Potent and selective mGlu5 antagonist
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Key Product Details
Description: | Potent and selective mGlu5 antagonist |
Chemical Name: | 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine hydrochloride |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 236.72 |
Citations for MTEP hydrochloride (11)
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Citations are publications that use Bio-Techne products. Selected citations for MTEP hydrochloride include:
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Lim et al.
(2018)
Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures.
Int J Mol Sci.
19
PMID: 30274399 -
Thomson et al.
(2017)
Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome.
Neuron.
95:550
PMID: 28772121 -
Arsenault et al.
(2015)
Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS.
PLoS One.
10:e0142093
PMID: 26536027 -
Reissner et al.
(2015)
Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement.
Elife.
20:316
PMID: 24612076 -
Rosa et al.
(2015)
Neuron-glia signaling in developing retina mediated by neurotransmitter spillover.
Mol Brain.
4
PMID: 26274565 -
Guimaraes et al.
(2015)
The metabotropic glutamate receptor 5 role on motor behavior involves specific neural substrates.
Cell Death Dis.
8:24
PMID: 25885370 -
Pollard et al.
(2014)
Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator.
J Psychopharmacol.
28:935
PMID: 25031220 -
Jurgens et al.
(2012)
Optogenetic stimulation of the corticothalamic pathway affects relay cells and GABAergic neurons differently in the mouse visual thalamus.
PLoS One.
7:e45717
PMID: 23029198 -
Ren et al.
(2012)
Intrathecal injection of metabotropic glutamate receptor subtype 3 and 5 agonist/antagonist attenuates bone cancer pain by inhibition of spinal astrocyte activation in a mouse model.
Anesthesiology.
116:122
PMID: 22123524 -
Sumislawski et al.
(2011)
Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation.
Neuropsychopharmacology.
36:2750
PMID: 21849983 -
Tronson et al.
(2010)
Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear.
Addict Biol.
68:1007
PMID: 21075228
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