Key Product Details
Description: | Na+ channel blocker |
Chemical Name: | N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 343.31 |
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Citations for QX 314 bromide (32)
Citations are publications that use Bio-Techne products. Selected citations for QX 314 bromide include:
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He et al.
(2020)
Nucleus Accumbens Tac1-Expressing Neurons Mediate Stress-Induced Anhedonia-like Behavior in Mice
Cell rep.
33
PMID: 33147466 -
Spoljaric et al.
(2019)
KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice.
Cell Rep.
26:1073
PMID: 30699338 -
Li et al.
(2019)
TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala.
Elife.
8
PMID: 31482844 -
Purkey et al.
(2018)
AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca2+-Permeable AMPA Receptors to Control LTP.
Cell Rep.
25:974
PMID: 30355502 -
Ferrarese et al.
(2018)
Dendrite-Specific Amplification of Weak Synaptic Input during Network Activity In Vivo.
Cell Rep.
24:3455
PMID: 30257207 -
Acuña et al.
(2016)
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.
J Clin Invest.
126:2547
PMID: 27270175 -
Sametsky et al.
(2015)
Enhanced GABAA-Mediated Tonic Inhibition in Auditory Thalamus of Rats with Behavioral Evidence of Tinnitus.
J Neurosci.
35:9369
PMID: 26109660 -
Xue et al.
(2015)
Structural elements that underlie Doc2β function during asynchronous synaptic transmission.
Proc Natl Acad Sci U S A.
112:E4316
PMID: 26195798 -
McGee et al.
(2015)
Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function.
J Neurosci.
35:16171
PMID: 26658868 -
Puranam et al.
(2015)
Disruption of Fgf13 causes synaptic excitatory-inhibitory imbalance and genetic epilepsy and febrile seizures plus.
Korean J Physiol Pharmacol.
35:8866
PMID: 26063919 -
Ahn et al.
(2015)
Characteristics of K(+) Outward Currents in the Cochlear Outer Hair Cells of Circling Mice within the First Postnatal Week.
PLoS One.
19:383
PMID: 26170743 -
Lench et al.
(2015)
Differential Effects of D-Cycloserine and ACBC at NMDA Receptors in the Rat Entorhinal Cortex Are Related to Efficacy at the Co-Agonist Binding Site.
Toxins (Basel).
10:e0133548
PMID: 26193112 -
Chen and Chesler
(2015)
Autocrine boost of NMDAR current in hippocampal CA1 pyramidal neurons by a PMCA-dependent, perisynaptic, extracellular pH shift.
J Neurosci.
35:873
PMID: 25609607 -
Dale et al.
(2014)
Vort. disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus.
J Psychopharmacol.
28:891
PMID: 25122043 -
Gaffaney et al.
(2014)
Mutations that disrupt Ca2+-binding activity endow Doc2β with novel functional properties during synaptic transmission.
Mol Biol Cell.
25:481
PMID: 24356452 -
Chuhma et al.
(2014)
DA neurons control striatal cholinergic neurons via regionally heterogeneous DA and glutamate signaling.
Proc Natl Acad Sci U S A.
81:901
PMID: 24559678 -
He and Bausch
(2014)
Synaptic plasticity in glutamatergic and GABAergic neurotransmission following chronic Mem. treatment in an in vitro model of limbic epileptogenesis.
BMC Neurosci.
77:379
PMID: 24184417 -
He et al.
(2013)
Synaptic and extrasynaptic plasticity in glutamatergic circuits involving dentate granule cells following chronic N-MthD.-aspartate receptor inhibition.
J Neurosci.
109:1535
PMID: 23255721 -
Egawa et al.
(2013)
Optogenetic probing and manipulation of the calyx-type presynaptic terminal in the embryonic chick ciliary ganglion.
PLoS One.
8:e59179
PMID: 23555628 -
Wu et al.
(2013)
Ovarian hormone loss impairs excitatory synaptic transmission at hippocampal CA3-CA1 synapses.
J Neurosci.
33:16158
PMID: 24107948 -
Lerner et al.
(2010)
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.
J Neurosci.
30:2160
PMID: 20147543 -
Toyoda et al.
(2009)
Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex.
Mol Pain.
5:46
PMID: 19664265 -
Kuroyanagi et al.
(2009)
Postsynaptic glutamate receptor δ family contributes to presynaptic terminal differentiation and establishment of synaptic transmission.
J Neurophysiol.
106:4912
PMID: 19258455 -
Zhang et al.
(2009)
Tamox. mediated estrogen receptor activation protects against early impairment of hippocampal neuron excitability in an oxygen/glucose deprivation brain slice ischemia model.
Brain Res.
1247:196
PMID: 18992727 -
Hong et al.
(2008)
Glutamatergic transmission is sustained at a later period of development of medial nucleus of the trapezoid body-lateral superior olive synapses in circling mice.
J Neurosci.
28:13003
PMID: 19036993 -
Zhang et al.
(2008)
Resveratrol attenuates early pyramidal neuron excitability impairment and death in acute rat hippocampal slices caused by oxygen-glucose deprivation.
Exp Neurol.
212:44
PMID: 18495119 -
Baldelli et al.
(2007)
Lack of synapsin I reduces the readily releasable pool of synaptic vesicles at central inhibitory synapses.
J Neurosci.
27:13520
PMID: 18057210 -
Toyoda et al.
(2007)
Requirement of extracellular signal-regulated kinase/mitogen-activated protein kinase for long-term potentiation in adult mouse anterior cingulate cortex.
Mol Pain.
3:36
PMID: 18053155 -
Gipson and Yeckel
(2007)
Coincident glutamatergic and cholinergic inputs transiently depress glutamate release at rat schaffer collateral synapses.
J Neurophysiol.
97:4108
PMID: 17303811 -
Xu et al.
(2006)
Presynaptic regulation of the inhibitory transmission by GluR5-containing kainate receptors in spinal substantia gelatinosa.
Mol Pain.
2:29
PMID: 16948848 -
Linnemann et al.
(2006)
Transient change in GABA(A) receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration.
Neuron.
7:59
PMID: 16872511 -
Sur et al.
(2003)
N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-MthD.-aspartate receptor activity.
Proc Natl Acad Sci U S A.
100:13674
PMID: 14595031
There are no citations that match your criteria.
Customer Reviews for QX 314 bromide (1)
Customer Images
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Species: RatAssay Type: In VitroCell Line/Tissue: HippocampusQX-314 was used to block voltage-gated sodium channels, i.e. prevent action potential propagation. The compound develops its effect in 1 microM concentration, in use-dependent mode. Figure: EPSC evoked by electrical stimulation in hippocampal pyramidal neuron at positive membrane potential (+40 mV); QX-314 is added to intracellular solution.
There are no reviews that match your criteria.