Lidocaine

Name: Lidocaine
Brand: Tocris Bioscience
SKU: 3057
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3057

(1)

Citations (42)

COA / SDS

Na+ channel blocker

Key Product Details

Description:	Na⁺ channel blocker
Chemical Name:	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Purity:	≥99% (HPLC)
Molecular Weight:	234.34

View Full Technical Details for Lidocaine

Technical Data
Citations / Reviews (1)

Biological Activity for Lidocaine

Lidocaine is an anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.

Technical Data for Lidocaine

M. Wt	234.34
Formula	C₁₄H₂₂N₂O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	137-58-6
PubChem ID	3676
InChi Key	NNJVILVZKWQKPM-UHFFFAOYSA-N
Smiles	O=C(CN(CC)CC)NC1=C(C)C=CC=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Lidocaine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	23.43	100
	DMSO	23.43	100

Preparing Stock Solutions for Lidocaine

The following data is based on the product molecular weight 234.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.27 mL	21.34 mL	42.67 mL
5 mM	0.85 mL	4.27 mL	8.53 mL
10 mM	0.43 mL	2.13 mL	4.27 mL
50 mM	0.09 mL	0.43 mL	0.85 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Lidocaine

References are publications that support the biological activity of the product.

Sarraf Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats. Br.J.Pharmacol. 2003 PMID: 12922925