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QX 314 bromide

Voltage-gated Sodium Channel Blockers Small Molecule
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Key Product Details

Description: Na+ channel blocker
Chemical Name: N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide
Purity: ≥99% (HPLC)
Molecular Weight: 343.31

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  • QX-314 bromide blocks action potentials propagation
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Hippocampus
    QX-314 was used to block voltage-gated sodium channels, i.e. prevent action potential propagation. The compound develops its effect in 1 microM concentration, in use-dependent mode. Figure: EPSC evoked by electrical stimulation in hippocampal pyramidal neuron at positive membrane potential (+40 mV); QX-314 is added to intracellular solution.
    QX 314 bromide Serum 1014

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