ROCK2 Products
ROCK2/II (Rho-associated protein kinase 2; also Rho-kinase alpha) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92-354), a coiled-coil region (aa 429-1131) and a zinc-finger region (aa 1260-1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids. Over aa 641-846, human ROCK2 shares 94% and 96% aa identity with mouse and canine ROCK2, respectively.
124 results for "ROCK2" in Products
124 results for "ROCK2" in Products
ROCK2 Products
ROCK2/II (Rho-associated protein kinase 2; also Rho-kinase alpha) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92-354), a coiled-coil region (aa 429-1131) and a zinc-finger region (aa 1260-1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids. Over aa 641-846, human ROCK2 shares 94% and 96% aa identity with mouse and canine ROCK2, respectively.
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
| Alternate Names: | y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor |
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Y-27632 synthesized to cGMP guidelines
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #GT11712 |
| Applications: | IHC, WB |
![Western Blot: ROCK2 Antibody (GT11712) [NBP3-13535]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-GT11712-Western-Blot-NBP3-13535-img0007.jpg "Western Blot: ROCK2 Antibody (GT11712) [NBP3-13535]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: ROCK2 Antibody [NBP1-86124]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-Immunohistochemistry-Paraffin-NBP1-86124-img0014.jpg "Immunohistochemistry-Paraffin: ROCK2 Antibody [NBP1-86124]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Mycoplasma |
![Western Blot: ROCK2 Antibody [NBP2-20199]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-Western-Blot-NBP2-20199-img0008.jpg "Western Blot: ROCK2 Antibody [NBP2-20199]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1E12 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: ROCK2 Antibody (1E12) [H00009475-M02]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-1E12-Western-Blot-H00009475-M02-img0009.jpg "Western Blot: ROCK2 Antibody (1E12) [H00009475-M02]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK2 Antibody [NBP2-58122]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-Western-Blot-NBP2-58122-img0003.jpg "Western Blot: ROCK2 Antibody [NBP2-58122]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #8G3U2 |
| Applications: | IHC, WB, ELISA |
![Western Blot: ROCK2 Antibody (8G3U2) [NBP3-16123]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-8G3U2-Western-Blot-NBP3-16123-img0002.jpg "Western Blot: ROCK2 Antibody (8G3U2) [NBP3-16123]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: ROCK2 AntibodyBSA Free [NBP1-76570]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-Western-Blot-NBP1-76570-img0001.jpg "Western Blot: ROCK2 AntibodyBSA Free [NBP1-76570]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S01-4F1 |
| Applications: | WB, ICC/IF |
![Western Blot: ROCK2 Antibody (S01-4F1) [NBP3-19508]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-S01-4F1-Western-Blot-NBP3-19508-img0002.jpg "Western Blot: ROCK2 Antibody (S01-4F1) [NBP3-19508]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: ROCK2 Antibody [NB100-593]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-Western-Blot-NB100-593-img0006.jpg "Western Blot: ROCK2 Antibody [NB100-593]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE31-36 |
| Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #HL1071 |
| Applications: | WB, ICC/IF |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #10E1 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ROCK2 Antibody (10E1) [NBP3-15152]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-10E1-Western-Blot-NBP3-15152-img0002.jpg "Western Blot: ROCK2 Antibody (10E1) [NBP3-15152]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2A4 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ROCK2 Antibody (2A4) [H00009475-M01]](https://resources.bio-techne.com/images/products/ROCK2-Antibody-2A4-Western-Blot-H00009475-M01-img0005.jpg "Western Blot: ROCK2 Antibody (2A4) [H00009475-M01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
