(S)-MCPG

Citations are publications that use Bio-Techne products. Selected citations for (S)-MCPG include:

• Gu et al. (2015) miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun. 6:6789
  PMID: 25858512
• Szokol et al. (2015) Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy. Elife. 9:49
  PMID: 25762896
• Rosa et al. (2015) Neuron-glia signaling in developing retina mediated by neurotransmitter spillover. J Neurosci. 4
  PMID: 26274565
• Stephen et al. (2015) Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling. Proc Natl Acad Sci U S A. 35:15996
  PMID: 26631479
• Nieus et al. (2014) Regulation of output spike patterns by phasic inhibition in cerebellar granule cells. Front Cell Neurosci. 8:246
  PMID: 25202237
• Navarrete et al. (2012) Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol. 10:e1001259
  PMID: 22347811
• Akerboom et al. (2012) Optimization of a GCaMP calcium indicator for neural activity imaging. J Neurosci. 32:13819
  PMID: 23035093
• Platt et al. (2012) Striatal DA transmission is subtly modified in human A53Tα-synuclein overexpressing mice. PLoS One. 7:e36397
  PMID: 22570709
• Ali (2011) CB1 modulation of temporally distinct synaptic facilitation among local circuit interneurons mediated by N-type calcium channels in CA1. J Neurophysiol. 105:1051
  PMID: 21123660
• Shinoda et al. (2010) Persistent synapse loss induced by repetitive LTD in developing rat hippocampal neurons. PLoS One. 5:e10390
  PMID: 20436928
• Reissner et al. (2010) A novel postsynaptic mechanism for heterosynaptic sharing of short-term plasticity. J Neurosci. 30:8797
  PMID: 20592201
• Huang and Hsu (2010) Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 20:982
  PMID: 19666830
• Bagayogo and Dreyfus (2009) Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway. ASN Neuro. 1
  PMID: 19570026
• Fukunaga et al. (2007) Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br J Pharmacol. 151:870
  PMID: 17502847
• Bender et al. (2006) Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex. J Neurosci. 26:4166
  PMID: 16624937
• Melyan et al. (2004) Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. J Neurosci. 24:4530
  PMID: 15140923
• Melis et al. (2004) Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in DA neurons. J Neurosci. 24:10707
  PMID: 15564588
• Kumar and Foster (2004) Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores. J Neurophysiol. 91:2437
  PMID: 14762159
• Paladini et al. (2003) DA controls the firing pattern of DA neurons via a network feedback mechanism. Nat Neurosci. 100:2866
  PMID: 12604788
• Matthies et al. (2000) Enhancement of glutamate release by L-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. Learn Mem. 7:227
  PMID: 10940323
• Vogt and Nicoll (1999) Glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus. Proc Natl Acad Sci U S A. 96:1118
  PMID: 9927703
• Dunaevsky et al. (1999) Developmental regulation of spine motility in the mammalian central nervous system. Proc Natl Acad Sci U S A. 96:13438
  PMID: 10557339
• Min et al. (1999) Synaptically released glutamate reduces gamma-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors. Proc Natl Acad Sci U S A. 96:9932
  PMID: 10449797
• Colwell et al. (1996) Regulation of N-MthD.-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors? Front Cell Neurosci. 93:1200
  PMID: 8577740

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• (S)-MCPG as a blocker of mGluR action

  Name: Sergiy Sylantyev
  Species: Rat
  Assay Type: In Vitro
  Cell Line/Tissue: Hippocampus
  When mGluRs were suppressed with 1 mM (S)-MCPG, NMDAR effect was not enough powerful to generate action potentials in response to repetitive electrical stimulation of neural tissue. Figure: evoked post-synaptic potentials with action potentials (under control) and without action potentials (after application of MCPG.
  PMID: 23395378
  

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