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137 results for "ROCK2" in Products

ROCK2 Products

ROCK2/II (Rho-associated protein kinase 2; also Rho-kinase alpha) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92-354), a coiled-coil region (aa 429-1131) and a zinc-finger region (aa 1260-1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids. Over aa 641-846, human ROCK2 shares 94% and 96% aa identity with mouse and canine ROCK2, respectively.

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

Alternate Names: y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor
Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity: ≥98% (HPLC)
ROCK inhibition by Y-27632 and immunostaining of skeletal myogenic differentiation of MESP1+ mesoderm,
(8)

Y-27632 synthesized to cGMP guidelines

Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity: ≥99%
Y-27632 synthesized to cGMP guidelines
Reactivity: Human, Mouse
Details: Mouse IgG1 kappa Monoclonal Clone #1E12
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: ROCK2 Antibody (1E12) [H00009475-M02]
(4)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Immunohistochemistry-Paraffin: ROCK2 Antibody [NBP1-86124]
(7)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #GT11712
Applications: IHC, WB
Western Blot: ROCK2 Antibody (GT11712) [NBP3-13535]
(8)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Mycoplasma
Immunocytochemistry/ Immunofluorescence: ROCK2 Antibody [NBP2-20199]
(6)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
Western Blot: ROCK2 Antibody [NBP2-58122]
(2)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #8G3U2
Applications: IHC, WB, ELISA
Western Blot: ROCK2 Antibody (8G3U2) [NBP3-16123]
(3)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, IP
Western Blot: ROCK2 Antibody [NB100-593]
(2)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: ROCK2 AntibodyBSA Free [NBP1-76570]
(3)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #S01-4F1
Applications: WB, ICC/IF
Western Blot: ROCK2 Antibody (S01-4F1) [NBP3-19508]
(2)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #JE31-36
Applications: IHC, WB, ICC/IF
ROCK2 Antibody (JE31-36)
(3)

Recombinant Monoclonal Antibody

Reactivity: Human
Details: Rabbit IgG Monoclonal Clone #HL1071
Applications: WB, ICC/IF
(4)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #10E1
Applications: WB, ELISA, ICC/IF
Western Blot: ROCK2 Antibody (10E1) [NBP3-15152]
(2)
Reactivity: Human
Details: Mouse IgG2b Kappa Monoclonal Clone #2A4
Applications: WB, ELISA, ICC/IF
Western Blot: ROCK2 Antibody (2A4) [H00009475-M01]
(2)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #23GB2030
Applications: WB, ICC/IF, Flow, Mycoplasma
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