Group I mGluR Antagonists

Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Potent and selective group I mGlu antagonist

Selective non-competitive mGlu1 antagonist

Highly potent, mGlu1-selective non-competitive antagonist

Competitive group I mGlu antagonist; also weak group II agonist

Potent group I mGlu antagonist

Selective mGlu1a antagonist

mGlu1 inverse agonist

Group I mGlu antagonist

Potent and selective mGlu5 antagonist

Non-selective mGlu antagonist

Selective mGlu1 antagonist

Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)

Potent and selective mGlu5 antagonist; brain penetrant

mGlu5 antagonist; orally bioavailable and brain penetrant