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Group I mGluR Antagonists Small Molecule

Key Product Details

Description: Non-selective mGlu antagonist
Chemical Name: (RS)-α-Methyl-4-carboxyphenylglycine
Purity: ≥99% (HPLC)

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Citations (12)

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  • Suppression of mGluRs activated by glutamate application
    Name: Sergiy Sylantyev | 15th Oct 2020
    Species: Human
    Cell Line/Tissue: Stem cell - derived neurons
    (RS)-MCPG was in use to prevent contamination of NMDA-receptor – generated response to prolonged application of glutamate with (possible) impact from metabotropic glutamate receptors (mGluRs). APV, applied after glutamate and glycine, fully suppressed NMDA-receptor response, thus suggesting no input from mGluRs (see illustration). MCPG works as expected, but takes quite a long time to dissolve for stock preparation.
    Suppression of mGluRs activated by glutamate application Serum 0336

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