Forskolin

Citations are publications that use Bio-Techne products. Selected citations for Forskolin include:

• Post et al. (2020) Snake venom gland organoids Cell. 180:233
  PMID: 31978343
• Segal et al. (2019) Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors. Nat Commun. 10:3350
  PMID: 31350390
• Delpiano et al. (2019) Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells. Front Pharmacol. 9:1462
  PMID: 30618754
• Sachs et al. (2019) Long-term expanding human airway organoids for disease modeling. EMBO J. 38
  PMID: 30643021
• Saito et al. (2019) Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma. Cell Rep. 27:1265
  PMID: 31018139
• Franchini et al. (2019) Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and Cognition. iScience. 19:927
  PMID: 31518901
• French et al. (2019) Dual-Mode FRET and BRET Sensors for Detecting cAMP Dynamics. ACS Omega. 4:15504
  PMID: 31572851
• Schnúr et al. (2019) Phosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia. Sci Rep. 9:12706
  PMID: 31481727
• Jewell et al. (2019) GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. Elife. 8
  PMID: 31112131
• Garcia et al. (2019) Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support. Front Neurosci. 13:669
  PMID: 31316341
• Chiu et al. (2019) NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content. Cell Rep. 28:332
  PMID: 31291571
• Cordonier et al. (2019) Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression. J Endocr Soc. 3:1246
  PMID: 31214662
• Gauster et al. (2018) Downregulation of p53 drives autophagy during human trophoblast differentiation. Cell Mol Life Sci. 75:1839
  PMID: 29080089
• Burdyga et al. (2018) Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane. Proc Natl Acad Sci U S A.. 115(28):E6497
  PMID: 29941564
• Costa et al. (2018) Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome. Front Mol Neurosci. 11:353
  PMID: 30333723
• Ford et al. (2018) A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice. Dev Cell. 47:509
  PMID: 30458140
• Patra et al. (2018) Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism. Nat Cell Biol. 20:811
  PMID: 29941929
• Noh et al. (2018) Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR. Autophagy. 14:1761
  PMID: 29969945
• Mo et al. (2018) MBD1 Contributes to the Genesis of Acute Pain and Neuropathic Pain by Epigenetic Silencing of Oprm1 and Kcna2 Genes in Primary Sensory Neurons. J Neurosci. 38:9883
  PMID: 30266739
• Liu et al. (2018) CRISPR-based chromatin remodeling of the endogenous Oct4 or Sox2 locus enables reprogramming to pluripotency. Cell Stem Cell.. 22:252
  PMID: 29358044
• Tozzi et al. (2018) DA D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson�s disease. Cell Death Dis. 9(2):204
  PMID: 29434188
• Yang et al. (2017) Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 169:243
  PMID: 28388409
• Li et al. (2017) Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics. 7:4671
  PMID: 29187895
• Luo (2017) β2-adrenoreceptor Inverse Agonist Down-regulates Muscarine Cholinergic Subtype-3 Receptor and Its Downstream Signal Pathways in Airway Smooth Muscle Cells in vitro. Scientific Reports. 7:39905
  PMID: 28051147
• Burgueño et al. (2017) A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses. Sci Rep. 7:15389
  PMID: 29133887
• Demeautis et al. (2017) Multiplexing PKA and ERK12 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM. Sci Rep. 7:41026
  PMID: 28106114
• Al-Taei et al. (2017) Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: Self-amplifying immunosuppression in cancer. Oncoimmunology. 6:e1268308
  PMID: 28344879
• Chan et al. (2016) ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of Ins signaling in an Alzheimer's disease mouse model. Cell. 6:26119
  PMID: 27189808
• Pattabiraman et al. (2016) Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 351:aad3680
  PMID: 26941323
• Havekes et al. (2016) Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. J Neurosci. 36:8936
  PMID: 27559174
• Aguileta et al. (2016) A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress. Cell Death Differ. 23:1670
  PMID: 27341185
• Avanzato et al. (2016) Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling Scientific Reports. 6:32602
  PMID: 27586846
• Siuda et al. (2015) Optodynamic simulation of β-adrenergic receptor signalling. Eneuro. 6:8480
  PMID: 26412387
• Emery et al. (2015) Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secr. Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform. J Cell Mol Med. 87:928
  PMID: 25769305
• Brzosko et al. (2015) Retroactive modulation of spike timing-dependent plasticity by DA. Elife. 4
  PMID: 26516682
• Belgacem and Borodinsky (2015) Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. Eur J Neurosci. 112:4140
  PMID: 25829542
• Elliott et al. (2015) Somatostatin and Ins mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMP. Am J Physiol Endocrinol Metab. 308:E130
  PMID: 25406263
• Muñoz-Llancao et al. (2015) Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B. Biochim Biophys Acta. 35:11315
  PMID: 26269639
• Parnell et al. (2015) Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells. Mol Metab. 1853:1749
  PMID: 25913012
• Moon et al. (2015) Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. J Biol Chem. 290:11246
  PMID: 25762723
• Li et al. (2015) Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice. Mol Pharmacol. 4:246
  PMID: 25737957
• Cooke et al. (2015) Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptor. Cell Death Dis. 172:593
  PMID: 24697554
• Polito et al. (2015) Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3). J Neurosci. 2
  PMID: 26465004
• Baron et al. (2015) The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Sci Rep. 6:e1629
  PMID: 25654762
• Ang et al. (2015) The short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytes. Ann Clin Transl Neurol. 5:8134
  PMID: 25633224
• Walker et al. (2015) A second trigeminal CGRP receptor: function and expression of the AMY1 receptor. Nat Commun. 2:595
  PMID: 26125036
• Broadbent et al. (2015) The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor. Sci Rep. 467:1783
  PMID: 25277268
• Ben-Simon et al. (2015) A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity. Pflugers Arch. 12:396
  PMID: 26166572
• Brust et al. (2015) New functional activity of aripipr. revealed: Robust antagonism of D2 DA receptor-stimulated Gβγ signaling. Cell Rep. 93:85
  PMID: 25449598
• Presley et al. (2015) Preclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist. Biochem Pharmacol. 3:e00159
  PMID: 26196013
• Zhu et al. (2015) Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways. Pharmacol Res Perspect. 35:621
  PMID: 25589756
• Jansen et al. (2015) Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. Stem Cell Reports. 19:210
  PMID: 25266063
• Muthusamy et al. (2014) A method to identify and isolate pluripotent human stem cells and mouse epiblast stem cells using lipid body-associated retinyl ester fluorescence. Stem Cell Reports. 3:169
  PMID: 25068130
• Yang et al. (2014) PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling. J Biol Chem. 66:83
  PMID: 24225179
• Chou et al. (2014) Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells. PLoS One. 9:e99432
  PMID: 24918932
• Adelfinger et al. (2014) GABAB receptor phosphorylation regulates KCTD12-induced K⁺ current desensitization. Biochem Pharmacol. 91:369
  PMID: 25065880
• Felizola et al. (2014) PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues. Glia. 52:159
  PMID: 24403568
• Waheed et al. (2014) Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a TRPP2 (polycystin-2)-dependent manner. Br J Pharmacol. 171:2659
  PMID: 24116661
• Shelton et al. (2014) Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells. Br J Pharmacol. 3:516
  PMID: 25241748
• Vandame et al. (2014) The spatio-temporal dynamics of PKA activity profile during mitosis and its correlation to chromosome segregation. Cell Cycle. 13:3232
  PMID: 25485503
• Sohn et al. (2013) Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. J Mol Endocrinol. 152:612
  PMID: 23374353
• Pale et al. (2013) Cyclic AMP stimulates neurite outgrowth of lamprey reticulospinal neurons without substantially altering their biophysical properties. Neuroscience. 245:74
  PMID: 23603516
• Wiseman et al. (2013) Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase. J Biol Chem. 288:17803
  PMID: 23640883
• Tao et al. (2013) cAMP level modulates scleral collagen remodeling, a critical step in the development of myopia. Br J Pharmacol. 8:e71441
  PMID: 23951163
• Ehrlich et al. (2013) Prostaglandin E receptor EP1 forms a complex with DA D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing G(βγ) subunits in human embryonic kidney 293T cells. Mol Pharmacol. 84:476
  PMID: 23842570
• Jia et al. (2013) Age-dependent regulation of synaptic connections by DA D2 receptors. Nat Neurosci. 16:1627
  PMID: 24121738
• Korboukh et al. (2012) Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice. J Med Chem. 55:6467
  PMID: 22738238
• Tran et al. (2012) Dynamic mass redistribution assays decode surface influence on signaling of endogenous purinergic P2Y receptors. Assay Drug Dev Technol. 10:37
  PMID: 22066912
• Hook et al. (2012) DArgic modulation of ganglion-cell photoreceptors in rat. J Neurosci. 35:507
  PMID: 22304466
• Kaufman et al. (2012) Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. J Neurosci. 32:3992
  PMID: 22442066
• Mitra et al. (2012) Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity. Nat Neurosci. 15:250
  PMID: 22179109
• Horváth et al. (2012) A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. J Neurosci. 165:2462
  PMID: 21449982
• Lee et al. (2012) The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca²⁺ and cAMP. Nature. 492:123
  PMID: 23143333
• Bolognini et al. (2012) AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor. Br J Pharmacol. 165:2561
  PMID: 21615724
• Althaus et al. (2011) Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells. Am J Respir Cell Mol Biol. 44:53
  PMID: 20139350
• Benito et al. (2011) cAMP response element-binding protein is a primary hub of activity-driven neuronal gene expression. J Neurosci. 31:18237
  PMID: 22171029
• Chen et al. (2011) Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium. J Biol Chem. 286:13502
  PMID: 21317289
• Bonetti and Surace (2010) Mouse embryonic retina delivers information controlling cortical neurogenesis. J Mol Cell Cardiol. 5:e15211
  PMID: 21170332
• Buznikov et al. (2010) A putative 'pre-nervous' endocannabinoid system in early echinoderm development. Dev Neurosci. 32:1
  PMID: 19907129
• Schapitz et al. (2010) Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci. 30:12733
  PMID: 20861378
• Garavaglia et al. (2010) Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates. BMC Neurosci. 11:7
  PMID: 20085655
• Goffin et al. (2010) DA-dependent tuning of striatal inhibitory synaptogenesis. PLoS One. 30:2935
  PMID: 20181591
• Roscioni et al. (2009) PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells. Respir Res. 10:88
  PMID: 19788733
• Byrnes et al. (2009) Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity. J Clin Invest. 57:550
  PMID: 18816644
• Rao et al. (2007) Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons. PLoS One. 117:4022
  PMID: 18060037
• Hosoi et al. (2002) Identification of a novel human eicosanoid receptor coupled to G(i/o). J Biol Chem. 277:31459
  PMID: 12065583

There are no citations that match your criteria.

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• (5)

• Works well with organoids

  Name: Gautam Kok
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Liver organoids
  Culturing liver organoids - used to swell the organoids
  

• Jurkat cells treated with Forskolin

  Name: Tahmineh Safaie
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Jurkat
  Jurkat cells were treated with different concentration of Forskolin for 15 minutes and the cAMP was measured (the cAMP levels are reversely correlated with Luminescent values.)
  

• Validation

  Name: Anonymous
  Species: Rat
  Assay Type: In Vitro
  Cell Line/Tissue: Sprague-Dawley rats primary neuronal
  10 μM for 30min
  PMID: 31291571 Reference
  

• To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 10 mM Forskolin)

  Name: Anonymous
  Species: Mouse
  Assay Type: In Vitro
  Cell Line/Tissue: ips
  To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 10 mM Parnate, 3 mM Chir99021, 1 mM A83-01, and 10 mM Forskolin)
  PMID: 29358044
  

• Forskolin increases intracellular cAMP levels

  Name: Niroj Shrestha
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: HEK293
  HEK293 cells transfected with cAMP FRET sensor, Epac-S(H187) were perfused in normal tyrode solution and excited alternately at 430 nm and fluorescence was captured at 470 and 535 nm. Forskolin (10 µM) was added at 1 min to activate adenylyl cyclase and increase intracellular cAMP, which is detected as an increase in 470/535 fluorescence ratio.
  

• a potent adenylyl cyclase

  Name: Anonymous
  Species: Rat
  Forskolin activates adenylyl cyclase and increases intracellular cAMP. We used at 10 microM in cultured astrocytes to increase intracellular cAMP level.

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