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DNA, RNA and Protein Synthesis Compounds: Small Molecules and Peptides

25 results for "DNA, RNA and Protein Synthesis Compounds Small Molecules and Peptides" in Products

25 results for "DNA, RNA and Protein Synthesis Compounds Small Molecules and Peptides" in Products

DNA, RNA and Protein Synthesis Compounds: Small Molecules and Peptides

Non-selective protein kinase inhibitor

Alternate Names: AM-2282
Chemical Name: [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
Purity: ≥98% (HPLC)
(2)

Alkylating agent; chemotherapeutic

Chemical Name: 2-[bis(2-Chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
Purity: ≥98% (HPLC)
Alkylating agent; chemotherapeutic

RNA conformation probe; reagent for COMRADES RNA platform

Alternate Names: psoralen-triethylene glycol azide
Chemical Name: 3-(13-Azido-5,8,11-trioxa-2-azatridec-1-yl)-2,5,9-trimethyl-7H-furo[3,2-g][1]benzopyran-7-one
Purity: ≥98% (HPLC)
RNA conformation probe; reagent for COMRADES RNA platform

IKBKAP pre-mRNA splicing modulator

Chemical Name: 2-Chloro-N-(2-furanylmethyl)-7H-purin-6-amine
Purity: ≥98% (HPLC)
IKBKAP pre-mRNA splicing modulator

Selective orthosteric inhibitor of the BRCA2-RAD51 interaction

Chemical Name: N-(2-((2S,4R)-2-(((S)-1-(2-Chloro-4-methoxyphenyl)ethyl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-2-oxoethyl)-6-fluoroquinoline-2-carboxamide
Purity: ≥98% (HPLC)
Selective orthosteric inhibitor of the BRCA2-RAD51 interaction

Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise

Chemical Name: N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
Purity: ≥95% (HPLC)
Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise

Potent HTT pre-RNA splicing modulator

Chemical Name: 5-[(3R)-3-(Cyclopropylamino)-1-pyrrolidinyl]-N-(8-fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-2-pyrazinecarboxamide
Purity: ≥98% (HPLC)
Potent HTT pre-RNA splicing modulator.

Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation

Alternate Names: CP 62993
Chemical Name: 13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
Purity: ≥98% (HPLC)
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation

Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry

Chemical Name: 5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: ≥95% (HPLC)
Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry

HIV RNA splicing modulator

Chemical Name: 8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine
Purity: ≥98% (HPLC)
HIV RNA splicing modulator

Molecular glue; pre-mRNA splicing modulator

Chemical Name: N1-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
Purity: ≥98% (HPLC)
Molecular glue; pre-mRNA splicing modulator

Potent and selective herpes simplex virus (HSV) helicase primase inhibitor

Chemical Name: N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)benzeneacetamide
Purity: ≥98% (HPLC)
Potent and selective herpes simplex virus (HSV) helicase primase inhibitor

Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response

Chemical Name: 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione
Purity: ≥98% (HPLC)
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response

Photoreactive uridine analog for RNA sequencing

Chemical Name: 4-Thiouridine
Purity: ≥98% (HPLC)
Photoreactive uridine analog for RNA sequencing

Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells

Chemical Name: 2,6-Dichloro-7-(2-propyn-1-yl)-7H-purine
Purity: ≥98% (HPLC)
Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells

Hypoxia-activated DNA alkylating agent prodrug

Chemical Name: (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl N,N'-bis(2-bromoethyl)phosphorodiamidate
Applications: AdAct
Purity: ≥98% (HPLC)
Hypoxia-activated DNA alkylating agent prodrug

Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

Chemical Name: 3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid
Purity: ≥98% (HPLC)
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency

eIF4A inhibitor

Chemical Name: 2-(5-(4-Butylphenyl)furan-2-yl)-6-nitroquinoline-4-carboxylic acid
Applications: CellVia
Purity: ≥98% (HPLC)
eIF4A inhibitor

Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system

Chemical Name: α-[2-(2,4-Dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid
Purity: ≥98% (HPLC)
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system

Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

Chemical Name: 6,7-Dimethoxy-2-[((4-phenyl-3,6-dihydropyridin-1(2H)-yl)methyl)]quinazolin-4(3H)-one
Purity: ≥98% (HPLC)
Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

Synthetic thymidine analog; used for cell proliferation assays

Chemical Name: 5-Bromo-2-deoxyuridine
Purity: ≥98% (HPLC)
Synthetic thymidine analog; used for cell proliferation assays

TERT activator

Chemical Name: N-(3-Chloro-4-fluorophenyl)-4-fluoro-3,5-dimethylbenzenesulfonamide
Purity: ≥98% (HPLC)
TERT activator

Selective SMN2 gene splicing modifier

Chemical Name: 7-(4,7-Diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Purity: ≥98% (HPLC)
Selective SMN2 gene splicing modifier

Ligand for RNA aptamer AC17-4 activating gene expression in aptazime-based riboswitches

Chemical Name: N2,N4-Bis(4-fluorophenyl)-N6-(2-pyrimidinylmethyl)-1,3,5-triazine-2,4,6-triamine hemifumarate
Purity: ≥98% (HPLC)
Ligand for RNA aptamer AC17-4 activating gene expression in aptazime-based riboswitches

Potent and selective DYRK1A inhibitor

Chemical Name: 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
Purity: ≥98% (HPLC)
Potent and selective DYRK1A inhibitor
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