Clonidine hydrochloride
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | α2 agonist. Also I1 ligand |
Chemical Name: | 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 266.56 |
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Citations for Clonidine hydrochloride (9)
Citations are publications that use Bio-Techne products. Selected citations for Clonidine hydrochloride include:
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Harris et al.
(2018)
Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.
J Neurosci.
38:8922
PMID: 30150361 -
Devoto et al.
(2015)
Selective inhibition of DA-β-hydroxylase enhances DA release from noradrenergic terminals in the medial prefrontal cortex.
Mol Pain.
5:e00393
PMID: 26516613 -
Yuen et al.
(2014)
Synergistic regulation of glutamatergic transmission by serotonin and NE reuptake inhibitors in prefrontal cortical neurons.
J Biol Chem.
289:25177
PMID: 25056951 -
Cinelli et al.
(2013)
Suppression of the cough reflex by α 2-adrenergic receptor agonists in the rabbit.
Physiol Rep.
1:e00122
PMID: 24400133 -
Asiedu et al.
(2012)
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
J Pain.
13:546
PMID: 22537560 -
Liu et al.
(2011)
Ongoing pain in the MIA model of osteoarthritis.
Neurosci Lett.
493:72
PMID: 21241772 -
Kim et al.
(2011)
Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation.
Brain Res.
1384:110
PMID: 21315691 -
Okun et al.
(2011)
Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents.
Purinergic Signal.
7:4
PMID: 21219650 -
Garzón et al.
(2009)
Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with mor.
Mol Pain.
5:11
PMID: 19284549
There are no citations that match your criteria.
Customer Reviews for Clonidine hydrochloride (1)
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Species: RatAssay Type: In VivoBehavioral pharmacology. Systemic blockade of alpha2- noradrenergic receptors. Dissolved in water at doses of 0.01-1.0 mg/mL and injected systemically in rats. Has sedative effects on motor movement.High doses (great than 1 mg/kg) results in self-injurious behavior in rats.
There are no reviews that match your criteria.