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Voltage-gated Sodium Channel Blockers: Small Molecules and Peptides
25 results for "Voltage-gated Sodium Channel Blockers Small Molecules and Peptides" in Products
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Voltage-gated Sodium Channel Blockers: Small Molecules and Peptides
25 results for "Voltage-gated Sodium Channel Blockers Small Molecules and Peptides" in Products
Na+ channel blocker
| Chemical Name : | 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide |
| Purity : | ≥99% (HPLC) |
Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078)
| Alternate Names : | TTx citrate |
| Chemical Name : | (4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol citrate |
| Purity : | ≥98% (HPLC) |
Na+ channel blocker
| Alternate Names : | TTx |
| Chemical Name : | (4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol |
| Purity : | ≥98% (HPLC) |
Potent and selective NaV1.8 channel blocker; active in vivo
| Chemical Name : | 1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine |
| Purity : | ≥98% (HPLC) |
Potent and selective Nav1.7 channel blocker
| Chemical Name : | 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate |
| Purity : | ≥98% (HPLC) |
Na+ channel blocker
| Chemical Name : | N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride |
| Purity : | ≥99% (HPLC) |
Potent and selective Nav1.7 blocker; analgesic
| Chemical Name : | 4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide |
| Purity : | ≥98% (HPLC) |
Na+ channel blocker; also I2 imidazoline ligand
| Chemical Name : | 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride |
| Purity : | ≥98% (HPLC) |
NaV channel blocker
| Chemical Name : | N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide |
| Purity : | ≥99% (HPLC) |
Cardiac Na+ channel blocker. Antiarrhythmic
| Chemical Name : | N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate |
| Purity : | ≥99% (HPLC) |
Potent and selective Nav1.6 channel blocker
| Alternate Names : | 4,9-anhydro-TTX |
| Chemical Name : | (4S,5aS,6S,8R,9S,10S,11S,11aR,12R)-2-Amino-1,4,5a,6,8,9,10,11-octahydro-9-(hydroxymethyl)-6,10-epoxy-4,8,11a-metheno-11aH-oxocino[4,3-f][1,3,5]oxadiazepine-6,9,11-triol |
| Purity : | ≥98% (HPLC) |
Na+ channel blocker; antiarrhythmic agent
| Alternate Names : | Ko 1173 |
| Chemical Name : | 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride |
| Purity : | ≥99% (HPLC) |
Selective NaV1.7 channel blocker
| Purity : | ≥95% (HPLC) |
Na+ channel blocker
| Chemical Name : | N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide |
| Purity : | ≥99% (HPLC) |
NaV blocker; neuroprotective
| Alternate Names : | 619C89 |
| Chemical Name : | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine |
| Purity : | ≥99% (HPLC) |
Potent and selective NaV1.3 and NaV1.1 channel blocker
| Chemical Name : | α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide |
| Purity : | ≥98% (HPLC) |
Potent voltage-dependent NaV1.8 channel blocker
| Chemical Name : | 5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl-3-pyridine carboxamide |
| Purity : | ≥97% (HPLC) |
Selective Nav1.7 channel blocker
| Chemical Name : | 2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide |
| Purity : | ≥98% (HPLC) |
Photoswitchable Nav, Kv and Cav channel blocker
| Chemical Name : | 2,2'-[1,2-Diazenediylbis(4,1-phenyleneimino)bis[N,N,N-triethyl-2-oxo-ethanaminium] dichloride |
| Purity : | ≥98% (HPLC) |
Selective NaV1.8 channel blocker
| Chemical Name : | 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide |
| Purity : | ≥98% (HPLC) |
ASIC blocker; active in vivo
| Chemical Name : | 8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime |
Potent hNav1.4, rNav1.6 and rNav1.7 channel activator
| Purity : | ≥95% (HPLC) |
GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels
| Chemical Name : | 2-Amino-6-trifluoromethoxybenzothiazole hydrochloride |
| Purity : | ≥98% (HPLC) |
