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Forskolin

Adenylyl Cyclase Activators Small Molecule

Key Product Details

Description: Adenylyl cyclase activator
Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98% (HPLC)
Molecular Weight: 410.51

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Citations for Forskolin (86)

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Customer Reviews (6)

4.7 out of 5
6 customer ratings
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  • Works well with organoids
    Name: Gautam Kok
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Liver organoids
    Culturing liver organoids - used to swell the organoids
    Forskolin Serum 1099
  • Jurkat cells treated with Forskolin
    Name: Tahmineh Safaie
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Jurkat
    Jurkat cells were treated with different concentration of Forskolin for 15 minutes and the cAMP was measured (the cAMP levels are reversely correlated with Luminescent values.)
    Forskolin Serum 1099
  • Validation
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Sprague-Dawley rats primary neuronal
    10 μM for 30min
    Forskolin Serum 1099
  • To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 10 mM Forskolin)
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: ips
    To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 10 mM Parnate, 3 mM Chir99021, 1 mM A83-01, and 10 mM Forskolin)
    Forskolin Serum 1099
  • Forskolin increases intracellular cAMP levels
    Name: Niroj Shrestha
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK293
    HEK293 cells transfected with cAMP FRET sensor, Epac-S(H187) were perfused in normal tyrode solution and excited alternately at 430 nm and fluorescence was captured at 470 and 535 nm. Forskolin (10 µM) was added at 1 min to activate adenylyl cyclase and increase intracellular cAMP, which is detected as an increase in 470/535 fluorescence ratio.
    Forskolin Serum 1099
  • a potent adenylyl cyclase
    Name: Anonymous
    Species: Rat
    Forskolin activates adenylyl cyclase and increases intracellular cAMP. We used at 10 microM in cultured astrocytes to increase intracellular cAMP level.

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