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Apoptosis Inducer Compounds Products
35 results for "Apoptosis Inducer Compounds" in Products
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Apoptosis Inducer Compounds Products
35 results for "Apoptosis Inducer Compounds" in Products
Inhibits RNA polymerase
| Chemical Name : | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity : | ≥95% (HPLC) |
DNA cross-linking antitumor agent
| Alternate Names : | Ametycine |
| Chemical Name : | [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione |
| Purity : | ≥98% (HPLC) |
Catalog #:
5314
High affinity and selective activator of Bax
| Chemical Name : | 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol |
| Purity : | ≥98% (HPLC) |
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
| Alternate Names : | Adriamycin, NSC 123127 |
| Chemical Name : | 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione hydrochloride |
| Purity : | ≥98% (HPLC) |
Potent pro-apoptotic anticancer agent; activates caspase-3
| Alternate Names : | CDDP |
| Chemical Name : | cis-Diaminodichloroplatinum |
DNA cross-linking antitumor agent
| Alternate Names : | Eloxatin |
| Chemical Name : | Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II) |
| Purity : | ≥99% (HPLC) |
Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter
| Alternate Names : | Kempferol |
| Chemical Name : | 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Purity : | ≥98% (HPLC) |
Catalog #:
7709
Potent and selective MEK inhibitor; orally bioavailable
| Chemical Name : | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide |
| Purity : | ≥98% (HPLC) |
Catalog #:
5126
Suppressor of MDK expression; inhibits PI 3-K signaling
| Chemical Name : | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
| Purity : | ≥98% (HPLC) |
DNA cross-linking antitumor agent
| Alternate Names : | NSC 241240, Paraplatin, JM 8 |
| Chemical Name : | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II) |
| Purity : | ≥99% (HPLC) |
DNA-methylating antitumor agent
| Alternate Names : | NSC 362856, CCRG 81045 |
| Chemical Name : | 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide |
| Purity : | ≥99% (HPLC) |
Potent fatty acid synthase inhibitor; proapoptotic
| Alternate Names : | trans-C 75 |
| Chemical Name : | (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid |
| Purity : | ≥99% (HPLC) |
Catalog #:
6835
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name : | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
Catalog #:
7629
Pan-histone deacetylase inhibitor
| Chemical Name : | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity : | ≥98% (HPLC) |
Catalog #:
4091
Alkylating agent; chemotherapeutic
| Chemical Name : | 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide |
| Purity : | ≥99% (HPLC) |
Downregulates Bcl-2 and Mcl-1; pro-apoptotic
| Chemical Name : | (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde |
| Purity : | ≥98% (HPLC) |
Cytostatic agent; exhibits DNA alkylating and purine analog properties
| Chemical Name : | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid hydrochloride |
| Purity : | ≥98% (HPLC) |
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
| Chemical Name : | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Purity : | ≥99% (HPLC) |
Catalog #:
7680
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name : | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity : | ≥98% (HPLC) |
IAP and XIAP inhibitor; antitumor
| Chemical Name : | 5-[(Phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol |
| Purity : | ≥98% (HPLC) |
Purine analog; inhibits DNA synthesis
| Chemical Name : | 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine |
| Purity : | ≥99% (HPLC) |
Potent and selective HDAC8 inhibitor
| Chemical Name : | N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide |
| Purity : | ≥98% (HPLC) |
Catalog #:
2137
Selectively induces cancer cell apoptosis
| Chemical Name : | 2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol hydrochloride |
| Purity : | ≥99% (HPLC) |
Deoxyadenosine analog; pro-apoptotic
| Alternate Names : | 2-Chloro-2'-deoxyadenosine |
| Chemical Name : | (2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxalan-3-ol |
| Purity : | ≥99% (HPLC) |
Catalog #:
5780
ULK inhibitor
| Chemical Name : | N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride |
| Purity : | ≥98% (HPLC) |
