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52 results for "Compounds for Stem Cell Differentiation Small Molecules and Peptides" in Products

Compounds for Stem Cell Differentiation Small Molecules and Peptides

Adenylyl cyclase activator

Alternate Names:
Coleonol,Colforsin
Chemical Name:
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(2)

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Alternate Names:
LDN 193189 2HCl
Chemical Name:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity:
≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names:
Compound C,BML-275
Chemical Name:
6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity:
≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity:
≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)

AMPK activator

Chemical Name:
N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Purity:
≥99%
AMPK activator

Selective JNK inhibitor

Chemical Name:
Anthra[1-9-cd]pyrazol-6(2H)-one
Purity:
≥98%
Selective JNK inhibitor

Anti-inflammatory glucocorticoid

Chemical Name:
(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Purity:
≥98%
Anti-inflammatory glucocorticoid

γ-secretase inhibitor; induces neuronal differentiation

Alternate Names:
γ-Secretase Inhibitor XXI
Chemical Name:
N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity:
≥98%
γ-secretase inhibitor; induces neuronal differentiation

High affinity PKC activator; also APP modulator

Chemical Name:
(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
Purity:
≥98%
High affinity PKC activator; also APP modulator

Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

Alternate Names:
SIK inhibitor 1
Chemical Name:
1-(2,4-Dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea
Purity:
≥98%
Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

DAPT synthesized to Ancillary Material Grade

Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity:
≥99%
DAPT synthesized to Ancillary Material Grade

Endogenous retinoic acid receptor agonist

Alternate Names:
Tretinoin,ATRA
Chemical Name:
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity:
≥98%
iPSC differentiation with retinoic acid
(2)

Activator of LKB1/AMPK; antidiabetic agent

Chemical Name:
N,N-Dimethylimidodicarbonimidic diamide hydrochloride
Activator of LKB1/AMPK; antidiabetic agent

Selective ALK2 inhibitor

Chemical Name:
4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity:
≥98%
Selective ALK2 inhibitor

FGFR1 and -3 inhibitor

Chemical Name:
N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity:
≥98%
FGFR1 and -3 inhibitor

Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

Chemical Name:
2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
Purity:
≥95%
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

Potent AMPK activator

Chemical Name:
6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Purity:
≥98%
Potent AMPK activator

Endogenous agonist of LPA1 and LPA2

Chemical Name:
1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
Endogenous agonist of LPA1 and LPA2

Smo receptor agonist

Chemical Name:
9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Purity:
≥98%
applications of purmorphamine in neurons derived from hiPSCs
(2)

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name:
O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity:
≥98%
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

5-HT reuptake inhibitor

Chemical Name:
N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
Purity:
≥98%
5-HT reuptake inhibitor

CK1 inhibitor

Chemical Name:
N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
Purity:
≥99%
CK1 inhibitor

Histone deacetylase inhibitor

Chemical Name:
Butanoic acid sodium salt
Histone deacetylase inhibitor

Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Chemical Name:
N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
Purity:
≥98%
Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

PDE inhibitor (non-selective)

Chemical Name:
3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity:
≥98%
PDE inhibitor (non-selective)
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