Recombinant Human IFN-gamma Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | E. coli |
Accession #: | CAA31639 |
Applications: | Bioactivity |
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Citations for Recombinant Human IFN-gamma Protein (417)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human IFN-gamma Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayPL Chi et al. (2022-01-01), MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension International journal of biological sciences, 18(1):331-348.
PMID: 34975336 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureP Sekhri et al. (2022-01-01), The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells Cancers, 14(6).
PMID: 35326601 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Schmit et al. (2022-01-01), Interferon-gamma promotes monocyte-mediated lung injury during influenza infection Cell Reports, 38(9):110456.
PMID: 35235782 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Hong et al. (2022-01-01), Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells International Journal of Molecular Sciences, 23(8).
PMID: 35457288 -
Species: Human
Sample Types: Whole Cell
Applications: Bio-assayDY Zander et al. (2022-01-01), Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death Cell Death Disease, 2022;13(4):364.
PMID: 35436994 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Fedoriw et al. (2022-01-01), Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response Cancer Immunology Research, 0(0).
PMID: 35181787 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Mitra et al. (2022-01-01), Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy International Journal of Molecular Sciences, 23(16).
PMID: 36012296 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Casciola-R et al. (2022-01-01), IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function JCI Insight, 7(9).
PMID: 35349483 -
Species: Human
Sample Types: Whole Cell
Applications: Cell CultureT Meyer et al. (2022-01-01), NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity Proceedings of the National Academy of Sciences of the United States of America, 119(35):e2211310119.
PMID: 35994674 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Chandrasek et al. (2022-01-01), IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii Nature Communications, 13(1):4605.
PMID: 35941154 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCW Lee et al. (2022-01-01), Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells Journal of advanced research, 39(0):73-88.
PMID: 35777918 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Yoshinaga et al. (2022-01-01), Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets Stem Cell Reports, 0(0).
PMID: 35750044 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Iverson et al. (2022-01-01), Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium MBio, 0(0):e0105522.
PMID: 35699372 -
Species: Human
Sample Types: Organoid
Applications: BioassayP Pavlidis et al. (2022-01-01), Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease Cell Reports, 40(13):111439.
PMID: 36170836 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXJ Mi et al. (2022-01-01), In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals Journal of ethnopharmacology, 296(0):115523.
PMID: 35809756 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZ Zhang et al. (2022-01-01), Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity Nature Communications, 13(1):4136.
PMID: 35842425 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Padmanabha et al. (2022-01-01), IFNgamma-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling Cellular Signalling, 97(0):110400.
PMID: 35820543 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayMD Gundersen et al. (2022-01-01), Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis Scientific Reports, 12(1):11550.
PMID: 35798804 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureH Asashima et al. (2022-01-01), PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection Cell Reports, 0(0):111895.
PMID: 36596303 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Hayashi et al. (2022-01-01), Intestinal epithelial BLT1 promotes mucosal repair JCI Insight, 0(0).
PMID: 36301666 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Turner et al. (2022-01-01), CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy Cancers, 14(21).
PMID: 36358868 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureAC Tecalco-Cr et al. (2021-01-01), Identification of genes modulated by interferon gamma in breast cancer cells Biochemistry and Biophysics Reports, 27(0):101053.
PMID: 34189281 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMC Suárez-Arr et al. (2021-01-01), Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity Cancers, 13(9).
PMID: 34067089 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBY Wang et al. (2021-01-01), Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease Neural regeneration research, 16(12):2521-2527.
PMID: 33907043 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySP Totten et al. (2021-01-01), STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer Nature Communications, 12(1):3299.
PMID: 34083537 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYH Liang et al. (2021-01-01), Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing Scientific Reports, 11(1):9080.
PMID: 33907276 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Luna-Yolba et al. (2021-01-01), Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells Cancers, 13(14).
PMID: 34298712 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Luostarine et al. (2021-01-01), The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells Pulmonary pharmacology therapeutics, 2021;70(0):102059.
PMID: 34302984 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Lobato-Már et al. (2021-01-01), Mechanistic insight into bacterial entrapment by septin cage reconstitution Nature Communications, 12(1):4511.
PMID: 34301939 -
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA (Capture)JS Aguilar Dí et al. (2021-01-01), Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells Journal of Cancer, 12(16):4993-5004.
PMID: 34234868 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Yang et al. (2021-01-01), FKBP3 Induces Human Immunodeficiency Virus Type 1 Latency by Recruiting Histone Deacetylase 1/2 to the Viral Long Terminal Repeat MBio, 0(0):e0079521.
PMID: 34281390 -
Species: Human
Sample Types: Organoid
Applications: BioassayC Prelli Boz et al. (2021-01-01), IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro Nature Communications, 12(1):4584.
PMID: 34321474 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Nakajima et al. (2021-01-01), The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells Scientific Reports, 11(1):16891.
PMID: 34413454 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Azari et al. (2021-01-01), Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors MBio, 12(4):e0184921.
PMID: 34399615 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXY Zhu et al. (2021-01-01), Impaired immunomodulatory capacity in adipose tissue-derived mesenchymal stem/stromal cells isolated from obese patients Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34418300 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Abu-Shahba et al. (2021-01-01), Impact of Type 2 Diabetes Mellitus on the Immunoregulatory Characteristics of Adipose Tissue-Derived Mesenchymal Stem Cells The international journal of biochemistry cell biology, 2021;0(0):106072.
PMID: 34455058 -
Species: Human
Sample Types: Whole Cell
Applications: StimulationS Wüst et al. (2021-01-01), Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses Cells, 10(10).
PMID: 34685580 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Wang et al. (2021-01-01), SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms Scientific Reports, 11(1):1399.
PMID: 33446805 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Gunawardan et al. (2021-01-01), Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 11(1):1949.
PMID: 33479269 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Shao et al. (2021-01-01), Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris JCI Insight, 0(0).
PMID: 34491907 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTM Garcia-Bat et al. (2021-01-01), Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes EBioMedicine, 63(0):103175.
PMID: 33450518 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Jerby-Arno et al. (2021-01-01), Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma Nature Medicine, 0(0).
PMID: 33495604 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayHJ Lee et al. (2021-01-01), IFN-gamma Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application BioMed Research International, 2021(0):4604856.
PMID: 34527737 -
Species: Human
Sample Types: Organoid
Applications: BioassayY Cheng et al. (2021-01-01), Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease EBioMedicine, 75(0):103758.
PMID: 34933179 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySR Rosenbaum et al. (2021-01-01), SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects Cell Reports, 37(10):110085.
PMID: 34879275 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Song et al. (2021-01-01), Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation Nucleic Acids Research, 0(0).
PMID: 34791430 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayA Fu et al. (2021-01-01), Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets Cell Reports, 37(8):110037.
PMID: 34818536 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Kim et al. (2021-01-01), TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment Cell Reports, 37(7):110018.
PMID: 34788612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYH Liang et al. (2021-01-01), Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells Journal of Biomedical Science, 28(1):75.
PMID: 34758826 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Pettmann et al. (2021-01-01), The discriminatory power of the T cell receptor Elife, 10(0).
PMID: 34030769 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureJ Kim et al. (2021-01-01), A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells Cells, 11(1).
PMID: 35011581 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Xu et al. (2021-01-01), Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling The Journal of Biological Chemistry, 0(0):101380.
PMID: 34740611 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Lee et al. (2021-01-01), Skullcapflavone II Suppresses TNF-alpha/IFN-gamma-Induced TARC, MDC, and CTSS Production in HaCaT Cells International Journal of Molecular Sciences, 22(12).
PMID: 34208434 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Seime et al. (2021-01-01), Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification Cells, 10(6).
PMID: 34063989 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayML Amin et al. (2020-01-01), Immunomodulatory properties of photopolymerizable fucoidan and carrageenans Carbohydr Polym, 230(0):115691.
PMID: 31887956 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureK Yoshida et al. (2020-01-01), Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells BMC Cancer, 20(1):25.
PMID: 31914969 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYD Kim et al. (2020-01-01), HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment J Cancer, 11(14):4059-4072.
PMID: 32368288 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Shan et al. (2020-01-01), Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization J. Cell. Mol. Med., 0(0).
PMID: 32469149 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Liu et al. (2020-01-01), Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy JCI Insight, 0(0).
PMID: 32427583 -
Species: Human
Applications: Cell CultureH Ray-Jones et al. (2020-01-01), Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31 BMC Biol., 18(1):47.
PMID: 32366252 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureMN Dehno et al. (2020-01-01), Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer Int J Mol Sci, 21(9).
PMID: 32349280 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Zhu et al. (2020-01-01), Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb Stem Cell Res Ther, 11(1):162.
PMID: 32321589 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureAM Kell et al. (2020-01-01), RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit�Hantaan orthohantavirus replication PLoS Pathog., 16(4):e1008483.
PMID: 32330200 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureA Nikonova et al. (2020-01-01), M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations EBioMedicine, 54(0):102734.
PMID: 32279057 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMY Hsieh et al. (2020-01-01), Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES) Biomed J, 0(0).
PMID: 32651134 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureH El-Kehdy et al. (2020-01-01), Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells Cells, 9(7).
PMID: 32650454 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNC Leite et al. (2020-01-01), Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells Cell Rep, 32(2):107894.
PMID: 32668238 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureC Su et al. (2020-01-01), Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells Nat Commun, 11(1):3294.
PMID: 32620744 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureK Das Gupta et al. (2020-01-01), Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2 Cell Rep, 30(8):2712-2728.e8.
PMID: 32101747 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJF Marchini et al. (2020-01-01), Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles J Am Heart Assoc, 9(15):e015878.
PMID: 32750308 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureR Abreu et al. (2020-01-01), Interferon-gamma promotes iron export in human macrophages to limit intracellular bacterial replication PLoS ONE, 15(12):e0240949.
PMID: 33290416 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureJ Bhushan et al. (2020-01-01), ISG15 Connects Autophagy and IFN-&gamma-Dependent Control of Toxoplasma gondii Infection in Human Cells MBio, 11(5).
PMID: 33024031 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureT Nicotra et al. (2020-01-01), Mesenchymal stem/stromal cell quality control: validation of mixed lymphocyte reaction assay using flow cytometry according to ICH Q2(R1) Stem Cell Res Ther, 11(1):426.
PMID: 33004063 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Abu-Shah et al. (2020-01-01), Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses J. Immunol., 0(0).
PMID: 32817332 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Panagiotak et al. (2020-01-01), Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells Nat Commun, 11(1):5163.
PMID: 33057020 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureX Li et al. (2020-01-01), 18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model Onco Targets Ther, 13(0):11659-11668.
PMID: 33223839 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayB Cioni et al. (2020-01-01), Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion Nat Commun, 11(1):4498.
PMID: 32908142 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureB ?y?y?ska-G et al. (2020-01-01), The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor Sci Rep, 10(1):2886.
PMID: 32076052 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Yan et al. (2020-01-01), T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 31(13):107820.
PMID: 32610123 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Wu et al. (2020-01-01), Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis Cell Res., 0(0).
PMID: 32546764 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Kim et al. (2020-01-01), Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia Cells, 9(9).
PMID: 32878300 -
Species: Human
Sample Types: Whole Cells
ZZ Bai et al. (2020-01-01), M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-&kappaB Signaling Pathway Nanoscale research letters, 15(1):221.
PMID: 33263825 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureEM Wilfong et al. (2020-01-01), Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation PLoS ONE, 15(10):e0240319.
PMID: 33021986 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Yakimovich et al. (2020-01-01), Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection mSphere, 5(5).
PMID: 32907956 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureC Li et al. (2020-01-01), Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity Oncogene, 0(0).
PMID: 33323966 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Fisch et al. (2020-01-01), Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death Cell Rep, 32(6):108008.
PMID: 32783936 -
Species: Human
Sample Types: Protein
Applications: BioassaySA Tarasov et al. (2020-01-01), Insights into the Mechanism of Action of Highly Diluted Biologics J. Immunol., 0(0).
PMID: 32727888 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Gustafsson et al. (2020-01-01), Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model J. Dermatol. Sci., 0(0).
PMID: 32782183 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell CultureF Duan et al. (2020-01-01), Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2 Res Sq, 0(0).
PMID: 32839764 -
Species: Human
Sample Types: Protein
Applications: BioassayMC Cavé et al. (2020-01-01), Glycosaminoglycans bind human IL-27 and regulate its activity Eur. J. Immunol., 0(0).
PMID: 32483835 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAL Samson et al. (2020-01-01), MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis Nat Commun, 11(1):3151.
PMID: 32561730 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Gettler et al. (2019-01-01), Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets Genes Immun., 0(0).
PMID: 30692607 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Cruz-Ramos et al. (2019-01-01), Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells Int. J. Biochem. Cell Biol., 107(0):14-26.
PMID: 30529400 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Spekker-Bo et al. (2019-01-01), hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye Int J Mol Sci, 20(4).
PMID: 30781494 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySE Jin et al. (2019-01-01), Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes Molecules, 24(2).
PMID: 30642008 -
Species: Human
Applications: BioassayF Feng et al. (2019-01-01), Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells Viruses, 11(2).
PMID: 30781810 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBA Kane et al. (2019-01-01), Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis Sci Rep, 9(1):1149.
PMID: 30718719 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Kita et al. (2019-01-01), Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells Sci Rep, 9(1):3135.
PMID: 30816271 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Karnezis et al. (2019-01-01), CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS Cancer Res., 0(0).
PMID: 30709930 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJC de Quaglia et al. (2019-01-01), Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis J Immunol Res, 2019(0):1529189.
PMID: 30882002 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Ashizawa et al. (2019-01-01), microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L1 Mol. Cancer Res., 0(0).
PMID: 30872332 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Roper et al. (2019-01-01), APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors Cell Rep, 26(10):2651-2666.e6.
PMID: 30840888 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAT Dang et al. (2019-01-01), Autophagy links antimicrobial activity with antigen presentation in Langerhans cells JCI Insight, 4(8).
PMID: 30996142 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Vander Bek et al. (2019-01-01), Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 0(0).
PMID: 31002437 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Ruiz et al. (2019-01-01), DNA from virulent M. tuberculosis induces TNF-? production and autophagy in M1 polarized macrophages Microb. Pathog., 0(0).
PMID: 31054870 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCH Yu et al. (2019-01-01), Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation Int J Mol Sci, 20(11).
PMID: 31141897 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySM Ferrari et al. (2019-01-01), Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy Autoimmun Rev, 0(0).
PMID: 31059842 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Wu et al. (2019-01-01), IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells J. Immunol., 0(0).
PMID: 31548328 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Ménard et al. (2019-01-01), Integrated Transcriptomic, Phenotypic, and Functional Study Reveals Tissue-Specific Immune Properties of Mesenchymal Stromal Cells Stem Cells, 0(0).
PMID: 31502731 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Merriman et al. (2019-01-01), Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress J. Biol. Chem., 0(0).
PMID: 31591269 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureLNS Andrade et al. (2019-01-01), Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy Sci Rep, 9(1):14482.
PMID: 31597943 -
Species: Human
Sample Types: Serum
Applications: ELISA StandardA Stumpf et al. (2019-01-01), Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum PLoS ONE, 14(12):e0225525.
PMID: 31790441 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Deli? et al. (2019-01-01), Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients J. Dermatol. Sci., 0(0).
PMID: 31843230 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLA Callender et al. (2019-01-01), Mitochondrial mass governs the extent of human T cell senescence Aging Cell, 0(0):e13067.
PMID: 31788930 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureN Berges et al. (2019-01-01), Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform PLoS ONE, 14(11):e0225081.
PMID: 31703097 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureE Biros et al. (2019-01-01), Mini tryptophanyl-tRNA synthetase is required for a synthetic phenotype in vascular smooth muscle cells induced by IFN-?-mediated beta2-adrenoceptor signaling Cytokine, 127(0):154940.
PMID: 31786502 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureSM Huang et al. (2019-01-01), High glucose environment induces M1 macrophage polarization that impairs keratinocyte migration via TNF-alpha: An important mechanism to delay the diabetic wound healing J. Dermatol. Sci., 0(0).
PMID: 31761388 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureWB Hamilton et al. (2019-01-01), Dynamic lineage priming is driven via direct enhancer regulation by ERK Nature, 575(7782):355-360.
PMID: 31695196 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureKA Jha et al. (2019-01-01), TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation Stem Cell Res Ther, 10(1):318.
PMID: 31690344 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureW Nowak et al. (2019-01-01), Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR EBioMedicine, 0(0).
PMID: 31753725 -
Species: Human
Sample Types: Organoid
Applications: BioassayM Pascual-Ga et al. (2019-01-01), LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy Nat Commun, 10(1):2416.
PMID: 31186412 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKJ Pahk et al. (2019-01-01), Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers Sci Rep, 9(1):9050.
PMID: 31227775 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Zhang et al. (2018-01-01), Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells J Cancer, 9(2):367-374.
PMID: 29344283 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Nakagawa et al. (2018-01-01), Intratumoral delivery of an adenoviral vector carrying the SOCS-1 gene enhances T cell-mediated anti-tumor immunity by suppressing PD-L1 Mol. Cancer Ther., 0(0).
PMID: 29891489 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEY Huang et al. (2018-01-01), Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages BMC Cancer, 18(1):321.
PMID: 29580202 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Vermi et al. (2018-01-01), slan+ monocytes and macrophages mediate CD20-dependent B cell lymphoma elimination via ADCC and ADCP Cancer Res., 0(0).
PMID: 29748373 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLCD Smyth et al. (2018-01-01), Unique and shared inflammatory profiles of human brain endothelia and pericytes J Neuroinflammation, 15(1):138.
PMID: 29751771 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Sireesh et al. (2018-01-01), Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus Sci Rep, 8(1):5126.
PMID: 29572460 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayG Genard et al. (2018-01-01), Proton irradiation orchestrates macrophage reprogramming through NF?B signaling Cell Death Dis, 9(7):728.
PMID: 29950610 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Nagel et al. (2018-01-01), Aberrant expression of NKL homeobox gene HLX in Hodgkin lymphoma Oncotarget, 9(18):14338-14353.
PMID: 29581848 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKC Osum et al. (2018-01-01), Interferon-gamma drives programmed death-ligand 1 expression on islet ? cells to limit T cell function during autoimmune diabetes Sci Rep, 8(1):8295.
PMID: 29844327 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS McGarrity et al. (2018-01-01), Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification Sci Rep, 8(1):6811.
PMID: 29717213 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Palazzo et al. (2018-01-01), The PI3K?-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo J. Immunol., 0(0).
PMID: 29453281 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJA Marwick et al. (2018-01-01), Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation Cell Death Dis, 9(6):665.
PMID: 29867198 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Sugita et al. (2018-01-01), Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., 59(5):1719-1731.
PMID: 29610856 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Vorkapic et al. (2018-01-01), Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms Mol Med Rep, 0(0).
PMID: 29749489 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Oth et al. (2018-01-01), Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-? BMC Immunol., 19(1):8.
PMID: 29433450 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAE Dodi et al. (2018-01-01), Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli Respir. Res., 19(1):91.
PMID: 29747634 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Lema et al. (2018-01-01), High-Mobility Group Box 1 in Dry Eye Inflammation Invest. Ophthalmol. Vis. Sci., 59(5):1741-1750.
PMID: 29610858 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRB Nahomi et al. (2018-01-01), The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice Invest. Ophthalmol. Vis. Sci., 59(5):2042-2053.
PMID: 29677366 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Huang et al. (2018-01-01), MicroRNA-374b inhibits liver cancer progression via down regulating programmed cell death-1 expression on cytokine-induced killer cells Oncol Lett, 15(4):4797-4804.
PMID: 29552119 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Oshima et al. (2018-01-01), Virus-like infection induces human ? cell dedifferentiation JCI Insight, 3(3).
PMID: 29415896 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Singh et al. (2018-01-01), Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis Autophagy, 0(0):1-57.
PMID: 29457983 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Schwede et al. (2018-01-01), Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-? Physiol Rep, 6(16):e13831.
PMID: 30136410 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Terkawi et al. (2018-01-01), Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes J Immunol Res, 2018(0):6709424.
PMID: 30069491 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySL Figenschau et al. (2018-01-01), ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes Sci Rep, 8(1):11720.
PMID: 30082828 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zou et al. (2018-01-01), The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells J. Biol. Chem., 0(0).
PMID: 30135206 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNM Plugis et al. (2018-01-01), Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30104382 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCH Lu et al. (2018-01-01), USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation Oncogene, 0(0).
PMID: 30038267 -
Species: Human
Sample Types: Transfected Whole Cells
Applications: BioassayI Cañadas et al. (2018-01-01), Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses Nat. Med., 0(0).
PMID: 30038220 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayED Anderson et al. (2018-01-01), Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632 PLoS ONE, 13(9):e0198862.
PMID: 30208113 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Yang et al. (2018-01-01), Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system BMC Cancer, 18(1):984.
PMID: 30326865 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTJ Bussian et al. (2018-01-01), Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline Nature, 0(0).
PMID: 30232451 -
Species: Human
Sample Types: Plasma
J Hrdý et al. (2018-01-01), Decreased allergy incidence in children supplemented with E. coli O83:K24:H31 and its possible modes of action Eur. J. Immunol., 0(0).
PMID: 30306557 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAC Tecalco-Cr et al. (2018-01-01), Interplay between interferon-stimulated gene 15/ISGylation and interferon gamma signaling in breast cancer cells Cell. Signal., 54(0):91-101.
PMID: 30500379 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayML Ibrahim et al. (2018-01-01), Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis Cell Rep, 25(11):3036-3046.e6.
PMID: 30540937 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Vaeteewoot et al. (2018-01-01), Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis Transl Oncol, 12(2):217-225.
PMID: 30415063 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDA Bejarano et al. (2018-01-01), Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages Viruses, 10(11).
PMID: 30423802 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Muntaka et al. (2018-01-01), IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection Infect. Immun., 0(0).
PMID: 30455194 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHK Park et al. (2018-01-01), Status of programmed death-ligand 1 expression in sarcomas J Transl Med, 16(1):303.
PMID: 30400799 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Tomi? et al. (2018-01-01), Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells Int J Nanomedicine, 13(0):6941-6960.
PMID: 30464452 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Mulati et al. (2018-01-01), VISTA expressed in tumour cells regulates T cell function Br. J. Cancer, 0(0).
PMID: 30382166 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Rentschler et al. (2018-01-01), Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence Cell. Physiol. Biochem., 51(3):1103-1118.
PMID: 30476917 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Mercurio et al. (2018-01-01), IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment Cell Death Dis, 9(11):1104.
PMID: 30377293 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2018-01-01), Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer Cancer Immunol Res, 0(0).
PMID: 30396909 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWY Lei et al. (2018-01-01), Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines J Immunol Res, 2018(0):8363265.
PMID: 30648121 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Bai et al. (2018-01-01), Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells Stem Cells Int, 2018(0):6082956.
PMID: 30622567 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Sun et al. (2018-01-01), INF-?: A new spotlight in innate immunity against influenza virus infection Protein Cell, 0(0).
PMID: 29332267 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTA Nakada et al. (2018-01-01), The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock J Innate Immun, 0(0).
PMID: 29334679 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDJ Sharkey et al. (2018-01-01), Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 0(0).
PMID: 29596569 -
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, DifferentiationMW Tang et al. (2018-01-01), Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes Rheumatology (Oxford), 0(0).
PMID: 29471421 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureAJ Lakhter et al. (2018-01-01), Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes Diabetologia, 0(0).
PMID: 29445851 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Huang et al. (2018-01-01), The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A�expression Clin. Cancer Res., 0(0).
PMID: 29496759 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTD Jung et al. (2018-01-01), Changes in the Anti-Allergic Activities of Sesame by Bioconversion Nutrients, 10(2).
PMID: 29443928 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureWR Swindell et al. (2018-01-01), RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature Front Immunol, 9(0):80.
PMID: 29434599 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureC Breuker et al. (2018-01-01), Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women Metab. Clin. Exp., 0(0).
PMID: 29410345 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Ilic et al. (2018-01-01), Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4 Front Immunol, 9(0):11.
PMID: 29416536 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCW Li et al. (2018-01-01), Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1 Cancer Cell, 33(2):187-201.e10.
PMID: 29438695 -
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, DifferentiationI Pop?na et al. (2018-01-01), Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages Cell Commun. Signal, 16(1):17.
PMID: 29690889 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Zhang et al. (2017-01-01), Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan J Hematol Oncol, 10(1):56.
PMID: 28228105 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Hakimzadeh et al. (2017-01-01), Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients Sci Rep, 7(1):1532.
PMID: 28484274 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Nagy et al. (2017-01-01), Interferon-? Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves Am. J. Pathol., 0(0).
PMID: 28431214 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Schumacher et al. (2017-01-01), ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation Cell Death Dis, 8(2):e2622.
PMID: 28230865 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBF Wang et al. (2017-01-01), Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps Allergy, 0(0).
PMID: 28258963 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMW Tang et al. (2017-01-01), Rheumatoid arthritis and psoriatic arthritis synovial fluid stimulates prolactin production by macrophages J. Leukoc. Biol., 0(0).
PMID: 28642278 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE El Darzi et al. (2017-01-01), Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide Int J Immunopathol Pharmacol, 0(0):3946320177076.
PMID: 28449603 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Arruda-Sil et al. (2017-01-01), Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNF? Front Cell Infect Microbiol, 7(0):176.
PMID: 28553619 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMJ Bae et al. (2017-01-01), Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages Tuberc Respir Dis (Seoul), 80(1):77-82.
PMID: 28119750 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Liu et al. (2017-01-01), Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor J. Immunol., 0(0).
PMID: 28947539 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Labrousse- et al. (2017-01-01), VHL promotes immune response against renal cell carcinoma via NF-?B-dependent regulation of VCAM-1 J. Cell Biol, 0(0).
PMID: 28235946 -
Species: Human
Sample Types: Organoids
Applications: BioassayRW Jenkins et al. (2017-01-01), Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids Cancer Discov, 0(0).
PMID: 29101162 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Tian et al. (2017-01-01), Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming Nature, 0(0).
PMID: 28371798 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJY Ao et al. (2017-01-01), Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma Mol. Cancer Ther., 0(0).
PMID: 28572167 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Starc et al. (2017-01-01), Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency Sci Rep, 7(1):8153.
PMID: 28811575 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Wang et al. (2017-01-01), Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions J Extracell Vesicles, 6(1):1314073.
PMID: 28473886 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Qin et al. (2017-01-01), SPI-2/CrmA inhibits IFN-? induction by targeting TBK1/IKK? Sci Rep, 7(1):10495.
PMID: 28874755 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Huang et al. (2017-01-01), Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC Oncotarget, 8(8):13116-13125.
PMID: 28061450 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAC Tecalco Cr et al. (2017-01-01), Cell type-dependent regulation of free ISG15 levels and ISGylation J Cell Commun Signal, 0(0).
PMID: 28285335 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2017-01-01), Curcumin induces apoptosis in human leukemic cell lines through an IFIT2-dependent pathway Cancer Biol. Ther, 0(0):1-8.
PMID: 28071969 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, cE Redondo-Ca et al. (2017-01-01), Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro Stem Cell Res Ther, 8(1):79.
PMID: 28412968 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJS Ainscough et al. (2017-01-01), Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36? Proc. Natl. Acad. Sci. U.S.A, 114(13):E2748-E2757.
PMID: 28289191 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHC Hsia et al. (2017-01-01), Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity J. Biol. Chem, 0(0).
PMID: 28188292 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAC Lundell et al. (2017-01-01), IFN type I and II induce BAFF secretion from human decidual stromal cells Sci Rep, 7(0):39904.
PMID: 28057926 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNN Mehta et al. (2017-01-01), IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis Sci Rep, 7(1):13831.
PMID: 29062018 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMH van Atteku et al. (2017-01-01), Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia Oncogene, 0(0).
PMID: 28192408 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHM Rostam et al. (2017-01-01), Image based Machine Learning for identification of macrophage subsets Sci Rep, 7(1):3521.
PMID: 28615717 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayA Raimondo et al. (2017-01-01), Psoriatic cutaneous inflammation promotes human monocyte differentiation into active osteoclasts, facilitating bone damage Eur. J. Immunol., 0(0).
PMID: 28386999 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Arai et al. (2017-01-01), Salt suppresses IFN? inducible chemokines through the IFN?-JAK1-STAT1 signaling pathway in proximal tubular cells Sci Rep, 7(0):46580.
PMID: 28425456 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Basu et al. (2017-01-01), Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon Nucleic Acids Res., 0(0).
PMID: 29069516 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Qin et al. (2017-01-01), Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii Proc. Natl. Acad. Sci. U.S.A, 0(0).
PMID: 28123064 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQ Wu et al. (2017-01-01), NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy Cell Death Differ., 0(0).
PMID: 28574504 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJD Widdringto et al. (2017-01-01), Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-? J. Allergy Clin. Immunol., 0(0).
PMID: 28629747 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Terkawi et al. (2017-01-01), Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum Sci Rep, 7(0):41772.
PMID: 28181499 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Pavesi et al. (2017-01-01), A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors JCI Insight, 2(12).
PMID: 28614795 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Bruen et al. (2017-01-01), Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 16(1):143.
PMID: 29110715 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells Int J Mol Sci, 17(11).
PMID: 27845745 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells PLoS ONE, 11(12):e0167361.
PMID: 27907087 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Interferon-? blocks signalling through PDGFR? in human brain pericytes J Neuroinflammation, 13(1):249.
PMID: 27654972 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic Proc Natl Acad Sci USA, 113(38):10643-10648.
PMID: 27601677 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRobert Sabat (2016-01-01), MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations Mediators Inflamm., 2016(0):4097574.
PMID: 27843200 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayG Karina Chimal-Ram (2016-01-01), Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes J Immunol Res, 2016(0):6031486.
PMID: 27376091 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Liu et al. (2016-01-01), Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis Stem Cell Res Ther, 7(1):63.
PMID: 27107963 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: BioassayMartine Schrøder (2016-01-01), CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits PLoS ONE, 11(6):e0157387.
PMID: 27311059 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGuo Z et al. (2016-01-01), Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex. PLoS ONE, 11(1):e0146640.
PMID: 26751080 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQiyun Zhu (2016-01-01), Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-? Signaling Pathways by Targeting VISA J. Immunol., 0(0).
PMID: 27821666 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKellie N Smith (2016-01-01), Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells MBio, 7(3).
PMID: 27247230 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySusheela Tridandapa (2016-01-01), Interferon-? Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells J. Biol. Chem., 291(49):25656-25666.
PMID: 27780867 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells Elife, 5(0).
PMID: 27644592 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySW Jackson et al. (2016-01-01), B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6 J Exp Med, 0(0).
PMID: 27069113 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), PD-1/PD-L1 blockade enhances T cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors Clin Cancer Res, 0(0).
PMID: 27470968 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA Mol Immunol, 77(0):205-212.
PMID: 27541693 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway Mucosal Immunol, 0(0).
PMID: 27649928 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients BMC Cancer, 16(1):744.
PMID: 27658492 -
Species: Human
Sample Types: Plasma
Applications: Western Blot(2016-01-01), Identification of a major epitope by anti-interferon-? autoantibodies in patients with mycobacterial disease Nat Med, 0(0).
PMID: 27525523 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMark L Chiu (2016-01-01), Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody J. Biol. Chem., 0(0).
PMID: 27856634 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAndrea Todisco (2016-01-01), Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation Am. J. Physiol. Gastrointest. Liver Physiol., 0(0):ajpgi.00169.2.
PMID: 27856416 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNicholas M Plugis (2016-01-01), Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: Implications for Celiac Disease J. Biol. Chem, 0(0).
PMID: 28003361 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNagarsheth N et al. (2016-01-01), PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. Cancer Res, 76(2):275-82.
PMID: 26567139 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTakuya Matsumoto (2016-01-01), Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages Arthritis Res Ther, 18(1):133.
PMID: 27267914 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-01-01), Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 6(0):29712.
PMID: 27431276 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhao Y et al. (2015-01-01), Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate. Eur J Immunol, 45(9):2494-503.
PMID: 25959978 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHerova M et al. (2015-01-01), ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 194(5):2330-7.
PMID: 25637017 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHowland S et al. (2015-01-01), Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog, 11(6):e1004963.
PMID: 26046849 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySugita S et al. (2015-01-01), Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 56(2):1051-62.
PMID: 25604685 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAbiko K et al. (2015-01-01), IFN-gamma from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer. Br J Cancer, 112(9):1501-9.
PMID: 25867264 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySingh S et al. (2015-01-01), Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-gamma-treated macrophages to Pseudomonas aeruginosa infection. PLoS ONE, 10(2):e0117447.
PMID: 25706389 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRhein B et al. (2015-01-01), Interferon-gamma Inhibits Ebola Virus Infection. PLoS Pathog, 11(11):e1005263.
PMID: 26562011 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySpampinato S et al. (2015-01-01), Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? PLoS ONE, 10(7):e0133392.
PMID: 26197437 -
Sundnes O et al. (2015-01-01), Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences. J Invest Dermatol, 135(7):1771-80.
PMID: 25739051 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChiu E et al. (2015-01-01), Identification of a nuclear export sequence in the MHC CIITA. J Immunol, 194(12):6102-11.
PMID: 25948812 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKwofie K et al. (2015-01-01), Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M. Respir Res, 16(0):14.
PMID: 25849622 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFolgiero V et al. (2015-01-01), TIM-3/Gal-9 interaction induces IFNgamma-dependent IDO1 expression in acute myeloid leukemia blast cells. J Hematol Oncol, 8(0):36.
PMID: 25886742 -
Catanzaro D et al. (2015-01-01), Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage. PLoS ONE, 10(5):e0125375.
PMID: 25955295 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoMaleki Vareki S et al. (2015-01-01), IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells. PLoS ONE, 10(11):e0143435.
PMID: 26579709 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKenna T et al. (2015-01-01), Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis. Genes Immun, 16(1):35-42.
PMID: 25354578 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayArnold C et al. (2015-01-01), The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses. Immunobiology, 220(1):10-9.
PMID: 25454489 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCampia I et al. (2015-01-01), An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE, 10(5):e0126159.
PMID: 25955018 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOth et al. (2014-01-01), Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells. PLoS ONE, 9(8):e103725.
PMID: 25144736 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGarcia S et al. (2014-01-01), Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype. PLoS ONE, 9(1):e82088.
PMID: 24404127 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBerri F et al. (2014-01-01), Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication. J Virol, 88(19):11215-28.
PMID: 25031344 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMacLeod A et al. (2014-01-01), Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. J Immunol, 192(12):5695-702.
PMID: 24808367 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCichocki F et al. (2014-01-01), Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency. J Exp Med, 211(6):1079-91.
PMID: 24842371 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJi et al. (2014-01-01), Identification of novel human leukocyte antigen-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy. Stem Cells Transl Med, 3(3):356-64.
PMID: 24375541 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYamashita A et al. (2014-01-01), Increased metabolite levels of glycolysis and pentose phosphate pathway in rabbit atherosclerotic arteries and hypoxic macrophage. PLoS ONE, 9(1):e86426.
PMID: 24466087 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayReiner A et al. (2014-01-01), Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189. Int J Mol Sci, 16(1):758-87.
PMID: 25561230 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVoraphani N et al. (2014-01-01), An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. Mucosal Immunol, 7(5):1175-85.
PMID: 24518246 -
Species: Human
Sample Types: Plasma
Applications: BioassayFryer et al. (2014-01-01), G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism. J Pharmacol Exp Ther, 348(3):421-31.
PMID: 24399854 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRoy S et al. (2014-01-01), CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo. J Biol Chem, 289(2):1174-82.
PMID: 24275652 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDeng B et al. (2014-01-01), Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. PLoS ONE, 9(7):e102362.
PMID: 25036362 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVermi W et al. (2014-01-01), slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells. Nat Commun, 5(0):3029.
PMID: 24398631 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFairfax B et al. (2014-01-01), Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science, 343(6175):1246949.
PMID: 24604202 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJebran A et al. (2014-01-01), Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul. PLoS Negl Trop Dis, 8(2):e2694.
PMID: 24551257 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhong H et al. (2014-01-01), Hemin controls T cell polarization in sickle cell alloimmunization. J Immunol, 193(1):102-10.
PMID: 24879794 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMilwid et al. (2014-01-01), Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators. Mol Ther, 22(5):999-1007.
PMID: 24496384 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMelhem N et al. (2014-01-01), The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8(+) T cell responses. Virology, 450(0):34-48.
PMID: 24503065 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayUhlenbrock F et al. (2014-01-01), The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway. J Immunol, 193(4):1654-65.
PMID: 25024379 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRen Z et al. (2014-01-01), E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-kappaB modulation. Mol Cancer, 13(0):84.
PMID: 24742333 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayChiricozzi et al. (2014-01-01), IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model. PLoS ONE, 9(2):e90284.
PMID: 24587313 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLiu Y et al. (2014-01-01), Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J Immunol, 192(1):59-72.
PMID: 24323580 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHu M et al. (2014-01-01), TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3. Proc Natl Acad Sci U S A, 111(4):1509-14.
PMID: 24434549 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNiedbala W et al. (2014-01-01), Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nat Commun, 5(0):4575.
PMID: 25099390 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLopez-Ramirez M et al. (2014-01-01), MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. FASEB J, 28(6):2551-65.
PMID: 24604078 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySuzuki et al. (2014-01-01), Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes. J Biol Chem, 289(8):5330-9.
PMID: 24398680 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCulina S et al. (2014-01-01), No major role for insulin-degrading enzyme in antigen presentation by MHC molecules. PLoS ONE, 9(2):e88365.
PMID: 24516642 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEngstrom A et al. (2014-01-01), Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2. Int J Oncol, 44(2):385-92.
PMID: 24296981 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWong et al. (2014-01-01), Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol, 192(8):3548-58.
PMID: 24616476 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayValle Oseguera et al. (2014-01-01), cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells. PLoS ONE, 9(2):e88708.
PMID: 24520416 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayParlato M et al. (2014-01-01), CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis. J Immunol, 192(5):2449-59.
PMID: 24501201 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassayvan Wilgenburg et al. (2014-01-01), The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PLoS ONE, 9(1):e86071.
PMID: 24465876 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJansson D et al. (2014-01-01), A role for human brain pericytes in neuroinflammation. J Neuroinflammation, 11(0):104.
PMID: 24920309 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFrazier T et al. (2014-01-01), Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions. Stem Cells Dev, 23(9):968-77.
PMID: 24405386 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShi L et al. (2014-01-01), The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS ONE, 9(5):e93846.
PMID: 24796678 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayItaliani et al. (2014-01-01), Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE, 9(2):e87680.
PMID: 24498352 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureKatholnig K et al. (2013-01-01), p38alpha senses environmental stress to control innate immune responses via mechanistic target of rapamycin. J Immunol, 190(4):1519-27.
PMID: 23315073 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIachininoto M et al. (2013-01-01), Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. Molecules, 18(9):10132-45.
PMID: 23973990 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDong J et al. (2013-01-01), Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes. Eur J Immunol, 43(3):793-804.
PMID: 23255246 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChen P et al. (2013-01-01), Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma. PLoS ONE, 8(4):e61446.
PMID: 23613854 -
Species: Human
Sample Types: Plasma
Applications: BioassayRosen L et al. (2013-01-01), Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol, 190(8):3959-66.
PMID: 23509356 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMadonna S et al. (2013-01-01), Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses. Eur J Immunol, 43(7):1883-95.
PMID: 23592500 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHambleton et al. (2013-01-01), STAT2 deficiency and susceptibility to viral illness in humans. Proc Natl Acad Sci U S A, 110(8):3053-8.
PMID: 23391734 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZizzo G et al. (2013-01-01), IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids. J Immunol, 190(10):5237-46.
PMID: 23596310 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLlop-Guevara A et al. (2013-01-01), A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure. PLoS ONE, 9(2):e88714.
PMID: 24551140 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMelo et al. (2013-01-01), The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography. PLoS ONE, 8(3):e59578.
PMID: 23555714 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBancerek J et al. (2013-01-01), CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response. Immunity, 38(2):250-62.
PMID: 23352233 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang et al. (2013-01-01), Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection. J Virol, 87(8):4372-83.
PMID: 23388728 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXia et al. (2013-01-01), Inhibition of hepatitis B virus gene expression and replication by ribonuclease P. Mol Ther, 21(5):995-1003.
PMID: 23481322 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJohnston A et al. (2013-01-01), Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis. Hum Mol Genet, 22(9):1807-15.
PMID: 23376980 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPennino D et al. (2013-01-01), IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients. J Allergy Clin Immunol, 131(2):562-70.
PMID: 23174657 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYoneno K et al. (2013-01-01), TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease. Immunology, 139(1):19-29.
PMID: 23566200 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKothari H et al. (2012-01-01), Mycobacterium tuberculosis infection and tissue factor expression in macrophages. PLoS ONE, 7(9):e45700.
PMID: 23029190 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZizzo G et al. (2012-01-01), Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction. J Immunol, 189(7):3508-20.
PMID: 22942426 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhang J et al. (2012-01-01), Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS ONE, 7(4):e34965.
PMID: 22529962 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBonanno G et al. (2012-01-01), Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma. J Transl Med, 10(0):247.
PMID: 23232072 -
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay(2012-01-01), CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates. Eur. J. Immunol., 42(8):2019-30.
PMID: 22585548 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKayali AG et al. (2012-01-01), The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells. PLoS ONE, 7(6):e38721.
PMID: 22761699 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012-01-01), Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis. J. Exp. Med., 209(11):2033-47.
PMID: 23071254 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKuriyama T et al. (2012-01-01), Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis. Blood, 120(19):4058-67.
PMID: 22990013 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012-01-01), Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts. Clin. Cancer Res., 17(9):2819-29.
PMID: 21357681 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGraham LM et al. (2012-01-01), The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase. J. Biol. Chem., 287(31):25964-74.
PMID: 22689578 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012-01-01), Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. Gene Ther, 19(10):1035-40.
PMID: 22071967 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012-01-01), Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes. J. Invest. Dermatol., 132(11):2593-600.
PMID: 22673732 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShin HS et al. (2011-01-01), Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J. Immunol., 186(2):1119-30.
PMID: 21169547 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJoubert P et al. (2011-01-01), Expression and regulation of CCL15 by human airway smooth muscle cells. Clin. Exp. Allergy, 42(1):85-94.
PMID: 22092970 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHasegawa H et al. (2011-01-01), Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein. Cytokine, 53(1):74-83.
PMID: 20926308 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGibbings S et al. (2011-01-01), Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha. J. Biol. Chem., 286(2):961-75.
PMID: 21059659 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKnoblach T et al. (2011-01-01), Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma. PLoS Pathog., 7(4):e1002016.
PMID: 21533215 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCarrier Y et al. (2011-01-01), Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis. J. Invest. Dermatol., 131(12):2428-37.
PMID: 21881584 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVon Bubnoff D et al. (2011-01-01), Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J. Immunol., 186(12):6701-9.
PMID: 21543643 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGudjonsson JE et al. (2010-01-01), Evidence for altered Wnt signaling in psoriatic skin. J. Invest. Dermatol., 130(7):1849-59.
PMID: 20376066 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGhirelli C et al. (2010-01-01), Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood, 115(24):5037-40.
PMID: 20382843 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPennino D et al. (2010-01-01), IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. J. Immunol., 184(9):4880-8.
PMID: 20357258 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMengshol JA et al. (2010-01-01), A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS ONE, 5(3):e9504.
PMID: 20209097 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhang G et al. (2010-01-01), B7-h3 augments the inflammatory response and is associated with human sepsis. J. Immunol., 185(6):3677-84.
PMID: 20696859 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMorishige T et al. (2010-01-01), Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy. Biomaterials, 31(12):3357-63.
PMID: 20117833 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKotarsky K et al. (2010-01-01), A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol, 3(1):40-8.
PMID: 19812544 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNishida A et al. (2010-01-01), Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts. Gut, 59(4):531-41.
PMID: 19996325 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGhigo E et al. (2010-01-01), IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation. PLoS ONE, 5(10):e13561.
PMID: 21042409 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySemiramoth N et al. (2009-01-01), Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. J. Leukoc. Biol., 85(2):310-21.
PMID: 19015376 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWitte K et al. (2009-01-01), Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun., 10(8):702-14.
PMID: 19798076 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee WI et al. (2009-01-01), Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease. J. Clin. Immunol., 29(3):319-29.
PMID: 19089604 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAlbanesi C et al. (2009-01-01), Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med., 206(1):249-58.
PMID: 19114666 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChristophi GP et al. (2009-01-01), Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1. Clin. Immunol., 133(1):27-44.
PMID: 19559654 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWolk K et al. (2009-01-01), The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur. J. Immunol., 39(12):3570-81.
PMID: 19830738 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKinoshita H et al. (2009-01-01), Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 123(1):179-86.
PMID: 19056108 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEid RE et al. (2009-01-01), Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 119(10):1424-32.
PMID: 19255340 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHirosako S et al. (2009-01-01), Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells. Clin. Exp. Immunol., 155(2):266-74.
PMID: 19040600 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMa P et al. (2009-01-01), Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines. Invest. Ophthalmol. Vis. Sci., 50(6):2702-9.
PMID: 19151401 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNishida A et al. (2009-01-01), Interleukin-32 expression in the pancreas. J. Biol. Chem., 284(26):17868-76.
PMID: 19386602 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRahmoun M et al. (2009-01-01), Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils. J. Invest. Dermatol., 129(3):671-81.
PMID: 18843289 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySchwinn N et al. (2009-01-01), Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells. Int. J. Cancer, 124(7):1594-604.
PMID: 19089914 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMacRedmond R et al. (2009-01-01), Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury. Eur. Respir. J., 33(6):1403-14.
PMID: 19164355 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHao Q et al. (2009-01-01), Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. Am. J. Physiol., Cell Physiol., 296(4):C821-7.
PMID: 19176759 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLiu TY et al. (2008-01-01), Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 38(4):1012-23.
PMID: 18350544 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDambacher J et al. (2008-01-01), The role of interleukin-22 in hepatitis C virus infection. Cytokine, 41(3):209-16.
PMID: 18191408 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHama S et al. (2008-01-01), Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation. Clin. Exp. Immunol., 154(3):384-90.
PMID: 19037921 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMontecucco F et al. (2008-01-01), C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. J. Leukoc. Biol., 84(4):1109-19.
PMID: 18591415 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJoubert P et al. (2008-01-01), Expression and regulation of CCR1 by airway smooth muscle cells in asthma. J. Immunol., 180(2):1268-75.
PMID: 18178867 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWente MN et al. (2008-01-01), Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. Int. J. Oncol., 33(2):297-308.
PMID: 18636150 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWolk K et al. (2008-01-01), Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes. J. Leukoc. Biol., 83(5):1181-93.
PMID: 18281438 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGuttman-Yassky E et al. (2008-01-01), Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J. Immunol., 181(10):7420-7.
PMID: 18981165 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Biancotto A et al. (2008-01-01), Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res. Hum. Retroviruses, 24(3):453-62.
PMID: 18327985 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKato A et al. (2008-01-01), Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 121(6):1385-92, 1392.
PMID: 18410958 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFacco M et al. (2007-01-01), Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. J. Leukoc. Biol., 82(4):946-55.
PMID: 17615381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWosik K et al. (2007-01-01), Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis. J. Neurosci., 27(34):9032-42.
PMID: 17715340 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Qui H et al. (2007-01-01), Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin. Chem., 53(11):2010-2.
PMID: 18030696 -
Species: Rat
Sample Types: In Vivo
Applications: In VivoParmley LA et al. (2007-01-01), Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury. Br. J. Pharmacol., 152(6):915-29.
PMID: 17828290 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDame TM et al. (2007-01-01), IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation. J. Immunol., 178(2):1172-9.
PMID: 17202382 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Biancotto A et al. (2007-01-01), Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood, 109(10):4272-9.
PMID: 17289812 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOates JC et al. (2007-01-01), Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients. Arthritis Rheum., 56(11):3738-47.
PMID: 17968874 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySa SM et al. (2007-01-01), The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol., 178(4):2229-40.
PMID: 17277128 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKanda N et al. (2007-01-01), Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. Endocrinology, 148(5):2317-25.
PMID: 17255201 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWatanabe K et al. (2007-01-01), Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. J. Biol. Chem., 282(43):31643-55.
PMID: 17720976 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDambacher J et al. (2007-01-01), Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. Gut, 56(9):1257-65.
PMID: 17449633 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNagineni CN et al. (2007-01-01), Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. J. Cell. Physiol., 210(1):192-200.
PMID: 17013806 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHundhausen C et al. (2007-01-01), Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. J. Immunol., 178(12):8064-72.
PMID: 17548644 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShioya M et al. (2007-01-01), Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease. Clin. Exp. Immunol., 149(3):480-6.
PMID: 17590175 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHajishengallis G et al. (2007-01-01), Complement receptor 3 blockade promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo. J. Immunol., 179(4):2359-67.
PMID: 17675497 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKato A et al. (2007-01-01), TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J. Immunol., 179(2):1080-7.
PMID: 17617600 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWan B et al. (2006-01-01), Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. J. Immunol., 177(12):8844-50.
PMID: 17142787 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJohnson LA et al. (2006-01-01), An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med., 203(12):2763-77.
PMID: 17116732 -
Species: Hamster
Sample Types: Whole Cells
Applications: BioassayPetropavlovskaia M et al. (2006-01-01), Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J. Endocrinol., 191(1):65-81.
PMID: 17065390 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Gounni Abdelilah S et al. (2006-01-01), Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 120(2):220-31.
PMID: 16782408 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySugaya M et al. (2006-01-01), Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. J. Immunol., 177(11):7665-72.
PMID: 17114436 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMesturini R et al. (2006-01-01), ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells. Eur. J. Immunol., 36(10):2601-12.
PMID: 17013990 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWolk K et al. (2006-01-01), IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol., 36(5):1309-23.
PMID: 16619290 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEbert EC et al. (2006-01-01), Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell. Immunol., 241(1):7-13.
PMID: 16914126 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhang Y et al. (2006-01-01), Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J. Neurosci., 26(47):12174-85.
PMID: 17122042 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySkoberne M et al. (2006-01-01), The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 108(3):947-55.
PMID: 16614246 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCho ML et al. (2006-01-01), Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol. Lett., 105(2):159-66.
PMID: 16564576 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPeng H et al. (2006-01-01), HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia, 54(6):619-29.
PMID: 16944452 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMeller S et al. (2005-01-01), Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 52(5):1504-16.
PMID: 15880822 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKermarrec N et al. (2005-01-01), Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Crit. Care Med., 33(6):1359-64.
PMID: 15942356 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayScapini P et al. (2005-01-01), Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood, 105(2):830-7.
PMID: 15358625 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDulos J et al. (2005-01-01), CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum., 52(3):770-8.
PMID: 15751070 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAmeredes BT et al. (2005-01-01), Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J. Allergy Clin. Immunol., 116(1):65-72.
PMID: 15990776 -
Best SM et al. (2005-01-01), Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol., 79(20):12828-39.
PMID: 16188985 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang P et al. (2004-01-01), Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem. J., 380(0):425-33.
PMID: 14992689 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWolk K et al. (2004-01-01), IL-22 increases the innate immunity of tissues. Immunity, 21(2):241-54.
PMID: 15308104 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRadstake TR et al. (2004-01-01), Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum., 50(12):3856-65.
PMID: 15593217 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOynebraten I et al. (2004-01-01), Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood, 104(2):314-20.
PMID: 15044249 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Copeland S et al. (2004-01-01), Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 284(1):99-106.
PMID: 14736420 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRyan LA et al. (2004-01-01), TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia. J. Neuroimmunol., 148(1):127-39.
PMID: 14975593 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGibot S et al. (2004-01-01), A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med., 200(11):1419-26.
PMID: 15557347 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPivarcsi A et al. (2004-01-01), CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. J. Immunol., 173(9):5810-7.
PMID: 15494534 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWen FQ et al. (2004-01-01), Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 30(6):816-22.
PMID: 14722222 -
Species: Human
Applications: Binding AssayUchida K et al. (2004-01-01), High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood, 103(3):1089-98.
PMID: 14512323 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKao CY et al. (2004-01-01), IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 173(5):3482-91.
PMID: 15322213 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGroh V et al. (2003-01-01), Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. U.S.A., 100(16):9452-7.
PMID: 12878725 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBorchmann P et al. (2003-01-01), The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma. Blood, 102(10):3737-42.
PMID: 12881320 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDurali D et al. (2003-01-01), In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood, 102(12):4084-9.
PMID: 12893768 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMcLoughlin RM et al. (2003-01-01), Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest., 112(4):598-607.
PMID: 12925700 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang XB et al. (2002-01-01), Expression of CTLA-4 by human monocytes. Scand. J. Immunol., 55(1):53-60.
PMID: 11841692 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMirani M et al. (2002-01-01), HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. J. Immunol., 169(11):6361-8.
PMID: 12444143 -
Species: Human
Applications: BioassayBarcena A et al. (1996-01-01), Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 88(6):2013-25.
PMID: 8822920 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang R et al. (), Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1. J Leukoc Bio91(2):299-309.
PMID: 22045868 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBabelova A et al. (), Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Che284(36):24035-48.
PMID: 19605353 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBsat M et al. (), The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages. Curr Proto1(3):e74.
PMID: 33705607
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Customer Reviews for Recombinant Human IFN-gamma Protein (22)
Customer Images
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Application: FlowVerified Customer | Posted 06/24/2022Black -> HLA-E surface expression in T cellsGrey -> HLA-E surface expression in T cells upon IFNg stimulation (12h)
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Application: In vitro bioactivity in cell cultureReason for Rating: Comparing gene expression responses by qPCR after IFNg treatment in immune cell subsetsVerified Customer | Posted 06/24/2022More than a hundred-fold increase for a given target gene in immune cells stimulated with IFNg for 6h compared to controls (for basal level).
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Reason for Rating: Used for successfully stimulating human PBMCs.Verified Customer | Posted 06/24/2022Lane 1: PBMCs, unstimulatedLane 2: PBMCs, stimulated with IFNg for 6hLane 3: PBMCs, stimulated with IFNg for 24hTarget: HLA detection
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 05/21/2021
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Application: Apoptosis assayVerified Customer | Posted 03/11/2021
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Verified Customer | Posted 12/18/2020
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Application: Stem/Immune cell maintenance or differentiationReason for Rating: Gave consistent M1-like macrophage differentiation of human PBMCsVerified Customer | Posted 11/20/2020
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Application: In vitro bioactivity in cell cultureReason for Rating: Easy to solubilizeVerified Customer | Posted 10/16/2020Used the to stimulate ex vivo skin culture
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 10/09/2020HCT-116 cells were treated with hr-IFN-gamma for 24 hours and intracellular IDO-1 expression was measured.
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 06/08/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 06/06/2020
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Application: CellProlifVerified Customer | Posted 07/26/2019
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Application: In vitro bioactivity in cell cultureReason for Rating: Consistent results when used for in vitro cell cultureVerified Customer | Posted 07/25/2019CD38 transcript levels measured by qPCR after 24 hours treatment with 10 ng/mL IFN-g in MV-4-11 cells
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Application: In vitro bioactivity in cell cultureReason for Rating: The expression of HLA-DR increased with MDAMB231 cells incubated with 1000 IU mL–1 IFN-gamma for 72 hVerified Customer | Posted 06/09/2019
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Application: Enzymatic activity in vitroVerified Customer | Posted 03/19/2019
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Application: CellProlifReason for Rating: HT-29 Cell lines were treated with 100 U/ml IFN gamma, after which HLA-DR expression was examined by flow cytometerVerified Customer | Posted 11/16/2018
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 10/08/2018
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Verified Customer | Posted 04/26/2017
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Application: In vitro bioactivity in cell cultureReason for Rating: The IFN-g was excellent in stimulating whole blood.Verified Customer | Posted 07/21/2016IFN-g was used to stimulate whole blood. 100ng/mL final concentration was used in 1mL whole blood for 15 minutes at 37C. The cells were fixed and stored in -80C until further analysis on CyTOF
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Application: In vivo studyVerified Customer | Posted 07/13/2016IFN-gamma treatment (solid line) induces HLA-DR expression in cultured MSC as compared to control cells (filled histogram).
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 05/31/2016
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 01/21/2016
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FAQs for Recombinant Human IFN-gamma Protein
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Why does Recombinant Human IFN-gamma protein, Catalog # 285-IF, have the amio acid substitution R160Q?
The sequence of R&D Systems' rhIFN-gamma, Catalog # 285-IF, is based on the the following publication in Nature:[https://www.ncbi.nlm.nih.gov/pubmed/?term=Gray+1982+503] Note that in figure 3, the article describes a Gln (Q) in position 160.