Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Human IL-8/CXCL8 Quantikine ELISA Kit
Brand: R&D Systems
SKU: D8000C
Rating: 5 (11 reviews)

R&D Systems, Inc. a Bio-Techne Brand

Catalog # D8000C

Citations (409)

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Key Product Details

Assay Length:	3.5 hours
Sample Type & Volume Required Per Well:	Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Citrate Plasma (50 uL)
Sample Types:	Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Sensitivity:	7.5 pg/mL
Assay Range:	31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Human IL-8/CXCL8 Quantikine ELISA Kit Summary:	The Quantikine Human IL-8 Immunoassay is a 3.5 hour solid phase ELISA designed to measure human IL-8 in cell culture supernates, serum, and plasma. It is based on antibodies raised against the 72 aa variant of human IL-8 derived from E. coli. It is calibrated with the same recombinant factor. This immunoassay accurately quantitates recombinant human IL-8. Measurement of natural human IL-8 or the 77 aa variant of human IL-8 gave results parallel to the standard curves obtained using the E. coli-expressed Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-8.

View Full Technical Details for Human IL-8/CXCL8 Quantikine ELISA Kit

Product Specifications for Human IL-8/CXCL8 Quantikine ELISA Kit

Assay Type	Solid Phase Sandwich ELISA
Format	96-well strip plate
Measurement	Quantitative ELISA
Detection Method	Colorimetric - 450nm (TMB)
Conjugate	HRP
Reactivity	Human
Specificity	Natural and recombinant human IL-8
Cross-reactivity	< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference	No significant interference observed with available related molecules.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision

Inter-Assay Precision (Precision between assays) hree samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	115	386	802	132	410	817
Standard Deviation	5.3	17	37.9	10.7	28	42.4
CV%	4.6	4.4	4.7	8.1	6.8	5.2

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	168	526	1093	196	581	1160
Standard Deviation	9.4	28.6	70.7	14.5	56.6	70.2
CV%	5.6	5.4	6.5	7.4	9.7	6.1

Recovery

The recovery of IL-8 spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type	Average % Recovery	Range %
Cell Culture Media (n=5)	98	85-114
Citrate Plasma (n=5)	105	95-114
EDTA Plasma (n=5)	103	97-111
Heparin Plasma (n=5)	102	92-107
Serum (n=5)	98	88-106

Linearity

To assess the linearity of the assay, samples were spiked with high concentrations of IL-8 in various matrices and diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.

Scientific Data Examples for Human IL-8/CXCL8 Quantikine ELISA Kit

	Human CXCL8 ELISA/IL-8 ELISA Cell Culture Supernate Standard Curve
	Human CXCL8 ELISA/IL-8 ELISA Serum/Plasma Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-8/CXCL8

Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent.

Multiple isoforms of IL-8 are generated through both alternative splicing and differential proteolytic cleavage. In humans, alternative splicing generates an iso-form with an eleven aa substitution at the C-terminus. Proteolytic processing results in N-terminal truncation of IL-8 and is likely a cell-specific event. For example, fibroblasts and endothelial cells generate the 1-77 form by cleaving IL-8 following Glu21, while monocytes and lymphocytes generate the 6-77 form by cleaving following Leu25. These truncated forms generally show increased bioactivity, particularly through the CXCR1 receptor. IL-8 can also undergo citrullination on Arg27 of the precursor, a modification that increases its half-life and ability to induce leukocytosis. A wide variety of cells secrete IL-8 including monocytes and neutrophils, fibroblasts and keratinocytes, mast cells, visceral smooth muscle cells, dendritic cells, type II great alveolar cells, and endothelial cells.

IL-8 bioactivity is mediated through two G-protein-coupled receptors, termed CXCR1/IL-8 RA and CXCR2/IL-8 RB. CXCR1 is 45-50 kDa in size and is used almost exclusively by IL-8. CXCR2 is 35-40 kDa in size and is used by nearly all CXC chemokines. Both CXCR1 and CXCR2 constitutively associate into functional homodimers. They can also heterodimerize, but these complexes dissociate following IL-8 binding. CXCR2 responds to low concentrations of IL-8 and is principally associated with chemotaxis and MMP-9 release. CXCR1, in contrast, responds to high concentrations of IL-8 and is associated with respiratory burst and phospholipase D2 activation. Thus, CXCR2 ligation induces leukocyte adhesion to activated vascular endothelium and migration to sites of inflammation, while CXCR1 ligation primes neutrophil antimicrobial activity. IL-8 can also form a complex with Serpin A1/alpha-1 Antitrypsin, and this prevents IL-8 interaction with CXCR1.

In addition to its pro-inflammatory effects, IL-8 is involved in angiogenesis and the pathogenesis of atherosclerosis and cancer. It induces VEGF expression in vascular endothelial cells and functions as an autocrine factor for EC growth and angiogenesis. It is upregulated in atherosclerotic lesions and is elevated in the serum and cerebrospinal fluid following myocardial infarction. In cancer, IL-8 promotes epithelial-mesenchymal transition as well as tumor cell invasiveness and metastasis.

Item	Value
Long Name	Interleukin 8
Entrez Gene IDs	3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names	3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP-1TSG-1, GCP1, IL-8, IL8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, MONAP, MONAPGCP1, NAF, NAP-1NAP1, NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1, interleukin 8, member 8

Citations for Human IL-8/CXCL8 Quantikine ELISA Kit (409)

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Citations are publications that use Bio-Techne products. Selected citations for Human IL-8/CXCL8 Quantikine ELISA Kit include:

Species: Human
Sample Types: Cell Culture Supernates

K Li et al. (2023-01-01), Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models Journal of Orthopaedic Translation, 38(0):106-116.
PMID: 36381242
Species: Human
Sample Types: Cell Culture Supernates

A Alshalani et al. (2023-01-01), The impact of biological age of red blood cell on in vitro endothelial activation markers Frontiers in Physiology, 14(0):1127103.
PMID: 36969576
Species: Human
Sample Types: Vitreous Humor

T Tsai et al. (2023-01-01), Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy PLoS ONE, 18(1):e0280488.
PMID: 36662891
Species: Human
Sample Types: Cell Culture Supernates

F De Luca et al. (2023-01-01), Identification of ARMH4 and WIPF3 as human podocyte proteins with potential roles in immunomodulation and cytoskeletal dynamics PLoS ONE, 18(1):e0280270.
PMID: 36649229
Species: Human
Sample Types: Cell Culture Supernates

EA Ross et al. (2023-01-01), Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells Nature Communications, 14(1):753.
PMID: 36765065
Species: Human
Sample Types: Cell Culture Supernants

G Ueda et al. (2022-01-01), 10Z?Hymenialdisine inhibits angiogenesis by suppressing NF?kappaB activation in pancreatic cancer cell lines Oncology reports, 47(3).
PMID: 35014682
Species: Human
Sample Types: Cell Culture Supernates

M Smeda et al. (2022-01-01), Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells International Journal of Molecular Sciences, 23(5).
PMID: 35269758
Species: Human
Sample Types: Conditioned Media

HS Kim et al. (2022-01-01), Korean Red Ginseng Extract Inhibits IL-8 Expression via Nrf2 Activation in Helicobacter pylori-Infected Gastric Epithelial Cells Nutrients, 14(5).
PMID: 35268019
Species: Human
Sample Types: Cell Culture Supernates

CL Pouille et al. (2022-01-01), Chicory: Understanding the Effects and Effectors of This Functional Food Nutrients, 14(5).
PMID: 35267932
Species: Human
Sample Types: Cell Culture Supernates

YH Lee et al. (2022-01-01), Chitosan/PVA Hetero-Composite Hydrogel Containing Antimicrobials, Perfluorocarbon Nanoemulsions, and Growth Factor-Loaded Nanoparticles as a Multifunctional Dressing for Diabetic Wound Healing: Synthesis, Characterization, and In Vitro/In Vivo Evaluation Pharmaceutics, 14(3).
PMID: 35335913
Species: Human
Sample Types: Saliva

M Uchida et al. (2022-01-01), A pilot study: the relationship between salivary MCP-1 and IgA, and exercise performance in long-distance runners and sprinters Bmc Research Notes, 15(1):118.
PMID: 35346356
Species: Human
Sample Types: Plasma

ZQ Zhang et al. (2022-01-01), Effect and neural mechanisms of the transcutaneous vagus nerve stimulation for relapse prevention in patients with remitted major depressive disorder: protocol for a longitudinal study BMJ Open, 12(2):e050446.
PMID: 35193903
Species: Human
Sample Types: Plasma

YC Liu et al. (2022-01-01), TGF-beta1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis PLoS ONE, 17(1):e0262074.
PMID: 35061744
Species: Human
Sample Types: Cell Culture Supernates

A Resano et al. (2022-01-01), Elovanoids Counteract Inflammatory Signaling, Autophagy, Endoplasmic Reticulum Stress, and Senescence Gene Programming in Human Nasal Epithelial Cells Exposed to Allergens Pharmaceutics, 14(1).
PMID: 35057008
Species: Human
Sample Types: Serum

DB Rosen et al. (2022-01-01), Cytokine response over the course of COVID-19 infection in pregnant women Cytokine, 154(0):155894.
PMID: 35490452
Species: Human
Sample Types: Cell Culture Supernates

YJ Park et al. (2022-01-01), D-dimer and CoV-2 spike-immune complexes contribute to the production of PGE2 and proinflammatory cytokines in monocytes PloS Pathogens, 18(4):e1010468.
PMID: 35385545
Species: Human
Sample Types: Cell Culture Supernates

JH Shin et al. (2022-01-01), Adipokine human Resistin promotes obesity-associated inflammatory intervertebral disc degeneration via pro-inflammatory cytokine cascade activation Scientific Reports, 12(1):8936.
PMID: 35624126
Species: Human
Sample Types: Cell Culture Supernates

P Montero et al. (2022-01-01), Paclitaxel-Induced Epidermal Alterations: An In Vitro Preclinical Assessment in Primary Keratinocytes and in a 3D Epidermis Model International Journal of Molecular Sciences, 23(3).
PMID: 35163066
Species: Human
Sample Types: Cell Culture Supernates

G Rodionov et al. (2022-01-01), Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo Bone marrow transplantation, 0(0).
PMID: 35538142
Species: Human
Sample Types: Plasma

D Chaar et al. (2022-01-01), Neutrophils and Circulating Inflammatory Biomarkers in Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction The American journal of cardiology, 0(0).
PMID: 35811144
Species: Human
Sample Types: Cell Culture Supernates

AM Mengeste et al. (2022-01-01), Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome Frontiers in Physiology, 13(0):928195.
PMID: 35874526
Species: Human
Sample Types: Cell Culture Supernates

P Hiengrach et al. (2022-01-01), Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice Scientific Reports, 12(1):9345.
PMID: 35661720
Species: Human
Sample Types: Plasma

S Ekstedt et al. (2022-01-01), A prolonged innate systemic immune response in COVID-19 Oncogene, 12(1):9915.
PMID: 35705573
Species: Human
Sample Types: Cell Culture Supernates

C Helissey et al. (2022-01-01), Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium Biology, 11(7).
PMID: 36101361
Species: Human
Sample Types: Cell Culture Supernates

TW Kim et al. (2022-01-01), Microfluidic Electroceuticals Platform for Therapeutic Strategies of Intervertebral Disc Degeneration: Effects of Electrical Stimulation on Human Nucleus Pulposus Cells under Inflammatory Conditions International Journal of Molecular Sciences, 23(17).
PMID: 36077518
Species: Human
Sample Types: Cell Culture Supernates

J Milara et al. (2022-01-01), N-acetylcysteine Reduces Inflammasome Activation Induced by SARS-CoV-2 Proteins In Vitro International Journal of Molecular Sciences, 23(23).
PMID: 36498845
Species: Human
Sample Types: Cell Culture Supernates

FP Veras et al. (2022-01-01), Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation Cell Reports, 41(13):111897.
PMID: 36577385
Species: Human
Sample Types: Plasma

E Kiss et al. (2022-01-01), The Effect of Dietary Methyl-Donor Intake and Other Lifestyle Factors on Cancer Patients in Hungary Cancers, 14(18).
PMID: 36139592
Species: Human
Sample Types: Cell Culture Supernates

R Dinami et al. (2022-01-01), MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer Embo Molecular Medicine, 0(0):e16033.
PMID: 36426578
Species: Rat
Sample Types: BALF

G Costabile et al. (2022-01-01), Boosting Lung Accumulation Of Gallium With Inhalable Nano-Embedded Microparticles For The Treatment Of Bacterial Pneumonia International journal of pharmaceutics, 0(0):122400.
PMID: 36384182
Species: Human
Sample Types: Cell Culture Supernates

S Cadau et al. (2022-01-01), An Inflamed and Infected Reconstructed Human Epidermis to Study Atopic Dermatitis and Skin Care Ingredients International Journal of Molecular Sciences, 23(21).
PMID: 36361668
Species: Human
Sample Types: Cell Culture Supernates

J Wang et al. (2022-01-01), microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells BMC molecular and cell biology, 23(1):60.
PMID: 36564725
Species: Human
Sample Types: Cell Culture Supernates

D Biswas et al. (2021-01-01), LL-37-mediated activation of host receptors is critical for defense against group A streptococcal infection Cell Reports, 34(9):108766.
PMID: 33657368
Species: Human
Sample Types: Cell Culture Supernates

N Komabashir et al. (2021-01-01), Efficacy of chitinase-3-like protein 1 as an inï¿½vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells Regenerative Therapy, 18(0):38-50.
PMID: 33869686
Species: Human
Sample Types: Cell Lysates

ED Bogdan et al. (2021-01-01), IGFBP-3 Mediates Metabolic Homeostasis During Hyperosmolar Stress in the Corneal Epithelium Investigative Ophthalmology Visual Science, 2021;62(7):11.
PMID: 34100890
Species: Human
Sample Types: Cell Culture Supernates

W He et al. (2021-01-01), The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1 PloS Pathogens, 17(3):e1009320.
PMID: 33662035
Species: Rat
Sample Types: Cell Culture Supernates

D Gan et al. (2021-01-01), Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis Frontiers in Pharmacology, 12(0):631891.
PMID: 33746759
Species: Human
Sample Types: Serum

L Avila et al. (2021-01-01), Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 26(0):428-434.
PMID: 33992278
Species: Human
Sample Types: CSF

KY Lee et al. (2021-01-01), Cerebrospinal fluid type I interferon and cytokine profiles in enteroviral meningitis according to the presence or absence of pleocytosis Pediatrics and neonatology, 0(0).
PMID: 33707153
Species: Human
Sample Types: Gingival Crevicular Fluid

P Aleksandro et al. (2021-01-01), Analysis of IL-1&beta, CXCL8, and TNF-&alpha levels in the crevicular fluid of patients with periodontitis or healthy implants BMC Oral Health, 21(1):120.
PMID: 33726736
Species: Human
Sample Types: Plasma

N Kashiwagi et al. (2021-01-01), Granulocyte and monocyte adsorptive apheresis induces apoptosis of neutrophils and release of a novel chemoattractant for desensitization of interleukin-8 response - In vitro and in vivo results Cytokine, 139(0):155410.
PMID: 33395614
Species: Human
Sample Types: Cell Culture Supernates

L Xia et al. (2021-01-01), SHP2 inhibition enhances the anticancer effect of Osimertinib in EGFR T790M mutant lung adenocarcinoma by blocking CXCL8 loop mediated stemness Cancer Cell International, 21(1):337.
PMID: 34217295
Species: Human
Sample Types: Cell Culture Supernates

Q Hou et al. (2021-01-01), Extracellular Hsp90alpha Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer International Journal of Molecular Sciences, 22(14).
PMID: 34299365
Species: Human
Sample Types: Cell Culture Supernates

W Ouyang et al. (2021-01-01), Variable Induction of Pro-Inflammatory Cytokines by Commercial SARS CoV-2 Spike Protein Reagents: Potential Impacts of LPS on In Vitro Modeling and Pathogenic Mechanisms In Vivo International Journal of Molecular Sciences, 22(14).
PMID: 34299155
Species: Human
Sample Types: CSF

Z Fejes et al. (2021-01-01), Preterm Intraventricular Hemorrhage-Induced Inflammatory Response in Human Choroid Plexus Epithelial Cells International Journal of Molecular Sciences, 22(16).
PMID: 34445350
Species: Human
Sample Types: Cell Culture Supernates

AM Montalbano et al. (2021-01-01), Expression/Activation of PAR-1 in Airway Epithelial Cells of COPD Patients: Ex Vivo/In Vitro Study International Journal of Molecular Sciences, 22(19).
PMID: 34639044
Species: Mouse
Sample Types: Serum

A Cheda et al. (2021-01-01), A derivative of vitamin B3 applied several days after exposure reduces lethality of severely irradiated mice Scientific Reports, 11(1):7922.
PMID: 33846380
Species: Human
Sample Types: Serum

E Pawluczuk et al. (2021-01-01), Serum CXCL8 and Its Specific Receptor (CXCR2) in Gastric Cancer Cancers, 13(20).
PMID: 34680333
Species: Human
Sample Types: Cell Culture Supernates

H Gunawardan et al. (2021-01-01), Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 11(1):1949.
PMID: 33479269
Species: Human
Sample Types: Sputum Supernates

J Cheng et al. (2021-01-01), Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms BMC pulmonary medicine, 21(1):284.
PMID: 34488706
Species: Human
Sample Types: Cell Culture Supernates

MR Medapati et al. (2021-01-01), Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells International Journal of Molecular Sciences, 22(18).
PMID: 34576085
Species: Human
Sample Types: Plasma

I Maté et al. (2021-01-01), Accelerated immunosenescence, oxidation and inflammation lead to a higher biological age in COPD patients Experimental gerontology, 154(0):111551.
PMID: 34530106
Species: Human
Sample Types: Plasma

SY Lee et al. (2021-01-01), Plasma BDNF and Cytokines Correlated with Protein Biomarkers for Bipolar II Disorder Journal of personalized medicine, 11(12).
PMID: 34945756
Species: Human
Sample Types: Cell Culture Supernates

HL Wang et al. (2021-01-01), Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo International immunopharmacology, 103(0):107842.
PMID: 34953449
Species: Human
Sample Types: Cell Culture Supernates

G Piatti et al. (2021-01-01), In Vitro Reduction of Interleukin-8 Response to Enterococcus faecalis by Escherichia coli Strains Isolated from the Same Polymicrobial Urines Microorganisms, 9(7).
PMID: 34361936
Species: Human
Sample Types: Cell Culture Supernates

S Sasaki et al. (2021-01-01), Diphenylarsinic acid induced activation of MAP kinases, transcription factors, and oxidative stress-responsive factors and hypersecretion of cytokines in cultured normal human cerebellar astrocytes Neurotoxicology, 88(0):196-207.
PMID: 34883095
Species: Human
Sample Types: Cell Culture Supernates

T Ondee et al. (2021-01-01), Lactiplantibacillus plantarum dfa1 Outperforms Enterococcus faecium dfa1 on Anti-Obesity in High Fat-Induced Obesity Mice Possibly through the Differences in Gut Dysbiosis Attenuation, despite the Similar Anti-Inflammatory Properties Nutrients, 14(1).
PMID: 35010955
Species: Human
Sample Types: Serum

HA Al-Rawaf et al. (2021-01-01), Expression of Circulating MicroRNAs and Myokines and Interactions with Serum Osteopontin in Type 2 Diabetic Patients with Moderate and Poor Glycemic Control: A Biochemical and Molecular Study BioMed Research International, 2021(0):7453000.
PMID: 34917685
Species: Human
Sample Types: Cell Culture Supernates

W Panpetch et al. (2021-01-01), Lactobacillus rhamnosus attenuates Thai chili extracts induced gut inflammation and dysbiosis despite capsaicin bactericidal effect against the probiotics, a possible toxicity of high dose capsaicin PLoS ONE, 16(12):e0261189.
PMID: 34941893
Species: Human
Sample Types: Cell Culture Supernates

KE Hemmings et al. (2021-01-01), Role of MicroRNA-145 in DNA Damage Signalling and Senescence in Vascular Smooth Muscle Cells of Type 2 Diabetic Patients Cells, 10(4).
PMID: 33923614
Species: Human
Sample Types: Cell Culture Supernates

PM Schlievert et al. (2021-01-01), Staphylococcal TSST-1 Association with Eczema Herpeticum in Humans mSphere, 0(0):e0060821.
PMID: 34319127
Species: Human
Sample Types: Cell Culture Supernates

N Sheshadri et al. (2021-01-01), PERK signaling through C/EBPdelta contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells Cell Death Disease, 2021;12(11):1038.
PMID: 34725321
Species: Human
Sample Types: Cell Culture Supernates

SO Mousavi et al. (2021-01-01), Immunological response of fallopian tube epithelial cells to spermatozoa through modulating cytokines and chemokines Journal of reproductive immunology, 146(0):103327.
PMID: 34052728
Species: Mouse
Sample Types: Tissue Homogenates

C Owen-Woods et al. (2020-01-01), Local microvascular leakage promotes trafficking of activated neutrophils to remote organs J. Clin. Invest., 0(0).
PMID: 31971917
Species: Human
Sample Types: Serum

M Sugiyama et al. (2020-01-01), A cross-sectional analysis of clinicopathologic similarities and differences between Henoch-Schï¿½nlein purpura nephritis and IgA nephropathy PLoS ONE, 15(4):e0232194.
PMID: 32324811
Species: Human
Sample Types: cell culture supernatant

PM Witschen et al. (2020-01-01), Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer Cancers (Basel), 12(5).
PMID: 32455980
Species: Human
Sample Types: Saliva

K Babiuch et al. (2020-01-01), Evaluation of Proinflammatory, NF-kappaB Dependent Cytokines: IL-1&alpha, IL-6, IL-8, and TNF-&alpha in Tissue Specimens and Saliva of Patients with Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders J Clin Med, 9(3).
PMID: 32245251
Species: Human
Sample Types: Cell Culture Supernates

J Gorwood et al. (2020-01-01), SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction Cells, 9(4).
PMID: 32244726
Species: Human
Sample Types: Cell Culture Supernates

FA Monsalve et al. (2020-01-01), RID: Evaluation of the Possible Inhibiting Effect of the Proinflammatory Signaling Induced by TNF-&alpha through NF-&kappa&beta and AP-1 in Two Cell Lines of Breast Cancer Mediators Inflamm., 2020(0):2707635.
PMID: 32655311
Species: Human
Sample Types: Cell Supernates

K Furue et al. (2020-01-01), Scratch wound-induced CXCL8 upregulation is EGFR-dependent in keratinocytes J. Dermatol. Sci., 0(0).
PMID: 32690371
Species: Human
Sample Types: Cell Culture Supernates

Z Xu et al. (2020-01-01), Agonism of GPR120 prevented IL-1&beta-induced reduction of extracellular matrix through SOX-9 Aging (Albany NY), 12(12):12074-12085.
PMID: 32580167
Species: Human
Sample Types: Serum

S P?czek et al. (2020-01-01), CXCL-8 in Preoperative Colorectal Cancer Patients: Significance for Diagnosis and Cancer Progression Int J Mol Sci, 21(6).
PMID: 32192002
Species: Human
Sample Types: Cell Culture Lysates

AT Reddy et al. (2020-01-01), Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD) PLoS ONE, 15(2):e0229256.
PMID: 32084204
Species: Human
Sample Types: Cell Culture Supernates

H Li et al. (2020-01-01), A previously identified apoptosis inhibitor iASPP confers resistance to chemotherapeutic drugs by suppressing senescence in cancer cells J. Biol. Chem., 0(0).
PMID: 32005663
Species: Human
Sample Types: Cell Culture Supernates

N Pang et al. (2020-01-01), Endothelial cell?derived CCL15 mediates the transmigration of fibrocytes through the CCL15?CCR1 axis inï¿½vitro Molecular Medicine Reports, 22(6):5339-5347.
PMID: 33174007
Species: Mouse
Sample Types: Cell Culture Supernates

F Cheng et al. (2020-01-01), Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells Drug Design, Development and Therapy, 14(0):5589-5598.
PMID: 33376303
Species: Human
Sample Types: Cell Culture Supernates

A Hackel et al. (2020-01-01), TNF-alpha and IL-1beta sensitize human MSC for IFN-gamma signalling and enhance neutrophil recruitment Eur. J. Immunol., 0(0).
PMID: 32845509
Species: Human
Sample Types: Cell Culture Supernates

C Dugardin et al. (2020-01-01), Explorative Screening of Bioactivities Generated by Plant-Based Proteins after In Vitro Static Gastrointestinal Digestion Nutrients, 12(12).
PMID: 33291464
Species: Human
Sample Types: Cell Culture Supernates

SA Alkandari et al. (2020-01-01), Proteomics of extracellular vesicles produced by Granulicatella adiacens, which causes infective endocarditis PLoS ONE, 15(11):e0227657.
PMID: 33216751
Species: Human
Sample Types: Cell Culture Supernates

L Peng et al. (2020-01-01), Expression of trophoblast derived prostaglandin E2 receptor 2 (EP2) is reduced in patients with recurrent miscarriage and EP2 regulates cell proliferation and expression of inflammatory cytokines J Reprod Immunol, 142(0):103210.
PMID: 33011635
Species: Human
Sample Types: BALF

R Li et al. (2020-01-01), Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury Molecular Medicine Reports, 0(0).
PMID: 32945411
Species: Human
Sample Types: Cell Culture Supernates

T Phillips et al. (2020-01-01), Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa J Dermatol Sci, 0(0).
PMID: 33143962
Species: Human
Sample Types: Serum

MMS Balla et al. (2020-01-01), Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients Transl Oncol, 14(1):100933.
PMID: 33188981
Species: Human
Sample Types: Cell Culture Supernates

VV Edara et al. (2020-01-01), &beta-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes Biomedicines, 8(11).
PMID: 33171974
Species: Human
Sample Types: Plasma

JP Mole et al. (2020-01-01), APOE-&epsilon4-related differences in left thalamic microstructure in cognitively healthy adults Sci Rep, 10(1):19787.
PMID: 33188215
Species: Human
Sample Types: Cell Culture Supernates

A Arcanjo et al. (2020-01-01), The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19) Sci Rep, 10(1):19630.
PMID: 33184506
Species: Human
Sample Types: Cervical Mucus

T Samejima et al. (2020-01-01), Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy J Reprod Immunol, 143(0):103241.
PMID: 33157500
Species: Human
Sample Types: Cell Culture Supernates

X Lv et al. (2020-01-01), The protective effects of memantine against inflammation and impairment of endothelial tube formation induced by oxygen-glucose deprivation/reperfusion Aging (Albany NY), 12(21):21469-21480.
PMID: 33174867
Species: Human
Sample Types: Cell Culture Supernates

YJ Yang et al. (2020-01-01), Probiotics-Containing Yogurt Ingestion and H. pylori Eradication Can Restore Fecal Faecalibacterium prausnitzii Dysbiosis in H. pylori-Infected Children Biomedicines, 8(6).
PMID: 32492860
Species: Human
Sample Types: Cell Culture Supernates

L Cai et al. (2020-01-01), DNA methyltransferase DNMT1 inhibits lipopolysaccharide?induced inflammatory response in human dental pulp cells involving the methylation changes of IL?6 and TRAF6 Mol Med Rep, 21(2):959-968.
PMID: 31974603
Species: Human
Sample Types: Serum

H Kikuchi et al. (2020-01-01), Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome Cancer Res., 0(0).
PMID: 32536602
Species: Human
Sample Types: Cell Culture Supernates

J Venkatesh et al. (2020-01-01), Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKgamma protein enhances the anticancer effect of chemotherapy J. Biol. Chem., 295(11):3532-3552.
PMID: 32024692
Species: Human
Sample Types: Serum

OM Koper-Lenk et al. (2020-01-01), Elevated plasma 20S proteasome chymotrypsin-like activity is correlated with IL-8 levels and associated with an increased risk of death in glial brain tumor patients PLoS ONE, 15(9):e0238406.
PMID: 32886667
Species: Human
Sample Types: Plasma

M Tylicka et al. (2020-01-01), BDNF and IL-8, But Not UCHL-1 and IL-11, Are Markers of Brain Injury in Children Caused by Mild Head Trauma Brain sciences, 10(10).
PMID: 32987792
Species: Human
Sample Types: Complex Sample Type

RG Bhardwaj et al. (2020-01-01), Biofilm growth and IL-8 & TNF-alpha-inducing properties of Candida albicans in the presence of oral gram-positive and gram-negative bacteria BMC Microbiol., 20(1):156.
PMID: 32527216
Species: Human
Sample Types: Cell Culture Supernates

HS Teixeira et al. (2020-01-01), TLR3-Dependent Activation of TLR2 Endogenous Ligands via the MyD88 Signaling Pathway Augments the Innate Immune Response Cells, 9(8).
PMID: 32824595
Species: Human
Sample Types: Plasma

S Xu et al. (2020-01-01), Neonatal hand, foot, and mouth disease due to coxsackievirus A6 in Shanghai BMC Pediatr, 20(1):364.
PMID: 32741368
Species: Human
Sample Types: Cell Culture Supernates

W Panpetch et al. (2019-01-01), Oral Candida administration in a Clostridium difficile mouse model worsens disease severity but is attenuated by Bifidobacterium PLoS ONE, 14(1):e0210798.
PMID: 30645630
Species: Human
Sample Types: Cell Culture Supernates

N Higashino et al. (2019-01-01), Fibroblast activation protein-positive fibroblasts promote tumor progression through secretion of CCL2 and interleukin-6 in esophageal squamous cell carcinoma Lab. Invest., 0(0).
PMID: 30683902
Species: Human
Sample Types: Cell Culture Supernates

YH Chen et al. (2019-01-01), Probiotic Lactobacillus spp. act Against Helicobacter pylori-induced Inflammation J Clin Med, 8(1).
PMID: 30646625
Species: Human
Sample Types: Serum

S Wijetunge et al. (2019-01-01), Association between serum and adipose tissue resistin with dysglycemia in South Asian women Nutr Diabetes, 9(1):5.
PMID: 30778042
Species: Human
Sample Types: Cell Culture Supernates

N Saito et al. (2019-01-01), Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis J. Immunol., 0(0).
PMID: 30692212
Species: Human
Sample Types: Cell Culture Supernates

C Mennan et al. (2019-01-01), A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells Stem Cell Res Ther, 10(1):99.
PMID: 30885254
Species: Human
Sample Types: Cell Culture Supernates

EJ Im et al. (2019-01-01), Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Nat Commun, 10(1):1387.
PMID: 30918259
Species: Human
Sample Types: Cell Culture Supernates

PM Schlievert et al. (2019-01-01), Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines MBio, 10(2).
PMID: 30890614
Species: Human
Sample Types: Cell Culture Supernates

RB Damgaard et al. (2019-01-01), OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death EMBO Mol Med, 11(3).
PMID: 30804083
Species: Human
Sample Types: Cell Culture Supernates

F De Felice et al. (2019-01-01), Sulodexide counteracts endothelial dysfunction induced by metabolic or non-metabolic stresses through activation of the autophagic program Eur Rev Med Pharmacol Sci, 23(6):2669-2680.
PMID: 30964194
Species: Human
Sample Types: Serum

OM Koper-Lenk et al. (2019-01-01), Serum and cerebrospinal fluid Neudesin concentration and Neudesin Quotient as potential circulating biomarkers of a primary brain tumor BMC Cancer, 19(1):319.
PMID: 30953468
Species: Human
Sample Types: Cell Culture Supernates

W Jiang et al. (2019-01-01), Berberine protects immortalized line of human melanocytes from H2O2-induced oxidative stress via activation of Nrf2 and Mitf signaling pathway J. Dermatol. Sci., 0(0).
PMID: 30987854
Species: Human
Sample Types: Plasma

H Flori et al. (2019-01-01), A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome Crit Care, 23(1):128.
PMID: 30995942
Species: Human
Sample Types: Cell Culture Supernates

SJ Park et al. (2019-01-01), Epigenetic downregulation of STAT6 increases HIF-1Î± expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells Acta Neuropathol Commun, 7(1):149.
PMID: 31530290
Species: Human
Sample Types: Cell Culture Supernates

M Wei et al. (2019-01-01), Upregulation of Protease-Activated Receptor 2 Promotes Proliferation and Migration of Human Vascular Smooth Muscle Cells (VSMCs) Med. Sci. Monit., 25(0):8854-8862.
PMID: 31756174
Species: Human
Sample Types: Plasma

HL Lung et al. (2019-01-01), Serum amyloid A1 polymorphisms as risk factors in oesophageal squamous cell carcinoma Hong Kong Med J, 25(5):4-8.
PMID: 31761762
Species: Human
Sample Types: cell culture

S Yuan et al. (2019-01-01), miR-98 Modulates Cytokine Production from Human PBMCs in Systemic Lupus Erythematosus by Targeting IL-6 mRNA J Immunol Res, 2019(0):9827574.
PMID: 31886314
Species: Human
Sample Types: Plasma

Y He et al. (2019-01-01), Inhibition of Triggering Receptor Expressed on Myeloid Cell-1 Alleviates Acute Gouty Inflammation Mediators Inflamm., 2019(0):5647074.
PMID: 31885496
Species: Human
Sample Types: Synovial Fluid

E Bournazou et al. (2019-01-01), Vascular Adhesion Protein-1 (VAP-1) as Predictor of Radiographic Severity in Symptomatic Knee Osteoarthritis in the New York University Cohort Int J Mol Sci, 20(11).
PMID: 31146362
Species: Mouse
Sample Types: Cell Culture Supernates

J Zhao et al. (2019-01-01), Role of PM2.5 in the development and progression of COPD and its mechanisms Respir. Res., 20(1):120.
PMID: 31196090
Species: Human
Sample Types: Cell Culture Supernates

A Romaldini et al. (2019-01-01), Platelet Lysate Inhibits NF-kappaB Activation and Induces Proliferation and an Alert State in Quiescent Human Umbilical Vein Endothelial Cells Retaining Their Differentiation Capability Cells, 8(4).
PMID: 30970613
Species: Human
Sample Types: Cell Culture Supernates

DP Muñoz et al. (2019-01-01), Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging JCI Insight, 5(0).
PMID: 31184599
Species: Human
Sample Types: Cell Culture Supernates

Y Jin et al. (2018-01-01), Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging Sci Rep, 8(1):5145.
PMID: 29572511
Species: Human
Sample Types: Cell Culture Supernates

G Genard et al. (2018-01-01), Proton irradiation orchestrates macrophage reprogramming through NF?B signaling Cell Death Dis, 9(7):728.
PMID: 29950610
Species: Human
Sample Types: Cell Culture Supernates

A Houssaini et al. (2018-01-01), mTOR pathway activation drives lung cell senescence and emphysema JCI Insight, 3(3).
PMID: 29415880
Species: Human
Sample Types: Serum

M Sakuma et al. (2018-01-01), Mobilization of progenitor cells and assessment of vessel healing after second generation drug-eluting stenting by optical coherence tomography Int J Cardiol Heart Vasc, 18(0):17-24.
PMID: 29556525
Species: Human
Sample Types: Cell Culture Supernates

R Tamura et al. (2018-01-01), Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions Oncogenesis, 7(1):4.
PMID: 29358619
Species: Human
Sample Types: Cell Culture Supernates

D Westmeier et al. (2018-01-01), Nanoparticle decoration impacts airborne fungal pathobiology Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 29925597
Species: Human
Sample Types: Cell Culture Supernates

P Makhov et al. (2018-01-01), The convergent roles of NF-?B and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma Cell Death Dis, 9(3):374.
PMID: 29515108
Species: Human
Sample Types: Tissue Homogenates

J Du et al. (2018-01-01), Pre-treatment neutrophil-to-lymphocyte ratio predicts survival in patients with laryngeal cancer Oncol Lett, 15(2):1664-1672.
PMID: 29399193
Species: Human
Sample Types: Cell Culture Supernates

B Chen et al. (2018-01-01), Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells J Cancer, 9(7):1248-1258.
PMID: 29675106
Species: Human
Sample Types: Cell Culture Supernates

Q Guo et al. (2018-01-01), ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer J. Biol. Chem., 0(0).
PMID: 29789423
Species: Human
Sample Types: Serum

S Grygorczuk et al. (2018-01-01), The intrathecal expression and pathogenetic role of Th17 cytokines and CXCR2-binding chemokines in tick-borne encephalitis J Neuroinflammation, 15(1):115.
PMID: 29678185
Species: Human
Sample Types: Cell Culture Supernates

L Du et al. (2018-01-01), CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis Cell Death Dis, 9(7):714.
PMID: 29915309
Species: Human
Sample Types: Cell Culture Supernates

CJ Chen et al. (2018-01-01), ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study Sci Rep, 8(1):3137.
PMID: 29453348
Species: Human
Sample Types: Plasma

L Borges et al. (2018-01-01), Neutrophil Migration and Adhesion Molecule Expression after Acute High-Intensity Street Dance Exercise J Immunol Res, 2018(0):1684013.
PMID: 30069484
Species: Human
Sample Types: Cell Culture Supernates

P Li et al. (2018-01-01), Maelstrom directs myeloid-derived suppressor cells to promote esophageal squamous cell carcinoma progression via activation of the Akt1/RelA/IL-8 signaling pathway Cancer Immunol Res, 0(0).
PMID: 30082413
Species: Human
Sample Types: Cell Culture Supernates

HA Schenkein et al. (2018-01-01), Anticardiolipin (aCL) in sera from periodontitis subjects activate Toll-like receptor 4 (TLR4) PLoS ONE, 13(9):e0203494.
PMID: 30192824
Species: Human
Sample Types: Serum

M Watanabe et al. (2018-01-01), Serum sST2 levels predict severe exacerbation of asthma Respir. Res., 19(1):169.
PMID: 30176857
Species: Human
Sample Types: Plasma

H Alpkvist et al. (2018-01-01), High HMGB1 levels in sputum are related to pneumococcal bacteraemia but not to disease severity in community-acquired pneumonia Sci Rep, 8(1):13428.
PMID: 30194360
Species: Human
Sample Types: Cell Culture Supernates, Whole Tissue

Hiroaki Moroi et al. (2018-01-01), The expression of Toll-like receptor 5 in preterm histologic chorioamnionitis. Journal of Clinical Biochemistry and Nutrition, 0(0):0912-0009.
PMID: 29371755
Species: Human
Sample Types: Cell Culture Supernates

D Son et al. (2018-01-01), Anti-Thermal Skin Aging Activity of Aqueous Extracts Derived from Apple Mint (Mentha suaveolens Ehrh.) in Human Dermal Fibroblasts Evid Based Complement Alternat Med, 2018(0):4595982.
PMID: 30254686
Species: Human
Sample Types: Cell Culture Supernates

S Liu et al. (2018-01-01), A tRNA-derived RNA Fragment Plays an Important Role in the Mechanism of Arsenite -induced Cellular Responses Sci Rep, 8(1):16838.
PMID: 30442959
Species: Human
Sample Types: Cell Culture Supernates

VS Simons et al. (2018-01-01), Comparative Analysis of Peptide Composition and Bioactivity of Different Collagen Hydrolysate Batches on Human Osteoarthritic Synoviocytes Sci Rep, 8(1):17733.
PMID: 30531866
Species: Human
Sample Types: Serum

AE Stanciu et al. (2018-01-01), NT-proBNP and CA 125 levels are associated with increased pro-inflammatory cytokines in coronary sinus serum of patients with chronic heart failure Cytokine, 111(0):13-19.
PMID: 30098475
Species: Human
Sample Types: CSF

P Brenner et al. (2018-01-01), Depression and fatigue in multiple sclerosis: Relation to exposure to violence and cerebrospinal fluid immunomarkers Psychoneuroendocrinology, 89(0):53-58.
PMID: 29324301
Species: Human
Sample Types: Cell Culture Supernates

IWH Jarvis et al. (2018-01-01), Genotoxicity of fine and coarse fraction ambient particulate matter in immortalised normal (TT1) and cancer-derived (A549) alveolar epithelial cells Environ. Mol. Mutagen., 0(0).
PMID: 29368350
Species: Human
Sample Types: Serum
Applications: ELISA Capture

G Jordakieva et al. (2018-01-01), Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects J Occup Med Toxicol, 13(0):5.
PMID: 29434649
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Capture

J Sun et al. (2018-01-01), Suppression of LRRC19 promotes cutaneous wound healing in pressure ulcers in mice Organogenesis, 0(0):1-12.
PMID: 29461900
Species: Human
Sample Types: Cell Culture Supernates

F Pan et al. (2018-01-01), Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice Microbiome, 6(1):54.
PMID: 29562943
Species: Human
Sample Types: Tissue Culture Supernates

C Wyatt Shie et al. (2018-01-01), Encapsulation and controlled release of retinol from silicone particles for topical delivery J Control Release, 0(0).
PMID: 29604311
Species: Human
Sample Types: Serum

O Kofanova et al. (2018-01-01), IL8 and IL16 levels indicate serum and plasma quality Clin. Chem. Lab. Med., 0(0).
PMID: 29425105
Species: Human
Sample Types: Serum

SA Palma-Dura et al. (2018-01-01), Serum levels of advanced glycation end-products (AGEs) and the decoy soluble receptor for AGEs (sRAGE) can discriminate non-alcoholic fatty liver disease in age-, sex- and BMI-matched normo-glycemic adults Metab. Clin. Exp., 0(0).
PMID: 29409822
Species: Human
Sample Types: Cell Culture Supernates

J Gautam et al. (2018-01-01), 4-Hydroxynonenal-induced GPR109A activation elicits bipolar responses, G?i-mediated anti-inflammatory effects, and G??-mediated cell death Br. J. Pharmacol., 0(0).
PMID: 29473951
Species: Human
Sample Types: Cell Culture Supernates

RJW Arts et al. (2018-01-01), BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity Cell Host Microbe, 23(1):89-100.e5.
PMID: 29324233
Species: Human
Sample Types: Cell Culture Supernates

P Nadeau et al. (2018-01-01), Activation of Protease-Activated Receptor 2 leads to impairment of keratinocyte tight junction integrity J. Allergy Clin. Immunol., 0(0).
PMID: 29382595
Species: Human
Sample Types: Cell Culture Supernates

T Goncharov et al. (2018-01-01), Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling Mol. Cell, 69(4):551-565.e7.
PMID: 29452636
Species: Human
Sample Types: Cell Culture Supernates

JL Goralski et al. (2018-01-01), TheIn VitroEffect of Nebulised Hypertonic Saline on Human Bronchial Epithelium Eur. Respir. J., 0(0).
PMID: 29599187
Species: Human
Sample Types: Cell Culture Supernates

B Tian et al. (2017-01-01), Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells Sci Rep, 7(1):2329.
PMID: 28539592
Species: Bovine
Sample Types: Cell Culture Supernates

A Ch Stratak et al. (2017-01-01), The in vitro and ex vivo effect of Auranta 3001 in preventing Cryptosporidium hominis and Cryptosporidium parvum infection Gut Pathog, 9(0):49.
PMID: 28883891
Species: Human
Sample Types: Plasma

A Grzanka et al. (2017-01-01), The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria Allergy Asthma Clin Immunol, 13(0):25.
PMID: 28491102
Species: Human
Sample Types: Cell Culture Supernates

K Biaggini et al. (2017-01-01), Substance P enhances lactic acid and tyramine production in Enterococcus faecalis V583 and promotes its cytotoxic effect on intestinal Caco-2/TC7 cells Gut Pathog, 9(0):20.
PMID: 28439299
Species: Bacteria - Streptococcus pyogenes
Sample Types: Cell Culture Supernates

M Pandey et al. (2017-01-01), Physicochemical characterisation, immunogenicity and protective efficacy of a lead streptococcal vaccine: progress towards Phase I trial Sci Rep, 7(1):13786.
PMID: 29062085
Species: Human
Sample Types: Serum

J Ai et al. (2017-01-01), Preclinical evaluation of SCC244 (Glumetinib), a novel, potent and highly selective inhibitor of c-Met in MET-dependent cancer models Mol. Cancer Ther., 0(0).
PMID: 29237805
Species: Human
Sample Types: Cell Culture Supernates

AA Alangari et al. (2017-01-01), Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies Immun Inflamm Dis, 5(2):190-199.
PMID: 28474502
Species: Human
Sample Types: Cell Culture Supernates

SL Fossum et al. (2017-01-01), Ets Homologous Factor (EHF) has Critical Roles in Epithelial Dysfunction in Airway Disease J. Biol. Chem., 0(0).
PMID: 28461336
Species: Human
Sample Types: Serum

C Tan et al. (2017-01-01), Long-term exposure to high air pollution induces cumulative DNA damages in traffic policemen Sci. Total Environ, 593(0):330-336.
PMID: 28346906
Species: Human
Sample Types: Cell Culture Supernates

S Sakimoto et al. (2017-01-01), CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect JCI Insight, 2(2):e89906.
PMID: 28138561
Species: Human
Sample Types: Serum

Koper O et al. (2017-01-01), Cerebrospinal fluid and serum IL-8, CCL2, and ICAM-1 concentrations in astrocytic brain tumor patients. Ir J Med Sci, 0(0).
PMID: 29086194
Species: Human
Sample Types: Serum

NA Johdi et al. (2017-01-01), Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps Cytokine, 99(0):35-42.
PMID: 28689023
Species: Human
Sample Types: Cell Culture Supernates

RJ Chen et al. (2017-01-01), Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survival Oncotarget, 8(37):62081-62098.
PMID: 28977928
YH Sun et al. (2017-01-01), Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1 Mol Med Rep, 0(0).
PMID: 28560433
Species: Human
Sample Types: Cell Culture Supernates

R Arai et al. (2017-01-01), Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase Mediators Inflamm., 2017(0):3124753.
PMID: 28751819
Species: Human
Sample Types: Cell Culture Supernates

JA Willy et al. (2017-01-01), Function of Inhibitor of Brutons Tyrosine Kinase Isoform ? (IBTK?) in Nonalcoholic Steatohepatitis links Autophagy and the Unfolded Protein Response J. Biol. Chem., 0(0).
PMID: 28710282
Species: Human
Sample Types: Cell Culture Supernates

J Liu et al. (2017-01-01), Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells Exp Ther Med, 13(4):1447-1455.
PMID: 28413491
Species: Human
Sample Types: Milk

B Daniels et al. (2017-01-01), The Effect of Simulated Flash-Heat Pasteurization on Immune Components of Human Milk Nutrients, 9(2).
PMID: 28241418
Species: Human
Sample Types: Cell Culture Supernates

Z Tian et al. (2017-01-01), Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression Sci Rep, 7(0):44405.
PMID: 28337995
Species: Human
Sample Types: Cell Culture Supernates

A Wang et al. (2017-01-01), TWEAK/Fn14 promotes pro-inflammatory cytokine secretion in hepatic stellate cells via NF-?B/STAT3 pathways Mol. Immunol., 87(0):67-75.
PMID: 28411440
Species: Human
Sample Types: Cell Culture Supernates

H Jayatilaka et al. (2017-01-01), Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration Nat Commun, 8(0):15584.
PMID: 28548090
Species: Human
Sample Types: Serum

AW Tolcher et al. (2017-01-01), Phase Ib Study of Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Combination with Pembrolizumab (MK-3475) in Patients with Advanced Solid Tumors Clin. Cancer Res., 0(0).
PMID: 28634283
Species: Human
Sample Types: Vaginal Lavage Fluid

ML Alcaide et al. (2017-01-01), A bio-behavioral intervention to decrease intravaginal practices and bacterial vaginosis among HIV infected Zambian women, a randomized pilot study BMC Infect. Dis., 17(1):338.
PMID: 28494795
Species: Human
Sample Types: Serum

Sofia Avnet (2016-01-01), Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-?B acivation Int. J. Cancer, 0(0).
PMID: 27888521
Species: Human
Sample Types: Tissue Culture Supernates

S Mairpady S et al. (2016-01-01), A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains Sci Rep, 6(0):31360.
PMID: 27511873
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines Onco Targets Ther, 9(0):6485-6498.
PMID: 27799796
Species: Human
Sample Types: Serum

(2016-01-01), Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation PLoS ONE, 11(11):e0165909.
PMID: 27812183
Species: Human
Sample Types: Whole Tissue

Shenyi Jiang (2016-01-01), IL-35 Inhibits Angiogenesis through VEGF/Ang2/Tie2 Pathway in Rheumatoid Arthritis Cell. Physiol. Biochem, 40(5):1105-1116.
PMID: 27960151
Species: Human
Sample Types: Serum

(2016-01-01), Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9 Sci Rep, 6(0):36065.
PMID: 27811960
Species: Human
Sample Types: Cell Culture Supernates

Masako Nakanishi (2016-01-01), Acidic microenvironments induce lymphangiogenesis and IL-8 production via TRPV1 activation in human lymphatic endothelial cells Exp Cell Res, 0(0).
PMID: 27312995
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection PLoS ONE, 11(12):e0168102.
PMID: 27977732
Species: Human
Sample Types: Cell Culture Supernates

Carnicelli D et al. (2016-01-01), The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils. J Immunol, 196(3):1177-85.
PMID: 26695372
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch PLoS ONE, 11(4):e0153387.
PMID: 27128976
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), MicroRNAs regulate cytokine responses in gingival epithelial cells Infect Immun, 0(0).
PMID: 27600506
Species: Human
Sample Types: Urine

Ma?gorzata Pa?czyk-To (2016-01-01), Urine interleukin-6, interleukin-8 and transforming growth factor ?1 in infants with urinary tract infection and asymptomatic bacteriuria Cent Eur J Immunol, 41(3):260-267.
PMID: 27833443
Species: Human
Sample Types: Apical Surface Fluid (ASF)

Thomas H Shaffer (2016-01-01), A Translational Cellular Model to Study the Impact of High Frequency Oscillatory Ventilation (HFOV) on Human Epithelial Cell Function J. Appl. Physiol., 0(0):jap.00400.201.
PMID: 27834669
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), ROS-dependent HMGB1 secretion upregulates IL-8 in upper airway epithelial cells under hypoxic condition Mucosal Immunol, 0(0).
PMID: 27624778
Species: Human
Sample Types: Saliva

Kouji Yamada (2016-01-01), Effect of exercise therapy on cytokine secretion in the saliva of bedridden patients J Phys Ther Sci, 28(10):2871-2876.
PMID: 27821953
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production Sci Rep, 6(0):37367.
PMID: 27869178
Species: Human
Sample Types: Cell Culture Supernates

(2016-01-01), Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system Oncogene, 0(0).
PMID: 27157617
Species: Human
Sample Types: Cell Culture Supernates

Ryu S et al. (2015-01-01), The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes. PLoS ONE, 10(8):e0136887.
PMID: 26309029
Species: Rat
Sample Types: Tissue Culture Supernates

Chuffa L et al. (2015-01-01), Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer. BMC Cancer, 15(0):34.
PMID: 25655081
Species: Human
Sample Types: Plasma

Haghiac M et al. (2015-01-01), Dietary Omega-3 Fatty Acid Supplementation Reduces Inflammation in Obese Pregnant Women: A Randomized Double-Blind Controlled Clinical Trial. PLoS ONE, 10(9):e0137309.
PMID: 26340264
Species: Human
Sample Types: Serum

Wendling D et al. (2015-01-01), Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis. PLoS ONE, 10(3):e0119981.
PMID: 25799392
Species: Human
Sample Types: Cell Culture Supernates

Mohan S et al. (2015-01-01), MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma. Clin Cancer Res, 21(17):3946-56.
PMID: 25977343
Species: Human
Sample Types: Cell Culture Supernates

Osei-Owusu P et al. (2015-01-01), The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses. Infect Immun, 83(4):1507-22.
PMID: 25644012
Species: Human
Sample Types: Whole Blood

Verstraete M et al. (2015-01-01), Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial. Br J Cancer, 112(8):1314-25.
PMID: 25867261
Species: Human
Sample Types: Cell Culture Supernates

Su Y et al. (2015-01-01), The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells. J Immunol, 194(8):3997-4007.
PMID: 25769921
Species: Human
Sample Types: Cell Culture Supernates

Bergenfelz C et al. (2015-01-01), S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival. Br J Cancer, 113(8):1234-43.
PMID: 26448179
Species: Human
Sample Types: Cell Culture Supernates

Sathanoori R et al. (2015-01-01), The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells. PLoS ONE, 10(5):e0125111.
PMID: 25938443
Species: Human
Sample Types: Cell Culture Supernates

Valeri M et al. (2015-01-01), Pathogenic E. coli exploits SslE mucinase activity to translocate through the mucosal barrier and get access to host cells. PLoS ONE, 10(3):e0117486.
PMID: 25789808
Species: Human
Sample Types: Cell Lysates

Stoner T et al. (2015-01-01), Group B streptococcal infection and activation of human astrocytes. PLoS ONE, 10(6):e0128431.
PMID: 26030618
Species: Human
Sample Types: Cell Culture Supernates

Chu H et al. (2015-01-01), CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18. Gene Ther, 22(10):822-9.
PMID: 26043872
Species: Human
Sample Types: Cell Culture Supernates

Marino F et al. (2015-01-01), Production of IL-8, VEGF and Elastase by Circulating and Intraplaque Neutrophils in Patients with Carotid Atherosclerosis. PLoS ONE, 10(4):e0124565.
PMID: 25893670
Species: Human
Sample Types: Cell Culture Supernates

Yang Z et al. (2015-01-01), SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host's NF-kappaB Signalling Activity. PLoS ONE, 10(9):e0138529.
PMID: 26394407
Species: Human
Sample Types: Plasma

Ciortea et al. (2014-01-01), Association between visceral fat, IL-8 and endometrial cancer. Anticancer Res, 34(1):379-83.
PMID: 24403491
Species: Human
Sample Types: Cell Culture Supernates

Gunther J et al. (2014-01-01), Identification of two forms of TNF tolerance in human monocytes: differential inhibition of NF-kappaB/AP-1- and PP1-associated signaling. J Immunol, 192(7):3143-55.
PMID: 24574500
Species: Human
Sample Types: Cell Culture Supernates

Bonfim-Mendonca P et al. (2014-01-01), beta-glucan induces reactive oxygen species production in human neutrophils to improve the killing of Candida albicans and Candida glabrata isolates from vulvovaginal candidiasis. PLoS ONE, 9(9):e107805.
PMID: 25229476
Species: Human
Sample Types: Plasma

Necchi A et al. (2014-01-01), Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy. Br J Cancer, 110(1):26-33.
PMID: 24231947
Species: Human
Sample Types: Cell Culture Supernates

Lin C et al. (2014-01-01), Thrombin-induced CCAAT/enhancer-binding protein beta activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells. J Immunol, 192(1):338-48.
PMID: 24277696
Species: Human
Sample Types: BALF

Chou C et al. (2014-01-01), The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia. BMC Pulm Med, 14(0):182.
PMID: 25409888
Species: Human
Sample Types: Sputum

De Stefano D et al. (2014-01-01), Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy, 10(11):2053-74.
PMID: 25350163
Species: Human
Sample Types: Cell Culture Supernates

Chana K et al. (2014-01-01), Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol, 133(1):207-16.e1-11.
PMID: 24176116
Species: Human
Sample Types: Cell Culture Supernates

Li L et al. (2014-01-01), Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-kappaB and modulation of GR in vivo and in vitro. PLoS ONE, 9(8):e102345.
PMID: 25089961
Species: Human
Sample Types: Cell Culture Supernates

Samuel T et al. (2014-01-01), Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs. BMC Cancer, 14(0):599.
PMID: 25134433
Species: Human
Sample Types: Cell Culture Supernates

Lee S et al. (2014-01-01), Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection. Proc Natl Acad Sci U S A, 111(10):3793-8.
PMID: 24567377
Species: Human
Sample Types: Cell Culture Supernates

Erttmann S et al. (2014-01-01), Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism. PLoS ONE, 9(1):e87859.
PMID: 24498214
Species: Human
Sample Types: Cell Culture Supernates

Welsby I et al. (2014-01-01), PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation. J Biol Chem, 289(38):26642-57.
PMID: 25086041
Species: Human
Sample Types: Cell Culture Supernates

Carstensen M et al. (2014-01-01), Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells. PLoS ONE, 9(1):e85906.
PMID: 24465779
Species: Human
Sample Types: Cell Culture Supernates

Merriman J et al. (2014-01-01), Novel antimicrobial peptides that inhibit gram positive bacterial exotoxin synthesis. PLoS ONE, 9(4):e95661.
PMID: 24748386
Species: Human
Sample Types: Cell Culture Supernates

Chuang T et al. (2014-01-01), miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis. PLoS ONE, 9(4):e95370.
PMID: 24755559
Species: Human
Sample Types: Cell Culture Supernates

Ebeling et al. (2014-01-01), From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract. PLoS ONE, 9(1):e86147.
PMID: 24465925
Species: Human
Sample Types: Cell Culture Supernates

Cerdeira A et al. (2013-01-01), Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors. J Immunol, 190(8):3939-48.
PMID: 23487420
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Sample Types: Cell Culture Supernates

Sawada H et al. (2013-01-01), Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension. J Exp Med, 211(2):263-80.
PMID: 24446489
Species: Human
Sample Types: Cell Culture Supernates

Smrz D et al. (2013-01-01), Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells. Eur J Immunol, 43(7):1873-82.
PMID: 23616175
Species: Bovine
Sample Types: Cell Culture Supernates

Willcocks S et al. (2013-01-01), Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1. J Leukoc Biol, 94(3):449-58.
PMID: 23787127
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Tzeng et al. (2013-01-01), Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid. J Biomed Sci, 20(0):90.
PMID: 24313976
Species: Human
Sample Types: Cell Culture Supernates

Moreno A et al. (2013-01-01), ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene, 33(15):1945-53.
PMID: 23604125
Species: Human
Sample Types: Cell Culture Supernates

Brosnahan A et al. (2013-01-01), Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal epithelial cells through tetramic acids. PLoS ONE, 8(4):e61255.
PMID: 23613823
Species: Human
Sample Types: Feces

Bobo L et al. (2013-01-01), MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation. Infect Immun, 81(3):713-22.
PMID: 23264053
Species: Human
Sample Types: Cell Culture Supernates

Suzuki M et al. (2013-01-01), Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem, 288(15):10684-91.
PMID: 23449982
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Sample Types: Whole Cells

Reidy et al. (2013-01-01), Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection. J Biol Chem, 288(12):8269-78.
PMID: 23372160
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Takeuchi H et al. (2013-01-01), The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-kappaB RelA/p65. PLoS Pathog, 9(4):e1003326.
PMID: 23637609
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Bianchetti L et al. (2012-01-01), IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma. Biochem Biophys Res Commun, 426(1):116-21.
PMID: 22921786
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Zhang Y et al. (2012-01-01), Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. J. Immunol., 188(3):1002-10.
PMID: 22180616
Species: Human
Sample Types: Cell Lysates

Sakitani K et al. (2012-01-01), Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Infect Immun, 80(11):3795-803.
PMID: 22890997
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Gatheral T et al. (2012-01-01), A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses. PLoS ONE, 7(8):e42386.
PMID: 22870324
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Schaefers MM et al. (2012-01-01), Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. PLoS ONE, 7(3):e32813.
PMID: 22431984
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(2012-01-01), Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes. J. Invest. Dermatol., 132(11):2593-600.
PMID: 22673732
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Santhekadur PK et al. (2012-01-01), Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9). J. Biol. Chem., 287(5):3425-32.
PMID: 22167195
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Andersson M et al. (2012-01-01), Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses. Innate Immun, 18(3):531-40.
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Sample Types: Tissue Homogenates

Yamashita-Kashima Y et al. (2012-01-01), Biomarkers for antitumor activity of bevacizumab in gastric cancer models. BMC Cancer, 12(0):37.
PMID: 22273502
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Sample Types: BALF

Quesnel C et al. (2012-01-01), Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Crit. Care Med., 40(1):21-8.
PMID: 21926612
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Paine R et al. (2012-01-01), A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury. Crit. Care Med., 40(1):90-7.
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Dupuy S et al. (2012-01-01), Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 8(1):e1002486.
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Wood LG et al. (2011-01-01), Characterization of innate immune signalling receptors in virus-induced acute asthma. Clin. Exp. Allergy, 41(5):640-8.
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Estrada-Gutierrez G et al. (2011-01-01), Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction. Am. J. Pathol., 178(1):451-60.
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Geraghty P et al. (2011-01-01), TLR4 Protein Contributes to Cigarette Smoke-induced Matrix Metalloproteinase-1 (MMP-1) Expression in Chronic Obstructive Pulmonary Disease. J. Biol. Chem., 286(34):30211-8.
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Desouza CV et al. (2011-01-01), Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction. Diabetes, 60(4):1286-94.
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Kim SG et al. (2011-01-01), Curcumin treatment suppresses IKKbeta kinase activity of salivary cells of patients with head and neck cancer: a pilot study. Clin. Cancer Res., 17(18):5953-61.
PMID: 21821700
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Verma S et al. (2011-01-01), Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. J. Gen. Virol., 92(0):507-15.
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McGuire TR et al. (2011-01-01), Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells. Obesity (Silver Spring), 19(11):2130-6.
PMID: 21901025
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Freund A et al. (2011-01-01), p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J., 30(8):1536-48.
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Xu G et al. (2010-01-01), Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy, 65(5):581-9.
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Yang G et al. (2010-01-01), CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin. Cancer Res., 16(15):3875-86.
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Watanabe T et al. (2010-01-01), NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J. Clin. Invest., 120(5):1645-62.
PMID: 20389019
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Rydkina E et al. (2010-01-01), Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms. Infect. Immun., 78(6):2599-606.
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Sample Types: Plasma

Darmanis S et al. (2010-01-01), Sensitive plasma protein analysis by microparticle-based proximity ligation assays. Mol. Cell Proteomics, 9(2):327-35.
PMID: 19955079
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Brave SR et al. (2010-01-01), Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model. Angiogenesis, 13(4):337-47.
PMID: 20953695
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Gannon PO et al. (2010-01-01), Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer. PLoS ONE, 5(8):e12107.
PMID: 20711410
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Wood LG et al. (2010-01-01), Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma. Clin. Exp. Allergy, 40(2):232-41.
PMID: 19878195
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Koarai A et al. (2010-01-01), Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells. Am. J. Respir. Cell Mol. Biol., 42(6):651-60.
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Tso GH et al. (2010-01-01), Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells. Stem Cells, 28(5):939-54.
PMID: 20222014
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Grant S et al. (2010-01-01), Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model. Eur. J. Pharmacol., 627(1):16-25.
PMID: 19850035
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Sample Types: Serum

Su Y et al. (2010-01-01), A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Clin. Cancer Res., 16(1):348-57.
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Sample Types: Milk

Holmlund U et al. (2010-01-01), Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring. Clin. Exp. Immunol., 162(3):500-9.
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Glynn SA et al. (2010-01-01), Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J. Clin. Invest., 120(11):3843-54.
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Kai-Larsen Y et al. (2010-01-01), Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37. PLoS Pathog., 6(0):e1001010.
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Yagami A et al. (2010-01-01), IL-33 mediates inflammatory responses in human lung tissue cells. J. Immunol., 185(10):5743-50.
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Campeau PM et al. (2009-01-01), Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood, 114(15):3181-90.
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Hardison MT et al. (2009-01-01), The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation. J. Immunol., 182(7):4423-31.
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Semiramoth N et al. (2009-01-01), Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. J. Leukoc. Biol., 85(2):310-21.
PMID: 19015376
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Sample Types: Amniotic Fluid

Dulay AT et al. (2009-01-01), Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection. J. Immunol., 182(11):7244-53.
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Miller M et al. (2009-01-01), Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease. J. Immunol., 182(1):684-91.
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Njau F et al. (2009-01-01), In vitro neutralization of tumor necrosis factor-alpha during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny. FEMS Immunol. Med. Microbiol., 55(2):215-25.
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Connolly-Andersen AM et al. (2009-01-01), Crimean Congo hemorrhagic fever virus infects human monocyte-derived dendritic cells. Virology, 390(2):157-62.
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Rodier F et al. (2009-01-01), Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat. Cell Biol., 11(8):973-9.
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Mizutani K et al. (2009-01-01), Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. J. Cell. Biochem., 106(4):563-9.
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Salim JP et al. (2009-01-01), Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia. Br. J. Haematol., 144(1):69-77.
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Tatara Y et al. (2009-01-01), Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species. J. Mol. Cell. Cardiol., 47(1):104-11.
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Watanabe H et al. (2009-01-01), Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. J. Invest. Dermatol., 129(3):650-6.
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Margulis A et al. (2009-01-01), MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice. Am. J. Physiol. Lung Cell Mol. Physiol., 296(2):L236-47.
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Troseid M et al. (2009-01-01), Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia. Diabetes Care, 32(3):486-92.
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Lee SH et al. (2009-01-01), The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3. J. Immunol., 182(9):5823-35.
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Sandberg WJ et al. (2009-01-01), Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Circ. Res., 104(1):60-8.
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Rudack C et al. (2009-01-01), Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases. J. Immunol., 183(11):7592-601.
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Sun Y et al. (2009-01-01), Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass. Cytokine, 47(3):206-13.
PMID: 19632131
Species: Human
Sample Types: Cell Culture Supernates

Smith AM et al. (2009-01-01), Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J. Exp. Med., 206(9):1883-97.
PMID: 19652016
Species: Human
Sample Types: Cell Culture Supernates

Le Quement C et al. (2008-01-01), MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol., 294(6):L1076-84.
PMID: 18390828
Species: Human
Sample Types: Cell Culture Supernates

Smith C et al. (2008-01-01), High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins. Cardiovasc. Res., 79(1):195-203.
PMID: 18339644
Species: Human
Sample Types: Serum

Zhang Y et al. (2008-01-01), NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Cytokine, 41(2):144-9.
PMID: 18222093
Species: Human
Sample Types: Serum

Hothersall EJ et al. (2008-01-01), Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 63(12):1070-5.
PMID: 18757458
Species: Rabbit
Sample Types: Cell Culture Supernates

Aranha CC et al. (2008-01-01), Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits. Cytokine, 43(1):63-70.
PMID: 18513989
Species: Human
Sample Types: Cell Culture Supernates

Bergin DA et al. (2008-01-01), Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. J. Biol. Chem., 283(46):31736-44.
PMID: 18772136
Species: Human
Sample Types: Sputum

Bayley DL et al. (2008-01-01), Validation of assays for inflammatory mediators in exhaled breath condensate. Eur. Respir. J., 31(5):943-8.
PMID: 18216059
Species: Human
Sample Types: Serum

Lee HL et al. (2008-01-01), Serum and urine levels of interleukin-8 in patients with non-Hodgkin's lymphoma. Cytokine, 43(1):71-5.
PMID: 18502145
Species: Human
Sample Types: Cell Culture Supernates

Maru SV et al. (2008-01-01), Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J. Neuroimmunol., 199(1):35-45.
PMID: 18538864
Species: Human
Sample Types: BALF

Ghio AJ et al. (2008-01-01), Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect. Am. J. Respir. Crit. Care Med., 178(11):1130-8.
PMID: 18723436
Species: Human
Sample Types: Complex Sample Type

Skov L et al. (2008-01-01), IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. J. Immunol., 181(1):669-79.
PMID: 18566434
Species: Human
Sample Types: Cell Culture Supernates

Cherry WB et al. (2008-01-01), A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J. Allergy Clin. Immunol., 121(6):1484-90.
PMID: 18539196
Species: Human
Sample Types: Cell Culture Supernates

Olsnes AM et al. (2008-01-01), In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. J. Interferon Cytokine Res., 28(5):297-310.
PMID: 18547160
Species: Human
Sample Types: Cell Culture Supernates

Siddappa R et al. (2008-01-01), cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo. Proc. Natl. Acad. Sci. U.S.A., 105(20):7281-6.
PMID: 18490653
Species: Human
Sample Types: Sputum

Simpson JL et al. (2007-01-01), Innate immune activation in neutrophilic asthma and bronchiectasis. Thorax, 62(3):211-8.
PMID: 16844729
Species: Human
Sample Types: Cell Culture Supernates

Dame TM et al. (2007-01-01), IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation. J. Immunol., 178(2):1172-9.
PMID: 17202382
Species: Human
Sample Types: Cell Culture Supernates

Zalevsky J et al. (2007-01-01), Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection. J. Immunol., 179(3):1872-83.
PMID: 17641054
Species: Human
Sample Types: Cell Culture Supernates

Gutierrez G et al. (2007-01-01), Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells. Atherosclerosis, 190(1):90-9.
PMID: 16574124
Species: Human
Sample Types: Serum

Coupel S et al. (2007-01-01), Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation. Blood, 109(7):2806-14.
PMID: 17179229
Species: Human
Sample Types: Cell Culture Supernates

Mian MF et al. (2007-01-01), Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J. Leukoc. Biol., 83(3):774-84.
PMID: 18055568
Species: Human
Sample Types: Cell Culture Supernates

Li CJ et al. (2007-01-01), MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. Am. J. Physiol. Lung Cell Mol. Physiol., 292(5):L1297-303.
PMID: 17494953
Species: Human
Sample Types: Plasma

Colla S et al. (2007-01-01), The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis. Blood, 110(13):4464-75.
PMID: 17848618
Species: Human
Sample Types: Cell Culture Supernates

Vidyarani M et al. (2007-01-01), 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine, 40(2):128-34.
PMID: 17911026
Species: Human
Sample Types: Cell Culture Supernates

Lin YL et al. (2007-01-01), Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J. Leukoc. Biol., 82(6):1473-80.
PMID: 17761954
Species: Human
Sample Types: Cell Culture Supernates

Scaldaferri F et al. (2007-01-01), Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J. Clin. Invest., 117(7):1951-60.
PMID: 17557119
Species: Human
Sample Types: Milk

Kverka M et al. (2007-01-01), Cytokine profiling in human colostrum and milk by protein array. Clin. Chem., 53(5):955-62.
PMID: 17363422
Species: Human
Sample Types: Cell Culture Supernates

Abe Y et al. (2007-01-01), L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis, 192(1):56-66.
PMID: 17022986
Species: Human
Sample Types: Cell Culture Supernates

Newcomb DC et al. (2007-01-01), Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression. Am. J. Physiol. Lung Cell Mol. Physiol., 293(4):L1021-8.
PMID: 17631613
Species: Human
Sample Types: Cell Culture Supernates

Lubick K et al. (2007-01-01), Securinine, a GABAA receptor antagonist, enhances macrophage clearance of phase II C. burnetii: comparison with TLR agonists. J. Leukoc. Biol., 82(5):1062-9.
PMID: 17698917
Species: Human
Sample Types: Cell Culture Supernates

Kellouche S et al. (2007-01-01), Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside. Biochem. Biophys. Res. Commun., 363(3):472-8.
PMID: 17888881
Species: Human
Sample Types: Cell Culture Supernates

Neuhoff S et al. (2007-01-01), Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Exp. Hematol., 35(7):1119-31.
PMID: 17588481
Species: Human
Sample Types: Cell Culture Supernates

Ghio AJ et al. (2007-01-01), Lung injury after ozone exposure is iron dependent. Am. J. Physiol. Lung Cell Mol. Physiol., 292(1):L134-43.
PMID: 16905637
Species: Human
Sample Types: BALF

Miller M et al. (2007-01-01), Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J. Allergy Clin. Immunol., 120(5):1118-25.
PMID: 17983873
Species: Human
Sample Types: Serum

Koivisto H et al. (2007-01-01), Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis. Dig. Dis. Sci., 53(2):500-5.
PMID: 17597408
Species: Human
Sample Types: Cell Culture Supernates

Matsuda A et al. (2007-01-01), Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Am. J. Respir. Cell Mol. Biol., 38(2):168-75.
PMID: 17709600
Species: Human
Sample Types: BALF

Perkins GD et al. (2007-01-01), In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury. Thorax, 62(1):36-42.
PMID: 16928710
Species: Human
Sample Types: Urine

Real JM et al. (2007-01-01), Specificity of immunomodulator secretion in urinary samples in response to infection by alpha-hemolysin and CNF1 bearing uropathogenic Escherichia coli. Cytokine, 37(1):22-5.
PMID: 17382555
Species: Human
Sample Types: Tissue Secretion

Gouin JP et al. (2007-01-01), The influence of anger expression on wound healing. Brain Behav. Immun., 22(5):699-708.
PMID: 18078737
Species: Human
Sample Types: Sputum

Simpson JL et al. (2007-01-01), Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am. J. Respir. Crit. Care Med., 177(2):148-55.
PMID: 17947611
Species: Human
Sample Types: Cell Culture Supernates

Tsai WH et al. (2007-01-01), Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells. Crit. Care Med., 35(3):879-85.
PMID: 17235257
Species: Human
Sample Types: Cell Culture Supernates

Martinez de la Torre Y et al. (2007-01-01), Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc. Natl. Acad. Sci. U.S.A., 104(7):2319-24.
PMID: 17283337
Species: Human
Sample Types: Cell Culture Supernates

Bae E et al. (2007-01-01), Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis. Clin. Exp. Immunol., 148(3):410-8.
PMID: 17359498
Behndig AF et al. (2006-01-01), Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans. Eur. Respir. J., 27(2):359-65.
PMID: 16452593
Species: Human
Sample Types: Cell Culture Supernates

Peterson ML et al. (2006-01-01), Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells. Biochemistry, 45(7):2387-97.
PMID: 16475828
Species: Human
Sample Types: Cell Culture Supernates

Wang ZY et al. (2006-01-01), Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways. Exp. Hematol., 34(8):1115-24.
PMID: 16863919
Species: Human
Sample Types: Cell Culture Supernates

Wislez M et al. (2006-01-01), High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res., 66(8):4198-207.
PMID: 16618742
Species: Human
Sample Types: Cell Culture Supernates

Pang L et al. (2006-01-01), Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J. Immunol., 176(6):3788-95.
PMID: 16517749
Species: Human
Sample Types: Cell Culture Supernates

Beck LA et al. (2006-01-01), Functional analysis of the chemokine receptor CCR3 on airway epithelial cells. J. Immunol., 177(5):3344-54.
PMID: 16920975
Species: Human
Sample Types: Cell Culture Supernates

Smith C et al. (2006-01-01), Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation. J. Am. Coll. Cardiol., 48(8):1591-9.
PMID: 17045893
Species: Human
Sample Types: Sputum

Wilkinson TM et al. (2006-01-01), Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med., 173(8):871-6.
PMID: 16456141
Species: Human
Sample Types: Cell Culture Supernates

Magne D et al. (2006-01-01), The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. Arthritis Res. Ther., 8(3):R80.
PMID: 16646978
Species: Human
Sample Types: Cell Culture Supernates

Hsu YH et al. (2006-01-01), Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis Rheum., 54(9):2722-33.
PMID: 16947773
Species: Human
Sample Types: Tracheal Lavage Fluid

Cotton RB et al. (2006-01-01), Cimetidine does not prevent lung injury in newborn premature infants. Pediatr. Res., 59(6):795-800.
PMID: 16641218
Species: Human
Sample Types: Serum

Sheu JN et al. (2006-01-01), Serum and urine levels of interleukin-6 and interleukin-8 in children with acute pyelonephritis. Cytokine, 36(5):276-82.
PMID: 17374489
Species: Human
Sample Types: Whole Cells

Otterdal K et al. (2006-01-01), Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood, 108(3):928-35.
PMID: 16861346
Species: Human
Sample Types: Urine

Ciszek M et al. (2006-01-01), Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria. Transplantation, 81(12):1653-7.
PMID: 16794530
Species: Human
Sample Types: CSF

Alexander GM et al. (2006-01-01), Changes in immune and glial markers in the CSF of patients with Complex Regional Pain Syndrome. Brain Behav. Immun., 21(5):668-76.
PMID: 17129705
Species: Human
Sample Types: BALF

Antoniou KM et al. (2006-01-01), Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis. Chest, 130(4):982-8.
PMID: 17035428
Species: Human
Sample Types: Plasma

Makis AC et al. (2006-01-01), C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease. Arch. Intern. Med., 166(3):366-8.
PMID: 16476879
Species: Human
Sample Types: Saliva

Wilkinson TM et al. (2006-01-01), Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest, 129(2):317-24.
PMID: 16478847
Species: Human
Sample Types: Nasal Lavage Fluid

Nikasinovic L et al. (2006-01-01), Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children. J. Allergy Clin. Immunol., 117(6):1382-8.
PMID: 16751001
Roos-Engstrand E et al. (2005-01-01), Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure. Eur. Respir. J., 25(5):797-803.
PMID: 15863635
Species: Human
Sample Types: Cell Culture Supernates

Numasaki M et al. (2005-01-01), IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J. Immunol., 175(9):6177-89.
PMID: 16237115
Species: Human
Sample Types: Cell Culture Supernates

Vergne-Salle</LastName><F P</Initial et al. (2005-01-01), Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes. Cytokine, 31(5):335-48.
PMID: 16099671
Species: Primate - Papio hamadryas (Hamadyras Baboon)
Sample Types: Plasma

Bouchama A et al. (2005-01-01), Experimental heatstroke in baboon: analysis of the systemic inflammatory response. Shock, 24(4):332-5.
PMID: 16205317
Species: Human
Sample Types: Sputum

Simpson JL et al. (2005-01-01), Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma. Am. J. Respir. Crit. Care Med., 172(5):559-65.
PMID: 15901607
Species: Human
Sample Types: Cell Culture Supernates

Trevino JG et al. (2005-01-01), Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis. Cancer Res., 65(16):7214-22.
PMID: 16103072
Species: Human
Sample Types: Sputum

Sagel SD et al. (2005-01-01), Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis. Pediatr. Pulmonol., 39(3):224-32.
PMID: 15635615
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Plasma

Bertho JM et al. (2005-01-01), Application of autologous hematopoietic cell therapy to a nonhuman primate model of heterogeneous high-dose irradiation. Radiat. Res., 163(5):557-70.
PMID: 15850418
Species: Human
Sample Types: Cell Culture Supernates

Ren Y et al. (2005-01-01), Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Histopathology, 46(6):659-67.
PMID: 15910597
Species: Human
Sample Types: Cervical Fluid

Jacobsson B et al. (2005-01-01), Interleukin-6 and interleukin-8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes. BJOG, 112(6):719-24.
PMID: 15924526
Species: Human
Sample Types: Cell Culture Supernates

Bartemes KR et al. (2005-01-01), Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions. J. Allergy Clin. Immunol., 116(4):827-35.
PMID: 16210057
Species: Human
Sample Types: Hypersalpingeal Fluid (HSF)

Bedaiwy MA et al. (2005-01-01), Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid. J. Assist. Reprod. Genet., 22(4):161-5.
PMID: 16021860
Species: Human
Sample Types: Nasal Lavage Fluid

Ciprandi G et al. (2005-01-01), Relationships between allergic inflammation and nasal airflow in children with seasonal allergic rhinitis. Ann. Allergy Asthma Immunol., 94(2):258-61.
PMID: 15765742
Species: Human
Sample Types: Sputum

Fujimoto K et al. (2005-01-01), Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease. Eur. Respir. J., 25(4):640-6.
PMID: 15802337
Species: Human
Sample Types: Plasma

Gessler P et al. (2004-01-01), CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery. Shock, 22(6):513-20.
PMID: 15545821
Species: Human
Sample Types: Serum

Khan SS et al. (2004-01-01), Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers. Cytometry B Clin Cytom, 61(1):35-9.
PMID: 15351980
Species: Human
Sample Types: Plasma

Shahbakhti H et al. (2004-01-01), Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo. Photochem. Photobiol., 80(2):231-5.
PMID: 15362934
Species: Rabbit
Sample Types: Synovial Fluid

Tramontini N et al. (2004-01-01), Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum., 50(8):2633-9.
PMID: 15334478
Species: Human
Sample Types: Serum

Chuang CC et al. (2004-01-01), High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor? Crit. Care Med., 32(3):734-9.
PMID: 15090955
Species: Human
Sample Types: Cell Culture Supernates

Mellow TE et al. (2004-01-01), The effect of respiratory synctial virus on chemokine release by differentiated airway epithelium. Exp. Lung Res., 30(1):43-57.
PMID: 14967603
Species: Human
Sample Types: Plasma

Matsushima A et al. (2004-01-01), Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome. J Trauma, 56(2):259-64.
PMID: 14960965
Species: Human
Sample Types: Cell Culture Supernates

Seo KH et al. (2004-01-01), Estrogen enhances angiogenesis through a pathway involving platelet-activating factor-mediated nuclear factor-kappaB activation. Cancer Res., 64(18):6482-8.
PMID: 15374958
Species: Human
Sample Types: Vaginal Lavage Fluid

Fichorova RN (2004-01-01), Guiding the vaginal microbicide trials with biomarkers of inflammation. J. Acquir. Immune Defic. Syndr., 37(0):S184-93.
PMID: 16419271
Species: Human
Sample Types: Serum

Hayakata T et al. (2004-01-01), Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury. Shock, 22(2):102-7.
PMID: 15257081
Species: Human
Sample Types: BALF

Chen LL et al. (2004-01-01), Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects. Chest, 125(6):2328-35.
PMID: 15189958
Species: Human
Sample Types: Sputum

Patel IS et al. (2004-01-01), Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med., 170(4):400-7.
PMID: 15130905
Species: Human
Sample Types: Nasal Lavage Fluid

McShane D et al. (2004-01-01), Normal nasal mucociliary clearance in CF children: evidence against a CFTR-related defect. Eur. Respir. J., 24(1):95-100.
PMID: 15293610
Species: Rabbit
Sample Types: Tissue Homogenates

Kotani M et al. (2004-01-01), Reduced inspiratory flow attenuates IL-8 release and MAPK activation of lung overstretch. Eur. Respir. J., 24(2):238-46.
PMID: 15332391
Species: Human
Sample Types: Peritoneal Fluid

Hellman C et al. (2003-01-01), Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects. Clin. Exp. Immunol., 131(1):75-81.
PMID: 12519389
Species: Human
Sample Types: Pleural Effusion

Park JS et al. (2003-01-01), Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta. Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 57(5):463-9.
PMID: 12753503
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Serum

Geisbert TW et al. (2003-01-01), Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. Am. J. Pathol., 163(6):2347-70.
PMID: 14633608
Species: Human
Sample Types: Serum

Doubrovina ES et al. (2003-01-01), Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J. Immunol., 171(12):6891-9.
PMID: 14662896
Species: Human
Sample Types: Serum

Lamming CE et al. (2003-01-01), Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis. 111(6):811-9.
PMID: 12639987
Species: Human
Sample Types: Serum

Maheshwari A et al. (2003-01-01), ELR+ CXC chemokines in human milk. Cytokine, 24(3):91-102.
PMID: 14581003
Species: Bovine
Sample Types: Milk

Bannerman DD et al. (2003-01-01), Increased levels of LPS-binding protein in bovine blood and milk following bacterial lipopolysaccharide challenge. J. Dairy Sci., 86(10):3128-37.
PMID: 14594231
Species: Human
Sample Types: Gingival Crevicular Fluid (GCF)

Jin LJ et al. (2002-01-01), Relationship of changes in interleukin-8 levels and granulocyte elastase activity in gingival crevicular fluid to subgingival periodontopathogens following non-surgical periodontal therapy in subjects with chronic periodontitis. J. Clin. Periodontol., 29(7):604-14.
PMID: 12354085
Species: Human
Sample Types: Cell Culture Supernates

Huber TB et al. (2002-01-01), Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol., 168(12):6244-52.
PMID: 12055238
Species: Human
Sample Types: Blister Fluid

Baroni A et al. (2002-01-01), Cytokine pattern in blister fluid and sera of patients with pemphigus. Dermatology (Basel), 205(2):116-21.
PMID: 12218224
Species: Human
Sample Types: Urine

Pages F et al. (2002-01-01), Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer. Clin. Exp. Immunol., 127(2):303-9.
PMID: 11876754
Species: Human
Sample Types: Sputum

Wark PA et al. (2002-01-01), Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma. Eur. Respir. J., 20(4):834-40.
PMID: 12412672
Species: Human
Sample Types: Tissue Secretion

Chung MH et al. (2002-01-01), Compositional difference in middle ear effusion: mucous versus serous. Laryngoscope, 112(1):152-5.
PMID: 11802055
Species: Human
Sample Types: Cell Culture Supernates

Messmer D et al. (2002-01-01), Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. J. Immunol., 169(8):4172-82.
PMID: 12370346
Species: Human
Sample Types: Seminal Plasma

Zhang Q et al. (2002-01-01), Detection of fractalkine in human seminal plasma and its role in infertile patients. Hum. Reprod., 17(6):1560-4.
PMID: 12042278
Species: Human
Sample Types: Cell Culture Supernates

D&amp;apos;Ambrosio D (2002-01-01), Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. Eur. J. Immunol., 32(10):2934-43.
PMID: 12355447
Species: Human
Sample Types: Saliva

Wallaert B et al. (2002-01-01), Airway neutrophil inflammation in nonasthmatic patients with food allergy. Allergy, 57(5):405-10.
PMID: 11972479
Species: Human
Sample Types: Peritoneal Fluid

Gomez-Torres MJ et al. (2002-01-01), Embryotoxicity of peritoneal fluid in women with endometriosis. Its relation with cytokines and lymphocyte populations. Hum. Reprod., 17(3):777-81.
PMID: 11870135
Species: Human
Sample Types: Saliva

Gompertz S et al. (2001-01-01), Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD. `„ÞRqp&±šú°†0~«Â‹9ê¢ü JÕÈ$GôÏf–4± beta ~lþ8Wúu“ƒ•îçÐ00©Ù°x°Ï*á|øB´Æ‘?+@“ÞQ}¨»9‡m£Íå8¬vT?[A¥±¶Üùæ¨ÜnU™-™œŠ!Þ‰êÖYí—ÁjyŸÁ}®)¢2A, 2001;56(1):36-41.
PMID: 11120902
Species: Human
Sample Types: Cell Culture Supernates

Yates SL et al. (2000-01-01), Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J. Neurochem., 74(3):1017-25.
PMID: 10693932
Species: Human
Sample Types: Gut Lavage Fluid

Evgenikos NL et al. (2000-01-01), Luminal neutrophil migration in ileoanal pouches studied by whole gut lavage. Eur J Gastroenterol Hepatol, 12(5):553-7.
PMID: 10833100
Species: Primate - Papio cynocephalus (Yellow Baboon)
Sample Types: Serum

Welty-Wolf KE et al. (2000-01-01), Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy. 1-23, 13(5):404-9.
PMID: 10807017
Species: Human
Sample Types: Cell Culture Supernates

Westphal JR et al. (2000-01-01), Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts in vivo. Int. J. Cancer, 86(6):768-76.
PMID: 10842189
Species: Human
Sample Types: Cell Culture Supernates

Attur MG et al. (2000-01-01), Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins. J. Immunol., 164(5):2684-91.
PMID: 10679109
Species: Bovine
Sample Types: Serum

Shuster DE et al. (1997-01-01), Complement fragment C5a and inflammatory cytokines in neutrophil recruitment during intramammary infection with Escherichia coli. Infect. Immun., 65(8):3286-92.
PMID: 9234788
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Cell Culture Supernates

Lehner T et al. (1996-01-01), Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. , 2(7):767-75.
PMID: 8673922
Species: Human
Sample Types: Cell Culture Supernates

Rudisch A et al. (), High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS ON10(4):e0124283.
PMID: 25919140

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Customer Reviews for Human IL-8/CXCL8 Quantikine ELISA Kit (11)

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Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Khuynh Nguyen

Sample Tested: Caco-2 human colorectal adenocarcinoma cell line

Verified Customer | Posted 05/06/2023

This product works very well
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/24/2023
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Plasma,Urine

Verified Customer | Posted 11/07/2022

Can detect in normal urine at low levels. Urine was measured neat, 4-fold, and 16-fold. Could not detect in plasma run neat.
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: human aortic endothelial cells

Verified Customer | Posted 12/06/2019
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Nicole Stone

Sample Tested: Human cell conditioned medium

Verified Customer | Posted 01/17/2019

Great product! Very easy to use
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Cell Culture Media

Verified Customer | Posted 05/02/2018
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Alisha Freeman

Sample Tested: CHO Chinese hamster ovary cell line

Verified Customer | Posted 04/24/2018
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Leslie Priddy

Sample Tested: Serum

Verified Customer | Posted 04/01/2018
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Balaji Mahender

Sample Tested: EDTA Plasma

Verified Customer | Posted 01/18/2018
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Jim Hsiao

Sample Tested: Primary human lung fibroblasts

Verified Customer | Posted 12/04/2017

This result has been published in PlosONE journal: 10.1371/journal.pone.0058258
Human IL-8/CXCL8 Quantikine ELISA Kit

Name: Michelle Chen

Sample Tested: A375 human melanoma cell line

Verified Customer | Posted 04/26/2017

Supernatents of A375-MA2 treated with siCtrl or siIL-8 were assessed using IL-8 ELISA (R&D).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Human IL-8/CXCL8 Quantikine ELISA Kit

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Customer Reviews for Human IL-8/CXCL8 Quantikine ELISA Kit (11)

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Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

Human IL-8/CXCL8 Quantikine ELISA Kit

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