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IL-8/CXCL8 Products

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

69 results for "IL-8/CXCL8" in Products

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IL-8/CXCL8 Products

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.

69 results for "IL-8/CXCL8" in Products

Simple Plex 16x4 Panel including IL-1b/IL-1F2,IL-6 2nd gen,IL-8,and TNF-a 2nd gen

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

ELISA

Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

WB, Simple Western, CyTOF-ready, ICC, ICFlow, Neut

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Catalog #: 894950

Control for use with Human IL-8/CXCL8 Simple Plex Cartridge Kit

Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies

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