The product literature for recombinant human EGF indicates to reconstitute at 500 μg/mL. Can I reconstitute to a lower concentration?

Name: Recombinant Human EGF Protein, CF
Brand: R&D Systems
SKU: 236-EG
Rating: 5 (28 reviews)

For recombinant human EGF, stability and activity testing has been performed after reconstitution to 500 μg/mL. We cannot guarantee performance of the protein after reconstitution to a lower concentration. We would recommend reconstituting and storing at 500 μg/mL in single-use aliquots, diluting to the working concentration just prior to use.

Recombinant Human EGF Protein, CF

R&D Systems, Inc. a Bio-Techne Brand

Catalog # 236-EG

Citations (689)

(28)

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	P01133
Applications:	Bioactivity

View Full Technical Details for Recombinant Human EGF Protein, CF

Product Specifications for Recombinant Human EGF Protein, CF

Source	E. coli-derived human EGF protein Asn971-Arg1023, with an N-terminal Met
Purity	>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Met
Predicted Molecular Mass	6 kDa
SDS-PAGE	6 kDa, reducing conditions
Activity	Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al. (1991) Proc. Natl. Acad. Sci. USA 88:415. The ED₅₀ for this effect is 20-100 pg/mL.

Scientific Data Examples for Recombinant Human EGF Protein, CF

	Recombinant Human EGF Protein Bioactivity Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED₅₀ for this effect is 20‑100 pg/mL.
	Recombinant Human EGF Protein SDS-PAGE 1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa.
	iPSC-derived Human Intestinal Organoids Cultured using Recombinant Human EGF Protein. iPSC-derived human intestinal organoids were cultured using Cultrex™ UltiMatrix RGF Basement Membrane Extract (BME001-05) and intestinal organoid culture medium, which includes Recombinant Human EGF (Catalog # 236-EG), Recombinant Human Noggin (6057-NG), Recombinant Human R-Spondin 1 (4645-RS), and Recombinant Human Wnt-3a (5036-WN), along with the other reagents listed in the intestinal organoid culture medium recipe in the human intestinal organoid culture protocol. (A) Human intestinal organoids were stained using a Rat Anti-Human/Mouse/Rat Vimentin Monoclonal Antibody (MAB2105; green) and a Goat Anti-Human/Mouse Desmin Antigen Affinity-purified Polyclonal Antibody (AF3844; red) to visualize myofibroblast cells and counterstained with DAPI (5748; blue). (B) Human intestinal organoids were stained using a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF748; green) and a Mouse Anti-Human MUC2 Monoclonal Antibody (Novus Biologicals, Catalog # NBP2-44431; red) and counterstained with DAPI (5748; blue).
	Adult Stem Cell-derived Human Descending Colon Organoids Cultured using Recombinant Human EGF Protein. Adult stem cells isolated from human descending colon were embedded in Cultrex UltiMatrix RGF Basement Membrane Extract (BME001-05) and cultured for 30 days in intestinal organoid culture medium, which includes Recombinant Human EGF (Catalog # 236-EG), Recombinant Human Noggin (6057-NG), Recombinant Human R-Spondin 1 (4645-RS), and Recombinant Human Wnt-3a (5036-WN), along with the other reagents listed in the intestinal organoid culture medium recipe in the human intestinal organoid culture protocol. (A) Organoids were fixed and stained with a Mouse Anti-Human MUC2 Monoclonal Antibody (Novus Biologicals; Catalog # NBP2-44431; green) to visualize intestinal goblet cells and counterstained with a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF748; red) and DAPI (5748; blue). The image shown was taken at 10x magnification. (B) Organoids were fixed and stained with a Mouse Anti-Human Chromogranin A Monoclonal Antibody (MAB90981; green) to visualize enteroendocrine cells and counterstained with a Goat Anti-Human/Mouse E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF748; red) and DAPI (5748; blue). The image shown was taken at 20x magnification.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

236-EG

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute at 500 μg/mL in sterile PBS.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

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Background: EGF

Epidermal growth factor (EGF) is a small, potent growth factor capable of inducing cell proliferation, differentiation, and survival. EGF is the founding member of the EGF family that also includes TGF-alpha, amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), heparin‑binding EGF‑like growth factor (HB‑EGF), epigen, and the neuregulins (NRG)-1 through -6 (1). Members of The EGF family are characterized by a shared structural motif, the EGF‑like domain, which contains three intramolecular disulfide bonds that are formed by six similarly spaced, conserved cysteine residues (2). These disulfide bonds are essential for proper protein conformation and receptor binding. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated proteolysis (1). The full length EGF protein is 1207 amino acids (aa) (EGF precursor) containing nine EGF domains and nine LDLR class B repeats. However, the mature protein is much smaller, only 53 aa, and is generated by proteolytic cleavage of the EGF domain proximal to the transmembrane region (3). EGF is well conserved across mammals with mature human EGF 70% identical to mature mouse and rat EGF. Physiologically, EGF is found in various body fluids, including blood, milk, urine, saliva, seminal fluid, pancreatic juice, cerebrospinal fluid, and amniotic fluid (4). EGF is a high affinity ligand of the EGF receptor (ErbB). Four ErbB (HER) family receptor tyrosine kinases including EGFR/ErbB1, ErbB2, ErbB3 and ErbB4, mediate responses to EGF family members (5). EGF binding induces dimerization of the EGF receptor resulting in activation of the protein tyrosine kinase signaling pathway. These receptors undergo a complex pattern of ligand-induced homo- or hetero-dimerization to transduce EGF family signals (6, 7). EGF binds ErbB1 and depending on the context, induces the formation of homodimers or heterodimers containing ErbB2. Dimerization results in autophosphorylation of the receptor at specific tyrosine residues to create docking sites for a variety of signaling molecules (5, 8). Biological activities ascribed to EGF include epithelial development, angiogenesis, inhibition of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture.

Item	Value
References	Harris, R.C. et al. (2003) Exp. Cell Res. 284:2. Carpenter, G. and Cohen, S. (1990) J. Biol. Chem. 265:7709. Bell, G.I. et al. (1986) Nucl. Acids Res. 14:8427. Carpenter, G. and Zendegui, J.G. (1986) Exp. Cell Res. 164:1. Jorissen, R.N. et al. (2003) Exp. Cell Res. 284:31. Gamett, D.C. et al. (1997) J. Biol. Chem. 272:12052. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. 91:1500. Qian, X. et al. (1999) J. Biol. Chem. 274:574.
Long Name	Epidermal Growth Factor
Entrez Gene IDs	1950 (Human); 13645 (Mouse); 25313 (Rat)
Alternate Names	EGF, HOMG4, URG, Urogastrone, beta-urogastrone, epidermal growth factor, epidermal growth factor (beta-urogastrone), hEGF, pro-epidermal growth factor

Citations for Recombinant Human EGF Protein, CF (689)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human EGF Protein, CF include:

Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Sighel et al. (2023-01-01), Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth European Journal of Medicinal Chemistry, 246(0):114979.
PMID: 36495628
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

T Fujimori et al. (2023-01-01), Effects of a monoclonal antibody against (pro)renin receptor on gliomagenesis Scientific Reports, 13(1):808.
PMID: 36646875
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MF Wells et al. (2023-01-01), Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages Cell Stem Cell, 0(0).
PMID: 36796362
Species: Human
Sample Types: Organoid
Applications: Bioassay

EF Cohn et al. (2023-01-01), Pervasive environmental chemicals impair oligodendrocyte development bioRxiv : the preprint server for biology, 0(0).
PMID: 36798415
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

M Shono et al. (2023-01-01), Induction of primordial germ cell-like cells from common marmoset embryonic stem cells by inhibition of WNT and retinoic acid signaling Scientific Reports, 13(1):3186.
PMID: 36823310
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RC Gimple et al. (2023-01-01), Sorting-nexin-10 sustains platelet-derived growth factor receptor signaling in glioblastoma stem cells via endosomal protein sorting JCI Insight, 0(0).
PMID: 36795488
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

TT Lemmetyine et al. (2023-01-01), Fibroblast-derived EGF ligand Neuregulin-1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth Disease Models Mechanisms, 2023;0(0).
PMID: 36912192
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Suenaga et al. (2022-01-01), Microwell bag culture for large-scale production of homogeneous islet-like clusters Scientific Reports, 12(1):5221.
PMID: 35338209
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

V De Re et al. (2022-01-01), HER2-CDH1 Interaction via Wnt/B-Catenin Is Associated with Patients' Survival in HER2-Positive Metastatic Gastric Adenocarcinoma Cancers, 14(5).
PMID: 35267574
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Uehara et al. (2022-01-01), Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids Stem Cell Reports, 0(0).
PMID: 35245440
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Miura et al. (2022-01-01), Engineering brain assembloids to interrogate human neural circuits Nature Protocols, 17(1):15-35.
PMID: 34992269
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

D Liu et al. (2022-01-01), Conversion of Human Fibroblasts into Induced Neural Stem Cells by Small Molecules International Journal of Molecular Sciences, 23(3).
PMID: 35163660
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SH Gao et al. (2022-01-01), Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer Cell Calcium, 102(0):102527.
PMID: 35026540
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Yu et al. (2022-01-01), Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression Cancers, 14(2).
PMID: 35053442
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Hunziker et al. (2022-01-01), Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation Cell Reports, 38(4):110306.
PMID: 35081340
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Pan et al. (2022-01-01), EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3 Molecular Cancer, 21(1):16.
PMID: 35031058
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EQX Mulcahy et al. (2022-01-01), MicroRNA 3928 Suppresses Glioblastoma through Downregulation of Several Oncogenes and Upregulation of p53 International Journal of Molecular Sciences, 23(7).
PMID: 35409289
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SY Zhao et al. (2022-01-01), CERS6-AS1 contributes to the malignant phenotypes of colorectal cancer cells by interacting with miR-15b-5p to regulate SPTBN2 The Kaohsiung journal of medical sciences, 0(0).
PMID: 35146902
Species: Human
Sample Types: Organoids
Applications: Bioassay

MM Capeling et al. (2022-01-01), Suspension culture promotes serosal mesothelial development in human intestinal organoids Cell Reports, 38(7):110379.
PMID: 35172130
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Hu et al. (2022-01-01), Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias Nature, 602(7897):518-522.
PMID: 35140400
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Han et al. (2022-01-01), Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis Cell Reports, 39(1):110595.
PMID: 35385726
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DA Eagles et al. (2022-01-01), A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals Proceedings of the National Academy of Sciences of the United States of America, 119(7).
PMID: 35131940
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Pang et al. (2022-01-01), Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells Cell Death Disease, 2022;13(2):169.
PMID: 35194034
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Fu et al. (2022-01-01), Cooperative regulation of adherens junction expansion through Epidermal Growth Factor Receptor (EGFR) activation Journal of Cell Science, 0(0).
PMID: 35099018
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Kim et al. (2022-01-01), Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids Nature Communications, 13(1):1692.
PMID: 35354790
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Bernareggi et al. (2022-01-01), CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Nature Communications, 13(1):1899.
PMID: 35393416
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Wang et al. (2022-01-01), EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association The Journal of Biological Chemistry, 0(0):102340.
PMID: 35931120
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

K Wang et al. (2022-01-01), Cardioprotection of Klotho against myocardial infarction-induced heart failure through inducing autophagy Mechanisms of Ageing and Development, 207(0):111714.
PMID: 35931242
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

EJ Sohn (2022-01-01), Differentially expression and function of circular RNAs in ovarian cancer stem cells Journal of ovarian research, 15(1):97.
PMID: 35978436
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Ratliff et al. (2022-01-01), Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma International Journal of Molecular Sciences, 23(12).
PMID: 35743016
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Semkova et al. (2022-01-01), Dynamics of Metabolic Pathways and Stress Response Patterns during Human Neural Stem Cell Proliferation and Differentiation Cells, 11(9).
PMID: 35563695
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AK Nair et al. (2022-01-01), Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians Cells, 11(9).
PMID: 35563754
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

I Jun et al. (2022-01-01), Activation of ADRB2/PKA Signaling Pathway Facilitates Lipid Synthesis in Meibocytes, and Beta-Blocker Glaucoma Drug Impedes PKA-Induced Lipid Synthesis by Inhibiting ADRB2 International Journal of Molecular Sciences, 23(16).
PMID: 36012741
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

K Li et al. (2022-01-01), Counterintuitive production of tumor-suppressive secretomes from Oct4- and c-Myc-overexpressing tumor cells and MSCs Theranostics, 12(7):3084-3103.
PMID: 35547745
Species: Human
Sample Types: Organoid
Applications: Bioassay

EJ Sohn (2022-01-01), PIK3R3, a regulatory subunit of PI3K, modulates ovarian cancer stem cells and ovarian cancer development and progression by integrative analysis BMC Cancer, 22(1):708.
PMID: 35761259
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MC Beer et al. (2022-01-01), Kir4.2 Potassium Channels in Retinal Pigment Epithelial Cells In Vitro: Contribution to Cell Viability and Proliferation, and Down-Regulation by Vascular Endothelial Growth Factor Biomolecules, 12(6).
PMID: 35740973
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Sun et al. (2022-01-01), TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC Cell Death Disease, 2022;13(5):450.
PMID: 35546143
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

S Fan et al. (2022-01-01), Epithelial JAM-A is fundamental for intestinal wound repair in-vivo JCI Insight, 0(0).
PMID: 35943805
Species: Equine
Sample Types: Organoid
Applications: Bioassay

RE Thompson et al. (2022-01-01), Equine Oviductal Organoid Generation and Cryopreservation Methods and protocols, 5(3).
PMID: 35736552
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

D Hao et al. (2022-01-01), Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair Theranostics, 12(13):6021-6037.
PMID: 35966577
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Wang et al. (2022-01-01), Molecularly cleavable bioinks facilitate high-performance digital light processing-based bioprinting of functional volumetric soft tissues Nature Communications, 13(1):3317.
PMID: 35680907
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Vicioso-Ma et al. (2022-01-01), JMJD3 intrinsically disordered region links the 3D-genome structure to TGFbeta-dependent transcription activation Nature Communications, 13(1):3263.
PMID: 35672304
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Chen et al. (2022-01-01), IQGAP1 is positively correlated with PD-L1 and regulates its expression via mediating STAT proteins phosphorylation Oncogene, 108(0):108897.
PMID: 35729832
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

U Mala et al. (2022-01-01), Integrative analysis of cell adhesion molecules in glioblastoma identified prostaglandin F2 receptor inhibitor (PTGFRN) as an essential gene BMC Cancer, 22(1):642.
PMID: 35690717
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CG Park et al. (2022-01-01), Cytoplasmic LMO2-LDB1 Complex Activates STAT3 Signaling through Interaction with gp130-JAK in Glioma Stem Cells Cells, 11(13).
PMID: 35805116
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Cecchi et al. (2022-01-01), Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase Frontiers in Pharmacology, 13(0):911019.
PMID: 35847038
Species: Human
Sample Types: Organoid
Applications: Bioassay

H Marei et al. (2022-01-01), Antibody targeting of E3 ubiquitin ligases for receptor degradation Nature, 610(7930):182-189.
PMID: 36131013
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Tabata et al. (2022-01-01), Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas Vaccines, 10(7).
PMID: 35891239
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

GM Jowett et al. (2022-01-01), Organoids capture tissue-specific innate lymphoid cell development in mice and humans Cell Reports, 40(9):111281.
PMID: 36044863
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Jeising et al. (2022-01-01), In-Vitro Use of Verteporfin for Photodynamic Therapy in Glioblastoma Photodiagnosis and photodynamic therapy, 0(0):103049.
PMID: 35932958
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

DS Lee et al. (2022-01-01), Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells Stem Cells International, 2022(0):1092184.
PMID: 36213683
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JI Takahashi et al. (2022-01-01), Synchronous intracellular delivery of EGFR-targeted antibody-drug conjugates by p38-mediated non-canonical endocytosis Scientific Reports, 12(1):11561.
PMID: 35798841
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CC Dibble et al. (2022-01-01), PI3K drives the de novo synthesis of coenzyme A from vitamin B5 Nature, 608(7921):192-198.
PMID: 35896750
Species: Human
Sample Types: Spheroids
Applications: Bioassay

HY Chen et al. (2022-01-01), Long noncoding RNA Smyca coactivates TGF-beta/Smad and Myc pathways to drive tumor progression Journal of hematology oncology, 2022;15(1):85.
PMID: 35794621
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

PC Kinnunen et al. (2022-01-01), Computational modeling implicates protein scaffolding in p38 regulation of Akt Journal of theoretical biology, 555(0):111294.
PMID: 36195198
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Li et al. (2022-01-01), beta2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages Oncogene, 0(0).
PMID: 35841593
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Guo et al. (2022-01-01), CDK4/6 inhibition enhances oncolytic virus efficacy by potentiating tumor-selective cell killing and T cell activation in refractory glioblastoma Cancer Research, 0(0).
PMID: 35792620
Species: Human
Sample Types: Organoids
Applications: Bioassay

R Moser et al. (2022-01-01), Pharmacological targeting of TFIIH suppresses KRAS mutant pancreatic ductal adenocarcinoma and synergizes with TRAIL Cancer Research, 0(0).
PMID: 35819261
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W He et al. (2022-01-01), Long-term maintenance of human endometrial epithelial stem cells and their therapeutic effects on intrauterine adhesion Cell bioscience, 2022;12(1):175.
PMID: 36258228
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

D Sardar et al. (2022-01-01), Sox9 directs divergent epigenomic states in brain tumor subtypes Oncogene, 119(29):e2202015119.
PMID: 35858326
Species: Human
Sample Types: Spheroid
Applications: Bioassay

O Revah et al. (2022-01-01), Maturation and circuit integration of transplanted human cortical organoids Nature, 610(7931):319-326.
PMID: 36224417
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Tu et al. (2022-01-01), Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K inï¿½triple-negative breast cancer Proceedings of the National Academy of Sciences of the United States of America, 119(43):e2203180119.
PMID: 36269860
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JE Kaserman et al. (2022-01-01), Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity Cell Reports, 41(10):111775.
PMID: 36476855
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Hattori et al. (2022-01-01), Combination of Ad-SGE-REIC and bevacizumab modulates glioma progression by suppressing tumor invasion and angiogenesis PLoS ONE, 17(8):e0273242.
PMID: 36006934
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Lungova et al. (2022-01-01), Exposure to e-cigarette vapor extract induces vocal fold epithelial injury and triggers intense mucosal remodeling Oncogene, 0(0).
PMID: 35770504
Species: Human
Sample Types: Organoid
Applications: Bioassay

AN Cho et al. (2022-01-01), Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus Cells, 11(20).
PMID: 36291062
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Degorre et al. (2022-01-01), Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb Cancer Cell International, 22(1):389.
PMID: 36482431
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HJ Kim et al. (2022-01-01), 7beta-22 Dihydroxyhopane, Isolated from the Sub-Antarctic Lichen, Inhibits the Viability and Stemness in Glioma Stem Like Cells OncoTargets and Therapy, 15(0):1375-1383.
PMID: 36411942
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

TM Triolo et al. (2022-01-01), Stem-Cell-Derived beta-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity Cells, 11(23).
PMID: 36497105
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Le-Bel et al. (2022-01-01), Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells Cells, 11(17).
PMID: 36078126
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Liu et al. (2022-01-01), Glucocorticoid-induced microRNA-378 signaling mediates the progression of pancreatic cancer by enhancing autophagy Cell Death Disease, 2022;13(12):1052.
PMID: 36535942
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Wang et al. (2022-01-01), Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes Cell Stem Cell, 29(10):1491-1504.e9.
PMID: 36206732
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Beucher et al. (2022-01-01), The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A Nature Cell Biology, 0(0).
PMID: 36202974
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HC Wang et al. (2022-01-01), Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling Journal of Biomedical Science, 29(1):99.
PMID: 36411463
R Qureshi et al. (2022-01-01), Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis Cell Reports, 41(7):111672.
PMID: 36384125
Species: Transgenic Mouse
Sample Types: Cells
Applications: Bioassay

M Ishibane et al. (2022-01-01), Effects of a novel hepatitis B anti-viral drug E-CFCP in renal organic acid transporters Journal of pharmacological sciences, 150(4):201-203.
PMID: 36344041
Species: Feline
Sample Types: Organoids
Applications: Bioassay

RE Thompson et al. (2022-01-01), Generation and cryopreservation of feline oviductal organoids Theriogenology, 196(0):167-173.
PMID: 36423511
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Otsu et al. (2022-01-01), Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells Journal of pharmacological sciences, 150(4):279-288.
PMID: 36344051
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EJ Kim et al. (2022-01-01), The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2 Cell Reports, 41(8):111626.
PMID: 36417870
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Li et al. (2022-01-01), The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate Cell bioscience, 2022;12(1):181.
PMID: 36333732
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Madden-Hen et al. (2022-01-01), Loss of mismatch repair promotes a direct selective advantage in human stem cells Stem Cell Reports, 0(0).
PMID: 36368329
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Cuevas et al. (2022-01-01), Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model Toxicology reports, 9(0):806-813.
PMID: 36518412
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Roebroek et al. (2021-01-01), Simultaneous readout of multiple FRET pairs using photochromism Nature Communications, 12(1):2005.
PMID: 33790271
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

WZ Peng et al. (2021-01-01), hnRNPA2B1 regulates the alternative splicing of BIRC5 to promote gastric cancer progression Cancer Cell International, 21(1):281.
PMID: 34044823
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JA Sninsky et al. (2021-01-01), Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Oncotarget, 12(4):278-291.
PMID: 33659040
Species: Human
Sample Types: Organoid
Applications: Bioassay

RM Agoglia et al. (2021-01-01), Primate cell fusion disentangles gene regulatory divergence in neurodevelopment Nature, 0(0).
PMID: 33731928
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Preisler et al. (2021-01-01), Heterozygous APC germline mutations impart predisposition to colorectal cancer Scientific Reports, 11(1):5113.
PMID: 33664379
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Hao et al. (2021-01-01), Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression Respiratory Research, 22(1):58.
PMID: 33596919
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KA Lidberg et al. (2021-01-01), Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease Scientific Reports, 11(1):4722.
PMID: 33633318
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Mishra et al. (2021-01-01), Sex-Specific Isolation and Propagation of Human Premeiotic Fetal Germ Cells and Germ Cell-Like Cells Cells, 10(5).
PMID: 34065661
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Mischler et al. (2021-01-01), Two distinct trophectoderm lineage stem cells from human pluripotent stem cells The Journal of Biological Chemistry, 0(0):100386.
PMID: 33556374
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Yuan et al. (2021-01-01), The histone demethylase KDM2B regulates human primordial germ cell-like cells specification International journal of biological sciences, 17(2):527-538.
PMID: 33613110
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MDA Norman et al. (2021-01-01), Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy Nature Protocols, 0(0).
PMID: 33854255
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Sighel et al. (2021-01-01), Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth Cell Reports, 35(4):109024.
PMID: 33910005
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

S van der Po et al. (2021-01-01), NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation Cell Reports, 35(1):108949.
PMID: 33826887
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Kaneko et al. (2021-01-01), Effects of islatravir (4'-ethynyl-2-fluoro-2'-deoxyadenosine or EFdA) on renal tubular cells and islatravir's interactions with organic anion transporters Journal of pharmacological sciences, 146(2):82-87.
PMID: 33941324
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Io et al. (2021-01-01), Capturing human trophoblast development with naive pluripotent stem cells inï¿½vitro Cell Stem Cell, 28(6):1023-1039.e13.
PMID: 33831365
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Phoomak et al. (2021-01-01), The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress Science Advances, 7(3).
PMID: 33523898
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

O Kwon et al. (2021-01-01), The development of a functional human small intestinal epithelium model for drug absorption Science Advances, 7(23).
PMID: 34078609
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Dong et al. (2021-01-01), Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma Nature Communications, 12(1):3974.
PMID: 34172737
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Wang et al. (2021-01-01), Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting JCI Insight, 6(12).
PMID: 34156031
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Jamal Jame et al. (2021-01-01), Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD International Journal of Molecular Sciences, 22(13).
PMID: 34281240
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Barra et al. (2021-01-01), D-Propranolol Impairs EGFR Trafficking and Destabilizes Mutant p53 Counteracting AKT Signaling and Tumor Malignancy Cancers, 13(14).
PMID: 34298835
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Andersson et al. (2021-01-01), Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale Cancers, 13(11).
PMID: 34198773
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MO Lee et al. (2021-01-01), Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells Nature Communications, 12(1):4492.
PMID: 34301945
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IT Stancil et al. (2021-01-01), Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional Nature Communications, 12(1):4566.
PMID: 34315881
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Morales et al. (2021-01-01), CRMP2 as a Candidate Target to Interfere with Lung Cancer Cell Migration Biomolecules, 11(10).
PMID: 34680167
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Miyake et al. (2021-01-01), alpha-glucosyl-rutin activates immediate early genes in human induced pluripotent stem cells Stem Cell Research, 56(0):102511.
PMID: 34455240
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AV Parent et al. (2021-01-01), Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection Cell Reports, 36(7):109538.
PMID: 34407395
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DG Kim et al. (2021-01-01), Gintonin influences the morphology and motility of adult brain neurons via LPA receptors Journal of Ginseng Research, 45(3):401-407.
PMID: 34025133
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Bahl et al. (2021-01-01), EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function Cell Death Disease, 2021;12(5):469.
PMID: 33976119
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Tarallo et al. (2021-01-01), Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease Embo Molecular Medicine, 0(0):e14434.
PMID: 34606154
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Q Zhu et al. (2021-01-01), Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage Cell Reports, 34(6):108735.
PMID: 33567277
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Jung et al. (2021-01-01), Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma Nature Communications, 12(1):1014.
PMID: 33579922
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Wang et al. (2021-01-01), CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance Cell Stem Cell, 0(0).
PMID: 33945793
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

M Chiara Per et al. (2021-01-01), Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured inï¿½vitro Theriogenology, 168(0):1-12.
PMID: 33826978
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Aghazadeh et al. (2021-01-01), Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models Cell Stem Cell, 0(0).
PMID: 34480863
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

G Belthier et al. (2021-01-01), CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM Cancers, 13(19).
PMID: 34638450
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A De Zutter et al. (2021-01-01), The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors Cancers, 13(20).
PMID: 34680238
Species: Rabbit
Sample Types: Whole Cells
Applications: Bioassay

T Kobayashi et al. (2021-01-01), Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells Cell Reports, 37(2):109812.
PMID: 34644585
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Gebregiwor et al. (2021-01-01), The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors Nature Communications, 12(1):6274.
PMID: 34725361
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Kim et al. (2021-01-01), CXCR4 Regulates Temporal Differentiation via PRC1 Complex in Organogenesis of Epithelial Glands International Journal of Molecular Sciences, 22(2).
PMID: 33435128
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Ghatak et al. (2021-01-01), FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells International Journal of Molecular Sciences, 22(2).
PMID: 33451103
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Tanaka et al. (2021-01-01), Glioma cells require one-carbon metabolism to survive glutamine starvation Acta neuropathologica communications, 9(1):16.
PMID: 33468252
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

M Niu et al. (2021-01-01), FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth Nature Communications, 12(1):5919.
PMID: 34635651
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

T Arad et al. (2021-01-01), CD200 -dependent and -independent immune-modulatory functions of neural stem cells Stem Cell Research, 56(0):102559.
PMID: 34634761
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Dolde et al. (2021-01-01), Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis Assays International Journal of Molecular Sciences, 22(18).
PMID: 34576243
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Feng et al. (2021-01-01), Abnormally elevated ubiquilin?1 expression in breast cancer regulates metastasis and stemness via AKT signaling Oncology reports, 46(5).
PMID: 34528694
Species: Human
Sample Types: Spheroid
Applications: Bioassay

L Jerby-Arno et al. (2021-01-01), Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma Nature Medicine, 0(0).
PMID: 33495604
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Jalali Mot et al. (2021-01-01), D-Mannose Slows Glioma Growth by Modulating Myeloperoxidase Activity Cancers, 13(24).
PMID: 34944979
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Dokladny et al. (2021-01-01), Cross-Talk between Probiotic Nissle 1917 and Human Colonic Epithelium Affects the Metabolite Composition and Demonstrates Host Antibacterial Effect Metabolites, 11(12).
PMID: 34940599
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AK Eicher et al. (2021-01-01), Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells Cell Stem Cell, 0(0).
PMID: 34856121
Species: Human
Sample Types: Spheroid
Applications: Bioassay

S Siddharth et al. (2021-01-01), Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression Elife, 10(0).
PMID: 34889737
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RJ Geusz et al. (2021-01-01), Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Nature Communications, 12(1):6636.
PMID: 34789735
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Gu et al. (2021-01-01), ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation Nature Communications, 12(1):6711.
PMID: 34795238
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PE Farahani et al. (2021-01-01), Substratum stiffness regulates Erk signaling dynamics through receptor-level control Cell Reports, 37(13):110181.
PMID: 34965432
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KX Li et al. (2021-01-01), Conversion of Osteoclasts into Bone-Protective, Tumor-Suppressing Cells Cancers, 13(22).
PMID: 34830748
Species: Human
Sample Types: Organoid
Applications: Bioassay

V Chesnokova et al. (2021-01-01), Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage Cell Reports, 37(11):110068.
PMID: 34910915
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AF de Souza et al. (2021-01-01), Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients Cells, 10(11).
PMID: 34831322
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Wu et al. (2021-01-01), A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity Genome Biology, 22(1):33.
PMID: 33446260
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Lita et al. (2021-01-01), IDH1 mutations induce organelle defects via dysregulated phospholipids Nature Communications, 12(1):614.
PMID: 33504762
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RR Madsen et al. (2021-01-01), Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype PloS Genetics, 17(11):e1009876.
PMID: 34762647
Species: Human
Sample Types: Organoid
Applications: Bioassay

SK Sarvestani et al. (2021-01-01), Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity Nature Communications, 12(1):262.
PMID: 33431859
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Nomi et al. (2021-01-01), Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs Cell Reports, 34(5):108715.
PMID: 33535050
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Gordon et al. (2021-01-01), Long-term maturation of human cortical organoids matches key early postnatal transitions Nature Neuroscience, 0(0).
PMID: 33619405
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Tu et al. (2021-01-01), TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation Autophagy, 0(0).
PMID: 33618632
Species: Human
Sample Types: Organoid
Applications: Bioassay

BM Larsen et al. (2021-01-01), A pan-cancer organoid platform for precision medicine Cell Reports, 36(4):109429.
PMID: 34320344
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Ulman et al. (2021-01-01), Myogenic Differentiation of iPS Cells Shows Different Efficiency in Simultaneous Comparison of Protocols Cells, 10(7).
PMID: 34359837
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Yoshimatsu et al. (2021-01-01), In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells Stem Cell Research, 52(0):102233.
PMID: 33607469
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Lee et al. (2021-01-01), Repositioning Trimebutine Maleate as a Cancer Treatment Targeting Ovarian Cancer Stem Cells Cells, 10(4).
PMID: 33923707
Species: Human
Sample Types: Organoid
Applications: Bioassay

SM Dieter et al. (2021-01-01), Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer Cell Reports, 36(3):109394.
PMID: 34289372
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Abdullah et al. (2021-01-01), Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific Reports, 11(1):8585.
PMID: 33883596
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Ryding et al. (2021-01-01), Neurodegeneration Induced by Anti-IgLON5 Antibodies Studied in Induced Pluripotent Stem Cell-Derived Human Neurons Cells, 10(4).
PMID: 33917676
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Deng et al. (2021-01-01), Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusion PloS Neglected Tropical Diseases, 15(7):e0009508.
PMID: 34237073
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Lin et al. (2021-01-01), In Vitro Study of Human Immune Responses to Hyaluronic Acid Hydrogels, Recombinant Spidroins and Human Neural Progenitor Cells of Relevance to Spinal Cord Injury Repair Cells, 10(7).
PMID: 34359882
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

K Kawai et al. (2020-01-01), Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies Mol Ther Methods Clin Dev, 17(0):49-57.
PMID: 31890740
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

M Lundberg et al. (2020-01-01), Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy Biosci. Rep., 0(0).
PMID: 31919522
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Ramos et al. (2020-01-01), SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner Int J Mol Sci, 21(2).
PMID: 31963392
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Cai et al. (2020-01-01), Glioblastoma Exhibits Inter-Individual Heterogeneity of TSPO and LAT1 Expression in Neoplastic and Parenchymal Cells Int J Mol Sci, 21(2).
PMID: 31963507
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

AR Nickolls et al. (2020-01-01), Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells Cell Rep, 30(3):932-946.e7.
PMID: 31968264
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

S Yomtoubian et al. (2020-01-01), Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer Cell Rep, 30(3):755-770.e6.
PMID: 31968251
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

É Dóka et al. (2020-01-01), Control of protein function through oxidation and reduction of persulfidated states Sci Adv, 6(1):eaax8358.
PMID: 31911946
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

J Pan et al. (2020-01-01), Epithelial-mesenchymal transition suppresses ERas to activate autophagy in retinal pigment epithelial cells in proliferative vitreoretinopathy Eur Rev Med Pharmacol Sci, 24(9):4627-4634.
PMID: 32432726
Species: Human
Sample Types: cell culture

K Takeishi et al. (2020-01-01), Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells Cell Rep, 31(9):107711.
PMID: 32492423
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Verheyen et al. (2020-01-01), Spatialï¿½organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers Nucleic Acids Res., 0(0).
PMID: 32352518
Species: Human
Sample Types: Organoid
Applications: Cell Culture

S Pradhan et al. (2020-01-01), Tissue Responses to Shiga Toxin in Human Intestinal Organoids Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 32145469
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Yoshida et al. (2020-01-01), Generation of intestinal organoids derived from human pluripotent stem cells for drug testing Sci Rep, 10(1):5989.
PMID: 32249832
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

V Licursi et al. (2020-01-01), X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics Sci Rep, 10(1):6562.
PMID: 32300147
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Nair et al. (2020-01-01), Enhancing Antitumor Efficacy of Heavily Vascularized Tumors by RAMBO Virus through Decreased Tumor Endothelial Cell Activation Cancers (Basel), 12(4).
PMID: 32340193
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NK Vinckier et al. (2020-01-01), LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development Nat Commun, 11(1):2082.
PMID: 32350257
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Yamashiro et al. (2020-01-01), Generation of human oogonia from induced pluripotent stem cells in culture Nat Protoc, 15(4):1560-1583.
PMID: 32231324
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Chen et al. (2020-01-01), Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition Integr Cancer Ther, 19(0):1534735419900.
PMID: 32129091
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EB Cohen et al. (2020-01-01), Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia PLoS ONE, 15(7):e0232072.
PMID: 32645038
Species: Zebrafish
Sample Types: Whole Cells
Applications: Cell Culture

E Gronseth et al. (2020-01-01), Astrocytes influence medulloblastoma phenotypes and CD133 surface expression PLoS ONE, 15(7):e0235852.
PMID: 32628717
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Dokduang et al. (2020-01-01), In vitro and in vivo Anti-Tumor Effects of Pan-HER Inhibitor Varlitinib on Cholangiocarcinoma Cell Lines Drug Des Devel Ther, 14(0):2319-2334.
PMID: 32606601
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Sun et al. (2020-01-01), DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes Stem Cell Res, 47(0):101900.
PMID: 32622343
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

L Liu et al. (2020-01-01), Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli Sci Rep, 10(1):10533.
PMID: 32601325
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PL Hsieh et al. (2020-01-01), Soy Isoflavone Genistein Impedes Cancer Stemness and Mesenchymal Transition in Head and Neck Cancer through Activating miR-34a/RTCB Axis Nutrients, 12(7).
PMID: 32610494
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

P Ahangar et al. (2020-01-01), Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice Stem Cell Res Ther, 11(1):299.
PMID: 32680566
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

TF Dinger et al. (2020-01-01), Microenvironmentally-driven Plasticity of CD44 isoform expression determines Engraftment and Stem-like Phenotype in CRC cell lines Theranostics, 10(17):7599-7621.
PMID: 32685007
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Sieben et al. (2020-01-01), Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation PLoS Pathog., 16(7):e1008656.
PMID: 32639985
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S Findakly et al. (2020-01-01), Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals Acta Neuropathol Commun, 8(1):114.
PMID: 32690089
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SI Mae et al. (2020-01-01), Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential Cell Rep, 32(4):107963.
PMID: 32726627
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

R Malik et al. (2020-01-01), Quantitative Efficacy and Fate of Mesenchymal Stromal Cells Targeted to Cardiac Sites by Radiofrequency Catheter Ablation Cell Transplant, 29(0):9636897209142.
PMID: 32207339
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SL Boddy et al. (2020-01-01), Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs Stem Cells Int, 2020(0):3692937.
PMID: 32190057
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Xie et al. (2020-01-01), WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating &beta-Catenin/MMP9-Mediated Signaling Front Pharmacol, 11(0):98.
PMID: 32174831
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Lee et al. (2020-01-01), Calcium Channels as Novel Therapeutic Targets for Ovarian Cancer Stem Cells Int J Mol Sci, 21(7).
PMID: 32230901
Species: Human
Sample Types: Cells
Applications: Cell Culture

NJ Hogrebe et al. (2020-01-01), Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells Nat. Biotechnol., 0(0).
PMID: 32094658
Species: Human
Sample Types: Cells
Applications: Cell Culture

Y Wang et al. (2020-01-01), HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells Nat. Immunol., 21(3):274-286.
PMID: 32066947
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Pedersen et al. (2020-01-01), Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells Int J Mol Sci, 21(5).
PMID: 32111042
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

F Fang et al. (2020-01-01), Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells Stem Cell Res Ther, 11(1):100.
PMID: 32127035
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SK Ryan et al. (2020-01-01), Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection Stem Cell Reports, 0(0).
PMID: 32220329
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Ding et al. (2020-01-01), EGF released from human placental mesenchymal stem cells improves premature ovarian insufficiency via NRF2/HO-1 activation Aging (Albany NY), 12(3):2992-3009.
PMID: 32040445
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

R Bergès et al. (2020-01-01), EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis Oncotarget, 11(8):759-774.
PMID: 32165998
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

DJH Shih et al. (2020-01-01), Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma Nat. Genet., 0(0).
PMID: 32203465
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

ML Debreczeni et al. (2020-01-01), Human primary endothelial label-free biochip assay reveals unpredicted functions of plasma serine proteases Sci Rep, 10(1):3303.
PMID: 32094469
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A Schulte et al. (2020-01-01), Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo Int J Mol Sci, 21(4).
PMID: 32102484
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

R Lucero et al. (2020-01-01), Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells Cell Rep, 30(7):2065-2074.e4.
PMID: 32075753
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Y Yuan et al. (2020-01-01), In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids Cell Res., 0(0).
PMID: 32086476
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

F Kolonics et al. (2020-01-01), Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions J. Leukoc. Biol., 0(0).
PMID: 32946637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MMA Verstegen et al. (2020-01-01), Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease Scientific Reports, 10(1):21900.
PMID: 33318612
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KC Allan et al. (2020-01-01), Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function Cell Stem Cell, 0(0).
PMID: 33091368
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Rossi et al. (2020-01-01), Characterization of zika virus infection of human fetal cardiac mesenchymal stromal cells PLoS ONE, 15(9):e0239238.
PMID: 32941515
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Chitiashvi et al. (2020-01-01), Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation Nature Cell Biology, 22(12):1436-1446.
PMID: 33257808
Species: Human
Sample Types: cell culture
Applications: Cell Culture

N Jia et al. (2020-01-01), Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets J Cell Mol Med, 0(0).
PMID: 33164313
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Lee et al. (2020-01-01), Combined Poziotinib with Manidipine Treatment Suppresses Ovarian Cancer Stem-Cell Proliferation and Stemness Int J Mol Sci, 21(19).
PMID: 33036254
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EM Holloway et al. (2020-01-01), Mapping Development of the Human Intestinal Niche at Single-Cell Resolution Cell Stem Cell, 0(0).
PMID: 33278341
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Tabari et al. (2020-01-01), Impact of Zika Virus Infection on Human Neural Stem Cell MicroRNA Signatures Viruses, 12(11).
PMID: 33121145
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Bammidi et al. (2020-01-01), Transplantation Efficacy of Human Ciliary Epithelium Cells from Fetal Eye and Lin-ve Stem Cells from Umbilical Cord Blood in the Murine Retinal Degeneration Model of Laser Injury Cell Transplant, 29(0):9636897209460.
PMID: 33023312
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HJ Lee et al. (2020-01-01), PI3K p110&alpha Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells Cancers, 12(9).
PMID: 32899250
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SR Lin et al. (2020-01-01), EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer Oncogene, 0(0).
PMID: 32963351
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Liu et al. (2020-01-01), EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy Theranostics, 10(23):10589-10605.
PMID: 32929368
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CM Alexander et al. (2020-01-01), Alternative splicing and cleavage of GLUT8 Mol Cell Biol, 0(0).
PMID: 33077497
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Lloyd et al. (2020-01-01), Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease Dis Model Mech, 0(0).
PMID: 32958515
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Arriagada et al. (2020-01-01), GOLPH3 Regulates EGFR in T98G Glioblastoma Cells by Modulating Its Glycosylation and Ubiquitylation Int J Mol Sci, 21(22).
PMID: 33238647
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Liang et al. (2020-01-01), P300-dependent acetylation of histone H3 is required for EGFR-mediated HMGA2 transcription in hepatocellular carcinoma Cancer Sci, 0(0).
PMID: 33164305
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ST Magill et al. (2020-01-01), Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma Nat Commun, 11(1):4803.
PMID: 32968068
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EAA Obara et al. (2020-01-01), SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells Nat Commun, 11(1):4709.
PMID: 32948765
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

G Newham et al. (2020-01-01), Polyelectrolyte complex templated synthesis of monodisperse, sub-100ï¿½nm porous silica nanoparticles for cancer targeted and stimuli-responsive drug delivery J Colloid Interface Sci, 0(0).
PMID: 33223243
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

L Song et al. (2020-01-01), Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy Nat Commun, 11(1):5842.
PMID: 33203880
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

YS Hwang et al. (2020-01-01), Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells Nat Commun, 11(1):5656.
PMID: 33168808
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SJ Liu et al. (2020-01-01), Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma Cell Rep, 30(5):1300-1309.e5.
PMID: 32023450
Species: Human
Sample Types: Organoid
Applications: Bioassay

A Di Grazia et al. (2020-01-01), The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 33091622
Species: Human
Sample Types: Organoid
Applications: Bioassay

Z Al-Bakri et al. (2020-01-01), Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood Regenerative Therapy, 15(0):53-63.
PMID: 33426202
Species: Human
Sample Types: Organoid
Applications: Bioassay

MJ Workman et al. (2020-01-01), Modeling Intestinal Epithelial Response to Interferon-&gamma in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids International Journal of Molecular Sciences, 22(1).
PMID: 33396621
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BA Humphries et al. (2020-01-01), Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer Breast Cancer Res., 22(1):60.
PMID: 32503622
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Meinhardt et al. (2020-01-01), Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 32482863
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Li et al. (2020-01-01), The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness Cancers (Basel), 12(6).
PMID: 32549341
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

BN Sheikh et al. (2020-01-01), Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature Nat. Cell Biol., 0(0).
PMID: 32541879
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

M Li et al. (2020-01-01), Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma Acta neuropathologica communications, 8(1):221.
PMID: 33308315
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

T Okubo et al. (2020-01-01), Generation and validation of a PITX2-EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells J. Biol. Chem., 295(11):3456-3465.
PMID: 32034090
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

LM Caballero et al. (2020-01-01), Formation of alginate microspheres prepared by optimized microfluidics parameters for high encapsulation of bioactive molecules Journal of colloid and interface science, 587(0):240-251.
PMID: 33360897
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Na et al. (2020-01-01), MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK Oncogene, 0(0).
PMID: 33293695
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Rajabi et al. (2020-01-01), CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Oncotarget, 11(45):4155-4168.
PMID: 33227047
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Zhong et al. (2020-01-01), Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways Nature Communications, 11(1):6330.
PMID: 33303737
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Huo et al. (2020-01-01), EGFR targeting enhances the efficiency of chemotherapy through inhibiting IRE1alpha-XBP1s pathway in colorectal cancer cells J Cancer, 11(15):4464-4473.
PMID: 32489465
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

JK Khalsa et al. (2020-01-01), Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types Nat Commun, 11(1):3912.
PMID: 32764562
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Wang et al. (2020-01-01), Inhibition of Notch pathway enhances the anti-tumor effect of docetaxel in prostate cancer stem-like cells Stem Cell Res Ther, 11(1):258.
PMID: 32586404
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Wei et al. (2020-01-01), Notch signalling drives synovial fibroblast identity and arthritis pathology Nature, 582(7811):259-264.
PMID: 32499639
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MH Hancock et al. (2020-01-01), Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways mSphere, 5(4).
PMID: 32759334
Species: Human
Sample Types: Organoids
Applications: Bioassay

T Kijima et al. (2019-01-01), Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells Cell Mol Gastroenterol Hepatol, 7(1):73-91.
PMID: 30510992
Species: Human
Sample Types: Organoids
Applications: Bioassay

SJ Yoon et al. (2019-01-01), Reliability of human cortical organoid generation Nat. Methods, 16(1):75-78.
PMID: 30573846
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

S Ranganatha et al. (2019-01-01), Evaluating S. flexneri pathogenesis in the human enteroid model Infect. Immun., 0(0).
PMID: 30642900
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Wang et al. (2019-01-01), Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale PeerJ, 6(0):e6143.
PMID: 30643676
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Chesnokova et al. (2019-01-01), Excess growth hormone suppresses DNA damage repair in epithelial cells JCI Insight, 4(3).
PMID: 30728323
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YQ Guan et al. (2019-01-01), Aging, rather than Parkinson's disease, affects the responsiveness of PBMCs to the immunosuppression of bone marrow mesenchymal stem cells Mol Med Rep, 19(1):165-176.
PMID: 30483752
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Klose et al. (2019-01-01), Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model PLoS ONE, 14(2):e0211916.
PMID: 30763370
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JH Jo et al. (2019-01-01), Novel Gastric Cancer Stem Cell-Related Marker LINGO2 Is Associated with Cancer Cell Phenotype and Patient Outcome Int J Mol Sci, 20(3).
PMID: 30696080
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SZ Kuo et al. (2019-01-01), Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma Int J Mol Sci, 20(1).
PMID: 30621095
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Mandal et al. (2019-01-01), Encapsulated human mesenchymal stem cells (eMSCs) as a novel anti-cancer agent targeting breast cancer stem cells: development of 3D primed therapeutic MSCs Int. J. Biochem. Cell Biol., 0(0).
PMID: 30735730
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Matsui et al. (2019-01-01), Differentiation and isolation of iPSC-derived remodeling ductal plate-like cells by use of an AQP1-GFP reporter human iPSC line Stem Cell Res, 35(0):101400.
PMID: 30735882
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Inoue et al. (2019-01-01), Autonomous trisomic rescue of Down syndrome cells Lab. Invest., 0(0).
PMID: 30760866
Species: Human

Applications: Bioassay

JH Wang et al. (2019-01-01), Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma Cancer Med, 0(0).
PMID: 30741466
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Liu et al. (2019-01-01), Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ Oncogene, 38(1):120-139.
PMID: 30082911
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CY Yang et al. (2019-01-01), Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration Oncogene, 0(0).
PMID: 30696956
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Mastrella et al. (2019-01-01), Targeting APLN/APLNR improves anti-angiogenic efficiency and blunts pro-invasive side effects of VEGFA/VEGFR2-blockade in glioblastoma Cancer Res., 0(0).
PMID: 30718358
Species: Human
Sample Types: Organoids
Applications: Bioassay

TR Broda et al. (2019-01-01), Generation of human antral and fundic gastric organoids from pluripotent stem cells Nat Protoc, 14(1):28-50.
PMID: 30470820
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Bunda et al. (2019-01-01), CIC protein instability contributes to tumorigenesis in glioblastoma Nat Commun, 10(1):661.
PMID: 30737375
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Kano et al. (2019-01-01), Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation Nat Commun, 10(1):224.
PMID: 30644389
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Naldaiz-Ga et al. (2019-01-01), Isolation and characterization of myogenic precursor cells from human cremaster muscle Sci Rep, 9(1):3454.
PMID: 30837559
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Shen et al. (2019-01-01), MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway Cancer Cell Int., 19(0):61.
PMID: 30923463
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MA Ajmone-Cat et al. (2019-01-01), Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death Sci Rep, 9(1):4572.
PMID: 30872738
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Wang et al. (2019-01-01), AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation Oncogene, 0(0).
PMID: 30894683
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Ramchandan et al. (2019-01-01), Nanoparticle delivery of miR-708 mimetic impairs breast cancer metastasis Mol. Cancer Ther., 0(0).
PMID: 30679387
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YP Xu et al. (2019-01-01), Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids Cell Res., 0(0).
PMID: 30814679
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Linkous et al. (2019-01-01), Modeling Patient-Derived Glioblastoma with Cerebral Organoids Cell Rep, 26(12):3203-3211.e5.
PMID: 30893594
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Feng et al. (2019-01-01), Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth Autophagy, 0(0):1-20.
PMID: 30686098
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Ma et al. (2019-01-01), Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation Nat Commun, 10(1):296.
PMID: 30655532
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Wang et al. (2019-01-01), SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis Nat. Cell Biol., 0(0).
PMID: 30692626
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RM Marton et al. (2019-01-01), Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures Nat. Neurosci., 0(0).
PMID: 30692691
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Hall et al. (2019-01-01), RUNX represses Pmp22 to drive neurofibromagenesis Sci Adv, 5(4):eaau8389.
PMID: 31032403
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HL Zhang et al. (2019-01-01), c-Myc maintains the self-renewal and chemoresistance properties of colon cancer stem cells Oncol Lett, 17(5):4487-4493.
PMID: 30944638
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Matsushita et al. (2019-01-01), PTPRK suppresses progression and chemo-resistance of colon cancer cells via direct inhibition of pro-oncogenic CD133 FEBS Open Bio, 0(0).
PMID: 30947381
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Sun et al. (2019-01-01), Co-Transplantation of Human Umbilical Cord Mesenchymal Stem Cells and Human Neural Stem Cells Improves the Outcome in Rats with Spinal Cord Injury Cell Transplant, 0(0):9636897198445.
PMID: 31012325
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JA Bernatchez et al. (2019-01-01), Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells Viruses, 11(4).
PMID: 31010044
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EM Kim et al. (2019-01-01), Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine PLoS Negl Trop Dis, 13(4):e0006843.
PMID: 30943209
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Urbischek et al. (2019-01-01), Organoid culture media formulated with growth factors of defined cellular activity Sci Rep, 9(1):6193.
PMID: 30996238
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S An et al. (2019-01-01), Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies Ocul Surf, 0(0).
PMID: 30965123
Species: Xenograft
Sample Types: Whole Cells
Applications: Bioassay

EE Mulkearns- et al. (2019-01-01), Development of a Cx46 Targeting Strategy for Cancer Stem Cells Cell Rep, 27(4):1062-1072.e5.
PMID: 31018124
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Li et al. (2019-01-01), Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer Cancer Res., 0(0).
PMID: 30952632
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Hirose et al. (2019-01-01), ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration J. Clin. Invest., 130(0).
PMID: 30985297
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Kawai et al. (2019-01-01), ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD PLoS ONE, 14(5):e0216503.
PMID: 31083682
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ML Shiao et al. (2019-01-01), Immunomodulation with Human Umbilical Cord Blood Stem Cells Ameliorates Ischemic Brain Injury - A Brain Transcriptome Profiling Analysis Cell Transplant, 0(0):9636897198367.
PMID: 31066288
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YB Pang et al. (2019-01-01), A Potential Antitumor Effect of Dendritic Cells Fused with Cancer Stem Cells in Hepatocellular Carcinoma Stem Cells Int, 2019(0):5680327.
PMID: 31065274
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

WY Teo et al. (2019-01-01), Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations Sci Rep, 9(1):7442.
PMID: 31092847
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Min et al. (2019-01-01), MICAL-L2 potentiates Cdc42-dependent EGFR stability and promotes gastric cancer cell migration J. Cell. Mol. Med., 0(0).
PMID: 31034158
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

OC Tysoe et al. (2019-01-01), Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue Nat Protoc, 14(6):1884-1925.
PMID: 31110298
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Xiong et al. (2019-01-01), Impaired Regeneration Potential in Urinary Stem Cells Diagnosed from the Patients with Diabetic Nephropathy Theranostics, 9(14):4221-4232.
PMID: 31281543
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Messerschm et al. (2019-01-01), Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation Mol. Vis., 25(0):329-344.
PMID: 31341381
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

MR Wu et al. (2019-01-01), A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS) Nat Commun, 10(1):2880.
PMID: 31253799
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Du et al. (2019-01-01), Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR Theranostics, 9(13):3879-3902.
PMID: 31281520
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Ravi et al. (2019-01-01), Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms PLoS ONE, 14(9):e0221952.
PMID: 31491006
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CY Lee et al. (2019-01-01), High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures Biomed Res Int, 2019(0):4714279.
PMID: 31531354
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CY Su et al. (2019-01-01), Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration Sci Rep, 9(1):13703.
PMID: 31548578
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Shen et al. (2019-01-01), Differentially Expressed microRNAs in MIA PaCa-2 and PANC-1 Pancreas Ductal Adenocarcinoma Cell Lines are Involved in Cancer Stem Cell Regulation Int J Mol Sci, 20(18).
PMID: 31510100
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Kim et al. (2019-01-01), Repurposing Penfluridol in Combination with Temozolomide for the Treatment of Glioblastoma Cancers (Basel), 11(9).
PMID: 31492002
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

L Jin et al. (2019-01-01), CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors Nat Commun, 10(1):4016.
PMID: 31488817
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SFB Fadhlullah et al. (2019-01-01), Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness Oncogene, 38(27):5367-5380.
PMID: 30967630
Species: Human
Sample Types: Organoid, Whole Cells
Applications: Bioassay

KB Jung et al. (2019-01-01), Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells J Clin Med, 8(7).
PMID: 31277507
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Tiihonen et al. (2019-01-01), Neurobiological roots of psychopathy Mol. Psychiatry, 0(0).
PMID: 31455857
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

K Shik Mun et al. (2019-01-01), Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders Nat Commun, 10(1):3124.
PMID: 31311920
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S Mukherjee et al. (2019-01-01), Identification and Classification of Hubs in microRNA Target Gene Networks in Human Neural Stem/Progenitor Cells following Japanese Encephalitis Virus Infection mSphere, 4(5).
PMID: 31578247
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Tabata et al. (2019-01-01), Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas Vaccines (Basel), 7(4).
PMID: 31569508
Species: Human
Sample Types: Tissue Explants
Applications: Cell Culture

YH Lee et al. (2019-01-01), Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling Theranostics, 9(22):6443-6465.
PMID: 31588228
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Chen et al. (2019-01-01), Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion Cancer Res., 0(0).
PMID: 31641031
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Koutmani et al. (2019-01-01), CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus Cell Rep, 29(4):932-945.e7.
PMID: 31644914
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Yung et al. (2019-01-01), Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals Nat Commun, 10(1):4647.
PMID: 31604927
Species: Human
Sample Types: Whole Tissue
Applications: Tissue Culture

AP Singh et al. (2019-01-01), Enteroendocrine progenitor cell enriched miR-7 regulates intestinal epithelial proliferation in an Xiap-dependent manner Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 31756561
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Weber et al. (2019-01-01), The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo BMC Cancer, 19(1):1181.
PMID: 31796022
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Peng et al. (2019-01-01), Neurospheres induced from human adipose-derived stem cells as a new source of neural progenitor cells Cell Transplant, 0(0):9636897198886.
PMID: 31813268
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

GH Son et al. (2019-01-01), MicroRNA-548 regulates high mobility group box 1 expression in patients with preterm birth and chorioamnionitis Sci Rep, 9(1):19746.
PMID: 31875024
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Bueno et al. (2019-01-01), Non-proliferative neurogenesis in human periodontal ligament stem cells Sci Rep, 9(1):18038.
PMID: 31792338
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

D De Silva et al. (2019-01-01), Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen Sci Rep, 9(1):18637.
PMID: 31819114
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KH Grinnemo et al. (2019-01-01), Immunomodulatory effects of interferon-gamma on human fetal cardiac mesenchymal stromal cells Stem Cell Res Ther, 10(1):371.
PMID: 31801632
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B You et al. (2019-01-01), The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients EBioMedicine, 51(0):102574.
PMID: 31877416
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

D Parashar et al. (2019-01-01), miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer Cell Rep, 29(13):4389-4406.e10.
PMID: 31875548
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

D Chen et al. (2019-01-01), Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors Cell Rep, 29(13):4568-4582.e5.
PMID: 31875561
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

L Zhu et al. (2019-01-01), TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis Nat. Cell Biol., 21(12):1604-1614.
PMID: 31792381
Species: Human
Sample Types: Whole Cells
Applications: Stimulation

AA Qayyum et al. (2019-01-01), Cardiac Magnetic Resonance Imaging used for Evaluation of Adipose-Derived Stromal Cell Therapy in Patients with Chronic Ischemic Heart Disease Cell Transplant, 0(0):9636897198835.
PMID: 31698917
Species: Human
Sample Types: Whole Tissue
Applications: Tissue Culture

D Hao et al. (2019-01-01), Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering Stem Cells Int, 2019(0):9695239.
PMID: 31781252
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

C Peng et al. (2019-01-01), Efficient One-Step Induction of Human Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs) Produces MSC-Derived Neurospheres (MSC-NS) with Unique Transcriptional Profile and Enhanced Neurogenic and Angiogenic Secretomes Stem Cells Int, 2019(0):9208173.
PMID: 31933651
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Z Li et al. (2019-01-01), Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells Stem Cell Res Ther, 10(1):324.
PMID: 31730021
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

V Costa et al. (2019-01-01), MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation Cells, 8(12).
PMID: 31771093
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Hu et al. (2019-01-01), Targeting TR4 nuclear receptor with antagonist bexarotene increases docetaxel sensitivity to better suppress the metastatic castration-resistant prostate cancer progression Oncogene, 0(0).
PMID: 31748715
Species: Human
Sample Types: Whole Cell
Applications: Cell Culture

L Yammine et al. (2019-01-01), Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking Cell Rep, 29(7):2067-2077.e6.
PMID: 31722218
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

JK Sa et al. (2019-01-01), Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers Genome Biol., 20(1):253.
PMID: 31771620
Species: Mouse
Sample Types: Cells
Applications: Cell Culture

M Reed et al. (2019-01-01), Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo Nat Commun, 10(1):5004.
PMID: 31676794
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

E Skaga et al. (2019-01-01), Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naï¿½ve glioblastoma BMC Cancer, 19(1):628.
PMID: 31238897
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S Beck et al. (2019-01-01), Mechanism of Action of Methotrexate Against Zika Virus Viruses, 11(4).
PMID: 30974762
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Dreyer-And et al. (2018-01-01), Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells PLoS ONE, 13(1):e0191207.
PMID: 29338033
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Telechea-F et al. (2018-01-01), New localization and function of calpain-2 in nucleoli of colorectal cancer cells in ribosomal biogenesis: effect of KRAS status Oncotarget, 9(10):9100-9113.
PMID: 29507677
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KH Lee et al. (2018-01-01), Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury Stem Cell Res, 31(0):71-78.
PMID: 30031233
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CH Peng et al. (2018-01-01), Acoustic waves improves retroviral transduction in human retinal stem cells J Chin Med Assoc, 0(0).
PMID: 29941298
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Skrzypek et al. (2018-01-01), SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function Cell Death Dis, 9(6):643.
PMID: 29844345
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Wang et al. (2018-01-01), SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition J. Exp. Clin. Cancer Res., 37(1):37.
PMID: 29475441
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JJ Gell et al. (2018-01-01), PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation Stem Cell Res, 27(0):46-56.
PMID: 29324254
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MR Rovere et al. (2018-01-01), Preserving Basement Membranes during Detachment of Cultivated Oral Mucosal Epithelial Cell Sheets for the Treatment of Total Bilateral Limbal Stem Cell Deficiency Cell Transplant, 27(2):264-274.
PMID: 29637812
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YG Kim et al. (2018-01-01), Breast cancer stem cells in HER2-negative breast cancer cells contribute to HER2-mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2-negative breast cancer Oncotarget, 9(5):5811-5822.
PMID: 29464036
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Ihler et al. (2018-01-01), Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma Biomed Res Int, 2018(0):7929104.
PMID: 29693014
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Li et al. (2018-01-01), Ythdf2-mediated m6A mRNA clearance modulates neural development in mice Genome Biol., 19(1):69.
PMID: 29855337
Species: Human
Sample Types: Organoids
Applications: Bioassay

D Garnier et al. (2018-01-01), Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system Sci Rep, 8(1):8222.
PMID: 29844473
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Ding et al. (2018-01-01), Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor Stem Cell Res Ther, 9(1):55.
PMID: 29523193
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Bessa et al. (2018-01-01), Discovery of a small-molecule protein kinase C?-selective activator with promising application in colon cancer therapy Cell Death Dis, 9(2):23.
PMID: 29348560
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PD Leiphrakpa et al. (2018-01-01), TGF? and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancerï¿½cells J. Biol. Chem., 0(0).
PMID: 29599290
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IG Ryoo et al. (2018-01-01), High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance Redox Biol, 17(0):246-258.
PMID: 29729523
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Yang et al. (2018-01-01), Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats Stem Cells Int, 2018(0):4659159.
PMID: 29765412
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MH Choe et al. (2018-01-01), miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP Cell Death Dis, 9(6):640.
PMID: 29844307
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

VNS Garikipati et al. (2018-01-01), Isolation and characterization of mesenchymal stem cells from human fetus heart PLoS ONE, 13(2):e0192244.
PMID: 29420637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Laterza et al. (2018-01-01), Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors PLoS ONE, 13(2):e0192118.
PMID: 29401502
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

JR Fan et al. (2018-01-01), Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model Cell Death Dis, 9(5):502.
PMID: 29717132
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Lahlou et al. (2018-01-01), Modeling human early otic sensory cell development with induced pluripotent stem cells PLoS ONE, 13(6):e0198954.
PMID: 29902227
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Zhang et al. (2018-01-01), HOXD3 Plays a Critical Role in Breast Cancer Stemness and Drug Resistance Cell. Physiol. Biochem., 46(4):1737-1747.
PMID: 29698974
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B Roy et al. (2018-01-01), Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 29735717
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Fueyo et al. (2018-01-01), Lineage specific transcription factors and epigenetic regulators mediate TGF?-dependent enhancer activation Nucleic Acids Res., 0(0).
PMID: 29438503
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Miyamoto et al. (2018-01-01), The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer Cancer Immunol Res, 0(0).
PMID: 29371260
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

GS Wong et al. (2018-01-01), Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition Nat. Med., 0(0).
PMID: 29808010
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EM André et al. (2018-01-01), A novel ex vivo Huntington's disease model for studying GABAergic neurons and cell grafts by laser microdissection PLoS ONE, 13(3):e0193409.
PMID: 29505597
Species: Mouse
Sample Types: Complex Sample Type
Applications: Bioassay

JM Kim et al. (2018-01-01), Voltage-dependent Ca2+ channels promote branching morphogenesis of salivary glands by patterning differential growth Sci Rep, 8(1):7566.
PMID: 29765108
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Wahba et al. (2018-01-01), Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA Oncotarget, 9(1):691-705.
PMID: 29416646
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Porcù et al. (2018-01-01), BMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastoma Cell Death Differ., 0(0).
PMID: 29977042
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Haider et al. (2018-01-01), Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta Stem Cell Reports, 0(0).
PMID: 30078556
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Kirino et al. (2018-01-01), Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition Sci Rep, 8(1):12865.
PMID: 30150715
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JD Blair et al. (2018-01-01), Genetically engineered human cortical spheroid models of tuberous sclerosis Nat. Med., 0(0).
PMID: 30127391
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Q Chen et al. (2018-01-01), Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate MBio, 9(5).
PMID: 30228241
Species: Human
Sample Types: Organoids
Applications: Bioassay

R Cruz-Acuña et al. (2018-01-01), PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery Nat Protoc, 0(0).
PMID: 30190557
Species: Human
Sample Types: Organoids
Applications: Organoid Culture

D Saengwimol et al. (2018-01-01), A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma Sci Rep, 8(1):15664.
PMID: 30353124
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

E Lång et al. (2018-01-01), Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding Nat Commun, 9(1):3665.
PMID: 30202009
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

SA Sloan et al. (2018-01-01), Generation and assembly of human brain region-specific three-dimensional cultures Nat Protoc, 0(0).
PMID: 30202107
Species: Human
Sample Types: Organoids
Applications: Bioassay

C Bonamy et al. (2018-01-01), Expression of the human antimicrobial peptide ?-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells Sci Rep, 8(1):18043.
PMID: 30575780
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Ma et al. (2018-01-01), ? Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus Stem Cell Reports, 0(0).
PMID: 30503261
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Chen et al. (2018-01-01), The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation Cell Rep, 25(13):3591-3602.e5.
PMID: 30590035
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

JY Yeon et al. (2018-01-01), Optimized Clump Culture Methods for Adult Human Multipotent Neural Cells Int J Mol Sci, 19(11).
PMID: 30380605
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Ferrandis et al. (2018-01-01), Dietary fiber sources and non-starch polysaccharide-degrading enzymes modify mucin expression and the immune profile of the swine ileum PLoS ONE, 13(11):e0207196.
PMID: 30408134
Species: Human

Applications: Cell Culture

H Takahashi et al. (2018-01-01), Phosphorylation and inhibition of ceramide kinase by protein kinase C-?: Their changes by serine residue mutations Cell. Signal., 0(0).
PMID: 30448345
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Choi et al. (2018-01-01), Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways Oncogenesis, 7(11):85.
PMID: 30420637
R Negoro et al. (2018-01-01), Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies Stem Cell Reports, 0(0).
PMID: 30472010
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SL Kloet et al. (2018-01-01), NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells Nat Commun, 9(1):4588.
PMID: 30389936
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Wang et al. (2018-01-01), Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer Cell Rep, 25(5):1304-1317.e5.
PMID: 30380420
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ML Schulte et al. (2018-01-01), Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models Nat. Med., 0(0).
PMID: 29334372
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Michael J Workman et al. (2018-01-01), Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips. Cellular and Molecular Gastroenterology and Hepatology, 0(0):2352-345X.
PMID: 29930984
Species: Human
Sample Types: Organoids
Applications: Bioassay

E Sechet et al. (2018-01-01), Natural molecules induce and synergize to boost expression of the human antimicrobial peptide ?-defensin-3 Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30275324
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

M Meng et al. (2018-01-01), Umbilical cord mesenchymal stem cell transplantation in the treatment of multiple sclerosis Am J Transl Res, 10(1):212-223.
PMID: 29423006
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Lee et al. (2018-01-01), Implementation of a Multiplex and Quantitative Proteomics Platform for Assessing Protein Lysates Using DNA-Barcoded Antibodies Mol. Cell Proteomics, 0(0).
PMID: 29531020
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FN Vögtle et al. (2018-01-01), Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood Am. J. Hum. Genet., 0(0).
PMID: 29576218
Species: Human
Sample Types: Organoid
Applications: Bioassay

EE Alexeev et al. (2018-01-01), Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor Am. J. Pathol., 0(0).
PMID: 29454749
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

V Sobrino et al. (2018-01-01), Fast neurogenesis from carotid body quiescent neuroblasts accelerates adaptation to hypoxia EMBO Rep., 0(0).
PMID: 29335248
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Speck et al. (2018-01-01), Targeted BiTE expression by an oncolytic vector augments therapeutic efficacy against solid tumors Clin. Cancer Res., 0(0).
PMID: 29437789
I Pop?na et al. (2018-01-01), Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages Cell Commun. Signal, 16(1):17.
PMID: 29690889
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Poppe et al. (2018-01-01), Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity Stem Cells Transl Med, 0(0).
PMID: 29589874
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Stromecki et al. (2018-01-01), Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma Mol Oncol, 12(4):495-513.
PMID: 29377567
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Saha et al. (2018-01-01), Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models Clin. Cancer Res., 0(0).
PMID: 29599413
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CJ Drummond et al. (2018-01-01), Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors Cancer Cell, 33(1):108-124.e5.
PMID: 29316425
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Fu et al. (2017-01-01), Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity Sci Rep, 7(0):43771.
PMID: 28256562
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Takeda et al. (2017-01-01), Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells Biochem. Biophys. Res. Commun, 0(0).
PMID: 28219643
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FM Khan et al. (2017-01-01), Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures Nat Commun, 8(1):198.
PMID: 28775339
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Sampazioti et al. (2017-01-01), Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells Nat Protoc, 12(4):814-827.
PMID: 28333915
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Yin et al. (2017-01-01), Transglutaminase 2 inhibition reverses mesenchymal transdifferentiation of glioma stem cells by regulating C/EBP? signaling Cancer Res., 0(0).
PMID: 28754668
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

L Xue et al. (2017-01-01), Duration of simulated microgravity affects the differentiation of mesenchymal stem cells Mol Med Rep, 15(5):3011-3018.
PMID: 28339035
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Dietrich et al. (2017-01-01), Bone marrow drives central nervous system regeneration after radiation injury J. Clin. Invest., 0(0).
PMID: 29202481
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

N Sahoo et al. (2017-01-01), Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca(2+) Efflux Channel in the Tubulovesicle Dev. Cell, 41(3):262-273.e6.
PMID: 28486130
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jong Seok Lee (2017-01-01), EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells Yonsei Med. J., 58(1):9-18.
PMID: 27873490
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KF Cogger et al. (2017-01-01), Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun, 8(1):331.
PMID: 28835709
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

H Isshiki et al. (2017-01-01), Establishment of a refined culture method for rat colon organoids Biochem. Biophys. Res. Commun., 0(0).
PMID: 28559141
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

C Zou et al. (2017-01-01), MRI tracking of autologous pancreatic progenitor-derived insulin-producing cells in monkeys Sci Rep, 7(1):2505.
PMID: 28566744
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Hao et al. (2017-01-01), Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors Sci Rep, 7(1):3830.
PMID: 28630494
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Wan et al. (2017-01-01), miR-423-5p knockdown enhances the sensitivity of glioma stem cells to apigenin through the mitochondrial pathway Tumour Biol., 39(4):1010428317695.
PMID: 28381178
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Hino et al. (2017-01-01), Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva J. Clin. Invest., 0(0).
PMID: 28758906
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SW Lee et al. (2017-01-01), Are Adipose-Derived Stem Cells From Liver Falciform Ligaments Another Possible Source of Mesenchymal Stem Cells? Cell Transplant, 26(5):855-866.
PMID: 27938473
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CN Im et al. (2017-01-01), Heat Shock Factor 1 Depletion Sensitizes A172 Glioblastoma Cells to Temozolomide via Suppression of Cancer Stem Cell-Like Properties Int J Mol Sci, 18(2).
PMID: 28241425
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Chijimatsu et al. (2017-01-01), Characterization of Mesenchymal Stem Cell-Like Cells Derived From Human iPSCs via Neural Crest Development and Their Application for Osteochondral Repair Stem Cells Int, 2017(0):1960965.
PMID: 28607560
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NA Guadagno et al. (2017-01-01), Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB Neurobiol. Dis., 103(0):32-44.
PMID: 28363799
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SS Karve et al. (2017-01-01), Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli PLoS ONE, 12(6):e0178966.
PMID: 28614372
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H He et al. (2017-01-01), Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3 Sci Rep, 7(0):43736.
PMID: 28252047
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Almazán-Mo et al. (2017-01-01), Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma Stem Cells Int, 2017(0):7507380.
PMID: 28243259
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Prieur et al. (2017-01-01), Targeting the Wnt pathway and cancer stem cells with anti-progastrin humanized antibodies: a major breakthrough for K-RAS mutated colorectal cancer treatment Clin. Cancer Res., 0(0).
PMID: 28600477
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NV Sankpal et al. (2017-01-01), A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer Oncogene, 0(0).
PMID: 28192403
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Morrison J et al. (2017-01-01), Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis Breast Cancer Res., 19(1):74.
PMID: 28666462
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PH Vincent et al. (2017-01-01), Expression of Pluripotency Markers in Non-pluripotent Human Neural Stem and Progenitor Cells Stem Cells Dev., 0(0).
PMID: 28351210
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JC Niclis et al. (2017-01-01), Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived From Human Induced Pluripotent Stem Cells After Intracerebral Transplantation Stem Cells Transl Med, 0(0).
PMID: 28198124
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Riddick et al. (2017-01-01), A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity Sci Rep, 7(0):43605.
PMID: 28256619
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Birey et al. (2017-01-01), Assembly of functionally integrated human forebrain spheroids Nature, 545(7652):54-59.
PMID: 28445465
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HO King et al. (2017-01-01), RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells Stem Cell Reports, 8(1):125-139.
PMID: 28076755
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

X Wang et al. (2017-01-01), MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells Cancer Res., 0(0).
PMID: 28729418
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Tanaka et al. (2017-01-01), Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation J. Biol. Chem., 0(0).
PMID: 29255092
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Johansen et al. (2017-01-01), Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells Stem Cells Int, 2017(0):9605432.
PMID: 29201062
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Eun et al. (2017-01-01), A cell-autonomous positive-signaling circuit associated with the PDGF-NO-ID4-regulatory axis in glioblastoma cells Biochem. Biophys. Res. Commun, 0(0).
PMID: 28327358
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MJ Son et al. (2017-01-01), Upregulation of mitochondrial NAD(+) levels impairs the clonogenicity of SSEA1(+) glioblastoma tumor-initiating cells Exp. Mol. Med., 49(6):e344.
PMID: 28604662
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Yoshihara et al. (2017-01-01), High-resolution promoter map of human limbal epithelial cells cultured with keratinocyte growth factor and rho kinase inhibitor Sci Rep, 7(1):2845.
PMID: 28588247
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JJ Song et al. (2017-01-01), Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model J. Clin. Invest., 0(0).
PMID: 29227284
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Núñez-Told et al. (2017-01-01), Dental pulp pluripotent-like stem cells (DPPSC), a new stem cell population with chromosomal stability and osteogenic capacity for biomaterials evaluation BMC Cell Biol., 18(1):21.
PMID: 28427322
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Kajiwara et al. (2017-01-01), Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells Stem Cell Reports, 8(6):1701-1713.
PMID: 28591652
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JRW Conway et al. (2017-01-01), Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors Methods, 0(0).
PMID: 28435000
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Liao et al. (2017-01-01), Regulation of stem-like cancer cells by glutamine through ?-catenin pathway mediated by redox signaling Mol. Cancer, 16(1):51.
PMID: 28245869
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Zhou et al. (2017-01-01), Interleukin?6 induces an epithelial?mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration Mol Med Rep, 15(6):4123-4131.
PMID: 28487953
Sample Types: Complex Sample Type

M Imaizumi et al. (2017-01-01), Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering Ann. Otol. Rhinol. Laryngol., 126(4):304-314.
PMID: 28290232
Species: Human
Sample Types: Tissue Homogenates
Applications: Bioassay

E Martínez-S et al. (2017-01-01), Human dental pulp pluripotent-like stem cells promote wound healing and muscle regeneration Stem Cell Res Ther, 8(1):175.
PMID: 28750661
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EK Kim et al. (2017-01-01), Ursodeoxycholic acid inhibits the proliferation of colon cancer cells by regulating oxidative stress and cancer stem-like cell growth PLoS ONE, 12(7):e0181183.
PMID: 28708871
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Kassianido et al. (2017-01-01), Geometry and network connectivity govern the mechanics of stress fibers Proc. Natl. Acad. Sci. U.S.A, 0(0).
PMID: 28213499
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HY Lin et al. (2017-01-01), Fisetin inhibits epidermal growth factor-induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression Mol. Vis., 23(0):900-910.
PMID: 29296070
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Jung et al. (2017-01-01), In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells Nat Commun, 8(0):15680.
PMID: 28604658
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YJ Chen et al. (2017-01-01), Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix Placenta, 0(0).
PMID: 28465002
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Wang et al. (2017-01-01), Aurora A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma J. Cell. Sci, 0(0).
PMID: 28167680
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LJ Fulcher et al. (2017-01-01), Targeting endogenous proteins for degradation through the affinity-directed protein missile system Open Biol, 7(5).
PMID: 28490657
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Xiu Li Ju (2017-01-01), Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats Yonsei Med. J., 58(1):206-216.
PMID: 27873515
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Chen et al. (2017-01-01), Targeting BMI1(+) Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma Cell Stem Cell, 0(0).
PMID: 28285905
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Qiang et al. (2017-01-01), Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Autophagy, 0(0):0.
PMID: 28933598
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KJ Yoon et al. (2017-01-01), Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins Cell Stem Cell, 0(0).
PMID: 28826723
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Li et al. (2017-01-01), KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/?-catenin signalling Nat Commun, 8(0):15146.
PMID: 28440295
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Horibe et al. (2017-01-01), Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy PLoS ONE, 12(3):e0171460.
PMID: 28248963
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DA Casolari et al. (2017-01-01), A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm Sci Rep, 7(1):2467.
PMID: 28550306
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DH Lee et al. (2017-01-01), Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1? in human glioma stem cells Oncotarget, 8(25):40233-40245.
PMID: 28410215
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

X Wang et al. (2017-01-01), Purine synthesis promotes maintenance of brain tumor initiating cells in glioma Nat. Neurosci, 0(0).
PMID: 28346452
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Jung et al. (2017-01-01), Tweety-homologue 1 drives brain colonization of gliomas J. Neurosci., 0(0).
PMID: 28607172
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Wang et al. (2017-01-01), LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells Biochem. Biophys. Res. Commun, 0(0).
PMID: 28238780
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SG Wohl et al. (2017-01-01), Mï¿½ller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture Nat Commun, 8(1):1603.
PMID: 29150673
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Mahati et al. (2017-01-01), TMPRSS4 promotes cancer stem cell traits by regulating CLDN1 in hepatocellular carcinoma Biochem. Biophys. Res. Commun., 0(0).
PMID: 28651932
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Chen et al. (2017-01-01), The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-EGF to active high molecular weight EGF J. Biol. Chem., 0(0).
PMID: 28455445
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Wei et al. (2017-01-01), Coding and noncoding landscape of extracellular RNA released by human glioma stem cells Nat Commun, 8(1):1145.
PMID: 29074968
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Crespo et al. (2017-01-01), Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing Nat. Med., 0(0).
PMID: 28628110
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CN Im (2017-01-01), Combination Treatment with PPAR? Ligand and Its Specific Inhibitor GW9662 Downregulates BIS and 14-3-3 Gamma, Inhibiting Stem-Like Properties in Glioblastoma Cells Biomed Res Int, 2017(0):5832824.
PMID: 28642874
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

O Patel et al. (2017-01-01), Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association Nat Commun, 8(1):1157.
PMID: 29079850
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JO Múnera et al. (2017-01-01), Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling Cell Stem Cell, 0(0).
PMID: 28648364
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CA Valle Oseg et al. (2017-01-01), Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells Cancer Cell Int, 17(0):24.
PMID: 28228690
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CT Kuo et al. (2017-01-01), Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array Sci Rep, 7(1):4363.
PMID: 28663555
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Trott et al. (2017-01-01), Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells Stem Cell Reports, 8(6):1675-1688.
PMID: 28591650
J Worthingto et al. (2017-01-01), Effects of ErbB2 Overexpression on the Proteome and ErbB Ligand-specific Phosphosignaling in Mammary Luminal Epithelial Cells Mol. Cell Proteomics, 16(4):608-621.
PMID: 28174229
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Yu et al. (2017-01-01), Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 28696296
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Zanini et al. (2017-01-01), The tumor suppressor protein OPCML potentiates anti-EGFR and anti-HER2 targeted therapy in HER2-positive ovarian and breast cancer Mol. Cancer Ther., 0(0).
PMID: 28775148
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JX Wang et al. (2017-01-01), GLI2 induces PDGFRB expression and modulates cancer stem cell properties of gastric cancer Eur Rev Med Pharmacol Sci, 21(17):3857-3865.
PMID: 28975979
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Lugert et al. (2017-01-01), Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis Sci Rep, 7(0):46543.
PMID: 28440309
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YC Xu et al. (2017-01-01), Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3K?-selective Inhibitors in Breast Cancer Theranostics, 7(4):974-986.
PMID: 28382169
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PH Lakner et al. (2017-01-01), Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models Sci Rep, 7(0):42730.
PMID: 28211922
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AI Sagredo et al. (2017-01-01), TRPM4 regulates Akt/GSK3-? activity and enhances ?-catenin signaling and cell proliferation in prostate cancer cells Mol Oncol, 0(0).
PMID: 28614631
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jun-Hung Cho et al. (2017-01-01), Notch transactivates Rheb to maintain the multipotency of TSC-null cells. Nature Communications, 0(0):2041-1723.
PMID: 29184052
Species: Human
Sample Types: Spheroid
Applications: Bioassay

N Arora et al. (2017-01-01), A process engineering approach to increase organoid yield Development, 144(6):1128-1136.
PMID: 28174251
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Maria Rossing (2016-01-01), A new NFIA:RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma Cancer Genet, 209(10):440-444.
PMID: 27810072
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma Genome Biol, 17(1):80.
PMID: 27139883
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion Stem Cells, 0(0).
PMID: 27145382
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Martovetsk et al. (2016-01-01), Transcription factor-mediated regulation of kidney versus liver specification of Slc and Abc drug transporters, tight junction molecules and signature biomarkers Drug Metab Dispos, 0(0).
PMID: 27044799
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shiva Mansouri (2016-01-01), Pituitary Adenlylate Cyclase Activating Peptide Protects Adult Neural Stem Cells from a Hypoglycaemic milieu PLoS ONE, 11(6):e0156867.
PMID: 27305000
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer Oncotarget, 0(0).
PMID: 27829216
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xinfang Yu (2016-01-01), Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production Mol. Carcinog, 0(0).
PMID: 27996164
Species: Human
Sample Types: Tissue Homogenates
Applications: Bioassay

(2016-01-01), Brain tissue banking for stem cells for our future Sci Rep, 6(0):39394.
PMID: 27991551
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JK Dermawan et al. (2016-01-01), Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models Cancer Res., 76(8):2432-42.
PMID: 26921329
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

CG Hubert et al. (2016-01-01), A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo Cancer Res., 76(8):2465-77.
PMID: 26896279
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Glucocorticoids Suppress Mitochondrial Oxidant Production via Upregulation of Uncoupling Protein 2 in Hyperglycemic Endothelial Cells PLoS ONE, 11(4):e0154813.
PMID: 27128320
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

(2016-01-01), SPINK6 promotes metastasis of nasopharyngeal carcinoma via binding and activation of epithelial growth factor receptor Cancer Res, 0(0).
PMID: 27671677
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking Nat. Genet., 0(0).
PMID: 27869826
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Margriet A Huisman (2016-01-01), Isolation, expansion and neural differentiation of stem cells from human plucked hair: a further step towards autologous nerve recovery Cytotechnology, 68(5):1849-58.
PMID: 26702932
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neil E Bhola (2016-01-01), Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population Cancer Res, 76(2):440-52.
PMID: 26676751
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer Oncotarget, 0(0).
PMID: 27626181
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling J Cell Sci, 0(0).
PMID: 27505894
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Young Dong Yoo (2016-01-01), Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition EMBO Rep, 0(0).
PMID: 27993939
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sachdev S Sidhu (2016-01-01), A Highly Diverse and Functional Naï¿½ve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents J. Mol. Biol., 0(0).
PMID: 27887869
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lucie Germain (2016-01-01), Improved Methods to Produce Tissue-Engineered Skin Substitutes Suitable for the Permanent Closure of Full-Thickness Skin Injuries Biores Open Access, 5(1):320-329.
PMID: 27872793
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xiaoguang Fang (2016-01-01), Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination J. Exp. Med, 0(0).
PMID: 27923907
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DH Heiland et al. (2016-01-01), c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas Oncotarget, 0(0).
PMID: 28036297
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton's jelly mesenchymal stem cells Stem Cell Res Ther, 7(1):165.
PMID: 27852316
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

(2016-01-01), Growth hormone is permissive for neoplastic colon growth Proc Natl Acad Sci USA, 0(0).
PMID: 27226307
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kristen M Bullard-Fe (2016-01-01), The FDA-approved drug sofosbuvir inhibits Zika virus infection Antiviral Res, 137(0):134-140.
PMID: 27902933
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-01-01), Characterization of Neurogenic Potential of Dental Pulp Stem Cells Cultured in Xeno/Serum-Free Condition: In Vitro and In Vivo Assessment Stem Cells Int, 2016(0):6921097.
PMID: 27688776
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Zhu et al. (2016-01-01), The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages J. Cell Biol., 215(2):187-202.
PMID: 27810911
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wu et al. (2015-01-01), Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer. PLoS ONE, 10(1):e0117510.
PMID: 25629735
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soeda et al. (2015-01-01), The evidence of glioblastoma heterogeneity. Sci Rep, 5(0):7979.
PMID: 25623281
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Salvucci O et al. (2015-01-01), EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun, 6(0):6576.
PMID: 25807892
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xu R et al. (2015-01-01), Arf6 regulates EGF-induced internalization of E-cadherin in breast cancer cells. Cancer Cell Int, 15(1):11.
PMID: 25678857
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bogershausen N et al. (2015-01-01), RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. J Clin Invest, 125(9):3585-99.
PMID: 26280580
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Morrison M et al. (2015-01-01), mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis. PLoS Genet, 11(7):e1005291.
PMID: 26132202
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tabata T et al. (2015-01-01), Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta. J Virol, 89(9):5134-47.
PMID: 25741001
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lee H et al. (2015-01-01), Patient-derived xenografts from non-small cell lung cancer brain metastases are valuable translational platforms for the development of personalized targeted therapy. Clin Cancer Res, 21(5):1172-82.
PMID: 25549722
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jacobsen H et al. (2015-01-01), Pan-HER, an Antibody Mixture Simultaneously Targeting EGFR, HER2, and HER3, Effectively Overcomes Tumor Heterogeneity and Plasticity. Clin Cancer Res, 21(18):4110-22.
PMID: 25908781
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Liang Y et al. (2015-01-01), Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer. Cancer Res, 75(17):3672-80.
PMID: 26141861
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fakhraldeen S et al. (2015-01-01), Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells. J Biol Chem, 290(21):13386-400.
PMID: 25861986
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Song E et al. (2015-01-01), Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity. J Cell Sci, 128(5):913-22.
PMID: 25588829
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

All A et al. (2015-01-01), Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. PLoS ONE, 10(1):e0116933.
PMID: 25635918
Pino-Barrio M et al. (2015-01-01), V-myc immortalizes human neural stem cells in the absence of pluripotency-associated traits. PLoS ONE, 10(3):e0118499.
PMID: 25764185
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Krizbai I et al. (2015-01-01), Endothelial-mesenchymal transition of brain endothelial cells: possible role during metastatic extravasation. PLoS ONE, 10(3):e0119655.
PMID: 25742314
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wong S et al. (2015-01-01), Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion. Cancer Res, 75(6):1113-22.
PMID: 25634210
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sundnes O et al. (2015-01-01), Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences. J Invest Dermatol, 135(7):1771-80.
PMID: 25739051
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ito et al. (2015-01-01), Artificial human Met agonists based on macrocycle scaffolds. Nat Commun, 6(0):6373.
PMID: 25758345
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Braun A et al. (2015-01-01), The Rho-specific GAP protein DLC3 coordinates endocytic membrane trafficking. J Cell Sci, 128(7):1386-99.
PMID: 25673874
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Karaca M et al. (2015-01-01), Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding. PLoS ONE, 10(5):e0126270.
PMID: 25950519
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sarkar P et al. (2015-01-01), Activin/nodal signaling switches the terminal fate of human embryonic stem cell-derived trophoblasts. J Biol Chem, 290(14):8834-48.
PMID: 25670856
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pasdar E et al. (2015-01-01), Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS ONE, 10(5):e0119549.
PMID: 25932953
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lee S et al. (2015-01-01), <