(±)-Bay K 8644

Tocris Bioscience, part of Bio-Techne | Catalog # 1544

CaV1.x activator
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Key Product Details

Description

CaV1.x activator

View all Cav1.x Channel Activators »

Product Description

(±)-Bay K 8644 is a L-type Ca2+ channel activator (EC50 = 17.3 nM). Has positive inotropic, vasoconstrictive and behavioral effects in vivo. In combination with BIX-01294 (Cat. No. 3364), helps generate induced pluripotent stem cells (iPSCs) from mouse embryonic fibroblasts (MEFs). Inhibits autophagy.

(S)-(-)-Enantiomer and (R)-(+)-Enantiomer also available.

Product Specifications

Molecular Weight

356.30

Formula

C16H15F3N2O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester

CAS Number

71145-03-4

PubChem ID

2303

InChI Key

ZFLWDHHVRRZMEI-UHFFFAOYSA-N

SMILES

COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1C(F)(F)F)[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.63 100
Ethanol 35.63 100

Preparing Stock Solutions for (±)-Bay K 8644

The following data is based on the product molecular weight 356.30

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.81 mL 14.03 mL 28.07 mL
5 mM 0.56 mL 2.81 mL 5.61 mL
10 mM 0.28 mL 1.40 mL 2.81 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

Calculators

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Reconstitution Calculator

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Product Documents for (±)-Bay K 8644

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (±)-Bay K 8644

For research use only

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