43 results for "Compounds for Induced Pluripotent Stem Cells" in Products

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Compounds for Induced Pluripotent Stem Cells

SB 431542
Catalog #: 1614
(13)
Citations (2523)
Product Documents
Images (2)

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity:
≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)
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1614/1
1614/10
1614/50
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CHIR 99021
Catalog #: 4423
(19)
Citations (2255)
Product Documents
Images (2)

Highly selective GSK-3 inhibitor; acts as Wnt activator

GMP Version Available: TB4423-GMP
GMP
Alternate Names:
CHIR99021,CT99021
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)
Catalog #
Availability
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Qty
4423/10
4423/50
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SB 431542GMP

Catalog #: TB1614-GMP
Citations (3)
Product Documents
Images (1)

SB 431542 synthesized to cGMP guidelines

Chemical Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity:
≥99%
SB 431542 synthesized to cGMP guidelines
Catalog #
Availability
Size / Price
Qty
TB1614-GMP/10
Bulk Order

3-Deazaneplanocin A hydrochloride
Catalog #: 4703
Citations (11)
Product Documents
Images (1)

EZH2 histone methyltransferase inhibitor

Alternate Names:
DZNep,NSC 617989,HY-12186
Chemical Name:
(1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride
Purity:
≥98%
EZH2 histone methyltransferase inhibitor
Catalog #
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4703/1
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CHIR 99021GMP

Catalog #: TB4423-GMP
Citations (6)
Product Documents
Images (2)

CHIR 99021 synthesized to cGMP guidelines

Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥99%
CHIR 99021 synthesized to cGMP guidelines
(2)
Catalog #
Availability
Size / Price
Qty
TB4423-GMP/10
Bulk Order

Forskolin
Catalog #: 1099
(6)
Citations (944)
Product Documents
Images (2)

Adenylyl cyclase activator

Alternate Names:
Coleonol,Colforsin
Chemical Name:
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(2)
Catalog #
Availability
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Qty
1099/50
1099/10
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A 83-01
Catalog #: 2939
(12)
Citations (1154)
Product Documents
Images (6)

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name:
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(6)
Catalog #
Availability
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2939/10
2939/50
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IWP 2
Catalog #: 3533
(3)
Citations (547)
Product Documents
Images (2)

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name:
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity:
≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)
Catalog #
Availability
Size / Price
Qty
3533/10
3533/50
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LY 294002 hydrochloride
Catalog #: 1130
(7)
Citations (111)
Product Documents
Images (1)

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name:
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride
Purity:
≥99%
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Catalog #
Availability
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1130/25
1130/5
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PD 0325901
Catalog #: 4192
(8)
Citations (388)
Product Documents
Images (1)

Potent inhibitor of MEK1/2

Alternate Names:
PD325901
Chemical Name:
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Purity:
≥99%
Potent inhibitor of MEK1/2
Catalog #
Availability
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Qty
4192/10
4192/50
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endo-IWR 1
Catalog #: 3532
Citations (71)
Product Documents
Images (1)

Wnt/β-catenin signaling inhibitor; axin stabilizer

Chemical Name:
rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Purity:
≥98%
Wnt/β-catenin signaling inhibitor; axin stabilizer
Catalog #
Availability
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Qty
3532/10
3532/50
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XAV 939
Catalog #: 3748
(1)
Citations (410)
Product Documents
Images (1)

Potent tankyrase inhibitor

GMP Version Available: TB3748-GMP
GMP
Alternate Names:
XAV939 Wnt Signaling Inhibitor
Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥98%
Potent tankyrase inhibitor
Catalog #
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3748/10
3748/50
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Pifithrin-α hydrobromide
Catalog #: 1267
(3)
Citations (14)
Product Documents
Images (1)

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Chemical Name:
1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist
Catalog #
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1267/10
1267/50
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Valproic acid, sodium salt
Catalog #: 2815
(2)
Citations (27)
Product Documents
Images (1)

Histone deacetylase inhibitor

Alternate Names:
VPA,Sodium Valproate
Chemical Name:
Sodium 2-propylpentanoate
Histone deacetylase inhibitor
Catalog #
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Qty
2815/100
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XAV 939GMP

Catalog #: TB3748-GMP
Product Documents
Images (1)

XAV 939 synthesized to cGMP guidelines

Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥99%
XAV 939 synthesized to cGMP guidelines
Catalog #
Availability
Size / Price
Qty
TB3748-GMP/10
Bulk Order

CKI 7 dihydrochloride
Catalog #: 5329
Citations (2)
Product Documents
Images (1)

CK1 inhibitor

Chemical Name:
N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
Purity:
≥99%
CK1 inhibitor
Catalog #
Availability
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5329/10
5329/50
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TTNPB
Catalog #: 0761
Citations (69)
Product Documents
Images (1)

Retinoic acid analog; RAR agonist

Alternate Names:
Ro 13-7410
Chemical Name:
4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
Purity:
≥98%
Retinoic acid analog; RAR agonist
Catalog #
Availability
Size / Price
Qty
0761/10
0761/50
Bulk Order

SANT-1
Catalog #: 1974
Citations (68)
Product Documents
Images (1)

Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity

Chemical Name:
N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
Purity:
≥98%
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
Catalog #
Availability
Size / Price
Qty
1974/10
1974/50
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Trichostatin A
Catalog #: 1406
(1)
Citations (67)
Product Documents
Images (1)

Potent histone deacetylase inhibitor

Chemical Name:
(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity:
≥95%
Potent histone deacetylase inhibitor
Catalog #
Availability
Size / Price
Qty
1406/1
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Thiazovivin
Catalog #: 3845
Citations (92)
Product Documents
Images (1)

ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Chemical Name:
N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Purity:
≥98%
ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs
Catalog #
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Qty
3845/10
Bulk Order

Sodium butyrate
Catalog #: 3850
(1)
Citations (18)
Product Documents
Images (1)

Histone deacetylase inhibitor

Chemical Name:
Butanoic acid sodium salt
Histone deacetylase inhibitor
Catalog #
Availability
Size / Price
Qty
3850/50
Bulk Order

Tranylcypromine hydrochloride
Catalog #: 3852
(2)
Citations (15)
Product Documents
Images (1)

Irreversible inhibitor of LSD1; also inhibits MAO

Alternate Names:
2-PCPA
Chemical Name:
(±)-trans-2-Phenylcyclopropylamine hydrochloride
Purity:
≥98%
Irreversible inhibitor of LSD1; also inhibits MAO
Catalog #
Availability
Size / Price
Qty
3852/50
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(±)-Bay K 8644
Catalog #: 1544
(1)
Citations (73)
Product Documents
Images (1)

CaV1.x activator

Chemical Name:
1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester
Purity:
≥98%
CaV1.x activator
Catalog #
Availability
Size / Price
Qty
1544/50
1544/10
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KY 02111
Catalog #: 4731
Citations (15)
Product Documents
Images (1)

Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

Chemical Name:
N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
Purity:
≥98%
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
Catalog #
Availability
Size / Price
Qty
4731/5
4731/25
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Polyamine Supplement x1000 (lyophilized)
Catalog #: 7739
Citations (2)
Product Documents
Images (1)

Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability

Lyophilized Polyamine Supplement x1000 | Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
Catalog #
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7739/1 Pack
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