
Apoptosis Inducer Compounds Products
35 results for "Apoptosis Inducer Compounds" in Products
Application
Product Action
Conjugates
Low Endotoxin
Sample Size
Citations
Reviews
Apoptosis Inducer Compounds Products
35 results for "Apoptosis Inducer Compounds" in Products
Inhibits RNA polymerase
Chemical Name : | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
Purity : | ≥95% (HPLC) |
DNA cross-linking antitumor agent
Alternate Names : | Ametycine |
Chemical Name : | [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione |
Purity : | ≥98% (HPLC) |
High affinity and selective activator of Bax
Chemical Name : | 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol |
Purity : | ≥98% (HPLC) |
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
Alternate Names : | Adriamycin, NSC 123127 |
Chemical Name : | 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione hydrochloride |
Purity : | ≥98% (HPLC) |
Potent pro-apoptotic anticancer agent; activates caspase-3
Alternate Names : | CDDP |
Chemical Name : | cis-Diaminodichloroplatinum |
DNA cross-linking antitumor agent
Alternate Names : | Eloxatin |
Chemical Name : | Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II) |
Purity : | ≥99% (HPLC) |
Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter
Alternate Names : | Kempferol |
Chemical Name : | 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Purity : | ≥98% (HPLC) |
Potent and selective MEK inhibitor; orally bioavailable
Chemical Name : | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide |
Purity : | ≥98% (HPLC) |
Suppressor of MDK expression; inhibits PI 3-K signaling
Chemical Name : | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
Purity : | ≥98% (HPLC) |
DNA cross-linking antitumor agent
Alternate Names : | NSC 241240, Paraplatin, JM 8 |
Chemical Name : | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) |
Purity : | ≥99% (HPLC) |
DNA-methylating antitumor agent
Alternate Names : | NSC 362856, CCRG 81045 |
Chemical Name : | 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide |
Purity : | ≥99% (HPLC) |
Potent fatty acid synthase inhibitor; proapoptotic
Alternate Names : | trans-C 75 |
Chemical Name : | (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid |
Purity : | ≥99% (HPLC) |
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
Chemical Name : | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
Purity : | ≥98% (HPLC) |
Pan-histone deacetylase inhibitor
Chemical Name : | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
Purity : | ≥98% (HPLC) |
Alkylating agent; chemotherapeutic
Chemical Name : | 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide |
Purity : | ≥99% (HPLC) |
Downregulates Bcl-2 and Mcl-1; pro-apoptotic
Chemical Name : | (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde |
Purity : | ≥98% (HPLC) |
Cytostatic agent; exhibits DNA alkylating and purine analog properties
Chemical Name : | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride |
Purity : | ≥98% (HPLC) |
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
Chemical Name : | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
Purity : | ≥99% (HPLC) |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
Chemical Name : | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
Purity : | ≥98% (HPLC) |
IAP and XIAP inhibitor; antitumor
Chemical Name : | 5-[(Phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol |
Purity : | ≥98% (HPLC) |
Purine analog; inhibits DNA synthesis
Chemical Name : | 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine |
Purity : | ≥99% (HPLC) |
Potent and selective HDAC8 inhibitor
Chemical Name : | N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide |
Purity : | ≥98% (HPLC) |
Selectively induces cancer cell apoptosis
Chemical Name : | 2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol hydrochloride |
Purity : | ≥99% (HPLC) |
Deoxyadenosine analog; pro-apoptotic
Alternate Names : | 2-Chloro-2'-deoxyadenosine |
Chemical Name : | (2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxalan-3-ol |
Purity : | ≥99% (HPLC) |
ULK inhibitor
Chemical Name : | N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride |
Purity : | ≥98% (HPLC) |