R&D Systems Hematology Controls
R&D Systems has been at the forefront of the hematology clinical controls industry for several decades. By building on cutting-edge technologies and a deep understanding of hematology testing requirements, we have established ourselves as a trusted partner for laboratories worldwide.

Whole blood hematology controls to verify hematology platforms measuring complete blood counts including 5-part white blood cell differentials.
CBC-5D
CBC-5D is a tri-level control designed for Beckman Coulter LH 500, LH 700 Series, and DxH 800/600 hematology analyzers.
CBC-X
CBC-X is a tri-level control formulated for Sysmex XE-5000, XE-2100, XT-4000i, XT-2000i, XN-Series, XT-1800i, and XS-1000i hematology analyzers.
CBC-3K
CBC-3K is a tri-level control for monitoring Abbott hematology analyzers such as CELL-DYN 3200, 3500, 3700, Sapphire, Ruby as well as manual methods.
CBC-5DMR
CBC-5DMR is a tri-level control designed for monitoring Mindray hematology analyzers. Not available in the US.
CBC-DH
CBC-DH is a tri-level control compatible with Genrui, Dymind, Wheisman, Landwind, and CPC Diagnostics hematology analyzers.
CBC-SYS
CBC-SYS is a tri-level control designed for monitoring Sysmex SF-3000 and SE-series analyzers and is compatible with Dirui hematology systems.
CBC-Tech
CBC-Tech is a tri-level control designed for monitoring Siemens Advia hematology analyzers
CBC-PIX
CBC-PIX is an assayed whole blood control designed with assay values for the PixCell HemoScreen analyzer.
Whole blood hematology controls to verify hematology platforms measuring complete blood counts including 3-part white blood cell differentials.
CBC-3D®
CBC-3D is a tri-level control compatible with many automated hematology platforms with assay sheets available for Abbott CELL-DYN Emerald instruments.
CBC-ST Plus
CBC-ST Plus is a tri-level control for monitoring the Sysmex KX-21/KX-21N analyzers.
CBC-3D for Mindray
CBC-3D for Mindray is a tri-level control for monitoring Mindray BC-3200, BC-3600, BC-2600 Vet and BC-2800 Vet analyzers.
Whole blood hematology calibrators to standardize and validate hematology analyzers for various blood parameters, ensuring accurate and reliable results.
CBC-CAL PLUS
CBC-CAL PLUS is designed for the calibration of Beckman analyzers. Values are provided for WBC, RBC, HGB, MCV and PLT parameters.
CD-Cal
CD-Cal is designed for calibration of Abbott CELL-DYN hematology analyzers. Values are provided for WBC, RBC, RBCo, Hgb, MCV, PLTo, PLTi and MPV.
Tech-Cal
Tech-Cal is designed for calibration of Siemens ADVIA 120, 2120, 2120i and 60 hematology analyzers. Values include WBCB (WBCP), RBC, Hgb, MCV, CHCM%, Plt, NEUTx%, and NEUTy%.
NEK-CAL
The NEK- CAL is designed for calibration of Sysmex XE-2100/2100D and KX-21/KX-21N hematology analyzers. Values are provided for WBC, RBC, Hgb, MCV, Hct, and Plt.
CBC-CAL PLUS for Mindray
CBC-CAL PLUS for Mindray is designed for the calibration of Mindray hematology analyzers. Values are provided for WBC, RBC, HGB, MCV and PLT parameters.
Whole blood controls for use with flow cytometry platforms.
StatusFlow
StatusFlow is a stable preparation of human peripheral leukocytes and erythrocytes designed for use as a control in immunophenotyping when evaluating RBC lysis, antibody reactivity, instrument set-up, and instrument performance by flow cytometry.
StatusFlowPRO
StatusFlowPRO is a bi-level whole blood control containing human stem cells that can be used with most flow cytometry methods for identifying CD34+ cells.
StatusFlowLO
StatusFlowLO is designed to team with StatusFlow to provide a whole blood reference control for monitoring low CD3+/CD4+ cell counts.
FETALtrol
FETALtrol is a tri-level control intended for hospital clinical laboratories and reference laboratories testing for fetomaternal hemorrhage.
Whole blood reticulocyte controls for automated platforms and manual methods.
R&D Retic
R&D Retic is a tri-level whole blood reticulocyte control for manual counting methods. Assay values are provided for the manual method and manual with Miller ocular.
R&D Retic-I
R&D Retic-I is a tri-level whole blood reticulocyte control for manual and automated counting methods. Assay values are provided for the manual method, manual with Miller ocular, and flow cytometers using Thiazole Orange.
ADVIA® Retic Plus
R&D ADVIA Retic Plus is a tri-level whole blood reticulocyte control for the ADVIA 120, 2120 and 2120i analyzers. The bar-coded assay table provides values for Retic%, Retic RBC, MCVg, MCVr, CHCMg, CHCMr, CHg, and CHr.
R&D Retic-I for DxH 800
R&D Retic-I for DxH 800 is a tri-level whole blood reticulocyte control for automated counting methods with assay values for the Beckman Coulter UniCel DxH 800/600.
R&D 3K Retic
R&D 3K Retic is a bi-level whole blood reticulocyte control designed specifically for the Abbott CELL-DYN 3200 and Ruby hematology analyzers.
R&D 4K Retic
R&D 4K Retic is a bi-level whole blood reticulocyte control designed specifically for Abbott CELL-DYN Sapphire hematology analyzers. Assay values are also provided for manual methods.
XERet Control
XERet Control is a tri-level whole blood reticulocyte control designed specifically for Sysmex XE-5000, XE-2100, XT-2000i and XT-4000i hematology analyzers.
Whole blood hematology controls to verify performance of automated ESR platforms.
SEDRite Plus
SEDRite Plus is a bi-level control formulated to provide values in the clinically normal and elevated ranges, and is designed to monitor erythrocyte sedimentation rate (ESR) values obtained from manual and automated ESR methods.
SEDRite III
SEDRite III is a bi-level control designed specifically for the Sedimat 15 analyzer, with values in the clinically normal and elevated ranges.
Whole blood controls for POC hematology analyzers.
HC WBC
HC WBC is a tri-level control used to monitor values obtained from a HemoCue WBC system, provided in 1.5 mL plastic dropper vials.
HGB Extended Control
HGB Extended Control is an assayed control designed to monitor values obtained from the HemoCue Hemoglobin Photometer.
R&D Glu/Hgb
R&D Glu/Hgb is a tri-level control used to monitor the precision and accuracy of HemoCue B-Glucose, Glucose 201, and Hb 201+ analyzers, provided in 1.5 mL plastic dropper vials.
CBC-7 HemoCue
CBC-7 HemoCue is a tri-level control used to monitor hemoglobin values obtained from the HemoCue hemoglobin photometer.
CBC-PIX
CBC-PIX is an assayed whole blood control designed with assay values for the PixCell HemoScreen analyzer.
PLATELET-TROL® Extended
PLATELET-TROL Extended is a control designed specifically for monitoring the elevated platelet ranges of hematology analyzers. Assay values are available for Abbott Cell-Dyn Sapphire, HORIBA Micros 60 and Pentra 80, Beckman Coulter LH700 Series, Siemens ADVIA 120 and 2120, and Sysmex XE-2100 and XE-2100D.
R&D LeukoReduced RBC Control
LeukoReduced RBC Control is a bi-level control product to monitor flow cytometer and Nageotte Chamber methods for quantification of residual leukocytes in leukoreduced red blood cell products.
R&D LeukoReduced PLT Control
LeukoReduced PLT Control is a bi-level control product to monitor flow cytometer and Nageotte Chamber methods for quantification of residual leukocytes in leukoreduced platelet products.
R&D LeukoReduced RBC/PLT Control
LeukoReduced RBC/PLT control is a bi-level control product designed to monitor flow cytometer and Nageotte Chamber methods for quantification of residual leukocytes in LeukoReduced red blood cell and platelet products.
CBC-7
CBC-7 is a tri-level control used for Manual Methods, semi-automated and automated instruments capable of measuring up to seven parameters.
R&D Body Fluid
R&D Body Fluid is a bi-level control used to monitor total cell counts performed manually using a hemocytometer.
R&D Body Fluid-I Control
R&D Body Fluid-I Control is an assayed hematology control intended to monitor the reliability of hematology instruments that quantitatively measure red and white blood cell counts in cerebrospinal fluids, serous fluids, and synovial fluids.
CBC-LINE
CBC-LINE Ultra Low
CBC-LINE Ultra Low Plus RBC
CBC-LINE for HemoCue
CBC-LINE contains pre-diluted WBC, RBC/Hgb, and PLT levels appropriate for use in establishing reportable ranges. Kits are customized to the reportable range capabilities of all major hematology analyzers to best suit your needs. When CBC-LINE kits are used in combination with independently verified and documented calibration, the information can be used to establish the range of lowest and highest values that can be accurately reported by the hematology analyzer. Each kit includes one instrument evaluation report at no extra charge.
PLT-LINE
PLT-LINE contains pre-diluted platelet levels appropriate for use in instrument calibration verification. Kits are customized to the reportable range capabilities of all major hematology analyzers to best suit your needs. When PLT-LINE kits are used in combination with independently verified and documented calibration, the information can be used to establish the range of lowest and highest values that can be accurately reported by the hematology analyzer. Each kit includes one instrument evaluation report at no extra charge.
RET-LINE
RET-LINE contains a series of pre-diluted reticulocyte concentrations for use in establishing the reportable range. Kits are customized to the reportable range capabilities of all major hematology analyzers to provide a kit that meets your needs. Each kit includes one instrument evaluation report at no extra charge.
Resources and Related Products
Custom Capabilities
Our offerings go beyond our catalog to provide exactly the services and products you need:
- New Control Development
- Control Verification and Validation
- Custom Labeling and Kitting
- Value Assignment Services
Proficiency Testing/EQA Materials
- Catalog
- Others
Quality System
- Controls are manufactured in compliance with international regulatory standards and guidelines, including ISO 13485 and FDA regulations. This commitment to regulatory compliance helps laboratories meet stringent quality control requirements.

Additional IVD Capabilities
Custom Controls & Calibrators
Custom Controls & Calibrators
- Hematology/Flow Cytometry
- Cardiac Markers
- Traumatic Brain Injury (TBI)
- Therapeutic Drug Monitoring (TDM)
- Serum Proteins
- Urinalysis & Urine Chemistry
- Blood Gas/Electrolytes
- CO-Oximetry
- Glucose/Diabetes
- Coagulation
Proficiency Testing/EQA Materials
Proficiency Testing/EQA Materials
- 40 years of experience in EQC products
- Used widely in the EQC industry
- Customizable matrix & format
- Broad analyte portfolio
- Controls with clinically significant levels and high specificity
- High commutability
- Significant material shelf life