Autophagy Activators Small Molecules and Peptides

(3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate

Purity:

≥97%

Dexamethasone

Catalog #: 1126

(2)

Citations (115)

Product Documents

Images (1)

Anti-inflammatory glucocorticoid

Chemical Name:

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione

Purity:

≥98%

Rapamycin

Catalog #: 1292

(3)

Citations (386)

Product Documents

Images (1)

mTOR inhibitor; immunosuppressant

Chemical Name:

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

Purity:

≥98%

Everolimus

Catalog #: 6188

Citations (16)

Product Documents

Images (1)

mTOR inhibitor; Immunosuppressant

Alternate Names:

RAD001

Chemical Name:

42-O-(2-Hydroxyethyl)rapamycin

Purity:

≥98%

Retinoic acid

Catalog #: 0695

Citations (226)

Product Documents

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Endogenous retinoic acid receptor agonist

Alternate Names:

Tretinoin,ATRA

Chemical Name:

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid

Purity:

≥98%

Metformin hydrochloride

Catalog #: 2864

(3)

Citations (38)

Product Documents

Images (1)

Activator of LKB1/AMPK; antidiabetic agent

Chemical Name:

N,N-Dimethylimidodicarbonimidic diamide hydrochloride

Niclosamide

Catalog #: 4079

Citations (10)

Product Documents

Images (1)

STAT3 inhibitor; also inhibits mTORC1 signaling

Chemical Name:

5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

Purity:

≥98%

Carbamazepine

Catalog #: 4098

(1)

Citations (23)

Product Documents

Images (1)

Inhibitor of neuronal NaV channels; anticonvulsant

Alternate Names:

CBZ

Chemical Name:

5H-Dibenz[b,f]azepine-5-carboxamide

Purity:

≥98%

Valproic acid, sodium salt

Catalog #: 2815

(2)

Citations (27)

Product Documents

Images (1)

Histone deacetylase inhibitor

Alternate Names:

VPA,Sodium Valproate

Chemical Name:

Sodium 2-propylpentanoate

A 769662

Catalog #: 3336

Citations (123)

Product Documents

Images (1)

Potent AMPK activator

Chemical Name:

6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile

Purity:

≥98%

Tunicamycin

Catalog #: 3516

(4)

Citations (112)

Product Documents

Images (1)

Antibiotic; GlcNAc phosphotransferase inhibitor

Chemical Name:

Tunicamycin from Streptomyces sp.

Purity:

≥98%

Brefeldin A

Catalog #: 1231

(1)

Citations (98)

Product Documents

Images (1)

Disrupts protein translocation to Golgi

Chemical Name:

1,6,7,8,9,11aβ,12,13,14,14aα-Decahydro-1β,13α-dihydroxy-6β-methyl-4H-cyclopent[f]oxacyclotridecin-4-one

Purity:

≥98%

Trichostatin A

Catalog #: 1406

(1)

Citations (67)

Product Documents

Images (1)

Potent histone deacetylase inhibitor

Chemical Name:

(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide

Purity:

≥95%

Temozolomide

Catalog #: 2706

(1)

Citations (37)

Product Documents

Images (1)

DNA-methylating antitumor agent

Alternate Names:

NSC 362856,CCRG 81045

Chemical Name:

3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide

Purity:

≥98%

SAHA

Catalog #: 4652

(1)

Citations (34)

Product Documents

Images (1)

Class I and II HDAC inhibitor

Alternate Names:

Vorinostat

Chemical Name:

N-Hydroxy-N'-phenyloctanediamide

Purity:

≥98%

Torin 2

Catalog #: 4248

(1)

Citations (75)

Product Documents

Images (1)

Potent and selective mTOR inhibitor

Chemical Name:

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one

Purity:

≥98%

L-690,330

Catalog #: 0681

Citations (17)

Product Documents

Images (1)

Inositol monophosphatase inhibitor

Chemical Name:

[1-(4-Hydroxyphenoxy)ethylidene]bisphosphonic acid

Clonidine hydrochloride

Catalog #: 0690

(1)

Citations (40)

Product Documents

Images (1)

α2 agonist. Also I1 ligand

Chemical Name:

2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride

Purity:

≥98%

Nimodipine

Catalog #: 0600

(1)

Citations (206)

Product Documents

Images (1)

CaV1.x blocker

Chemical Name:

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester

Purity:

≥98%

A23187, free acid

Catalog #: 1234

(1)

Citations (9)

Product Documents

Images (1)

Calcium ionophore

Alternate Names:

Calcimycin

Chemical Name:

5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid

Purity:

≥98%