Key Product Details
Description: | Inhibitor of cyclic nucleotide dependent- and Rho-kinases |
Alternative Names: | HA 1077 |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 327.83 |
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Citations for Fasudil hydrochloride (16)
Citations are publications that use Bio-Techne products. Selected citations for Fasudil hydrochloride include:
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Panciera et al.
(2020)
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogenemediated changes of cell mechanical properties.
Nat Mater.
19:797
PMID: 32066931 -
Pitha et al.
(2018)
Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma.
Transl Vis Sci Technol.
7:6
PMID: 30479877 -
Fazakas et al.
(2018)
Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.
Front Physiol.
9:537
PMID: 29867576 -
Flavahan and Flavahan
(2014)
The atypical structure and function of newborn arterial endothelium is mediated by Rho/Rho kinase signaling.
Am J Physiol Heart Circ Physiol.
307:H628
PMID: 24951756 -
Bailey et al.
(2014)
A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.
J Biol Chem.
289:30443
PMID: 25225290 -
Akhtar et al.
(2013)
Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction.
PLoS One.
8:e67813
PMID: 23826343 -
Wang et al.
(2012)
Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes.
BMC Ear Nose Throat Disord.
61:2134
PMID: 22688336 -
Jeyaraj et al.
(2012)
Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells.
Br J Pharmacol.
303:C499
PMID: 22621783 -
Lim et al.
(2012)
The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries.
PLoS One.
7:e35177
PMID: 22532844 -
Díez et al.
(2010)
STAT inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process.
PLoS One.
5:e14145
PMID: 21152444 -
Choi et al.
(2009)
Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
Diabetes.
82:324
PMID: 19218288 -
Takehara et al.
(2008)
Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells.
Mol Hum Reprod.
14:627
PMID: 18940855 -
Inan and Büyükafşar
(2008)
Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice.
J Neurosci.
155:44
PMID: 18536751 -
Rodríguez-Vita et al.
(2005)
Endothelin-1, via ETA receptor and independently of transforming growth factor-β, increases the connective tissue growth factor in vascular smooth muscle cells.
Cardiovasc Res.
97:125
PMID: 15976312 -
Scherer et al.
(2005)
Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss.
Am J Physiol Cell Physiol.
5:10
PMID: 16316469 -
Wibberley et al.
(2003)
Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle.
Br J Pharmacol.
138:757
PMID: 12642376
There are no citations that match your criteria.