4-Thiouridine

Tocris Bioscience, part of Bio-Techne | Catalog # 7005

Photoreactive uridine analog for RNA sequencing
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Key Product Details

Description

Photoreactive uridine analog for RNA sequencing

View all DNA, RNA and Protein Synthesis Compounds »

Product Description

4-Thiouridine is a photoreactive uridine analog for RNA sequencing (RNA seq) and thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM seq). Used as a crosslinker to identify RNA binding proteins. Is incorporated into newly transcribed RNA and can be used to track RNA from synthesis to degradation.

Product Specifications

Molecular Weight

260.26

Formula

C9H12N2O5S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-Thiouridine

CAS Number

13957-31-8

PubChem ID

3032615

InChI Key

ZLOIGESWDJYCTF-XVFCMESISA-N

SMILES

OC[C@H]1O[C@@H](N2C=CC(NC2=O)=S)[C@@H]([C@@H]1O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 5.21 20
DMSO 5.21 20

Preparing Stock Solutions for 4-Thiouridine

The following data is based on the product molecular weight 260.26

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 19.21 mL 96.06 mL 192.12 mL
1 mM 3.84 mL 19.21 mL 38.42 mL
2 mM 1.92 mL 9.61 mL 19.21 mL
10 mM 0.38 mL 1.92 mL 3.84 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for 4-Thiouridine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 4-Thiouridine

For research use only

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