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LY 456236 hydrochloride

Tocris Bioscience a Bio-Techne Brand

Group I mGluR Antagonists Small Molecule
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Key Product Details

Description: Selective mGlu1 antagonist
Alternative Names: MPMQ hydrochloride
Chemical Name: 6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride
Purity: ≥99% (HPLC)
Molecular Weight: 317.77

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  • Action via NMDA receptors
    Name: Sergiy Sylantyev
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Hippocampus
    1 microM LY 456236 was tested on action potentials generated by current injection into CA3 hippocampal neuron. Application of LY increased significantly a number of action potentials. This effect disappeared after partial block of NMDA receptors. Illustration: control recording of action potentials (top) and recording with LY 456236 (bottom).
    Can be easily diluted, no problem with long-time storage in aliquots.
    LY 456236 hydrochloride Serum 2390

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Product Documents for LY 456236 hydrochloride

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