample Types: Cell Culture Supernates
PG Jobin et al. (2019-01-01), Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase J. Biol. Chem., 0(0).
PMID: 31324718 -
Species: Human
Sample Types: cell culture supernatant
M Dall et al. (2019-01-01), Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity J. Biol. Chem., 0(0).
PMID: 31320478 -
Species: Human
Sample Types: Cell Culture Supernates
S Pal-Ghosh et al. (2019-01-01), Transient Mitomycin C-treatment of human corneal epithelial cells and fibroblasts alters cell migration, cytokine secretion, and matrix accumulation Sci Rep, 9(1):13905.
PMID: 31554858 -
Species: Primate - Macaca fascicularis (Cynomolgus Macaque)
Sample Types: Tissue Homogenates
JH Kam et al. (2019-01-01), Fundamental differences in patterns of retinal ageing between primates and mice Sci Rep, 9(1):12574.
PMID: 31467395 -
Species: Human
Sample Types: Whole Cells
H Kim et al. (2019-01-01), Therapeutic effect of mesenchymal stem cells derived from human umbilical cord in rabbit temporomandibular joint model of osteoarthritis Sci Rep, 9(1):13854.
PMID: 31554894 -
Species: Human
Sample Types: Cell Culture Supernates
CA Valenzuela et al. (2019-01-01), SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells Int J Mol Sci, 20(21).
PMID: 31653055 -
Species: Human
Sample Types: Cell Culture Supernates
H Maekawa et al. (2019-01-01), Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury Cell Rep, 29(5):1261-1273.e6.
PMID: 31665638 -
Species: Human
Sample Types: Cell Lysates
P Luan et al. (2019-01-01), NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARgamma Nat Commun, 10(1):2882.
PMID: 31253783 -
Species: Human
Sample Types: Cell Culture Supernates
KE Lee et al. (2019-01-01), The efficacy of conditioned medium released by tonsil-derived mesenchymal stem cells in a chronic murine colitis model PLoS ONE, 14(12):e0225739.
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I Kurelac et al. (2019-01-01), A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma J Clin Med, 8(12).
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LM Ashander et al. (2019-01-01), Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells Invest. Ophthalmol. Vis. Sci., 60(14):4652-4660.
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E Ko et al. (2019-01-01), Ginsenoside Rh2 Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing NF-kappaB-Mediated Thymic Stromal Lymphopoietin Expression and T Helper Type 2 Differentiation Int J Mol Sci, 20(24).
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R Riise et al. (2019-01-01), Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes Sci Rep, 9(1):20407.
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KJ Pahk et al. (2019-01-01), Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers Sci Rep, 9(1):9050.
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M Ma et al. (2019-01-01), Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16 J. Immunol., 0(0).
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J Park et al. (2018-01-01), A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer's disease Nat. Neurosci., 21(7):941-951.
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JM Ubellacker et al. (2018-01-01), Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer Cancer Res., 0(0).
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SA Greenall et al. (2018-01-01), Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3 Transl Oncol, 11(4):971-978.
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Sample Types: Plasma
YC Liu et al. (2018-01-01), Cytokine MIF Enhances Blood-Brain Barrier Permeability: Impact for Therapy in Ischemic Stroke Sci Rep, 8(1):743.
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A Arta et al. (2018-01-01), Endothelial Protein C-Targeting Liposomes Show Enhanced Uptake and Improved Therapeutic Efficacy in Human Retinal Endothelial Cells Invest. Ophthalmol. Vis. Sci., 59(5):2119-2132.
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JA Fraser et al. (2018-01-01), Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations Sci Rep, 8(1):7506.
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W Dong et al. (2018-01-01), Overexpression of Rab11-FIP2 in colorectal cancer cells promotes tumor migration and angiogenesis through increasing secretion of PAI-1 Cancer Cell Int., 18(0):35.
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ÁF Kovács et al. (2018-01-01), The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells Sci Rep, 8(1):5426.
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S di Martino et al. (2018-01-01), HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome Oncogene, 0(0).
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KY Tang et al. (2018-01-01), Safety, pharmacokinetics, and biomarkers of F-652, a recombinant human interleukin-22 dimer, in healthy subjects Cell. Mol. Immunol., 0(0).
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DJ McGrail et al. (2018-01-01), Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers Nat Commun, 9(1):1317.
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S Srinivasan et al. (2018-01-01), Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer Cancer Res., 0(0).
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Y Wang et al. (2018-01-01), IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells JCI Insight, 3(23).
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K Lategan et al. (2018-01-01), Effects of Graphene Oxide Nanoparticles on the Immune System Biomarkers Produced by RAW 264.7 and Human Whole Blood Cell Cultures Nanomaterials (Basel), 8(2).
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A Rutkowska et al. (2018-01-01), EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes Neuropharmacology, 133(0):121-128.
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US Rao et al. (2017-01-01), Surface-bound galectin-4 regulates gene transcription and secretion of chemokines in human colorectal cancer cell lines Tumour Biol, 39(3):1010428317691.
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EJ Lim et al. (2017-01-01), Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells Oncotarget, 8(1):1438-1448.
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HB Song et al. (2017-01-01), Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling PLoS ONE, 12(4):e0175159.
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L Qiang et al. (2017-01-01), Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Autophagy, 0(0):0.
PMID: 28933598 -
Species: Human
Sample Types: Cell Culture Supernates
A Gabrielyan et al. (2017-01-01), Metabolically conditioned media derived from bone marrow stromal cells or human skin fibroblasts act as effective chemoattractants for mesenchymal stem cells Stem Cell Res Ther, 8(1):212.
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Species: Human
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L Borriello et al. (2017-01-01), Cancer-Associated Fibroblasts Share Characteristics and Pro-tumorigenic Activity with Mesenchymal Stromal Cells Cancer Res., 0(0).
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Y Wang et al. (2017-01-01), Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis Stem Cells, 0(0).
PMID: 28514506 -
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Q Wu et al. (2017-01-01), NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy Cell Death Differ., 0(0).
PMID: 28574504 -
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A Bott et al. (2017-01-01), miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A Oncotarget, 8(27):43897-43914.
PMID: 28159925 -
Species: Human
Sample Types: Amniotic Fluid
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WL Yeh et al. (2017-01-01), Peri-foci adipose-derived stem cells promote chemoresistance in breast cancer Stem Cell Res Ther, 8(1):177.
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Species: Human
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S Santaguida et al. (2017-01-01), Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System Dev. Cell, 41(6):638-651.e5.
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S Gomez-Chou et al. (2017-01-01), Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment Cancer Res, 0(0).
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A Hongo et al. (2017-01-01), The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells Invest. Ophthalmol. Vis. Sci., 58(9):3325-3334.
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Species: Human
Sample Types: Serum
RA Oliveira et al. (2017-01-01), Serum cytokine/chemokine profiles in patients with dengue fever (DF) and dengue hemorrhagic fever (FHD) by using protein array J. Clin. Virol, 89(0):39-45.
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T Hartwig et al. (2017-01-01), The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2 Mol. Cell, 65(4):730-742.e5.
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HE Wajdner et al. (2017-01-01), Orai and TRPC channel characterization in Fc?RI-mediated calcium signaling and mediator secretion in human mast cells Physiol Rep, 5(5).
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CA Nold-Petry et al. (2017-01-01), Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation Front Immunol, 8(0):1531.
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(2016-01-01), Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists Sci Rep, 6(0):34145.
PMID: 27667443 -
Species: Mouse
Sample Types: Plasma
Morton J et al. (2016-01-01), XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene, 35(3):290-300.
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AR Öze? et al. (2016-01-01), NF-?B-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer Oncogene, 0(0).
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C Guillou et al. (2016-01-01), Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function Sci Rep, 6(0):23796.
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Paul Digard (2016-01-01), Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity J. Virol., 90(20):9263-84.
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Skolekova S et al. (2016-01-01), Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells. Cell Commun Signal, 14(1):4.
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ME Legrier et al. (2016-01-01), Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer Br. J. Cancer, 114(2):177-87.
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(2016-01-01), The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma Cell Signal, 28(10):1555-1562.
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(2016-01-01), MicroRNAs regulate cytokine responses in gingival epithelial cells Infect Immun, 0(0).
PMID: 27600506 -
Species: Human
Sample Types: Serum
(2016-01-01), Serum Cytokines in Young Pediatric Patients with Congenital Cardiac Shunts and Altered Pulmonary Hemodynamics Mediators Inflamm, 2016(0):7672048.
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Matthew N Svalina (2016-01-01), IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma Sci Rep, 6(0):27012.
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(2016-01-01), The oncometabolite R-2-hydroxyglutarate activates NF-?B-dependent tumor-promoting stromal niche for acute myeloid leukemia cells Sci Rep, 6(0):32428.
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(2016-01-01), MEK and TAK1 regulate apoptosis in colon cancer cells with KRAS-dependent activation of proinflammatory signaling Mol Cancer Res, 0(0).
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J Gaston et al. (2016-01-01), Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents Oncotarget, 7(47):77205-77224.
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(2016-01-01), Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism Proc Natl Acad Sci USA, 0(0).
PMID: 27663735 -
Species: Human
Sample Types: Serum
Stavros Giaglis (2016-01-01), Multimodal Regulation of NET Formation in Pregnancy: Progesterone Antagonizes the Pro-NETotic Effect of Estrogen and G-CSF Front Immunol, 7(0):565.
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Resheq Y et al. (2015-01-01), Contact-dependent depletion of hydrogen peroxide by catalase is a novel mechanism of myeloid-derived suppressor cell induction operating in human hepatic stellate cells. J Immunol, 194(6):2578-86.
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Sample Types: Whole Cells
Liu M et al. (2015-01-01), New aspects of RpoE in uropathogenic Proteus mirabilis. Infect Immun, 83(3):966-77.
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Abraham M et al. (2015-01-01), In vitro Study of a Novel Stent Coating Using Modified CD39 Messenger RNA to Potentially Reduce Stent Angioplasty-Associated Complications. PLoS ONE, 10(9):e0138375.
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Zemskova M et al. (2015-01-01), Regulation of prostate stromal fibroblasts by the PIM1 protein kinase. Cell Signal, 27(1):135-46.
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Ignatz-Hoover et al. (2015-01-01), The role of TLR8 signaling in acute myeloid leukemia differentiation. Leukemia, 29(4):918-26.
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Lessard J et al. (2015-01-01), Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling. PLoS ONE, 10(3):e0122065.
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Paggetti J et al. (2015-01-01), Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts. Blood, 126(9):1106-17.
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Hashimoto M et al. (2015-01-01), Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1. J Immunol, 195(9):4341-50.
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Altara R et al. (2015-01-01), Diurnal rhythms of serum and plasma cytokine profiles in healthy elderly individuals assessed using membrane based multiplexed immunoassay. J Transl Med, 13(0):129.
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Mahon K et al. (2015-01-01), Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer. Br J Cancer, 112(8):1340-8.
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Kota et al. (2014-01-01), Differential MSC activation leads to distinct mononuclear leukocyte binding mechanisms. Sci Rep, 4(0):4565.
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Altara et al. (2014-01-01), Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample. BMC Biotechnol, 14(0):63.
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Xie et al. (2014-01-01), Moraxella catarrhalis adhesin UspA1-derived recombinant fragment rD-7 induces monocyte differentiation to CD14+CD206+ phenotype. PLoS ONE, 9(3):e90999.
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Choi S et al. (2014-01-01), Human astrocytes: secretome profiles of cytokines and chemokines. PLoS ONE, 9(4):e92325.
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Zhao H et al. (2014-01-01), Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia. J Immunol, 192(1):385-93.
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Yoon D et al. (2014-01-01), Interleukin-6 induces the lineage commitment of bone marrow-derived mesenchymal multipotent cells through down-regulation of Sox2 by osteogenic transcription factors. FASEB J, 28(7):3273-86.
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Frazier T et al. (2014-01-01), Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions. Stem Cells Dev, 23(9):968-77.
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Veldwijk M et al. (2014-01-01), The biological effect of large single doses: a possible role for non-targeted effects in cell inactivation. PLoS ONE, 9(1):e84991.
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Wang M et al. (2014-01-01), The RNA chaperone Hfq is involved in stress tolerance and virulence in uropathogenic Proteus mirabilis. PLoS ONE, 9(1):e85626.
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Bid et al. (2014-01-01), DeltaNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis. Cancer Res, 74(1):320-9.
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Marti H et al. (2014-01-01), Water-filtered infrared a irradiation in combination with visible light inhibits acute chlamydial infection. PLoS ONE, 9(7):e102239.
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Carrillo-Salinas F et al. (2014-01-01), A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis. PLoS ONE, 9(4):e94733.
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Kumar D et al. (2014-01-01), Decidual GM-CSF is a critical common intermediate necessary for thrombin and TNF induced in-vitro fetal membrane weakening. Placenta, 35(12):1049-56.
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Hongsrichan N et al. (2014-01-01), Cytokine/chemokine secretion and proteomic identification of upregulated annexin A1 from peripheral blood mononuclear cells cocultured with the liver fluke Opisthorchis viverrini. Infect Immun, 82(5):2135-47.
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Kakkola L et al. (2013-01-01), Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice. Cell Death Dis, 4(0):e742.
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Bid H et al. (2013-01-01), Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma. Clin Cancer Res, 19(24):6716-29.
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Arndt S et al. (2013-01-01), Cold atmospheric plasma (CAP) changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo. PLoS ONE, 8(11):e79325.
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Chaturvedi et al. (2013-01-01), Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest, 123(1):189-205.
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Kim Y et al. (2013-01-01), miR-200b and cancer/testis antigen CAGE form a feedback loop to regulate the invasion and tumorigenic and angiogenic responses of a cancer cell line to microtubule-targeting drugs. J Biol Chem, 288(51):36502-18.
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Civini S et al. (2013-01-01), Leukemia cells induce changes in human bone marrow stromal cells. J Transl Med, 11(0):298.
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Chen C et al. (2013-01-01), Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin Cancer Res, 19(7):1693-704.
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(2012-01-01), Differential interaction of the two related fungal species Candida albicans and Candida dubliniensis with human neutrophils. J. Immunol., 189(5):2502-11.
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(2012-01-01), A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappaB signaling and improves survival in mouse models of sepsis. Acta Pharmacol. Sin., 33(9):1204-16.
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Churchman SM et al. (2012-01-01), Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor. Clin. Exp. Rheumatol., 30(4):534-42.
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Sceneay J et al. (2012-01-01), Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. Cancer Res, 72(16):3906-11.
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Li J et al. (2012-01-01), Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients. J Biol Chem, 287(42):35484-95.
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Lohse S et al. (2012-01-01), Characterization of a Mutated IgA2 Antibody of the m(1) Allotype against the Epidermal Growth Factor Receptor for the Recruitment of Monocytes and Macrophages. J. Biol. Chem., 287(30):25139-50.
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Houser KR et al. (2012-01-01), Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond), 9(0):6.
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Ghislin S et al. (2012-01-01), LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro. BMC Cancer, 12(0):455.
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Denisova et al. (2012-01-01), Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection. J Biol Chem, 287(42):35324-32.
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Chihara T et al. (2012-01-01), HIV-1 proteins preferentially activate anti-inflammatory M2-type macrophages. J. Immunol., 188(8):3620-7.
PMID: 22407921 -
Species: Human
Sample Types: Cell Culture Supernates
Iram N et al. (2012-01-01), Age-related changes in expression and function of Toll-like receptors in human skin. Development, 139(22):4210-9.
PMID: 23034637 -
Species: Human
Sample Types: Cell Culture Supernates
Suzuki T et al. (2012-01-01), Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts. PLoS ONE, 7(3):e33474.
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Species: Human
Sample Types: Cell Culture Supernates
Southcombe J et al. (2011-01-01), The immunomodulatory role of syncytiotrophoblast microvesicles. PLoS ONE, 6(5):e20245.
PMID: 21633494 -
Species: Human
Sample Types: Serum
Aronis KN et al. (2011-01-01), Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans. Diabetologia, 54(9):2358-67.
PMID: 21660636 -
Species: Primate
Sample Types: Plasma
Frias AE et al. (2011-01-01), Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a nonhuman primate model of excess nutrition. Endocrinology, 152(6):2456-64.
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Species: Human
Sample Types: Cell Culture Supernates
Guery L et al. (2011-01-01), Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood, 118(17):4694-704.
PMID: 21876121 -
Species: Human
Sample Types: Cell Culture Supernates
Chang SK et al. (2011-01-01), Cadherin-11 regulates fibroblast inflammation. Proc. Natl. Acad. Sci. U.S.A., 108(20):8402-7.
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Species: Human
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Marcondes AM et al. (2011-01-01), Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood, 118(18):5031-9.
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Species: Human
Sample Types: Cell Culture Supernates
Wu MH et al. (2011-01-01), Targeting Galectin-1 in Carcinoma-Associated Fibroblasts Inhibits Oral Squamous Cell Carcinoma Metastasis by Downregulating MCP-1/CCL2 Expression. Clin. Cancer Res., 17(6):1306-16.
PMID: 21385934 -
Species: Human
Sample Types: Cell Culture Supernates
Park HD et al. (2011-01-01), Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation. Oncogene, 30(2):201-11.
PMID: 20802527 -
Species: Human
Sample Types: Cell Culture Supernates
Tormakangas L et al. (2010-01-01), Chlamydia pneumoniae infection in polarized epithelial cell lines. Infect. Immun., 78(6):2714-22.
PMID: 20351147 -
Species: Human
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Gannon PO et al. (2010-01-01), Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer. PLoS ONE, 5(8):e12107.
PMID: 20711410 -
Species: Human
Sample Types: Cell Culture Supernates
Chikanishi T et al. (2010-01-01), Glucose-induced expression of MIP-1 genes requires O-GlcNAc transferase in monocytes. Biochem. Biophys. Res. Commun., 394(4):865-70.
PMID: 20206135 -
Species: Human
Sample Types: Cell Culture Supernates
Droin N et al. (2010-01-01), Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia. Blood, 115(1):78-88.
PMID: 19864642 -
Species: Human
Sample Types: Tissue Homogenates
Perin L et al. (2010-01-01), Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS ONE, 5(2):e9357.
PMID: 20195358 -
Species: Human
Sample Types: Cell Culture Supernates
Kenig S et al. (2010-01-01), Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett., 289(1):53-61.
PMID: 19700239 -
Species: Human
Sample Types: Cell Culture Supernates
Baston-Bust DM et al. (2010-01-01), Syndecan-1 knock-down in decidualized human endometrial stromal cells leads to significant changes in cytokine and angiogenic factor expression patterns. Reprod. Biol. Endocrinol., 8(0):133.
PMID: 21044331 -
Species: Human
Sample Types: Cell Lysates
Nold MF et al. (2010-01-01), IL-37 is a fundamental inhibitor of innate immunity. Nat. Immunol., 11(11):1014-22.
PMID: 20935647 -
Species: Human
Sample Types: Cell Culture Supernates
Neerincx A et al. (2010-01-01), A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses. J. Biol. Chem., 285(34):26223-32.
PMID: 20538593 -
Species: Human
Sample Types: Cell Culture Supernates
Guzzo C et al. (2010-01-01), Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes. J. Biol. Chem., 285(32):24404-11.
PMID: 20519510 -
Species: Human
Sample Types: Cell Culture Supernates
Ikeda H et al. (2010-01-01), PI3K/p110{delta} is a novel therapeutic target in multiple myeloma. Blood, 116(9):1460-8.
PMID: 20505158 -
Species: Primate - Macaca fuscata (Japanese Macaque)
Sample Types: Plasma
Grayson BE et al. (2010-01-01), Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology, 151(4):1622-32.
PMID: 20176722 -
Species: Human
Sample Types: Cell Culture Supernates
Kaler P et al. (2009-01-01), Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3. Oncogene, 28(44):3892-902.
PMID: 19701245 -
Species: Human
Sample Types: Cell Culture Supernates
Mizutani K et al. (2009-01-01), Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. J. Cell. Biochem., 106(4):563-9.
PMID: 19170075 -
Species: Human
Sample Types: Cell Culture Supernates
Njau F et al. (2009-01-01), In vitro neutralization of tumor necrosis factor-alpha during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny. FEMS Immunol. Med. Microbiol., 55(2):215-25.
PMID: 19281567 -
Species: Human
Sample Types: Serum
Mohri Y et al. (2009-01-01), Identification of macrophage migration inhibitory factor and human neutrophil peptides 1-3 as potential biomarkers for gastric cancer. Br. J. Cancer, 101(2):295-302.
PMID: 19550422 -
Species: Human
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Hao Q et al. (2009-01-01), Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. Am. J. Physiol., Cell Physiol., 296(4):C821-7.
PMID: 19176759 -
Species: Human
Sample Types: Cell Lysates
Smith AM et al. (2009-01-01), Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J. Exp. Med., 206(9):1883-97.
PMID: 19652016 -
Species: Mouse
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Sauer AV et al. (2009-01-01), ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency. Blood, 114(15):3216-26.
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Eid RE et al. (2009-01-01), Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 119(10):1424-32.
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Lengelle J et al. (2008-01-01), Soluble CD40 ligand as a biomarker for storage-related preanalytic variations of human serum. Cytokine, 44(2):275-82.
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Feld M et al. (2008-01-01), Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection. J. Immunol., 180(10):6903-10.
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Alfaro-Moreno E et al. (2008-01-01), Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10. Eur. Respir. J., 32(5):1184-94.
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Marcondes AM et al. (2008-01-01), Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc. Natl. Acad. Sci. U.S.A., 105(8):2865-70.
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Nold MF et al. (2008-01-01), Endogenous IL-32 controls cytokine and HIV-1 production. J. Immunol., 181(1):557-65.
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Yang HT et al. (2007-01-01), IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells. Cell. Signal., 20(2):375-80.
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Swisher JF et al. (2007-01-01), Annexin A2 is a soluble mediator of macrophage activation. J. Leukoc. Biol., 82(5):1174-84.
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Fischer J et al. (2007-01-01), Induction of host chemotactic response by Encephalitozoon spp. Infect. Immun., 75(4):1619-25.
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Rudisch A et al. (), High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS ON10(4):e0124283.
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Customer Reviews for Proteome Profiler Human Cytokine Array Kit (11)
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Verified Customer | Posted 09/29/2021Excellent results
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Verified Customer | Posted 01/25/2017Tested condition media of MSCs from the umbilical cord co-cultured with NK cells. The goal of this experiments was to detect chages in inflammatory factors in the system when MSCs were cultured with NK cells. The lack of detected secreted proteins is promising because this suggests that MSCs do not up-regulate large inflammatory proteins following immune cell activation. Left image : MSC cultured in RPMI media (Control)Right image: MSC co-cultured with NK cells in same RPMI media
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FAQs for Proteome Profiler Human Cytokine Array Kit
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Will the Array identification number stamped on the Array membrane interfere with detection if it is not cut-off before the membrane is blocked?
The dye used for printing the Array identification number on the membranes will fluoresce and interfere with the LI-COR detection. It is critical that the number is cut off before beginning the experiment.
