Key Product Details
Description: | GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels |
Chemical Name: | 2-Amino-6-trifluoromethoxybenzothiazole hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 270.66 |
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Citations for Riluzole hydrochloride (15)
Citations are publications that use Bio-Techne products. Selected citations for Riluzole hydrochloride include:
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Zhang et al.
(2018)
Pauses in Cholinergic Interneuron Activity Are Driven by Excitatory Input and Delayed Rectification, with DA Modulation.
Neuron.
98:918
PMID: 29754751 -
Shin et al.
(2018)
Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo.
Oncogenesis.
7:86
PMID: 30425240 -
Sexton et al.
(2018)
Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer.
Sci Rep.
8:16008
PMID: 30375476 -
Dolfi et al.
(2017)
R.zole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells.
Oncotarget.
8:44639
PMID: 28591718 -
Sperling et al.
(2017)
Riluzole: a potential therapeutic intervention in human brain tumor stem-like cells.
Oncotarget.
8:96697
PMID: 29228563 -
Du et al.
(2015)
Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells.
Nat Commun.
6:6626
PMID: 25806427 -
Rosenberg et al.
(2015)
Targeting Glutamatergic Signaling and the PI3 Kinase Pathway to Halt Melanoma Progression.
Front Neural Circuits.
8:42614
PMID: 25749171 -
Du et al.
(2015)
Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells.
Nat.Commun..
6:6626
PMID: 25806427 -
Veettil et al.
(2014)
Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.
PLoS Pathog.
10:e1004389
PMID: 25299066 -
Viemari et al.
(2013)
β-Noradrenergic receptor activation specifically modulates the generation of sighs in vivo and in vitro.
Neurochem Int.
7:179
PMID: 24273495 -
Park et al.
(2013)
Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neurons.
J Neurophysiol.
109:1378
PMID: 23236005 -
Carbone et al.
(2012)
R.zole elevates GLT-1 activity and levels in striatal astrocytes.
BMC Neurosci.
60:42613
PMID: 22080156 -
Carbone et al.
(2012)
R.zole neuroprotection in a Parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation.
Cells.
13:38
PMID: 22480308 -
Le et al.
(2010)
The glutamate release inhibitor R.zole decreases migration, invasion, and proliferation of melanoma cells.
J Invest Dermatol.
130:2240
PMID: 20505744 -
Morgado-Valle et al.
(2010)
Glycinergic pacemaker neurons in preBötzinger complex of neonatal mouse.
J Neurosci.
30:3634
PMID: 20219997
There are no citations that match your criteria.