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New Small Molecules & Peptides

TM 38837 | 7131

  • Highly potent cannabinoid receptor 1 (CB1) inverse agonist
  • Peripherally restricted

ARCC | 7254

  • Potent and selective androgen receptor Degrader
  • Inhibits proliferation of prostate cancer cell lines
  • Negative control also available

iHAP1 | 7303

  • Allosteric activator of protein phosphatase 2A (PP2A)
  • Inhibits proliferation of T-ALL leukemia cell lines

Featured Small Molecule Product Types

Compound Libraries

The Tocriscreen™ range of bioactive compound libraries are collections of small molecules designed for use in assays for target validation, tool compound identification, receptor de-orphanization and assay development. The range includes libraries covering a diverse range of research areas and targets, as well as focused libraries for specific targets and drug repurposing.

Chemogenetics

Chemogenetic compounds, such as DREADD ligands and PSEMs, act at genetically modified GPCRs and ion channels, respectively. They enable control of neuronal activity, and investigation of downstream signaling pathways, by initiating a signal cascade from a GPCR or opening of an ion channel pore. 

Fluorescent Probes and Dyes

Fluorescent probes and dyes allow visualization of intracellular structures and individual proteins, and determination of cell types, in live and fixed cells with high sensitivity and selectivity. Our range includes Janelia Fluor® Dyes, cytoskeletal and microtubule probes as well as innovative probes for imaging bacteria. 

Featured Small Molecule Research Resources

Targeted Protein Degradation Brochure

Targeted Protein Degradation Research Guide

Targeted Protein Degradation (TPD) is an innovative method to knock-down your protein of interest, using small molecules. Our TPD Research Product Guide outlines tools and services from Bio-Techne to support your TPD research, including Active Degraders, Degrader Building Blocks, and Proteins and Assays for protein degradation. 

SARS-CoV-2

Small Molecules for COVID-19 Research

Explore compounds for the investigation of viral cell entry, viral replication and cytokine storm in SARS-CoV-2 infection in our new research area. 

Products by Application, Type or Technique

Background Information