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Tocris Bioscience a Bio-Techne Brand

SAHA | CAS No. 149647-78-9 | Class I and II HDAC inhibitor
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Key Product Details

Description: Class I and II HDAC inhibitor
Alternative Names: Vorinostat
Chemical Name: N-Hydroxy-N'-phenyloctanediamide
Purity: ≥98% (HPLC)
Molecular Weight: 264.32

Citations for SAHA (3)

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  • Excellent histone deacetylase inhibitor
    Name: Luiz Alexandre Magno
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: PC12
    Our lab uses this drug to monitor transcriptional activity of genes that depend on class I, II and IV of histone deacetylase. In the experiment shown in the figure, we have treated PC12 cells with 3 different concentrations of SAHA for 3h. We found increased transcriptional activity of PI3K gene upon SAHA treatment in a dose-dependent manner.
    SAHA can be easily resuspended in DMSO. Make a stock solution with a concentration that will not exceed 0.01% of DMSO in the cell culture to avoid toxicity.
    SAHA Serum 4652

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Product Documents for SAHA

Certificate of Analysis

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