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QX 314 chloride

Tocris Bioscience a Bio-Techne Brand

Voltage-gated Sodium Channel Blockers Small Molecule
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Key Product Details

Description: Na+ channel blocker
Chemical Name: N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride
Purity: ≥99% (HPLC)
Molecular Weight: 298.85

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Citations for QX 314 chloride (9)

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Customer Reviews for QX 314 chloride (2)

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  • Whole cell recordings with blocked action potentials
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    In whole cell electrophysiology experiments, we include this in our internal solution to block voltage gated sodium channels. Typically, we use 5-30 mM. Blockade is use-dependent. Drug needs some time and activity to be more effective. Picture is of a putative evoked EPSC in a cell held at +40mV with Qx-314 in internal solution.
    QX 314 chloride Serum 2313
  • QX314+capsaicin blocks c fiber activities
    Name: Jing Feng
    Species: Mouse
    Assay Type: In Vivo
    QX314 was used to block the activities of TRPV1-positive fibers in AEW-induced chronic itch model
    QX314 should be injected with capsaicin.QX314: 200ug/mouseCapsaicin: 0.1%
    QX 314 chloride Serum 2313

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Product Documents for QX 314 chloride

Certificate of Analysis

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