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Purmorphamine

Smoothened Receptor Agonists Small Molecule
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4551/10
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Key Product Details

Description: Smo receptor agonist
Chemical Name: 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Purity: ≥98% (HPLC)
Molecular Weight: 520.62

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  • Usage Information
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: iPSC
    iPSC-derived hypothalamic neuron differentiation activation by Smoothened agonist SAG 1 μM and purmorphamine 1 μM.
    From Day 2 to day 9 to direct the cells toward ventral diencephalon with regular media change every 2 days.
    Purmorphamine Serum 4551
  • For differentiation of DaNs
    Name: Phi Anh Phan
    Species: Human
    Cell Line/Tissue: iPSC
    Used for the differentiation of human iPSCs into dopaminergic neurons (Kriks et al.,2011).
    Purmorphamine Serum 4551
  • Great for differentiation of huiPSCs into DaNs!
    Name: Phi Anh Phan
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: iPSC
    Purmorphamine was used to differentiate human iPSCs into dopaminergic neurons with above 60% TH positive cells.
    Purmorphamine Serum 4551

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Certificate of Analysis

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