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DAPT

Catalog # 2634 | Tocris Bioscience a Bio-Techne Brand
γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
Gamma γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
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Key Product Details

Description: γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99% (HPLC)
Molecular Weight: 432.46

Citations for DAPT (53)

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Customer Reviews for DAPT (6)

4.8 out of 5
6 customer ratings
5 stars
83%
4 stars
17%
3 stars
0%
2 stars
0%
1 star
0%

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  • For hPSC culture
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Human PSC
    For hPSC culture, final concentration 10 μM DAPT.
    Make 100µl aliquots and keep them at −20 °C for up to 6 months.
    DAPT Serum 2634
  • works well
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Hippocampal neuron
    gamma -secretase (100 nM BMS 299897 and 250 nM DAPT)
    DAPT Serum 2634
  • The hiPSCs were maintained with Essential 8 Flex Medium with DAPT
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: ipsc
    2.5 μM
    DAPT Serum 2634
  • DAPT succesful for dopaminergic neuron differentiation
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Used successfully for the differentiation of iPSCs into dopaminergic neurons.
    Solubilised in DMSO.
    DAPT Serum 2634
  • used in human cell line cultures
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    In cell line culture of human cells
  • Works great.
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Induced pluripotent stem cells
    I used this product for differentiation of iPSCs into dopaminergic neurons according to the protocol published in Kriks et al, 2011.I used the concentration 10uM and it works really well.

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Product Documents for DAPT

Certificate of Analysis

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