Y-27632 dihydrochloride

Name: Y-27632 dihydrochloride
Brand: Tocris Bioscience
SKU: TB1254-GMP

Tocris Bioscience a Bio-Techne Brand

Catalog # TB1254-GMP

Citations (3)

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Key Product Details

Description:	Y-27632 synthesized to cGMP guidelines
Chemical Name:	trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:	≥99%
Molecular Weight:	320.26

View Full Technical Details for Y-27632 dihydrochloride

Biological Activity for Y-27632 dihydrochloride

Y-27632 dihydrochloride is a Y-27632 synthesized to cGMP guidelines. Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

For more information about how Y-27632 may be used, please see our protocols: Transdifferentiating Fibroblasts into Neurons, Converting Fibroblasts into Cardiomyocytes (9C Cocktail), Accelerated Induction of Cortical Neurons from hiPSCs, Human iPSC-derived Myoblasts.

Research use only Y-27632 also available.

Current Good Manufacturing Practice (cGMP) is a harmonized set of guidelines that when implemented will ensure safe, reliable, consistent and quality-assured products. The Tocris range of cGMP small molecules is manufactured following relevant sections of ICH Q7 guidelines. Our highly skilled team has full control over the cGMP process, meaning we can ensure: a quality-assured manufacturing system, batch-to-batch consistency, consistent supply, traceability from starting material to final product, and animal-free production. Find out more about the Tocris range of cGMP compounds.

Technical Data for Y-27632 dihydrochloride

M. Wt	320.26
Formula	C₁₄H₂₁N₃O.2HCl
Storage	Store at RT
Purity	≥99%
CAS Number	129830-38-2
InChi Key	IDDDVXIUIXWAGJ-LJDSMOQUSA-N
Smiles	N[C@H](C)[C@@]1([H])CC[C@H](C(NC2=CC=NC=C2)=O)CC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

This product is intended for research use or further manufacturing only.

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Citations for Y-27632 dihydrochloride (4)

Showing 1 - 3 of 4 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Y-27632 dihydrochloride include:

Ma et al. (2021) Generation of an iPSC line (SMCPGi001-A) from a patient with Bain type X-linked mental retardation syndrome carrying HNRNPH2 gene mutation. Stem Cell Res.. 57:102571
PMID: 34763229
Guo et al. (2021) Establishment of an induced pluripotent stem cell line (ZJSHi001-A) from a patient with epileptic encephalopathy carrying KCNB1 Glu330Asp mutation. Stem Cell Res.. 52:102224
PMID: 33607466
Gantner et al. (2020) An optimized protocol for the generation of midbrain dopamine neurons under defined conditions. STAR Protoc.. 1:100065
PMID: 33111103
Duman et al. (2019) The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. Elife. 8
PMID: 31461398

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Showing 1 - 3 of 4 citations Showing All

Product Documents for Y-27632 dihydrochloride

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.