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CX3CL1/Fractalkine: Simple Plex

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

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3 results for "CX3CL1/Fractalkine Simple Plex" in Products

CX3CL1/Fractalkine: Simple Plex

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

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3 results for "CX3CL1/Fractalkine Simple Plex" in Products

Simple Plex Human CX3CL1/Fractalkine assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: 898143
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Control for use with Human CX3CL1/Fractalkine Simple Plex Cartridge Kit

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