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15 results for "Apoptosis Inducer Compounds" in Products

Apoptosis Inducer Compounds

Antitumor antibiotic agent. Inhibits DNA topoisomerase II

Alternate Names:
Adriamycin,NSC 123127
Chemical Name:
10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione hydrochloride
Purity:
≥98%
Doxorubicin treated cardiomyocytes secrete Troponin T
(3)

Inhibits RNA polymerase

Chemical Name:
2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Purity:
≥95%
Inhibits RNA polymerase

Purine analog; inhibits DNA synthesis

Chemical Name:
9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine
Purity:
≥98%
Purine analog; inhibits DNA synthesis

Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

Chemical Name:
4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide
Purity:
≥97%
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis

Alternate Names:
NSC125066
Purity:
≥90%
DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis

Potent fatty acid synthase inhibitor; proapoptotic

Alternate Names:
trans-C 75
Chemical Name:
(2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid
Purity:
≥94%
Potent fatty acid synthase inhibitor; proapoptotic

Potent and selective HDAC8 inhibitor

Chemical Name:
N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide
Purity:
≥98%
Potent and selective HDAC8 inhibitor

ULK inhibitor

Chemical Name:
N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride
Purity:
≥98%
ULK inhibitor

Inhibitor of SLC39A7 (ZIP7) zinc transporter; induces apoptosis and inhibits ferroptosis.

Chemical Name:
1-[(2S)-2-[(6-Fluoro-2-benzothiazolyl)amino]-3-phenylpropyl]-spiro[piperidine-4,4'(1'H)-quinazolin]-2'(3'H)-one
Purity:
≥98%
Inhibitor of SLC39A7 (ZIP7) zinc transporter; induces apoptosis and inhibits ferroptosis.

Pan-histone deacetylase inhibitor

Chemical Name:
(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
Purity:
≥98%
Pan-histone deacetylase inhibitor

Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis

Chemical Name:
6-[8-[(2-Benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylic acid
Purity:
≥98%
Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis

High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Chemical Name:
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Purity:
≥98%
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Potent and selective MEK inhibitor; orally bioavailable

Chemical Name:
N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide
Purity:
≥98%
Potent and selective MEK inhibitor; orally bioavailable

Potent pan-HDAC inhibitor

Chemical Name:
(2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide
Purity:
≥98%
Potent pan-HDAC inhibitor

Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming

Alternate Names:
Silmitasertib
Chemical Name:
Sodium 5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylate
Purity:
≥98%
Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming
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