Is PBS a suitable alternative with which to formulate the Reagent Diluent?

Name: Human IL-8/CXCL8 DuoSet ELISA
Brand: R&D Systems
SKU: DY208
Rating: 5 (21 reviews)

Our lab has determined that Tris-buffered saline generates optimal assay performance in comparison to PBS for this assay. This assay is validated with Reagent Diluent formulated using Tris-buffered saline.

Human IL-8/CXCL8 DuoSet ELISA

R&D Systems, Inc. a Bio-Techne Brand

Catalog # DY208

Citations (388)

(21)

Product Datasheet / COA / SDS

Catalog #

Availability

Size / Price

Qty

Setting the standard in quality research reagents

Key Product Details

Assay Type:	Solid Phase Sandwich ELISA
Assay Range:	31.2 - 2,000 pg/mL
Sample Types:	Cell culture supernates, serum, and plasma Note: Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet
Human IL-8/CXCL8 DuoSet ELISA Features:	Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time Development protocols are provided to guide further assay optimization Assay can be customized to your specific needs Economical alternative to complete kits

View Full Technical Details for Human IL-8/CXCL8 DuoSet ELISA

Summary for Human IL-8/CXCL8 DuoSet ELISA

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human CXCL8/IL-8. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Specifications for Human IL-8/CXCL8 DuoSet ELISA

Assay Format	96-well strip plate (sold separately)
Sample Volume Required	100 µL
Reactivity	Human
Specificity	Please see the product datasheet
Detection Method	Colorimetric ELISA - 450nm (TMB)
Conjugate	Biotin
Label	HRP
Measurement	Quantitative ELISA
Sufficient Materials	For fifteen 96-well plates*

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Kit Contents for Human IL-8/CXCL8 DuoSet ELISA

Capture Antibody
Detection Antibody
Recombinant Standard
Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Block Buffer: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Reagent Diluent: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCI) pH 7.2-7.4, 0.2 μm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data Examples for Human IL-8/CXCL8 DuoSet ELISA

	Human IL-8 / CXCL8 ELISA Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-8/CXCL8

Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent.

Multiple isoforms of IL-8 are generated through both alternative splicing and differential proteolytic cleavage. In humans, alternative splicing generates an iso-form with an eleven aa substitution at the C-terminus. Proteolytic processing results in N-terminal truncation of IL-8 and is likely a cell-specific event. For example, fibroblasts and endothelial cells generate the 1-77 form by cleaving IL-8 following Glu21, while monocytes and lymphocytes generate the 6-77 form by cleaving following Leu25. These truncated forms generally show increased bioactivity, particularly through the CXCR1 receptor. IL-8 can also undergo citrullination on Arg27 of the precursor, a modification that increases its half-life and ability to induce leukocytosis. A wide variety of cells secrete IL-8 including monocytes and neutrophils, fibroblasts and keratinocytes, mast cells, visceral smooth muscle cells, dendritic cells, type II great alveolar cells, and endothelial cells.

IL-8 bioactivity is mediated through two G-protein-coupled receptors, termed CXCR1/IL-8 RA and CXCR2/IL-8 RB. CXCR1 is 45-50 kDa in size and is used almost exclusively by IL-8. CXCR2 is 35-40 kDa in size and is used by nearly all CXC chemokines. Both CXCR1 and CXCR2 constitutively associate into functional homodimers. They can also heterodimerize, but these complexes dissociate following IL-8 binding. CXCR2 responds to low concentrations of IL-8 and is principally associated with chemotaxis and MMP-9 release. CXCR1, in contrast, responds to high concentrations of IL-8 and is associated with respiratory burst and phospholipase D2 activation. Thus, CXCR2 ligation induces leukocyte adhesion to activated vascular endothelium and migration to sites of inflammation, while CXCR1 ligation primes neutrophil antimicrobial activity. IL-8 can also form a complex with Serpin A1/alpha-1 Antitrypsin, and this prevents IL-8 interaction with CXCR1.

In addition to its pro-inflammatory effects, IL-8 is involved in angiogenesis and the pathogenesis of atherosclerosis and cancer. It induces VEGF expression in vascular endothelial cells and functions as an autocrine factor for EC growth and angiogenesis. It is upregulated in atherosclerotic lesions and is elevated in the serum and cerebrospinal fluid following myocardial infarction. In cancer, IL-8 promotes epithelial-mesenchymal transition as well as tumor cell invasiveness and metastasis.

Item	Value
Long Name	Interleukin 8
Entrez Gene IDs	3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names	3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP-1TSG-1, GCP1, IL-8, IL8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, MONAP, MONAPGCP1, NAF, NAP-1NAP1, NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1, interleukin 8, member 8

Citations for Human IL-8/CXCL8 DuoSet ELISA (388)

Showing 1 - 10 of 388 citations Showing All

Filter By:

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Human IL-8/CXCL8 DuoSet ELISA include:

Species: Human
Sample Types: Cell Culture Supernates

E Fournier et al. (2023-01-01), Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models Journal of Hazardous Materials, 442(0):130010.
PMID: 36182891
Species: Human
Sample Types: Cell Culture Supernates

E Fournier et al. (2023-01-01), Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model Journal of Hazardous Materials, 443(0):130383.
PMID: 36444070
Species: Human
Sample Types: Cell Culture Supernates

H Han et al. (2023-01-01), Multi-Species Probiotic Strain Mixture Enhances Intestinal Barrier Function by Regulating Inflammation and Tight Junctions in Lipopolysaccharides Stimulated Caco-2 Cells Microorganisms, 11(3).
PMID: 36985228
Species: Human
Sample Types: Cell Culture Supernates

M Liu et al. (2023-01-01), Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 18(1):e0280385.
PMID: 36662769
Species: Human
Sample Types: Plasma

DT Spiegelbur et al. (2023-01-01), Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model PLoS ONE, 18(1):e0280069.
PMID: 36634087
Species: Human
Sample Types: Cell Culture Supenates

T Pirker et al. (2023-01-01), Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8 Journal of ethnopharmacology, 0(0):116328.
PMID: 36870464
Species: Human
Sample Types: Blister Fluid

G Szylar et al. (2022-01-01), A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site Scientific Reports, 12(1):3990.
PMID: 35256717
Species: Human
Sample Types: Cell Culture Supernates

AR Cátala-Val et al. (2022-01-01), E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing Cells, 11(5).
PMID: 35269394
Species: Human
Sample Types: Cell Culture Supernates

A Divoux et al. (2022-01-01), Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women Cells, 11(5).
PMID: 35269469
Species: Human
Sample Types: Serum

E Lieschke et al. (2022-01-01), Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence Cell Death and Differentiation, 0(0).
PMID: 35264779
Species: Human
Sample Types: Serum

T Walle et al. (2022-01-01), Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 Science Advances, 8(12):eabh4050.
PMID: 35319989
Species: Human
Sample Types: Cell Culture Supernates

B Grüner et al. (2022-01-01), Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up PloS Neglected Tropical Diseases, 16(2):e0010099.
PMID: 35108275
Species: Human
Sample Types: Cell Culture Supernates

Y Gu et al. (2022-01-01), MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema Oxidative Medicine and Cellular Longevity, 2022(0):9300269.
PMID: 35035670
Species: Human
Sample Types: Cell Culture Supernates

K Nakamura et al. (2022-01-01), Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation Scientific Reports, 12(1):5181.
PMID: 35410994
Species: Human
Sample Types: Cell Culture Supernates

ME Nordberg et al. (2022-01-01), Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects Environment international, 158(0):106997.
PMID: 34991257
Species: Human
Sample Types: Cell Culture Supernates

M Dolci et al. (2022-01-01), In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release International Journal of Molecular Sciences, 23(7).
PMID: 35409421
Species: Human
Sample Types: Cell Culture Supernates

H Janbazacya et al. (2022-01-01), Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability Cytokine, 154(0):155878.
PMID: 35405483
Species: Human
Sample Types: Cell Culture Supernates

S Novello et al. (2022-01-01), Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts Pharmaceutics, 14(4).
PMID: 35456563
Species: Human
Sample Types: Amniotic Fluid

S Hong et al. (2022-01-01), Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length PLoS ONE, 17(2):e0263586.
PMID: 35130326
Species: Human
Sample Types: Cell Culture Supernates

S Offer et al. (2022-01-01), Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air-Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs) Environmental health perspectives, 130(2):27003.
PMID: 35112925
Species: Human
Sample Types: Cell Culture Supernates

V Schimek et al. (2022-01-01), Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment Cell Death Disease, 2022;13(2):113.
PMID: 35121727
Species: Human
Sample Types: Cell Culture Supernates

J Queen et al. (2022-01-01), Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models MBio, 0(0):e0299121.
PMID: 35130731
Species: Human
Sample Types: Plasma

OF McElvaney et al. (2022-01-01), Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications EBioMedicine, 77(0):103894.
PMID: 35217407
Species: Human
Sample Types: Serum

S Saxena et al. (2022-01-01), Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma American journal of cancer research, 12(1):68-90.
PMID: 35141005
Species: Human
Sample Types: Cell Culture Supernates

C Sun et al. (2022-01-01), Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement International Journal of Molecular Sciences, 23(3).
PMID: 35163446
Species: Human
Sample Types: Cell Culture Supernates

Y Zhan et al. (2022-01-01), Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease Respiratory Research, 23(1):120.
PMID: 35550579
Species: Human
Sample Types: Cell Culture Supernates

P Globig et al. (2022-01-01), Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model Bioactive materials, 16(0):320-333.
PMID: 35386318
Species: Human
Sample Types: Cell Culture Supernates

Q Liu et al. (2022-01-01), Inhibition of Spleen Tyrosine Kinase Restores Glucocorticoid Sensitivity to Improve Steroid-Resistant Asthma Frontiers in Pharmacology, 13(0):885053.
PMID: 35600871
Species: Human
Sample Types: Plasma

JT de Kay et al. (2022-01-01), Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus Cellular Signalling, 96(0):110360.
PMID: 35609807
Species: Mouse
Sample Types: Cell Culture Supernates

DC Humphries et al. (2022-01-01), Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation Frontiers in Pharmacology, 13(0):949264.
PMID: 36003515
Species: Human
Sample Types: Cell Culture Supernates

L Homann et al. (2022-01-01), IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma Cells, 11(9).
PMID: 35563820
Species: Human
Sample Types: Cell Culture Supernates

M Busch et al. (2022-01-01), Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells Biomolecules, 12(8).
PMID: 36008988
Species: Human
Sample Types: Cell Culture Supernates

L Sansone et al. (2022-01-01), Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity International Journal of Molecular Sciences, 23(16).
PMID: 36012747
Species: Human
Sample Types: Cell Culture Supernates

C Amormino et al. (2022-01-01), SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity Cells, 11(16).
PMID: 36010602
Species: Human
Sample Types: Cell Culture Supernatants

M Patankar et al. (2022-01-01), Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts International Journal of Molecular Sciences, 23(18).
PMID: 36142285
Species: Human
Sample Types: Cell Culture Supernates

M Anselmi et al. (2022-01-01), Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression Cancers, 14(14).
PMID: 35884452
Species: Human
Sample Types: Cell Culture Supernates

A Moniot et al. (2022-01-01), Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds International Journal of Molecular Sciences, 23(13).
PMID: 35806233
Species: Human
Sample Types: Cell Culture Supernates

S Upadhyay et al. (2022-01-01), Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models Oncogene, 10(6).
PMID: 35736886
Species: Human
Sample Types: Cell Culture Supernates

AA Lozhkov et al. (2022-01-01), Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated Response Viruses, 14(10).
PMID: 36298646
Species: Human
Sample Types: Cell Culture Supernates

EM Smith et al. (2022-01-01), The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model PloS Neglected Tropical Diseases, 16(7):e0010638.
PMID: 35881640
Species: Human
Sample Types: Cell Culture Supernates

S Rutecki et al. (2022-01-01), Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 15(1):87.
PMID: 35883110
Species: Human
Sample Types: Cell Culture Supernates

P Marona et al. (2022-01-01), Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation Cell Death Disease, 2022;13(9):814.
PMID: 36138026
Species: Human
Sample Types: Cell Culture Supernates

T Luong et al. (2022-01-01), Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition BMC Cancer, 22(1):1255.
PMID: 36461015
Species: Human
Sample Types: Cell Culture Supernates

H Stölting et al. (2022-01-01), Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1 Mucosal Immunology, 0(0).
PMID: 35840680
Species: Human
Sample Types: Cell Culture Supernates

L Zuliani-Al et al. (2022-01-01), Evasion of cGAS and TRIM5 defines pandemic HIV Nature Microbiology, 7(11):1762-1776.
PMID: 36289397
Species: Human
Sample Types: Cell Culture Supernates

J Yang et al. (2022-01-01), KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer Cancer Research, 0(0):OF1-OF14.
PMID: 36306422
Species: Human
Sample Types: Plasma

LAC Teixeira et al. (2022-01-01), Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 11(23).
PMID: 36498747
Species: Human
Sample Types: Cell Culture Supernates

LAJ Feather et al. (2022-01-01), Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 12(1):12448.
PMID: 35859154
Species: Human
Sample Types: Cell Culture Supernates

K Ueno-Shuto et al. (2022-01-01), A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells International Journal of Molecular Sciences, 23(14).
PMID: 35887095
Species: Human
Sample Types: Cell Culture Supernates

Y Lyu et al. (2022-01-01), Digested Human Colostrum Reduces Interleukin-8 Production in Induced Human Intestinal Epithelial Cells Nutrients, 14(14).
PMID: 35889744
Species: Human
Sample Types: Cell Culture Supernates

Q Huang et al. (2022-01-01), Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium Oxidative Medicine and Cellular Longevity, 2022(0):7067623.
PMID: 36578523
Species: Human
Sample Types: Cell Culture Supernates

TY Chu et al. (2022-01-01), GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation Nature Communications, 13(1):6385.
PMID: 36302784
Species: Human
Sample Types: Cell Culture Supernates

B Saravi et al. (2022-01-01), In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells Cells, 11(21).
PMID: 36359814
Species: Human
Sample Types: Cell Culture Supernates

M Hornschuh et al. (2022-01-01), Negative Magnetic Sorting Preserves the Functionality of Ex Vivo Cultivated Non-Adherent Human Monocytes Biology, 11(11).
PMID: 36358284
Species: Human
Sample Types: Cell Culture Supernates

KEC Blokland et al. (2022-01-01), Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts Frontiers in Pharmacology, 13(0):989169.
PMID: 36408252
Species: Human
Sample Types: Cell Culture Supernates

K Shabir et al. (2022-01-01), Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 24(1).
PMID: 36613673
Species: Human
Sample Types: Cell Culture Supernates

LU Teufel et al. (2022-01-01), Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 162(0):156102.
PMID: 36476991
Species: Human
Sample Types: Cell Culture Supernates

MS Coates et al. (2021-01-01), Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway PLoS ONE, 16(2):e0246050.
PMID: 33524056
Species: Human
Sample Types: Cell Culture Supernates

Y Hosokawa et al. (2021-01-01), The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells BioMed Research International, 2021(0):8826586.
PMID: 33575345
Species: Human
Sample Types: Cell Culture Supernates

N Kwak et al. (2021-01-01), Synergistic cycles of protease activity and inflammation via PPAR&gamma degradation in chronic obstructive pulmonary disease Experimental Molecular Medicine, 2021;0(0).
PMID: 34021254
Species: Bovine
Sample Types: Cell Culture Supernates

PP Nunes et al. (2021-01-01), Production of IL-1&beta, IL-6 and CXCL8 by endometrium of crossbred heifers stimulated with various pathogen-associated molecular patterns Animal reproduction science, 228(0):106736.
PMID: 33752096
Species: Human
Sample Types: Cell Culture Supernates

MS Phuong et al. (2021-01-01), Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response Cell Death Disease, 2021;12(3):241.
PMID: 33664232
Species: Human
Sample Types: Cell Culture Supernates

JI Alexander et al. (2021-01-01), Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma Scientific Reports, 11(1):3802.
PMID: 33589694
Species: Human
Sample Types: Cell Culture Supernates

M Tong et al. (2021-01-01), Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release Journal of reproductive immunology, 145(0):103306.
PMID: 33725528
Species: Human
Sample Types: Plasma

GK Vasileiadi et al. (2021-01-01), Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation Biomolecules, 11(2).
PMID: 33669910
Species: Human
Sample Types: Cell Culture Supernates

P Kvacskay et al. (2021-01-01), Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy? Arthritis Research Therapy, 2021;23(1):56.
PMID: 33588937
Species: Human
Sample Types: Cell Culture Supernates

YC Hu et al. (2021-01-01), Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production Arthritis Research Therapy, 2021;23(1):171.
PMID: 34134755
Species: Human
Sample Types: Cell Culture Supernates

M Dabaghi et al. (2021-01-01), PHAIR: a biosensor for pH measurement in air-liquid interface cell culture Scientific Reports, 11(1):3477.
PMID: 33568708
Species: Human
Sample Types: Serum

H Dai et al. (2021-01-01), Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication Bone marrow transplantation, 0(0).
PMID: 33517355
Species: Human
Sample Types: Cell Culture Supernates

M Heydarian et al. (2021-01-01), Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity Journal of tissue engineering, 12(0):2041731420988.
PMID: 33796248
Species: Human
Sample Types: Cell Culture Supernates

M Paximadis et al. (2021-01-01), Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations Cytokine, 0(0):155489.
PMID: 33814271
Species: Human
Sample Types: cell culture supernatant

SH Kim et al. (2021-01-01), Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets Toxics, 9(3).
PMID: 33803047
Species: Human
Sample Types: Cell Culture Supernates

L Wang et al. (2021-01-01), Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice Nature Genetics, 53(4):500-510.
PMID: 33782605
Species: Human
Sample Types: Cell Culture Supernates

X Zhou et al. (2021-01-01), Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion Scientific Reports, 11(1):7360.
PMID: 33795727
Species: Human
Sample Types: Cell Culture Supernates

SM Anil et al. (2021-01-01), Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages Scientific Reports, 11(1):1462.
PMID: 33446817
Species: Human
Sample Types: Cell Culture Supernates

SL Mathiasen et al. (2021-01-01), Bacterial genotoxins induce Tï¿½cell senescence Cell Reports, 35(10):109220.
PMID: 34107253
Species: Mouse
Sample Types: Cell Culture Supernates

M Busch et al. (2021-01-01), An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles Chemosphere, 284(0):131345.
PMID: 34216924
Species: Human
Sample Types: Cell Culture Supernates

M Sueiro-Oli et al. (2021-01-01), Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response PloS Biology, 19(6):e3001247.
PMID: 34061822
Species: Human
Sample Types: Cell Culture Supernates

KEC Blokland et al. (2021-01-01), Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM Cells, 10(7).
PMID: 34209854
Species: Human
Sample Types: Cell Culture Supernates

JS Bourgeois et al. (2021-01-01), ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice PloS Pathogens, 17(7):e1009713.
PMID: 34242364
Species: Human
Sample Types: Serum

LE Cabrera et al. (2021-01-01), Characterization of low-density granulocytes in COVID-19 PloS Pathogens, 17(7):e1009721.
PMID: 34228753
Species: Human
Sample Types: Cell Culture Supernates

N Niu et al. (2021-01-01), IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming Oncogenesis, 10(9):65.
PMID: 34588424
Species: Human
Sample Types: Cell Culture Supernates

B Falcones et al. (2021-01-01), Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells Polymers, 13(14).
PMID: 34301107
Species: Human
Sample Types: Cell Culture Supernates

AF Santos et al. (2021-01-01), The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways Journal of ethnopharmacology, 0(0):114512.
PMID: 34384848
Species: Human
Sample Types: Cell Culture Supernates

E Wirthgen et al. (2021-01-01), Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes Biology, 10(8).
PMID: 34439980
Species: Human
Sample Types: Plasma

T Koudstaal et al. (2021-01-01), Plasma markers in pulmonary hypertension subgroups correlate with patient survival Respiratory Research, 22(1):137.
PMID: 33947407
Species: Human
Sample Types: Cell Culture Supernates

J Cui et al. (2021-01-01), The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells PloS Pathogens, 17(8):e1009787.
PMID: 34339468
Species: Human
Sample Types: Cell Culture Supernates

N Rufo et al. (2021-01-01), Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting Cell Death and Differentiation, 0(0).
PMID: 34453119
Species: Human
Sample Types: Plasma

G Dunsmore et al. (2021-01-01), Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 19(8):e3001387.
PMID: 34411088
Species: Human
Sample Types: Cell Culture Supernates

SR Bruno et al. (2021-01-01), DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 22(20).
PMID: 34681784
Species: Human
Sample Types: Cell Culture Supernates

N Jones et al. (2021-01-01), Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 12(1):1209.
PMID: 33619282
Species: Human
Sample Types: Cell Culture Supernates

L Kandilogia et al. (2021-01-01), Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis Stem Cells International, 2021(0):9929461.
PMID: 34354753
Species: Human
Sample Types: Plasma

M Lesouhaiti et al. (2021-01-01), Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass Journal of leukocyte biology, 0(0).
PMID: 34425029
Species: Human
Sample Types: Cell Culture Supernates

MS Shaban et al. (2021-01-01), Multi-level inhibition of coronavirus replication by chemical ER stress Nature Communications, 12(1):5536.
PMID: 34545074
Species: Human
Sample Types: Cell Culture Supernates

P Jiang et al. (2021-01-01), Systematic investigation of cytokine signaling activity at the tissue and single-cell levels Nature methods, 18(10):1181-1191.
PMID: 34594031
Species: Human
Sample Types: Exhaled Breath Condensate (EBC)

MAR Brandao-Ra et al. (2021-01-01), Pulmonary function changes in older adults with and without metabolic syndrome Scientific Reports, 11(1):17337.
PMID: 34462482
Species: Human
Sample Types: Cell Culture Supernates

S Jamieson et al. (2021-01-01), Inflammatory responses to metal oxide ceramic nanopowders Scientific Reports, 11(1):10531.
PMID: 34006936
Species: Rat
Sample Types: Serum

L Feng et al. (2021-01-01), HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway Autophagy, 0(0):1-20.
PMID: 34024230
Species: Human
Sample Types: Recombinant Protein

S McKenna et al. (2021-01-01), A highly efficient method for the production and purification of recombinant human CXCL8 PLoS ONE, 16(10):e0258270.
PMID: 34653205
Species: Human
Sample Types: Cell Culture Supernates

A Tosi et al. (2021-01-01), Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma Biomedicines, 9(12).
PMID: 34944746
Species: Human
Sample Types: Cell Culture Supernates

K Dull et al. (2021-01-01), miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes Scientific Reports, 11(1):21510.
PMID: 34728702
Species: Human
Sample Types: Cell Culture Supernates

M Guibourden et al. (2021-01-01), Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium Toxics, 9(6).
PMID: 34207749
Species: Human
Sample Types: Cell Culture Supernates

AA Giese et al. (2021-01-01), Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells Scientific Reports, 11(1):24230.
PMID: 34930929
Species: Human
Sample Types: Cell Culture Supernates

R Roca-Pinil et al. (2021-01-01), Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins Scientific Reports, 11(1):23798.
PMID: 34893661
Species: Human
Sample Types: Cell Culture Supernates

S Saberi et al. (2021-01-01), Infection with a hypervirulent strain of Helicobacter pylori primes gastric cells toward intestinal transdifferentiation Microbial pathogenesis, 162(0):105353.
PMID: 34896202
Species: Human
Sample Types: Cell Culture Supernates

M Rahman et al. (2021-01-01), Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity Viruses, 13(12).
PMID: 34960806
Species: Human
Sample Types: Cell Culture Supernates

Y Hosokawa et al. (2021-01-01), Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells Mediators of Inflammation, 2021(0):5535844.
PMID: 34335088
Species: Human
Sample Types: Cell Culture Supernates

HK Skovdahl et al. (2021-01-01), Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration Frontiers in Pharmacology, 12(0):679741.
PMID: 34054553
Species: Human
Sample Types: Cell Culture Supernates

Z Cui et al. (2021-01-01), Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction Cell Death Disease, 2021;12(8):775.
PMID: 34362880
Species: Human
Sample Types: Pleural Effusion

PH Lee et al. (2021-01-01), Higher CD4/CD8 ratio of pleural effusion predicts better survival for lung cancer patients receiving immune checkpoint inhibitors Scientific Reports, 11(1):9381.
PMID: 33931705
Species: Human
Sample Types: Cell Culture Supernates

X Zhu et al. (2021-01-01), Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis Frontiers in Physiology, 12(0):733650.
PMID: 34690806
Species: Human
Sample Types: Cell Culture Supernates

X He et al. (2021-01-01), LYSMD3: A mammalian pattern recognition receptor for chitin Cell Reports, 36(3):109392.
PMID: 34289364
Species: Human
Sample Types: Cell Lysates

L Liu et al. (2021-01-01), Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors Frontiers in Physiology, 12(0):732564.
PMID: 34671275
Species: Human
Sample Types: Saliva

W Johnston et al. (2021-01-01), Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients Scientific Reports, 11(1):9796.
PMID: 33963212
Species: Human
Sample Types: Cell Culture Supernates

T Furukawa et al. (2020-01-01), The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus Nat Commun, 11(1):427.
PMID: 31969561
Species: Human
Sample Types: Cell Culture Supernates

I Gomez et al. (2020-01-01), Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium Nat Commun, 11(1):214.
PMID: 31924781
Species: Human
Sample Types: Cell Culture Supernates

L Mercurio et al. (2020-01-01), Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses PLoS ONE, 15(4):e0222969.
PMID: 32352958
Species: Human
Sample Types: Tissue Culture Supernates

T O'Loughlin et al. (2020-01-01), OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion J. Cell. Sci., 0(0).
PMID: 32376785
Species: Human
Sample Types: Cell Culture Supernates

M Karmakar et al. (2020-01-01), N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis Nat Commun, 11(1):2212.
PMID: 32371889
Species: Human
Sample Types: Cell Culture Supernates

FJ Ryan et al. (2020-01-01), Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease Nat Commun, 11(1):1512.
PMID: 32251296
Species: Human
Sample Types: Cell Culture Supernates

A Strid Holm et al. (2020-01-01), Data describing expression of formyl peptide receptor 2 in human articular chondrocytes Data Brief, 31(0):105866.
PMID: 32637484
Species: Human
Sample Types: Cell Culture Supernates

VR Rodovalho et al. (2020-01-01), Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-&kappaB Pathway Front Microbiol, 11(0):1544.
PMID: 32733422
Species: Human
Sample Types: Whole Cells

HF Hazlett et al. (2020-01-01), Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival Sci Rep, 10(1):10935.
PMID: 32616918
Species: Human
Sample Types: Cell Culture Supernates

S Tumpara et al. (2020-01-01), The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore Front Pharmacol, 11(0):983.
PMID: 32719598
Species: Human
Sample Types: Cell Culture Supernates

AE Wyman et al. (2020-01-01), SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells Sci Rep, 10(1):12497.
PMID: 32719338
Species: Human
Sample Types: Cell Culture Supernates

M De Angelis et al. (2020-01-01), Diet influences the functions of the human intestinal microbiome Sci Rep, 10(1):4247.
PMID: 32144387
Species: Human
Sample Types: Cell Culture Supernates

B Wernly et al. (2020-01-01), Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction Cells, 9(2).
PMID: 31991811
Species: Human
Sample Types: Cell Supernates

F Kolonics et al. (2020-01-01), Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions J. Leukoc. Biol., 0(0).
PMID: 32946637
Species: Human
Sample Types: Cell Culture Supernates

G Kaufman et al. (2020-01-01), N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM Int J Mol Sci, 21(19).
PMID: 33023018
Species: Human
Sample Types: Cell Culture Supernates

R Kolahdouz- et al. (2020-01-01), Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells Journal of Cellular and Molecular Medicine, 0(0).
PMID: 33325132
Species: Human
Sample Types: Whole Cells

PT Tien et al. (2020-01-01), Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells Scientific Reports, 10(1):15702.
PMID: 32973190
Species: Human
Sample Types: Cell Culture Supernates

T Peeters et al. (2020-01-01), An observational study of innate immune responses in patients with acute appendicitis Sci Rep, 10(1):17352.
PMID: 33060696
Species: Human
Sample Types: Vaginal Swab

EJ Dela Cruz et al. (2020-01-01), Genetic variation in Toll-like receptor-5 and colonization with flagellated bacterial vaginosis-associated bacteria Infect Immun, 0(0).
PMID: 33199356
Species: Human
Sample Types: Cell Culture Supernates

M Tutter et al. (2020-01-01), Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy Mol Ther, 0(0).
PMID: 33068779
Species: Human
Sample Types: Saliva

I Patlan et al. (2020-01-01), Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions Cytokine, 137(0):155347.
PMID: 33128925
Species: Human
Sample Types: Cell Culture Supernates

H Salvator et al. (2020-01-01), Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 11(0):598702.
PMID: 33363471
Species: Human
Sample Types: Cell Culture Supernates

A Iannucci et al. (2020-01-01), Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding PLoS Pathog., 16(9):e1008811.
PMID: 32903274
Species: Human
Sample Types: Cell Culture Supernates

YD Jung et al. (2020-01-01), Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells Redox Biol, 37(0):101716.
PMID: 32961441
Species: Human
Sample Types: Cell Culture Supernates

S Niklander et al. (2020-01-01), ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes FEBS Open Bio, 0(0).
PMID: 33095981
Species: Human
Sample Types: Fecal Supernates

GJ Britton et al. (2020-01-01), SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19 medRxiv : the preprint server for health sciences, 0(0).
PMID: 32909002
Species: Human
Sample Types: Amniotic Fluid

HJ Kim et al. (2020-01-01), A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation PLoS ONE, 15(12):e0244720.
PMID: 33382822
Species: Human
Sample Types: Serum

M Kameda et al. (2020-01-01), CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features PLoS ONE, 15(11):e0241719.
PMID: 33137121
Species: Human
Sample Types: Cell Culture Supernates

LJ Williams et al. (2020-01-01), Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages International Journal of Environmental Research and Public Health, 18(1).
PMID: 33379200
Species: Human
Sample Types: Cell Culture Supernates

R Nallathamb et al. (2020-01-01), Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells Nutrients, 12(6).
PMID: 32492806
Species: Human
Sample Types: Placental Supernates

LM Gierman et al. (2020-01-01), TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies J. Leukoc. Biol., 0(0).
PMID: 32573856
Species: Human
Sample Types: Cell Culture Supernates

V Spiegler et al. (2020-01-01), Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide Front Pharmacol, 11(0):889.
PMID: 32595508
Species: Human
Sample Types: Cell Culture Supernates

B Sadowska et al. (2020-01-01), Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnusrhamnoides (L.) A. Nelson-The Implications for Human Barrier Cells Molecules, 25(9).
PMID: 32397559
Species: Human
Sample Types: Cell Culture Supernates

AER Oliveira et al. (2020-01-01), Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruziï¿½strains unveil a role for fibroblasts in neutrophil recruitment and activation PLoS Pathog., 16(8):e1008781.
PMID: 32810179
Species: Human
Sample Types: Cell Culture Supernates

L Allais et al. (2020-01-01), Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease PLoS ONE, 15(8):e0236657.
PMID: 32760089
Species: Human
Sample Types: Cell Culture Supernates

E Zuccolo et al. (2020-01-01), The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification Int J Mol Sci, 21(12).
PMID: 32585876
Species: Human
Sample Types: Cell Culture Supernates

P Hemström et al. (2020-01-01), Identification and toxicological evaluation of cyclic sulfonium ion degradation products of sulphur mustard Mar. Environ. Res., 162(0):105047.
PMID: 32827946
Species: Human
Sample Types: Cell Culture Supernates

S Ranganatha et al. (2019-01-01), Evaluating S. flexneri pathogenesis in the human enteroid model Infect. Immun., 0(0).
PMID: 30642900
Species: Human
Sample Types: Cell Culture Supernates

M Ferraro et al. (2019-01-01), Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke Exp. Gerontol., 118(0):78-87.
PMID: 30659954
Species: Human
Sample Types: Cell Culture Supernates

D Emal et al. (2019-01-01), Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection Sci Rep, 9(1):106.
PMID: 30643171
Species: Human
Sample Types: Cell Culture Supernates

CR Ojha et al. (2019-01-01), Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes PLoS ONE, 14(2):e0208543.
PMID: 30735502
Species: Human
Sample Types: Cell Culture Supernates

JC Sierra et al. (2019-01-01), ?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30804204
Species: Human
Sample Types: Cell Culture Supernates

C Harris et al. (2019-01-01), An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation J Biomech, 0(0).
PMID: 30922612
Species: Human
Sample Types: Tissue Culture Supernates

RM Ray et al. (2019-01-01), The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations Sci Rep, 9(1):4334.
PMID: 30867477
Species: Human
Sample Types: Cell Culture Supernates

F Abdallah et al. (2019-01-01), R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation Sci Rep, 9(1):4132.
PMID: 30858525
Species: Human
Sample Types: Cell Culture Supernates

S Giuliano et al. (2019-01-01), Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5 Theranostics, 9(4):1181-1199.
PMID: 30867824
Species: Human
Sample Types: Plasma

RD Williamson et al. (2019-01-01), Activation of a TLR9 mediated innate immune response in preeclampsia Sci Rep, 9(1):5920.
PMID: 30976066
Species: Human
Sample Types: Cell Culture Supernates

R Mills et al. (2019-01-01), Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF J Immunol Res, 2019(0):1845128.
PMID: 31098385
Species: Human
Sample Types: Cell Culture Supernates

AK Dickey et al. (2019-01-01), Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei PLoS Negl Trop Dis, 13(5):e0007354.
PMID: 31067234
Species: Human
Sample Types: Cell Culture Supernates

CM Weight et al. (2019-01-01), Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface Nat Commun, 10(1):3060.
PMID: 31311921
Species: Human
Sample Types: Cell Culture Supernates

S Saito et al. (2019-01-01), Ouabain signaling in oral squamous cell carcinoma cells J Oral Sci, 0(0).
PMID: 31548455
Species: Human
Sample Types: Cell Culture Supernates

IJ Yeh et al. (2019-01-01), 6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential Nutrients, 11(10).
PMID: 31569368
Species: Human
Sample Types: Cell Culture Supernates

J Qiao et al. (2019-01-01), Identification of Î±-N-catenin as a novel tumor suppressor in neuroblastoma Oncotarget, 10(49):5028-5040.
PMID: 31489113
Species: Human
Sample Types: Serum

Q Xu et al. (2019-01-01), Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression Aging Cell, 0(0):e13027.
PMID: 31493351
Species: Human
Sample Types: Saliva

S Dogra et al. (2019-01-01), Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults BMC Sports Sci Med Rehabil, 11(0):23.
PMID: 31636910
Species: Human
Sample Types: Cell Culture Supernates

RF Hoffmann et al. (2019-01-01), Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium Sci Rep, 9(1):15047.
PMID: 31636329
Species: Human
Sample Types: Cell Culture Supernates

L Kloss et al. (2019-01-01), ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12 Cell Death Dis, 10(10):760.
PMID: 31591378
Species: Human
Sample Types: Cell Culture Supernates

I Tsilioni et al. (2019-01-01), IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 31591201
Species: Human
Sample Types: Cell Culture Supernates

N Schaunaman et al. (2019-01-01), Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation Infect. Immun., 87(7).
PMID: 31061143
Species: Human
Sample Types: Cell Culture Supernates

SP Pan et al. (2019-01-01), C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling Front Pharmacol, 10(0):1351.
PMID: 31849641
Species: Human
Sample Types: Cell Culture Supernates

J Gimenes-Ju et al. (2019-01-01), FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells Sci Rep, 9(1):18180.
PMID: 31796819
Species: Human
Sample Types: Cell Culture Supernates

J Qi et al. (2019-01-01), Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease Invest. Ophthalmol. Vis. Sci., 60(14):4820-4829.
PMID: 31747682
Species: Human
Sample Types: Cell Culture Supernates

R Riise et al. (2019-01-01), Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes Sci Rep, 9(1):20407.
PMID: 31892708
Species: Human
Sample Types: Cell Culture Supernates

J Knobloch et al. (2019-01-01), LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD J Clin Med, 8(12).
PMID: 31766770
Species: Human
Sample Types: Cell Culture Supernates

P Dimou et al. (2019-01-01), The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis Sci Rep, 9(1):8348.
PMID: 31171837
Species: Human
Sample Types: Cell Culture Supernates

H Fleury et al. (2019-01-01), Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence Nat Commun, 10(1):2556.
PMID: 31186408
Species: Human
Sample Types: Cell Culture Supernates

D Blez et al. (2019-01-01), Ibrutinib induces multiple functional defects in the neutrophil response against Aspergillus fumigatus Haematologica, 0(0).
PMID: 31171644
Species: Human
Sample Types: Cell Culture Supernates

M Paku?a et al. (2019-01-01), A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 11(5).
PMID: 31086083
Species: Human
Sample Types: Cell Culture Supernates

D Zhang et al. (2018-01-01), Analysis of the association between Fc receptor family gene polymorphisms and ocular Behï¿½et's disease in Han Chinese Sci Rep, 8(1):4850.
PMID: 29555961
Species: Human
Sample Types: Cell Culture Supernates

JA Fraser et al. (2018-01-01), Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations Sci Rep, 8(1):7506.
PMID: 29760395
Species: Human
Sample Types: Whole Blood

JB Herrmann et al. (2018-01-01), Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.ï¿½meningitidis Sepsis and Is a Potential Target for Disease Treatment MBio, 9(1).
PMID: 29362231
Species: Human
Sample Types: Cell Culture Supernates

RA Mubarak et al. (2018-01-01), Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages Respir. Res., 19(1):126.
PMID: 29940963
Species: Human
Sample Types: Cell Culture Supernates

D Tör?csik et al. (2018-01-01), Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands PLoS ONE, 13(6):e0198323.
PMID: 29927962
Species: Human
Sample Types: Tears

A Micera et al. (2018-01-01), Age-Related Changes to Human Tear Composition Invest. Ophthalmol. Vis. Sci., 59(5):2024-2031.
PMID: 29677365
Sample Types: Reference Standard

J Batt et al. (2018-01-01), TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis Eur Cell Mater, 35(0):13-24.
PMID: 29350745
Species: Human
Sample Types: Cell Culture Supernates

S Di Vincenz et al. (2018-01-01), SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells J. Cell. Mol. Med., 0(0).
PMID: 29411515
Species: Human
Sample Types: Cell Culture Supernates

Y Yue et al. (2018-01-01), Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease Invest. Ophthalmol. Vis. Sci., 59(2):1158-1166.
PMID: 29490353
Species: Human
Sample Types: Cell Culture Supernates

L Tengroth et al. (2018-01-01), Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps Sci Rep, 8(1):1561.
PMID: 29367682
Species: Human
Sample Types: Cell Culture Supernates

I Oikonomidi et al. (2018-01-01), iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE Elife, 7(0).
PMID: 29897333
Species: Human
Sample Types: Cell Culture Supernates

CC Wei et al. (2018-01-01), Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression EBioMedicine, 0(0).
PMID: 29398596
Species: Human
Sample Types: Cell Culture Supernates

CC Díaz Acost et al. (2018-01-01), PGL I expression in live bacteria allows activation of a CD206/PPAR? cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves PLoS Pathog., 14(7):e1007151.
PMID: 29979790
Species: Human
Sample Types: Cell Culture Supernates

AC Gross et al. (2018-01-01), IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis JCI Insight, 3(16).
PMID: 30135299
Species: Human
Sample Types: Cell Culture Supernates

P Daull et al. (2018-01-01), Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles Mol. Vis., 24(0):459-470.
PMID: 30078983
Species: Human
Sample Types: Cell Culture Supernates

B Ku?nar-Kam et al. (2018-01-01), Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells Sci Rep, 8(1):12940.
PMID: 30154415
Species: Human
Sample Types: Cell Culture Supernates

SE Logue et al. (2018-01-01), Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy Nat Commun, 9(1):3267.
PMID: 30111846
Species: Human
Sample Types: Cell Culture Supernates

X Ye et al. (2018-01-01), CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma Oncol Lett, 15(6):9075-9080.
PMID: 29805639
Species: Human
Sample Types: Cell Culture Supernates

T Kubo et al. (2018-01-01), Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma Lab. Invest., 0(0).
PMID: 30254318
Species: Human
Sample Types: Cell Culture Supernates

N Shologu et al. (2018-01-01), Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury Int J Mol Sci, 19(10).
PMID: 30274394
Species: Human
Sample Types: Cell Lysates

L Björkman et al. (2018-01-01), Neutrophil recruitment to inflamed joints can occur without cellular priming J. Leukoc. Biol., 0(0).
PMID: 30570778
Species: Human
Sample Types: Cell Culture Supernates

V Ciancarell et al. (2018-01-01), Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection PLoS Pathog., 14(12):e1007469.
PMID: 30532257
Species: Human
Sample Types: Cell Culture Supernates

F Charbit-He et al. (2018-01-01), Copy number variations and founder effect underlying complete IL-10R? deficiency in Portuguese kindreds PLoS ONE, 13(10):e0205826.
PMID: 30365510
Species: Human
Sample Types: Serum

F Chen et al. (2018-01-01), Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance Nat Commun, 9(1):4315.
PMID: 30333494
Species: Human
Sample Types: Cell Culture Supernates

TM Nordgren et al. (2018-01-01), Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function Toxicol. Sci., 0(0).
PMID: 29319804
Species: Human
Sample Types: Cell Culture Supernates

JW Park et al. (2018-01-01), Rhododendron album Blume extract inhibits TNF-?/IFN-?-induced chemokine production via blockade of NF-?B and JAK/STAT activation in human epidermal keratinocytes Int. J. Mol. Med., 0(0).
PMID: 29532855
Species: Human
Sample Types: Cell Culture Supernates

SR Lea et al. (2018-01-01), The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages Int J Chron Obstruct Pulmon Dis, 13(0):771-780.
PMID: 29535517
Species: Human
Sample Types: Cell Culture Supernates

Z Zeng et al. (2018-01-01), Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD Int J Chron Obstruct Pulmon Dis, 13(0):703-715.
PMID: 29535511
Species: Human
Sample Types: Cell Culture Supernates

DJ Sharkey et al. (2018-01-01), Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 0(0).
PMID: 29596569
Species: Human
Sample Types: Cell Culture Supernates

I Tomašek et al. (2018-01-01), Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface Environ. Pollut., 0(0).
PMID: 29455917
Species: Human
Sample Types: Cell Culture Supernates

F Amjadi et al. (2018-01-01), Variable localization of Toll-like receptors in human fallopian tube epithelial cells Clin Exp Reprod Med, 45(1):1-9.
PMID: 29662819
Species: Human
Sample Types: Cell Culture Supernates

A Burban et al. (2017-01-01), Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways Sci Rep, 7(1):1815.
PMID: 28500348
Species: Human
Sample Types: Cell Culture Supernates

M Tohyama et al. (2017-01-01), Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes Eur. J. Immunol., 0(0).
PMID: 28901004
Species: Human
Sample Types: Serum

CA Castro et al. (2017-01-01), Experimental type 2 diabetes induction reduces serum vaspin, but not serum omentin, in Wistar rats Int J Exp Pathol, 0(0).
PMID: 28444853
Species: Human
Sample Types: Cell Culture Supernates

A Granitzny et al. (2017-01-01), Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study Toxicol Rep, 4(0):89-103.
PMID: 28959630
Species: Human
Sample Types: Cell Culture Supernates

CM Henry et al. (2017-01-01), Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation Mol. Cell, 65(4):715-729.e5.
PMID: 28212752
Species: Human
Sample Types: Cell Culture Supernates

BW Megra et al. (2017-01-01), The Role of Shed PrP(c) in the Neuropathogenesis of HIV Infection J. Immunol., 0(0).
PMID: 28533442
Species: Human
Sample Types: Cell Culture Supernates

KS van der Ge et al. (2017-01-01), Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study Immun Ageing, 14(0):5.
PMID: 28250797
Species: Human
Sample Types: Cell Culture Supernates

Y Hosokawa et al. (2017-01-01), IL-27 Modulates Chemokine Production in TNF-? -Stimulated Human Oral Epithelial Cells Cell. Physiol. Biochem., 43(3):1198-1206.
PMID: 28977795
Species: Human
Sample Types: Amniotic Fluid

SM Lee et al. (2017-01-01), Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes PLoS ONE, 12(3):e0174657.
PMID: 28358839
Species: Human
Sample Types: Cell Culture Supernates

V Selvarani et al. (2017-01-01), Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells Virus Res, 0(0).
PMID: 28279802
Species: Human
Sample Types: Cell Culture Supernates

L Chen et al. (2017-01-01), Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide Sci Rep, 7(0):45172.
PMID: 28345644
Species: Human
Sample Types: Cell Culture Supernates

A Ghosh et al. (2017-01-01), Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression Sci Rep, 7(0):46239.
PMID: 28447619
Species: Human
Sample Types: Cell Culture Supernates

Z Zeng et al. (2017-01-01), Increased expression of Siglec-9 in chronic obstructive pulmonary disease Sci Rep, 7(1):10116.
PMID: 28860481
Species: Human
Sample Types: Cell Culture Supernates

J Miku?a-Pie et al. (2017-01-01), The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors Biomed Res Int, 2017(0):2592496.
PMID: 29085834
Species: Human
Sample Types: Cell Culture Supernates

YA Hayman et al. (2017-01-01), The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration? ERJ Open Res, 3(1).
PMID: 28344981
Species: Human
Sample Types: Amniotic Fluid

JW Park et al. (2017-01-01), Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture PLoS ONE, 12(3):e0173312.
PMID: 28278303
Species: Human
Sample Types: Cell Culture Supernates

L Aubert et al. (2017-01-01), Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine Int J Mol Sci, 18(10).
PMID: 29065466
Species: Human
Sample Types: Cell Culture Supernates

RM Petri et al. (2017-01-01), Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function Stem Cell Reports, 0(0).
PMID: 28781075
Species: Human
Sample Types: Cell Culture Supernates

N Basilico et al. (2017-01-01), Malaria pigment stimulates chemokine production by human microvascular endothelium Acta Trop., 0(0).
PMID: 28476599
Species: Human
Sample Types: Cell Culture Supernates

TJJ Schirris et al. (2017-01-01), Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model Sci Rep, 7(1):10623.
PMID: 28878224
Species: Human
Sample Types: Cell Culture Supernates

AH Bryant et al. (2017-01-01), Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors Clin. Exp. Immunol, 0(0).
PMID: 28295207
Species: Human
Sample Types: Cell Culture Supernates

S Janciauski et al. (2017-01-01), Alpha1-antitrypsin binds hemin and prevents oxidative activation of human neutrophils: putative pathophysiological significance J. Leukoc. Biol., 0(0).
PMID: 28716864
Species: Human
Sample Types: Cell Culture Supernates

T Hartwig et al. (2017-01-01), The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2 Mol. Cell, 65(4):730-742.e5.
PMID: 28212753
Species: Human
Sample Types: Amniotic Fluid

EY Jung et al. (2017-01-01), Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less J. Korean Med. Sci, 32(3):480-487.
PMID: 28145652
Species: Human
Sample Types: Cell Culture Supernates

Y Wang et al. (2017-01-01), Chlamydial Lipoproteins Stimulate Toll-Like Receptors 1/2 Mediated Inflammatory Responses through MyD88-Dependent Pathway Front Microbiol, 8(0):78.
PMID: 28184217
Species: Human
Sample Types: Cell Culture Supernates

A Hongo et al. (2017-01-01), The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells Invest. Ophthalmol. Vis. Sci., 58(9):3325-3334.
PMID: 28672399
Species: Human
Sample Types: Cell Culture Supernates

M Mihajlovic et al. (2017-01-01), Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application Sci Rep, 7(1):7103.
PMID: 28769101
Species: Human
Sample Types: Cell Culture Supernates

Lynne A Murray et al. (2017-01-01), Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium. Respiratory Research, 0(0):1465-993X.
PMID: 28468623
Species: Human
Sample Types: Cell Culture Supernates

Puig K et al. (2016-01-01), Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro. PLoS ONE, 10(3):e0119534.
PMID: 25742317
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Engineering a 3D microfluidic culture platform for tumor-treating field application Sci Rep, 6(0):26584.
PMID: 27215466
Species: Human
Sample Types: Cell Culture Supernates

S Robert et al. (2016-01-01), Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells PLoS ONE, 11(4):e0153118.
PMID: 27046197
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma Cell Signal, 28(10):1555-1562.
PMID: 27418099
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin J Immunol, 196(11):4681-91.
PMID: 27183587
Species: Human
Sample Types: Cell Culture Supernates

Brian G Oliver (2016-01-01), A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro Thorax, 71(11):1039-1049.
PMID: 27287090
Species: Bovine
Sample Types: Cell Culture Supernates

S Danesh Mes et al. (2016-01-01), mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages Reprod. Biol. Endocrinol, 14(1):44.
PMID: 27526775
Species: Human
Sample Types: Cell Culture Supernates

Jae Sung Hwang (2016-01-01), Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid Biomol Ther (Seoul), 24(5):529-35.
PMID: 27169822
Species: Human
Sample Types: Cell Culture Supernates

D Jiang et al. (2016-01-01), The Anti-inflammatory Effect of Alpha-1 Antitrypsin in Rhinovirus-infected Human Airway Epithelial Cells J Clin Cell Immunol, 7(6).
PMID: 28191362
Species: Human
Sample Types: Cell Culture Supernates

M Zheng et al. (2016-01-01), Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population Sci Rep, 6(0):24974.
PMID: 27108704
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome PLoS ONE, 11(7):e0158969.
PMID: 27414801
Species: Human
Sample Types: Cell Culture Supernates

Soh Yamamoto (2016-01-01), Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production Biochem. Biophys. Res. Commun, 0(0).
PMID: 27998764
Species: Bovine
Sample Types: Cell Culture Supernates

Healey G et al. (2016-01-01), Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis. J Immunol, 196(2):823-31.
PMID: 26673142
Applications: ChIP

(2016-01-01), Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells Sci Rep, 6(0):32505.
PMID: 27581736
Species: Bovine
Sample Types: Milk

K Piccart et al. (2016-01-01), Local host response following an intramammary challenge with Staphylococcus fleurettii and different strains of Staphylococcus chromogenes in dairy heifers Vet. Res., 47(1):56.
PMID: 27176792
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts Evid Based Complement Alternat Med, 2016(0):5357689.
PMID: 27807462
Species: Human
Sample Types: Serum

Cleriston Farias Queiroz (2016-01-01), Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility J Bras Pneumol, 42(4):241-247.
PMID: 27832230
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma Respir. Res., 17(1):153.
PMID: 27852250
Species: Human
Sample Types: Cell Culture Supernates

Ines Tomašek (2016-01-01), Combined exposure of diesel exhaust particles and respirable Soufriï¿½re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model Part Fibre Toxicol, 13(1):67.
PMID: 27955700
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium J Immunol, 0(0).
PMID: 27534549
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages Infect Immun, 0(0).
PMID: 27481240
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils J Immunol, 196(5):2319-26.
PMID: 26800872
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating J Control Release, 0(0).
PMID: 27686581
Species: Human
Sample Types: Cell Culture Supernates

Y Koga et al. (2016-01-01), CREB regulates TNF-?-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts Allergol Int, 0(0).
PMID: 27118435
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability Sci Rep, 6(0):39035.
PMID: 27976724
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells PLoS ONE, 11(7):e0154102.
PMID: 27441625
Species: Human
Sample Types: Cell Culture Supernates

Wotschofsky Z et al. (2016-01-01), Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p. PLoS ONE, 11(2):e0148746.
PMID: 26859141
Species: Human
Sample Types: Cell Culture Supernates

Garcia-Ruiz G et al. (2015-01-01), In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta. Reprod Biol Endocrinol, 13(0):115.
PMID: 26446923
Species: Human
Sample Types: Cell Culture Supernates

Fieber C et al. (2015-01-01), Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2. PLoS ONE, 10(3):e0119727.
PMID: 25756897
Species: Human
Sample Types: BALF

Schupp J et al. (2015-01-01), Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis. PLoS ONE, 10(1):e0116775.
PMID: 25590613
Species: Human
Sample Types: Cell Culture Supernates

Gartner M et al. (2015-01-01), Detection and characterisation of Lactobacillus spp. in the bovine uterus and their influence on bovine endometrial epithelial cells in vitro. PLoS ONE, 10(3):e0119793.
PMID: 25803719
Species: Human
Sample Types: Cell Culture Supernates

Kondadi P et al. (2015-01-01), Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response. Vet Res, 46(0):4.
PMID: 25603825
Species: Human
Sample Types: Cell Culture Supernates

Fernandez-Bertolin L et al. (2015-01-01), Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma. PLoS ONE, 10(5):e0125443.
PMID: 25943109
Species: Human
Sample Types: Cell Culture Supernates

Fairclough L et al. (2015-01-01), Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome. Eur J Immunol, 45(10):2937-44.
PMID: 26202849
Species: Human
Sample Types: Cell Culture Supernates

Li H et al. (2015-01-01), Role of hydrogen sulfide in paramyxovirus infections. J Virol, 89(10):5557-68.
PMID: 25740991
Species: Human
Sample Types: Cell Culture Supernates

Perry M et al. (2015-01-01), BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle. J Biol Chem, 290(14):9111-21.
PMID: 25697361
Species: Human
Sample Types: Cell Culture Supernates

Zhou Z et al. (2015-01-01), Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells. PLoS ONE, 10(9):e0138267.
PMID: 26382838
Species: Human
Sample Types: Cell Culture Supernates

Harbort C et al. (2015-01-01), Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis. Blood, 126(26):2842-51.
PMID: 26491069
Species: Human
Sample Types: Whole Cells

Karmakar M et al. (2015-01-01), Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. J Immunol, 194(4):1763-75.
PMID: 25609842
Species: Human
Sample Types: Cell Culture Supernates

Kearney C et al. (2015-01-01), Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production. Cell Death Differ, 22(8):1313-27.
PMID: 25613374
Species: Human
Sample Types: Cell Culture Supernates

Jaguin M et al. (2015-01-01), Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2. PLoS ONE, 10(2):e0116560.
PMID: 25710172
Species: Human
Sample Types: Cell Culture Supernates

Casilag F et al. (2015-01-01), The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition. Infect Immun, 84(1):162-71.
PMID: 26502908
Species: Human
Sample Types: Cell Culture Supernates

Miyamoto J et al. (2015-01-01), A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. J Biol Chem, 290(5):2902-18.
PMID: 25505251
Species: Human
Sample Types: Cell Culture Supernates

Price L et al. (2015-01-01), Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells. Respir Res, 16(0):114.
PMID: 26382031
Species: Human
Sample Types: Cell Culture Supernates

Assirelli E et al. (2014-01-01), Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1beta-stimulated production of chemokines and matrix-degrading enzymes in vitro. PLoS ONE, 9(5):e96925.
PMID: 24819779
Species: Human
Sample Types: Cell Culture Supernates

Reed et al. (2014-01-01), Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors. PLoS ONE, 9(4):e91119.
PMID: 24690886
Species: Human
Sample Types: Cell Culture Supernates

Hutchinson J et al. (2014-01-01), Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways. FASEB J, 28(1):94-105.
PMID: 24076962
Species: Human
Sample Types: Sputum

Balloy V et al. (2014-01-01), Flagellin concentrations in expectorations from cystic fibrosis patients. BMC Pulm Med, 14(0):100.
PMID: 24909229
Species: Human
Sample Types: Cell Culture Supernates

Tanabe T et al. (2014-01-01), IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells. Clin Exp Allergy, 44(4):540-52.
PMID: 24479526
Species: Bovine
Sample Types: Cell Culture Supernates

Turner M et al. (2014-01-01), Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6. Endocrinology, 155(4):1453-65.
PMID: 24437488
Species: Human
Sample Types: Cell Culture Supernates

Robciuc A et al. (2014-01-01), Lipid-modifying enzymes in human tear fluid and corneal epithelial stress response. Invest Ophthalmol Vis Sci, 55(1):16-24.
PMID: 24302584
Species: Human
Sample Types: Sputum

Green B et al. (2014-01-01), Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma. PLoS ONE, 9(6):e100645.
PMID: 24955983
Species: Human
Sample Types: Cell Culture Supernates

Perry et al. (2014-01-01), Role of non-coding RNAs in maintaining primary airway smooth muscle cells. Respir Res, 15(0):58.
PMID: 24886442
Species: Human
Sample Types: Cell Culture Supernates

Comer D et al. (2014-01-01), Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells. BMC Pulm Med, 14(0):32.
PMID: 24581246
Species: Human
Sample Types: Tissue Secretion

Rechenberg D et al. (2014-01-01), Periapical fluid RANKL and IL-8 are differentially regulated in pulpitis and apical periodontitis. Cytokine, 69(1):116-9.
PMID: 25022970
Species: Human
Sample Types: Cell Culture Supernates

O'Sullivan M et al. (2014-01-01), Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells. PLoS ONE, 9(4):e95566.
PMID: 24743449
Species: Human
Sample Types: Cell Culture Supernates

Chen et al. (2014-01-01), Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer. PLoS ONE, 9(4):e96177.
PMID: 24781445
Species: Human
Sample Types: Cell Culture Supernates

Zhang Q et al. (2014-01-01), A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis. PLoS ONE, 9(5):e96943.
PMID: 24816862
Species: Human
Sample Types: Cell Culture Supernates

Al-Kuhlani M et al. (2014-01-01), TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans. PLoS ONE, 9(4):e93939.
PMID: 24695582
Species: Human
Sample Types: Cell Culture Supernates

Hanuszkiewicz A et al. (2014-01-01), Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses. J Biol Chem, 289(27):19231-44.
PMID: 24841205
Species: Human
Sample Types: Cell Culture Supernates

Seeger P et al. (2014-01-01), Activin A as a mediator of NK-dendritic cell functional interactions. J Immunol, 192(3):1241-8.
PMID: 24395917
Species: Human
Sample Types: Cell Culture Supernates

Doble et al. (2014-01-01), IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others? J Invest Dermatol, 134(3):852-5.
PMID: 24056860
Species: Human
Sample Types: Cell Culture Supernates

Shah S et al. (2014-01-01), Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone. J Biol Chem, 289(19):13667-79.
PMID: 24692548
Species: Human
Sample Types: Cell Culture Supernates

Cohen-Kedar S et al. (2014-01-01), Human intestinal epithelial cells respond to beta-glucans via Dectin-1 and Syk. Eur J Immunol, 44(12):3729-40.
PMID: 25251945
Species: Human
Sample Types: Cell Culture Supernates

Miyazaki Y et al. (2014-01-01), Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling. PLoS ONE, 9(11):e112770.
PMID: 25415295
Labrousse D et al. (2014-01-01), Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection. PLoS ONE, 9(6):e97546.
PMID: 24905099
Species: Human
Sample Types: Cell Culture Supernates

Dreymueller D et al. (2014-01-01), Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes. J Immunol, 192(2):722-31.
PMID: 24342803
Species: Human
Sample Types: Cell Culture Supernates

Long H et al. (2014-01-01), The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function. PLoS ONE, 9(4):e93550.
PMID: 24695807
Species: Human
Sample Types: Cell Culture Supernates

Cheng K et al. (2014-01-01), CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Br J Haematol, 165(1):134-44.
PMID: 24428589
Species: Human
Sample Types: Cell Culture Supernates

Lin F et al. (2014-01-01), Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats. PLoS ONE, 9(7):e102450.
PMID: 25058444
Species: Human
Sample Types: Cell Culture Supernates

Xiang Q et al. (2014-01-01), TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study. PLoS ONE, 9(1):e84214.
PMID: 24416204
Species: Human
Sample Types: Cell Culture Supernates

Herath T et al. (2013-01-01), Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts. PLoS ONE, 8(3):e58496.
PMID: 23554896
Species: Human
Sample Types: Cell Culture Supernates

Wallace A et al. (2013-01-01), Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia. Am J Pathol, 183(6):1853-61.
PMID: 24103555
Species: Human
Sample Types: Serum

Punsmann S et al. (2013-01-01), Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. PLoS ONE, 8(12):e82734.
PMID: 24340055
Species: Human
Sample Types: Epithelial Fluid

Kumakura S et al. (2013-01-01), Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol. Mol Med Rep, 8(6):1643-8.
PMID: 24145706
Species: Human
Sample Types: Cell Culture Supernates

Hakim A et al. (2013-01-01), Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity. FASEB J, 27(11):4510-9.
PMID: 23934279
Species: Human
Sample Types: Cell Culture Supernates

Dabirian S et al. (2013-01-01), Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate. PLoS Negl Trop Dis, 7(10):e2491.
PMID: 24147170
Species: Human
Sample Types: Cell Culture Supernates

Shamis Y et al. (2013-01-01), Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS ONE, 8(12):e83755.
PMID: 24386271
Species: Human
Sample Types: Cell Culture Supernates

Ding C et al. (2013-01-01), 1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes. PLoS ONE, 8(4):e61707.
PMID: 23637889
Species: Human
Sample Types: Cell Culture Supernates

Goretti E et al. (2013-01-01), MicroRNA-16 affects key functions of human endothelial progenitor cells. J Leukoc Biol, 93(5):645-55.
PMID: 23325924
Species: Human
Sample Types: Cell Culture Supernates

Jeffery H et al. (2013-01-01), Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells. J Virol, 87(11):6530-5.
PMID: 23536673
Species: Human
Sample Types: Cell Culture Supernates

Parola C et al. (2013-01-01), Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway. PLoS ONE, 8(12):e82867.
PMID: 24386121
Chung Y et al. (2013-01-01), S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A. PLoS ONE, 8(4):e62372.
PMID: 23638054
Species: N/A
Sample Types: Cell Culture Supernates

Belibasakis G et al. (2013-01-01), Interleukin-8 responses of multi-layer gingival epithelia to subgingival biofilms: role of the "red complex" species. PLoS ONE, 8(12):e81581.
PMID: 24339946
Species: Human
Sample Types: Cell Culture Supernates

Moh M et al. (2013-01-01), Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling. FASEB J, 27(8):2957-66.
PMID: 23620528
Species: Human
Sample Types: Cell Culture Supernates

Jitprasertwong P et al. (2013-01-01), Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1. Cytokine, 65(2):222-30.
PMID: 24275551
Species: Human
Sample Types: Cell Culture Supernates

Kachroo P et al. (2013-01-01), IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. J Exp Clin Cancer Res, 32(0):97.
PMID: 24274066
Species: Human
Sample Types: Cell Culture Supernates

Houser J et al. (2013-01-01), A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity. PLoS ONE, 8(12):e83077.
PMID: 24340081
Species: Human
Sample Types: Cell Culture Supernates

Henrick BM et al. (2012-01-01), Milk Matters: Soluble Toll-Like Receptor 2 (sTLR2) in Breast Milk Significantly Inhibits HIV-1 Infection and Inflammation. PLoS ONE, 7(7):e40138.
PMID: 22792230
Species: Human
Sample Types: Cell Culture Supernates

Suh HS et al. (2012-01-01), Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). PLoS ONE, 7(4):e35115.
PMID: 22509390
Species: Human
Sample Types: Cell Culture Supernates

van de Veerdonk FL et al. (2012-01-01), IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. Proc. Natl. Acad. Sci. U.S.A., 109(8):3001-5.
PMID: 22315422
Species: Human
Sample Types: Cell Culture Supernates

Dumitru CA et al. (2012-01-01), A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer. J. Leukoc. Biol., 91(4):591-8.
PMID: 22262799
Species: Human
Sample Types: Cell Culture Supernates

Zhang J et al. (2012-01-01), Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS ONE, 7(4):e34965.
PMID: 22529962
Species: Human
Sample Types: Plasma

(2012-01-01), Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation. Eur J Clin Nutr, 66(9):1072-4.
PMID: 22805498
Species: Human
Sample Types: Cell Culture Supernates

Iram N et al. (2012-01-01), Age-related changes in expression and function of Toll-like receptors in human skin. Development, 139(22):4210-9.
PMID: 23034637
Species: Human
Sample Types: Cell Culture Supernates

Kamekura R et al. (2012-01-01), The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis. Clin. Exp. Allergy, 42(2):218-28.
PMID: 22233535
Species: Human
Sample Types: Cell Culture Supernates

Drannik AG et al. (2012-01-01), Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C. PLoS ONE, 7(4):e35866.
PMID: 22545145
Species: Human
Sample Types: Cell Culture Supernates

Robciuc A et al. (2012-01-01), Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2. J Lipid Res, 53(11):2286-95.
PMID: 22899568
Species: Human
Sample Types: Cell Culture Supernates

Breshears L et al. (2012-01-01), A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1). J Biol Chem, 287(39):32578-87.
PMID: 22833676
Species: Human
Sample Types: Cell Culture Supernates

(2012-01-01), Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. J Neuroinflammation, 9(0):203.
PMID: 22901451
Species: Human
Sample Types: Cell Culture Supernates

Berthelot L et al. (2012-01-01), Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. J. Exp. Med., 209(4):793-806.
PMID: 22451718
Species: Human
Sample Types: Cell Culture Supernates

Vega-Carrascal I et al. (2011-01-01), Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways. J. Immunol., 0(0).
PMID: 21263071
Species: Human
Sample Types: Plasma

Neuenschwander LC et al. (2011-01-01), Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients. Clinics (Sao Paulo), 66(10):1699-705.
PMID: 22012040
Species: Human
Sample Types: Cell Culture Supernates

Kim S et al. (2011-01-01), Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells. Exp. Cell Res., 317(18):2650-60.
PMID: 21925169
Species: Human
Sample Types: Cell Culture Supernates

Marcondes AM et al. (2011-01-01), Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model. Blood, 118(18):5031-9.
PMID: 21900190
Species: Human
Sample Types: Cell Culture Supernates

Rodland EK et al. (2010-01-01), Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis. Infect. Immun., 78(3):1269-75.
PMID: 20008537
Species: Human
Sample Types: Cell Culture Supernates

Ochiel DO et al. (2010-01-01), Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands. J. Leukoc. Biol., 88(3):435-44.
PMID: 20385795
Species: Human
Sample Types: Serum

Reeves EP et al. (2010-01-01), IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. J. Immunol., 184(3):1642-52.
PMID: 20026745
Species: Human
Sample Types: Cell Culture Supernates

Chui JJ et al. (2010-01-01), Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex. Invest. Ophthalmol. Vis. Sci., 51(5):2558-67.
PMID: 20019359
Species: Human
Sample Types: Cell Culture Supernates

Hao Q et al. (2009-01-01), Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. Am. J. Physiol., Cell Physiol., 296(4):C821-7.
PMID: 19176759
Species: Human
Sample Types: Cell Culture Supernates

Tohyama M et al. (2009-01-01), IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur. J. Immunol., 39(10):2779-88.
PMID: 19731362
Species: Human
Sample Types: Serum

Brietzke E et al. (2009-01-01), Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder. Brain Behav. Immun., 23(8):1079-82.
PMID: 19406226
Species: Human
Sample Types: Urine

Hawn TR et al. (2009-01-01), Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS ONE, 4(12):e8300.
PMID: 20016852
Species: Human
Sample Types: Cell Culture Supernates

Wang Q et al. (2009-01-01), Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J. Immunol., 183(11):6989-97.
PMID: 19890046
Species: Human
Sample Types: Cell Culture Supernates

Abolhassani M et al. (2009-01-01), Carbon dioxide inhalation causes pulmonary inflammation. Am. J. Physiol. Lung Cell Mol. Physiol., 296(4):L657-65.
PMID: 19136578
Species: Human
Sample Types: Cell Culture Supernates

Kinoshita H et al. (2009-01-01), Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 123(1):179-86.
PMID: 19056108
Species: Human
Sample Types: Cell Culture Supernates

Eid RE et al. (2009-01-01), Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 119(10):1424-32.
PMID: 19255340
Species: Human
Sample Types: Cell Culture Supernates

Lamhamedi-Cherradi SE et al. (2008-01-01), Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. J. Immunol., 180(9):6000-9.
PMID: 18424720
Species: Human
Sample Types: Cell Culture Supernates

Spadaro M et al. (2008-01-01), Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. FASEB J., 22(8):2747-57.
PMID: 18364398
Species: Human
Sample Types: Cell Culture Supernates

Novitskiy SV et al. (2008-01-01), Adenosine receptors in regulation of dendritic cell differentiation and function. Blood, 112(5):1822-31.
PMID: 18559975
Species: Human
Sample Types: Cell Culture Supernates

Weigert J et al. (2008-01-01), Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes. FEBS Lett., 582(12):1777-82.
PMID: 18442481
Species: Human
Sample Types: Cell Culture Supernates

Lemarie A et al. (2008-01-01), Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway. J. Immunol., 180(9):6010-7.
PMID: 18424721
Species: Human
Sample Types: Cell Culture Supernates

Birrell MA et al. (2008-01-01), Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages. J. Cell. Physiol., 214(1):27-37.
PMID: 17541958
Species: Human
Sample Types: Sputum

McCreanor J et al. (2007-01-01), Respiratory effects of exposure to diesel traffic in persons with asthma. N. Engl. J. Med., 357(23):2348-58.
PMID: 18057337
Species: Human
Sample Types: Cell Culture Supernates

Muselet-Charlier C et al. (2007-01-01), Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling. Biochem. Biophys. Res. Commun., 357(2):402-7.
PMID: 17420005
Species: Guinea Pig
Sample Types: Cell Culture Supernates

Sawant KV et al. (2007-01-01), Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures. Infect. Immun., 75(4):1870-7.
PMID: 17283104
Species: Human
Sample Types: Cell Culture Supernates

Hung LC et al. (2007-01-01), A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways. Biochem. Pharmacol., 73(12):1957-70.
PMID: 17445776
Species: Human
Sample Types: Cell Culture Supernates

Weindl G et al. (2007-01-01), Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J. Clin. Invest., 117(12):3664-3672.
PMID: 17992260
Species: Human
Sample Types: Cell Culture Supernates

Birrell MA et al. (2007-01-01), Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses. J. Biol. Chem., 282(44):31882-90.
PMID: 17766241
Species: Human
Sample Types: Cell Culture Supernates

Sa SM et al. (2007-01-01), The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol., 178(4):2229-40.
PMID: 17277128
Species: Human
Sample Types: BALF

Hilliard TN et al. (2007-01-01), Airway remodelling in children with cystic fibrosis. Thorax, 62(12):1074-80.
PMID: 17526676
Species: Human
Sample Types: Cell Culture Supernates

Yang SR et al. (2007-01-01), Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am. J. Physiol. Lung Cell Mol. Physiol., 292(2):L567-76.
PMID: 17041012
Species: Human
Sample Types: Cell Culture Supernates

Potapova IA et al. (2007-01-01), Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro. Stem Cells, 25(7):1761-8.
PMID: 17395769
Species: Human
Sample Types: Cell Culture Supernates

Yamasaki K et al. (2007-01-01), Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat. Med., 13(8):975-80.
PMID: 17676051
Species: Human
Sample Types: Tracheal Lavage Fluid

Bourbia A et al. (2006-01-01), NF-kappaB in tracheal lavage fluid from intubated premature infants: association with inflammation, oxygen, and outcome. Arch. Dis. Child. Fetal Neonatal Ed., 91(1):F36-9.
PMID: 16049063
Species: Human
Sample Types: Cell Culture Supernates

Birrell MA et al. (2006-01-01), Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease. J. Pharmacol. Exp. Ther., 318(2):741-50.
PMID: 16690722
Species: Human
Sample Types: Cell Culture Supernates

LeBouder E et al. (2006-01-01), Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk. J. Immunol., 176(6):3742-52.
PMID: 16517743
Species: Guinea Pig
Sample Types: Cell Culture Supernates

Tree JA et al. (2006-01-01), Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination. Infect. Immun., 74(2):1436-41.
PMID: 16428800
Species: Human
Sample Types: Cell Culture Supernates

Sukkar MB et al. (2006-01-01), Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle. J. Allergy Clin. Immunol., 118(3):641-8.
PMID: 16950283
Species: Human
Sample Types: Cell Culture Supernates

Fritz JH et al. (2005-01-01), Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur. J. Immunol., 35(8):2459-70.
PMID: 16021602
Species: Human
Sample Types: Cell Culture Supernates

Miranda-Carus ME et al. (2004-01-01), IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J. Immunol., 173(2):1463-76.
PMID: 15240743
Species: Human
Sample Types: Cell Culture Supernates

Oynebraten I et al. (2004-01-01), Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood, 104(2):314-20.
PMID: 15044249
Species: Human
Sample Types: Urine

Kumar A et al. (2002-01-01), Urinary interleukin-8 predicts the response of standard and low dose intravesical bacillus Calmette-Guerin (modified Danish 1331 strain) for superficial bladder cancer. J. Urol., 168(5):2232-5.
PMID: 12394765
Species: Guinea Pig
Sample Types: Cell Culture Supernates

Lyons MJ et al. (2002-01-01), Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosis. Infect. Immun., 70(10):5471-8.
PMID: 12228272
Species: Human
Sample Types: Cell Culture Supernates

Bellini A et al. (), Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immuno5(2):140-9.
PMID: 22189956
Species: Human
Sample Types: Cell Culture Supernates

LeBouder E et al. (), Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk. J Immuno171(12):6680-9.
PMID: 14662871
Species: Human
Sample Types: Cell Culture Supernates

Patel A et al. (), Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells. J Pharmacol Exp The361(3):462-471.
PMID: 28404689

There are no citations that match your criteria.

Showing 1 - 10 of 388 citations Showing All

Customer Reviews for Human IL-8/CXCL8 DuoSet ELISA (21)

4.7 out of 5

21 customer ratings

5 stars

76%

4 stars

19%

3 stars

2 stars

1 star

Customer Images

(16)

See all customer images

Showing 1 - 5 of 21 reviews Showing All

Filter By:

Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Plasma

Verified Customer | Posted 12/13/2021

Good results in plasma. Used neat and 1:5.
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum-free Cell Culture Supernates

Verified Customer | Posted 11/30/2021
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/29/2021
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 01/27/2021
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Primary airway epithelial cells

Verified Customer | Posted 05/01/2020
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum and Plasma

Verified Customer | Posted 04/02/2020

We used this kit for the quantification of IL-8 in human serum and plasma. We could not see any signals. Nevertheless, well-explained protocol.
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell Culture Media

Verified Customer | Posted 01/25/2020
Human IL-8/CXCL8 DuoSet ELISA

Name: sothy yi

Sample Tested: human whole blood

Verified Customer | Posted 12/11/2019
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: HUVEC human umbilical vein endothelial cells

Verified Customer | Posted 09/14/2019

Total Cell Protein
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant,Stimulated Human Bronchial Epithelial Cell Line (BEAS-2B)

Verified Customer | Posted 09/07/2019
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Tissue Culture Media

Verified Customer | Posted 08/01/2019
Human IL-8/CXCL8 DuoSet ELISA

Name: Sophie Millar

Sample Tested: Cell Culture Media

Verified Customer | Posted 01/16/2019
Human IL-8/CXCL8 DuoSet ELISA

Name: Ivan Luzardo

Sample Tested: Cell Lysates

Verified Customer | Posted 01/03/2019
Human IL-8/CXCL8 DuoSet ELISA

Name: Leslie Priddy

Sample Tested: Serum

Verified Customer | Posted 03/30/2018
Human IL-8/CXCL8 DuoSet ELISA

Name: Balaji Mahender

Sample Tested: Citrate Plasma,EDTA Plasma,Heparin Plasma

Verified Customer | Posted 01/18/2018
Human IL-8/CXCL8 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum and Plasma

Verified Customer | Posted 08/02/2017
Human CXCL8/IL-8 DuoSet ELISA

Name: Anonymous

Sample Tested: HUVEC human umbilical vein endothelial cells

Verified Customer | Posted 08/19/2016
Human CXCL8/IL-8 DuoSet ELISA

Name: sothy yi

Sample Tested: THP-1 human acute monocytic leukemia cell line

Verified Customer | Posted 08/02/2016
Human CXCL8/IL-8 DuoSet ELISA

Name: Anonymous

Sample Tested: HUVEC human umbilical vein endothelial cells

Verified Customer | Posted 06/02/2016

Very nice IL8 detection in HUVEC cells treated with pro-inflammatory stimuli. Slightly higher background in untreated cells than expected, but not overly problematic. Would definitely publish and use again.
Human CXCL8/IL-8 DuoSet ELISA

Name: Yu Sun

Sample Tested: Human cell conditioned medium

Verified Customer | Posted 05/24/2016
Human CXCL8/IL-8 DuoSet ELISA, 15 Plate

Name: Yanhan Wang

Sample Tested: NHEK human normal epidermal keratinocytes

Verified Customer | Posted 02/25/2016

There are no reviews that match your criteria.

Showing 1 - 5 of 21 reviews Showing All

FAQs for Human IL-8/CXCL8 DuoSet ELISA

Is PBS a suitable alternative with which to formulate the Reagent Diluent?

Our lab has determined that Tris-buffered saline generates optimal assay performance in comparison to PBS for this assay. This assay is validated with Reagent Diluent formulated using Tris-buffered saline.

Human IL-8/CXCL8 DuoSet ELISA

R&D Systems, Inc. a Bio-Techne Brand

Key Product Details

Customers also Viewed

Customers also Purchased

Summary for Human IL-8/CXCL8 DuoSet ELISA

Product Specifications for Human IL-8/CXCL8 DuoSet ELISA

Kit Contents for Human IL-8/CXCL8 DuoSet ELISA

Other Reagents Required

Scientific Data Examples for Human IL-8/CXCL8 DuoSet ELISA

Preparation and Storage

Background: IL-8/CXCL8

Citations for Human IL-8/CXCL8 DuoSet ELISA (388)

Customer Reviews for Human IL-8/CXCL8 DuoSet ELISA (21)

Customer Images

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human IL-8/CXCL8 DuoSet ELISA

Human CXCL8/IL-8 DuoSet ELISA

Human CXCL8/IL-8 DuoSet ELISA

Human CXCL8/IL-8 DuoSet ELISA

Human CXCL8/IL-8 DuoSet ELISA

Human CXCL8/IL-8 DuoSet ELISA, 15 Plate

FAQs for Human IL-8/CXCL8 DuoSet ELISA

Product Documents for Human IL-8/CXCL8 DuoSet ELISA

Product Datasheets

COA

Certificate of Analysis

SDS

Bio-Techne Brands