Tetrodotoxin

Citations are publications that use Bio-Techne products. Selected citations for Tetrodotoxin include:

• Maldonado et al. (2021) Oxytocin Shapes Spontaneous Activity Patterns in the Developing Visual Cortex by Activating Somatostatin Interneurons. Curr Biol. 31:322
  PMID: 33157028
• Sabater et al. (2021) Voltage-gated potassium channels ensure action potential shape fidelity in distal axons. J Neurosci. 41:5372
  PMID: 34001627
• O'Malley et al. (2020) TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations J Neurosci. 40:4813
  PMID: 32414784
• Kramer et al. (2020) Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release. ELIfe. 9
  PMID: 32870779
• Evans et al. (2020) Functional Dissection of Basal Ganglia Inhibitory Inputs onto Substantia Nigra Dopaminergic Neurons. Cell Rep. 32
  PMID: 32937133
• Dorst et al. (2020) Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner. Nat Commun. 11:5113
  PMID: 33037215
• Hui et al. (2019) GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABAA receptor trafficking and social behavior. Sci Adv. 5:eaau8237
  PMID: 30989111
• Zhu et al. (2019) Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription. Nat Commun. 10:3469
  PMID: 31375688
• Roesler et al. (2019) Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization. Front Cell Neurosci. 13:330
  PMID: 31474830
• Yu et al. (2019) Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice. Mol Brain. 12:29
  PMID: 30935412
• Romanos et al. (2019) Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Commun Biol. 2:127
  PMID: 30963115
• Ciappelloni et al. (2019) Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease. Cell Rep. 27:3860
  PMID: 31242419
• Huang et al. (2019) Neural mechanisms of contextual modulation in the retinal direction selective circuit. Nat Commun. 10:2431
  PMID: 31160566
• Rhee et al. (2019) An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 27:2212
  PMID: 31091457
• Rizzi and Tan (2019) Synergistic Nigral Output Pathways Shape Movement. Cell Rep. 27:2184
  PMID: 31091455
• Pierrot et al. (2019) Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life Sci Alliance. 2
  PMID: 30894406
• Ye et al. (2019) KA metabolite (2R,6R)-hydroxynorKA enhances aggression via periaqueductal gray glutamatergic transmission. Neuropharmacology. 157
  PMID: 31207251
• Nam et al. (2019) Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference. Cell Rep. 28:1154
  PMID: 31365861
• Green and Thayer et al. (2019) HIV gp120 upregulates tonic inhibition through α5-containing GABA_ARs. Neuropharmacology. 149:161
  PMID: 30797029
• Shen et al. (2019) Structures of human Na_v1.7 channel in complex with auxiliary subunits and animal toxins. Science. 363:1303
  PMID: 30765606
• Bülow et al. (2019) Homeostatic Intrinsic Plasticity Is Functionally Altered in Fmr1 KO Cortical Neurons. Cell Rep. 26:1378
  PMID: 30726724
• Chiu et al. (2019) NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content. Cell Rep. 28:332
  PMID: 31291571
• Smith et al. (2018) Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons. Cell Rep. 25:278
  PMID: 30304668
• Sun et al. (2018) OXT Relieves Neuropathic Pain Through GABA Release and Presynaptic TRPV1 Inhibition in Spinal Cord. Front Mol Neurosci. 11:248
  PMID: 30065629
• Zhang et al. (2018) Pauses in Cholinergic Interneuron Activity Are Driven by Excitatory Input and Delayed Rectification, with DA Modulation. Neuron. 98:918
  PMID: 29754751
• Zhong et al. (2018) Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex. J Neurosci. 38:10454
  PMID: 30355624
• Incontro (2018) The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms. Nat Commun. 9:2069
  PMID: 29802289
• Purkey et al. (2018) AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca²⁺-Permeable AMPA Receptors to Control LTP. Cell Rep. 25:974
  PMID: 30355502
• Fan et al. (2018) All-optical synaptic electrophysiology probes mechanism of KA-induced disinhibition. Nat Methods. 15:823
  PMID: 30275587
• Li et al. (2018) Hypothalamic Circuits for Predation and Evasion. Neuron. 97:911
  PMID: 29398361
• Fernandez-Fernandez et al. (2018) Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons. PLoS One. 13:e0199282
  PMID: 29928032
• Beas et al. (2018) The locus coeruleus drives disinhibition in the midline thalamus via a dopaminergic mechanism. Nat Neurosci. 21:963
  PMID: 29915192
• Saxton et al. (2018) Role of Sympathetic Nerves and Adipocyte Catecholamine Uptake in the Vasorelaxant Function of Perivascular Adipose Tissue. Arterioscler Thromb Vasc Biol. 38:880
  PMID: 29496660
• Filipello et al. (2018) The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity. Immunity. 48:979
  PMID: 29752066
• Sándor et al. (2018) Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles. Front Pharmacol. 9:323
  PMID: 29681854
• Klapper et al. (2017) On-demand optogenetic activation of human stem-cell-derived neurons. Sci Rep. 7:14450
  PMID: 29089561
• Temkin et al. (2017) The Retromer Supports AMPA Receptor Trafficking During LTP. Neuron. 94:74
  PMID: 28384478
• Nagendran et al. (2017) Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling. Nat Commun. 8:625
  PMID: 28931811
• Hashimotodani et al. (2017) LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance. Neuron. 95:928
  PMID: 28817805
• Chang et al. (2017) CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca²⁺ Signals during LTP Induction, but Not Maintenance. Neuron. 94:800
  PMID: 28521133
• Grochowska et al. (2017) Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO Rep. 18:962
  PMID: 28420656
• Teotia et al. (2017) A Co-culture Model for Determining the Target Specificity of the de novo Generated Retinal Ganglion Cells. Bio Protoc. 7
  PMID: 28660235
• Paul et al. (2017) Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Cell. 171:522
  PMID: 28942923
• Bellono (2017) Molecular basis of ancestral vertebrate electroreception. Nature. 543:391
  PMID: 28264196
• Basu et al. (2017) Heterophilic Type II Cadherins Are Required for High-Magnitude Synaptic Potentiation in the Hippocampus. Neuron. 96:160
  PMID: 28957665
• Zhao et al. (2017) A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. Neuron. 95:138
  PMID: 28625488
• Bas-Orth et al. (2017) Synaptic Activity Drives a Genomic Program That Promotes a Neuronal Warburg Effect. J Biol Chem. 292:5183
  PMID: 28196867
• Leal et al. (2017) The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons. Eneuro. 4
  PMID: 29255796
• Liu et al. (2017) IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning. Neuron. 95:106
  PMID: 28683263
• Zhang and Lu (2017) Src homology 2 domain-containing phosphotyrosine phosphatase 2 (Shp2) controls surface GluA1 protein in synaptic homeostasis. J Biol Chem. 292:15481
  PMID: 28768764
• Chen (2017) Methylene blue inhibits GABAA receptors by interaction with GABA binding site. Neuropharmacology. 119:100
  PMID: 28390894
• Tuesta (2017) GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 20(5):708
  PMID: 28368384
• Guntupalli et al. (2017) GluA1 subunit ubiquitination mediates amyloid-β-induced loss of surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. J Biol Chem. 292:8186
  PMID: 28377502
• McKeithan et al. (2017) An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Front Physiol. 8:766
  PMID: 29075196
• Sigler et al. (2017) Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release. Neuron. 94:304
  PMID: 28426965
• Wei et al. (2017) Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions. Sci Rep. 7:981
  PMID: 28428622
• Lai et al. (2017) Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. Neuron. 95:591
  PMID: 28772123
• Pollak et al. (2017) Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy. PLoS One. 12:e0172884
  PMID: 28264064
• Wang et al. (2017) Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism. J Clin Invest. 127:1978
  PMID: 28414301
• Oberlander (2016) 17β-OE Acutely Potentiates Glutamatergic Synaptic Transmission in the Hippocampus through Distinct Mechanisms in Males and Females. J Neurosci. 36:2677
  PMID: 26937008
• Savell et al. (2016) Extra-coding RNAs regulate neuronal DNA methylation dynamics. Nat Commun. 7:12091
  PMID: 27384705
• Whitt et al. (2016) BK channel inactivation gates daytime excitability in the circadian clock. Nat Commun. 7:10837
  PMID: 26940770
• Karaki et al. (2016) Effects of ε-viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa. Physiol Rep. 4
  PMID: 27162263
• Havekes et al. (2016) Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. J Neurosci. 36:8936
  PMID: 27559174
• Borgs et al. (2016) Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects Scientific Reports. 6:33377
  PMID: 27640816
• Wevers et al. (2016) High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform. Sci Rep. 6:38856
  PMID: 27934939
• Gray and Golowasch (2016) Voltage Dependence of a Neuromodulator-Activated Ionic Current. Eneuro. 3
  PMID: 27257619
• Beckley et al. (2016) The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens DA D1 Receptor Neurons. J Neurosci. 36:701
  PMID: 26791202
• Prigge et al. (2016) M1 ipRGCs Influence Visual Function through Retrograde Signaling in the Retina The Journal of Neuroscience. 6:7184
  PMID: 27383593
• Zhang et al. (2016) Increased Activity of Src Homology 2 Domain Containing Phosphotyrosine Phosphatase 2 (Shp2) Regulates Activity-dependent AMPA Receptor Trafficking. J Biol Chem. 291:18856
  PMID: 27417137
• Borgs et al. (2016) DArgic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports. 6:33377
  PMID: 27640816
• Selten et al. (2016) Increased GABA_B receptor signaling in a rat model for schizophrenia. Scientific Reports. 6:34240
  PMID: 27687783
• Mauger et al. (2016) Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity. Neuron. 92:1266
  PMID: 28009274
• Mazzaro et al. (2016) Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy. J Neurosci. 36:2086
  PMID: 26888921
• Di Castro et al. (2016) The chemokine CXCL16 modulates neurotransmitter release in hippocampal CA1 area. Scientific Reports. 6:34633
  PMID: 27721466
• Fan et al. (2016) Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Front Cell Neurosci. 10:74
  PMID: 27047338
• Miyamoto et al. (2016) Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity. PLoS Pathog. 291:1719
  PMID: 26589795
• Colavita et al. (2016) Layer-specific potentiation of network GABAergic inhibition in the CA1 area of the hippocampus. Sci Rep. 6:28454
  PMID: 27345695
• Vidal et al. (2016) Cell-Autonomous Regulation of Dendritic Spine Density by PirB. Eneuro. 3
  PMID: 27752542
• Campbell et al. (2015) Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia. J Neurosci. 8:425
  PMID: 25565960
• Stephen et al. (2015) Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling. Nat Commun. 35:15996
  PMID: 26631479
• Puranam et al. (2015) Disruption of Fgf13 causes synaptic excitatory-inhibitory imbalance and genetic epilepsy and febrile seizures plus. Mol Brain. 35:8866
  PMID: 26063919
• Lee et al. (2015) N-MthD.-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity. J Neurosci. 8:4
  PMID: 25599691
• Ganley et al. (2015) Inhibitory Interneurons That Express GFP in the PrP-GFP Mouse Spinal Cord Are Morphologically Heterogeneous, Innervated by Several Classes of Primary Afferent and Include Lamina I Projection Neurons among Their Postsynaptic Targets. Front Synaptic Neurosci. 35:7626
  PMID: 25972186
• Born et al. (2015) Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors. Mol Brain. 7:3
  PMID: 25745399
• Scudder and Patrick (2015) Synaptic structure and function are altered by the neddylation inhibitor MLN4924. Mol Cell Neurosci. 65:52
  PMID: 25701678
• Pál et al. (2015) Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity. Front Cell Neurosci. 8:35
  PMID: 26043770
• Deidda et al. (2015) Early depolarizing GABA controls critical-period plasticity in the rat visual cortex. J Neurosci. 18:87
  PMID: 25485756
• Ifrim et al. (2015) Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome. Nat Neurosci. 35:7116
  PMID: 25948262
• Zhang et al. (2015) Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity. J Neurosci. 6:8888
  PMID: 26586091
• Sobieski et al. (2015) Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro. J Neurosci. 35:11105
  PMID: 26245971
• Gao et al. (2015) Dendritic morphology, synaptic transmission, and activity of mature granule cells born following PilC-induced status epilepticus in the rat. J Neurosci. 9:384
  PMID: 26500490
• Pisano et al. (2015) Combination of miRNA499 and miRNA133 exerts a synergic effect on cardiac differentiation. Biomed Res Int. 33:1187
  PMID: 25534971
• Elgueta et al. (2015) Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells. Physiol Rep. 9:6
  PMID: 25709566
• Cuthbert et al. (2015) Neural control of submucosal gland and apical membrane secretions in airways. Oncotarget. 3
  PMID: 26059031
• Witts et al. (2015) Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice. PLoS One. 114:2305
  PMID: 26311185
• Svalø et al. (2015) Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction. J Neurosci. 10:e0117350
  PMID: 25692982
• Bernard and Zhang (2015) MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. Eur J Neurosci. 10:e0124816
  PMID: 25932647
• Savtchenko et al. (2015) Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity. PLoS One. 6:6597
  PMID: 25798861
• Feng et al. (2015) Experimental and computational evidence for an essential role of NaV1.6 in spike initiation at stretch-sensitive colorectal afferent endings. J Neurophysiol. 113:2618
  PMID: 25652923
• Glykys and Staley (2015) D.pam effect during early neonatal development correlates with neuronal Cl(.). J Cell Sci. 2:1055
  PMID: 26734658
• Morini et al. (2015) Subventricular zone neural progenitors reverse TNF-α effects in cortical neurons. Front Cell Neurosci. 6:166
  PMID: 26345473
• Yang et al. (2015) The Shaping of Two Distinct Dendritic Spikes by A-Type Voltage-Gated K(+) Channels. Ann Clin Transl Neurol. 9:469
  PMID: 26696828
• Nguyen et al. (2015) Biological Activities of Tetrodotoxin-Producing Enterococcus faecium AD1 Isolated from Puffer Fishes. Front Cell Neurosci. 2015:973235
  PMID: 26380310
• Tang et al. (2015) Modulation of AMPA receptor mediated current by nicotinic acetylcholine receptor in layer I neurons of rat prefrontal cortex. Stem Cells. 5:14099
  PMID: 26370265
• Zhong et al. (2015) BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain DA neurons. J Neurosci. 35:4469
  PMID: 25762688
• Laprell et al. (2015) Optical control of NMDA receptors with a diffusible photoswitch. Sci Rep. 6:8076
  PMID: 26311290
• Virsolvy et al. (2015) Antagonism of Nav channels and α1-adrenergic receptors contributes to vascular smooth muscle effects of ranol. Nat Commun. 5:17969
  PMID: 26655634
• Sivakumaran et al. (2015) Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo. Nat Commun. 35:8291
  PMID: 26019342
• Eyo et al. (2015) Modulation of microglial process convergence toward neuronal dendrites by extracellular calcium. J Neurosci. 35:2417
  PMID: 25673836
• Wiemhoefer et al. (2015) Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. Mol Cell Proteomics. 14:2177
  PMID: 26041847
• Torper et al. (2015) In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry. J Neurosci. 12:474
  PMID: 26166567
• Ghosh et al. (2015) NE Modulates Pyramidal Cell Synaptic Properties in the Anterior Piriform Cortex of Mice: Age-Dependent Effects of β-adrenoceptors. Cell Rep. 9:450
  PMID: 26635530
• Hooks et al. (2015) Dual-channel circuit mapping reveals sensorimotor convergence in the primary motor cortex. Front Cell Neurosci. 35:4418
  PMID: 25762684
• Erlandson et al. (2015) The Functional Organization of Neocortical Networks Investigated in Slices with Local Field Recordings and Laser Scanning Photostimulation. J Neurosci. 10:e0132008
  PMID: 26134668
• Wang et al. (2015) Protein kinase C-dependent growth-associated protein 43 phosphorylation regulates gephyrin aggregation at developing GABAergic synapses. PLoS One. 35:1712
  PMID: 25755278
• Cramer et al. (2015) Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. Mol Cell Biol. 35:5664
  PMID: 25855180
• Chen et al. (2015) Inhibitory effects of endomorphin-2 on excitatory synaptic transmission and the neuronal excitability of sacral parasympathetic preganglionic neurons in young rats. J Neurosci. 9:206
  PMID: 26074773
• Saunders et al. (2015) Corelease of acetylcholine and GABA from cholinergic forebrain neurons. Sci Rep. 4
  PMID: 25723967
• Kano et al. (2015) Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Stem Cell Res Ther. 15:138
  PMID: 25732146
• Kirwan et al. (2015) Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro. Proc Natl Acad Sci U S A. 142:3178
  PMID: 26395144
• Jang et al. (2015) Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity. Mol Brain. 8:55
  PMID: 26391783
• Speed et al. (2015) Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits. J Neurosci. 35:9648
  PMID: 26134648
• Xue et al. (2015) Structural elements that underlie Doc2β function during asynchronous synaptic transmission. Proc Natl Acad Sci U S A. 112:E4316
  PMID: 26195798
• Salvitti et al. (2015) No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida). Toxins (Basel). 7:255
  PMID: 25635464
• Astorga et al. (2015) An excitatory GABA loop operating in vivo. Front Cell Neurosci. 9:275
  PMID: 26236197
• Cao et al. (2015) Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons. Mar Drugs. 13:903
  PMID: 25675001
• Noh et al. (2015) ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons. Proc Natl Acad Sci U S A. 112:6820
  PMID: 25538301
• Tang et al. (2015) Stimulation-evoked Ca²⁺ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP. J Neurosci. 35:3016
  PMID: 25698739
• Bryant et al. (2015) Cholinergic control of γ power in the midbrain spatial attention network. Mol Brain. 35:761
  PMID: 25589769
• Asano et al. (2015) Optogenetic induction of contractile ability in immature C2C12 myotubes. Curr Mol Med. 5:8317
  PMID: 25661648
• Lin et al. (2015) Spexin Enhances Bowel Movement through Activating L-type Voltage-dependent Calcium Channel via Galanin Receptor 2 in Mice. Sci Rep. 5:12095
  PMID: 26160593
• Vossel et al. (2015) Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β. Elife. 209:419
  PMID: 25963821
• Scharinger et al. (2015) Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain. J Cell Biol. 9:309
  PMID: 26379493
• Wu et al. (2015) Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex. Front Cell Neurosci. 22:94
  PMID: 26494028
• Hou et al. (2015) MicroRNA miR124 is required for the expression of homeostatic synaptic plasticity. Nat Commun. 6:10045
  PMID: 26620774
• Park et al. (2015) Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. J Biomed Sci. 8:7
  PMID: 25645137
• Gaffaney et al. (2014) Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission. Mol Biol Cell. 25:481
  PMID: 24356452
• Cheadle and Biederer (2014) Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1. J Neurophysiol. 34:7999
  PMID: 24899721
• Tang et al. (2014) Lactate-mediated glia-neuronal signalling in the mammalian brain. Nat Commun. 5:3284
  PMID: 24518663
• Chen et al. (2014) Activation of mGluR2/3 underlies the effects of N-acetylcystein on amygdala-associated autism-like phenotypes in a valproate-induced rat model of autism. Cereb Cortex. 8:219
  PMID: 24987341
• Khor et al. (2014) Investigating diet as the source of tetrodotoxin in Pleurobranchaea maculata. Mar Drugs. 12:1
  PMID: 24368566
• Kim and Ziff (2014) Calcineurin mediates synaptic scaling via synaptic trafficking of Ca²⁺-permeable AMPA receptors. PLoS Biol. 12:e1001900
  PMID: 24983627
• Tabarean (2014) Electrical remodeling of preoptic GABAergic neurons involves the Kv1.5 subunit. Proc Natl Acad Sci U S A. 9:e96643
  PMID: 24797243
• Jiang and Zsombok (2014) Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1. Front Neurosci. 7:270
  PMID: 24454277
• Wang et al. (2014) Innervation of enteric mast cells by primary spinal afferents in guinea pig and human small intestine. Am J Physiol Gastrointest Liver Physiol. 307:G719
  PMID: 25147231
• Sakhi et al. (2014) Daily variation in the electrophysiological activity of mouse medial habenula neurones. J Physiol. 592:587
  PMID: 24247982
• Thomazeau et al. (2014) Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a. J Neurosci. 34:1138
  PMID: 24453307
• Mohn et al. (2014) Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mol Psychiatry. 19:1133
  PMID: 24934177
• Varodayan and Harrison (2014) HSF1 transcriptional activity mediates alcohol induction of Vamp2 expression and GABA release. J Neurosci. 7:89
  PMID: 24376402
• Seluzicki et al. (2014) Dual PDF signaling pathways reset clocks via TIMELESS and acutely excite target neurons to control circadian behavior. PLoS Biol. 12:e1001810
  PMID: 24643294
• Surguy et al. (2014) The actions of Pasteurella multocida toxin on neuronal cells. J Neurosci. 77:43344
  PMID: 24055502
• Wilcox et al. (2014) Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission. Neuropsychopharmacology. 39:579
  PMID: 23995582
• Klapoetke et al. (2014) Independent optical excitation of distinct neural populations. Nat Methods. 11:338
  PMID: 24509633
• Verstegen et al. (2014) Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses. J Neurosci. 34:7266
  PMID: 24849359
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• (4)

• Totally blocked action potential

  Name: Yuyang Sun
  Species: Mouse
  Assay Type: In Vitro
  Works great. Totally blocked the action potential in mouse brain slice.
  

• Validation

  Name: Anonymous
  Species: Rat
  Assay Type: In Vitro
  Cell Line/Tissue: Sprague-Dawley rats primary neuronal
  10 μM for 30min
  PMID: 31291571 Reference
  

• The pharmacological inhibitors for electrophysiology assay

  Name: Anonymous
  Species: Other
  Assay Type: In Vitro
  The following concentrations we were used:1 μM Bay K, 10 μM nifedipine, 10 μM nimodipine, 300 nM omega -agatoxin, 1 μM omega -conotoxin, 5 μM mibefradil, 1 μM tetrodotoxin, 1 μM charybdotoxin, 100 nM iberiotoxin, 10 μM NS11021.
  PMID: 28264196
  

• TTX blocks action potential propagation

  Name: Anonymous
  Species: Rat
  Assay Type: Ex Vivo
  Cell Line/Tissue: Hippocampus
  Tetrodotoxin (TTX) was used to block action potential propagation in response to lasting current injection into living neuron. This illustrated a critical role of voltage-gated sodium channels in inter-neuronal crosstalk. 1 microM of TTX developed 100% effect (see Figure). Figure: action potential generation by isolated neuron under control and after TTX was added to perfusion solution.
  Compound should be sonicated when dissolved.
  PMID: PMC6487928
  

• good drug for neuronal activity inhibition

  Name: Lihua Wang
  Species: Mouse
  Assay Type: In Vitro
  We use this to block cell activity of the brain slices, in order to keep the cells more healthy after they are dissociated. It works great and helps a lot for our purpose; but the only little problem is that it's very hard to dissolve in the water.

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