Small Molecules and Peptides (19)
Small Molecules (16)
Peptides (3)
Blocker (19)
5 (5)
4 & up (8)
Tocris Bioscience (19)
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19 results for "Voltage-gated Sodium Channel Blockers Small Molecules and Peptides" in Products

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Voltage-gated Sodium Channel Blockers Small Molecules and Peptides

Tetrodotoxin
Catalog #: 1078
(5)
Citations (2010)
Product Documents
Images (1)

Na+ channel blocker

Alternate Names:
TTx
Chemical Name:
(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol
Purity:
≥98%
Na+ channel blocker
Catalog #
Availability
Size / Price
Qty
1078/1
Bulk Order

QX 314 bromide
Catalog #: 1014
(1)
Citations (86)
Product Documents
Images (1)

Na+ channel blocker

Chemical Name:
N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide
Purity:
≥98%
Na+ channel blocker
Catalog #
Availability
Size / Price
Qty
1014/100
Bulk Order

A 887826
Catalog #: 4249
Citations (7)
Product Documents
Images (1)

Potent voltage-dependent NaV1.8 channel blocker

Chemical Name:
5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl-3-pyridine carboxamide
Purity:
≥97%
Potent voltage-dependent NaV1.8 channel blocker
Catalog #
Availability
Size / Price
Qty
4249/50
4249/10
Bulk Order

Tetrodotoxin citrate
Catalog #: 1069
(3)
Citations (533)
Product Documents
Images (1)

Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078)

Alternate Names:
TTx citrate
Chemical Name:
(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol citrate
Purity:
≥98%
Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078)
Catalog #
Availability
Size / Price
Qty
1069/1
Bulk Order

Amiloride hydrochloride
Catalog #: 0890
(2)
Citations (18)
Product Documents
Images (1)

Na+ channel blocker; also I2 imidazoline ligand

Chemical Name:
3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride
Purity:
≥98%
Na+ channel blocker; also I2 imidazoline ligand
Catalog #
Availability
Size / Price
Qty
0890/100
Bulk Order

A 803467
Catalog #: 2976
Citations (36)
Product Documents
Images (1)

Selective NaV1.8 channel blocker

Chemical Name:
5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide
Purity:
≥98%
Selective NaV1.8 channel blocker
Catalog #
Availability
Size / Price
Qty
2976/10
2976/50
Bulk Order

Flecainide acetate
Catalog #: 1470
Citations (3)
Product Documents
Images (1)

Cardiac Na+ channel blocker. Antiarrhythmic

Chemical Name:
N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
Purity:
≥98%
Cardiac Na+ channel blocker. Antiarrhythmic
Catalog #
Availability
Size / Price
Qty
1470/10
1470/50
Bulk Order

QX 314 chloride
Catalog #: 2313
(3)
Citations (96)
Product Documents
Images (1)

Na+ channel blocker

Chemical Name:
N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride
Purity:
≥98%
Na+ channel blocker
Catalog #
Availability
Size / Price
Qty
2313/50
Bulk Order

TC-N 1752
Catalog #: 4435
Citations (3)
Product Documents
Images (1)

NaV channel blocker

Chemical Name:
N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
Purity:
≥98%
NaV channel blocker
Catalog #
Availability
Size / Price
Qty
4435/10
4435/50
Bulk Order

APETx2
Catalog #: 4804
Citations (6)
Product Documents
Images (1)

ASIC3 channel blocker

Purity:
≥95%
ASIC3 channel blocker
Catalog #
Availability
Size / Price
Qty
4804/100U
Bulk Order

Jingzhaotoxin III
Catalog #: 4913
Citations (1)
Product Documents
Images (1)

Selective NaV1.5 channel blocker

Purity:
≥95%
Selective NaV1.5 channel blocker
Catalog #
Availability
Size / Price
Qty
4913/100U
Bulk Order

ICA 121431
Catalog #: 5066
Citations (18)
Product Documents
Images (1)

Potent and selective NaV1.3 and NaV1.1 channel blocker

Chemical Name:
α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide
Purity:
≥98%
Potent and selective NaV1.3 and NaV1.1 channel blocker
Catalog #
Availability
Size / Price
Qty
5066/50
5066/10
Bulk Order

Lidocaine
Catalog #: 3057
(1)
Citations (49)
Product Documents
Images (1)

Na+ channel blocker

Chemical Name:
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Purity:
≥98%
Na+ channel blocker
Catalog #
Availability
Size / Price
Qty
3057/10
3057/50
Bulk Order

PF 04885614
Catalog #: 4916
(1)
Citations (2)
Product Documents
Images (1)

Potent and selective NaV1.8 channel blocker; active in vivo

Chemical Name:
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
Purity:
≥98%
Potent and selective NaV1.8 channel blocker; active in vivo
Catalog #
Availability
Size / Price
Qty
4916/10
Bulk Order

Mexiletine hydrochloride
Catalog #: 2596
Citations (4)
Product Documents
Images (1)

Na+ channel blocker; antiarrhythmic agent

Alternate Names:
Ko 1173
Chemical Name:
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Purity:
≥98%
Na+ channel blocker; antiarrhythmic agent
Catalog #
Availability
Size / Price
Qty
2596/50
Bulk Order

ProTx II
Catalog #: 4023
Citations (20)
Product Documents
Images (1)

Selective NaV1.7 channel blocker

Purity:
≥95%
Selective NaV1.7 channel blocker
Catalog #
Availability
Size / Price
Qty
4023/100U
Bulk Order

Sipatrigine
Catalog #: 4044
Citations (1)
Product Documents
Images (1)

NaV blocker; neuroprotective

Alternate Names:
619C89
Chemical Name:
2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
Purity:
≥98%
NaV blocker; neuroprotective
Catalog #
Availability
Size / Price
Qty
4044/50
4044/10
Bulk Order

PF 05089771
Catalog #: 5931
(1)
Citations (18)
Product Documents
Images (1)

Potent and selective Nav1.7 channel blocker

Chemical Name:
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate
Purity:
≥98%
Potent and selective Nav1.7 channel blocker
Catalog #
Availability
Size / Price
Qty
5931/50
5931/10
Bulk Order

PF 05089771
Catalog #: 5931
(1)
Citations (18)
Product Documents
Images (1)

Potent and selective Nav1.7 channel blocker

Chemical Name:
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate
Purity:
≥98%
Potent and selective Nav1.7 channel blocker
Catalog #
Availability
Size / Price
Qty
5931/50
5931/10
Bulk Order
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