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CX3CL1/Fractalkine: Proteins and Enzymes

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

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16 results for "CX3CL1/Fractalkine Proteins and Enzymes" in Products

CX3CL1/Fractalkine: Proteins and Enzymes

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

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16 results for "CX3CL1/Fractalkine Proteins and Enzymes" in Products

BA, Bind

Biotinylated

BA

N-truncated

Catalog #: NBP1-76467PEP
AC
PAGE
Catalog #: NBP1-89309PEP
AC
Catalog #: NBP2-35038
Bioactivity, PAGE
Bioactivity, PAGE
Bioactivity, PAGE
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