
CX3CL1/Fractalkine Products
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
68 results for "CX3CL1/Fractalkine" in Products
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CX3CL1/Fractalkine Products
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
68 results for "CX3CL1/Fractalkine" in Products
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies
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Contains 4 membranes - each spotted in duplicate with 25 different chemokine antibodies
Contains 4 membranes - each spotted in duplicate with 29 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Source : | NS0 |
Accession # : | P78423 |
Applications : | Bioactivity |
Simple Plex Human CX3CL1/Fractalkine assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Sensitivity : | 0.072 ng/mL |
Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Human Milk) |
Applications : | ELISA |
Assay Range : | 0.625 - 20 ng/mL |
Applications : | ELISA |
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Sensitivity : | 0.32 ng/mL |
Assay Range : | 0.62 - 40 ng/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #126315 |
Applications : | Block/Neutralize, ELISA Capture, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |
Source : | Sf 21 (baculovirus) |
Accession # : | O35188 |
Applications : | Bioactivity |
Source : | E. coli |
Accession # : | Q6I9S9 |
Applications : | Bioactivity |
Source : | Sf 21 (baculovirus) |
Accession # : | O55145 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #51637 |
Applications : | Flow Cytometry |
Assay Range : | 0.391 - 25 ng/mL |
Applications : | ELISA |
Assay Range : | 195 - 12,500 pg/mL |
Applications : | ELISA |
Biotinylated
Source : | HEK293 |
Accession # : | P78423.1 |
Applications : | Binding Activity, Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #96834 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #51637 |
Applications : | ELISA Detection, Western Blot |