Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human, Mouse, Rat, Chicken |
Immunogen: | Bovine brain corpus callosum white matter |
Applications: | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Label: | Unconjugated |
Source: | Monoclonal Mouse IgM Clone # O4 |
Specificity: |
Detects human, mouse, rat, and chicken Oligodendrocyte Marker O4. |
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Citations for Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 Antibody (78)
Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 Antibody include:
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Species: Human
Sample Types: Whole Cells
Applications: ICCJ Mathews et al. (2022-01-01), Ion Channel Drugs Suppress Cancer Phenotype in NG108-15 and U87 Cells: Toward Novel Electroceuticals for Glioblastoma Cancers, 14(6).
PMID: 35326650 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCS Ghorbani et al. (2022-01-01), Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination Nature Communications, 13(1):2445.
PMID: 35508608 -
Species: Rabbit
Sample Types: Whole Cells
Applications: ICCBA Kühne et al. (2022-01-01), Docosahexaenoic Acid and Melatonin Prevent Impaired Oligodendrogenesis Induced by Intrauterine Growth Restriction (IUGR) Biomedicines, 10(5).
PMID: 35625940 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCR Kuwayama et al. (2022-01-01), Establishment of mouse model of inherited PIGO deficiency and therapeutic potential of AAV-based gene therapy Nature Communications, 13(1):3107.
PMID: 35661110 -
Species: Human
Sample Types: Whole Cells
Applications: ICCD de Souza D et al. (2022-01-01), The Neural Multilineage Differentiation Capacity of Human Neural Precursors from the Umbilical Cord-Ready to Bench for Clinical Trials Membranes, 12(9).
PMID: 36135892 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCF Zhang et al. (2022-01-01), MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats Brain research bulletin, 0(0).
PMID: 35985609 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotER Aber et al. (2022-01-01), Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death Cell Reports, 41(3):111480.
PMID: 36261002 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCC Bernhardt et al. (2022-01-01), KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF Nucleic Acids Research, 0(0).
PMID: 36318265 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCY Zhao et al. (2022-01-01), Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice Nature Communications, 13(1):6813.
PMID: 36357389 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCM Schepers et al. (2022-01-01), Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis Brain, Behavior, and Immunity, 109(0):1-22.
PMID: 36584795 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCT Dierckx et al. (2022-01-01), Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation Proceedings of the National Academy of Sciences of the United States of America, 119(46):e2120393119.
PMID: 36343243 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCJA Lindborg et al. (2021-01-01), Optic nerve regeneration screen identifies multiple genes restricting adult neural repair Cell Reports, 34(9):108777.
PMID: 33657370 -
Species: Human
Sample Types: Whole Cells
Applications: ICCA Manousi et al. (2021-01-01), Identification of novel myelin repair drugs by modulation of oligodendroglial differentiation competence EBioMedicine, 65(0):103276.
PMID: 33714029 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCR Fujii-Tezu et al. (2021-01-01), Umbilical artery tissue contains p75 neurotrophin receptor-positive pericyte-like cells that possess neurosphere formation capacity and neurogenic differentiation potential Regenerative Therapy, 16(0):1-11.
PMID: 33426237 -
Species: Rat
Sample Types: Whole Cells
Applications: IHCT Shimizu et al. (2021-01-01), Tension Sensor Based on Fluorescence Resonance Energy Transfer Reveals Fiber Diameter-Dependent Mechanical Factors During Myelination Frontiers in Cellular Neuroscience, 15(0):685044.
PMID: 34408628 -
Species: Human
Sample Types: Spheroid
Applications: ICCM Chesnut et al. (2021-01-01), Human IPSC-Derived Model to Study Myelin Disruption International Journal of Molecular Sciences, 22(17).
PMID: 34502381 -
Species: Human
Sample Types: Whole Cells
Applications: ImmunopanningA Nolle et al. (2021-01-01), Enrichment of Glial Cells From Human Post-mortem Tissue for Transcriptome and Proteome Analysis Using Immunopanning Frontiers in Cellular Neuroscience, 15(0):772011.
PMID: 34966261 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCM Yazdankhah et al. (2021-01-01), BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes Autophagy, 0(0):1-20.
PMID: 33404293 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryWU Park et al. (2021-01-01), A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation) Biology, 10(12).
PMID: 34943169 -
Species: Human
Applications: IFN Micali et al. (2020-01-01), Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates Cell Rep, 31(5):107599.
PMID: 32375049 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCM Wedel et al. (2020-01-01), Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation Nucleic Acids Res., 48(9):4839-4857.
PMID: 32266943 -
Species: Human
Sample Types: Whole Cells
Applications: ICCT Hoshino et al. (2020-01-01), Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line FEBS Open Bio, 0(0).
PMID: 32608563 -
Species: Human
Sample Types: Whole Cells
Applications: ICCJA García-Leó et al. (2020-01-01), Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells Nat Protoc, 15(11):3716-3744.
PMID: 33097924 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCK Kleszka et al. (2020-01-01), Hypoxia-inducible factor-2&alpha is crucial for proper brain development Sci Rep, 10(1):19146.
PMID: 33154420 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCE Furube et al. (2020-01-01), Neural stem cell phenotype of tanycyte-like ependymal cells in the circumventricular organs and central canal of adult mouse brain Sci Rep, 10(1):2826.
PMID: 32071335 -
Species: Human
Sample Types: Whole Cells
Applications: ICCZ Al-Bakri et al. (2020-01-01), Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood Regenerative Therapy, 15(0):53-63.
PMID: 33426202 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCQL Cui et al. (2020-01-01), Effects of Biotin on survival, ensheathment, and ATP production by oligodendrocyte lineage cells in vitro PLoS ONE, 15(5):e0233859.
PMID: 32470040 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCJD Bernstock et al. (2019-01-01), SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke EBioMedicine, 0(0).
PMID: 30905846 -
Species: Human
Sample Types: Whole Cells
Applications: ICCRM Marton et al. (2019-01-01), Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures Nat. Neurosci., 0(0).
PMID: 30692691 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-FrN Baba et al. (2019-01-01), Induction of regional chemokine expression in response to human umbilical cord blood cell infusion in the neonatal mouse ischemia-reperfusion brain injury model PLoS ONE, 14(9):e0221111.
PMID: 31483787 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCB Neumann et al. (2019-01-01), Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells Cell Stem Cell, 25(4):473-485.e8.
PMID: 31585093 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCK Thümmler et al. (2019-01-01), Polarizing receptor activation dissociates fibroblast growth factor 2 mediated inhibition of myelination from its neuroprotective potential Acta Neuropathol Commun, 7(1):212.
PMID: 31856924 -
P Piatek et al. (2019-01-01), MS CD49d+CD154+ Lymphocytes Reprogram Oligodendrocytes into Immune Reactive Cells Affecting CNS Regeneration Cells, 8(12).
PMID: 31775315 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCCP Yang et al. (2018-01-01), Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes Nat Commun, 9(1):838.
PMID: 29483533 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCCV Latchouman et al. (2018-01-01), Chronic Electrical Stimulation Promotes the Excitability and Plasticity of ESC-derived Neurons following Glutamate-induced Inhibition In vitro Sci Rep, 8(1):10957.
PMID: 30026496 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCO Le et al. (2018-01-01), INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice Stem Cell Reports, 0(0).
PMID: 29706499 -
Species: Rat
Sample Types: Whole Cells
Applications: IHCX Yu et al. (2018-01-01), N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination Sci Rep, 8(1):14040.
PMID: 30232349 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCYE Guo et al. (2018-01-01), Vitamin C promotes oligodendrocytes generation and remyelination Glia, 0(0).
PMID: 29423921 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCH Zhang et al. (2017-01-01), Erythropoietin signaling increases neurogenesis and oligodendrogenesis of endogenous neural stem cells following spinal cord injury both in�vivo and in�vitro Mol Med Rep, 0(0).
PMID: 29115443 -
Species: Mouse
Sample Types: Whole Cells
Applications: Flow CytometryA Voronova et al. (2017-01-01), Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain Neuron, 94(3):500-516.e9.
PMID: 28472653 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCJR Plemel et al. (2017-01-01), Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis J. Cell Biol, 0(0).
PMID: 28264914 -
Species: Human
Sample Types: Whole Cells
Applications: ICCK Dach et al. (2017-01-01), BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action Sci Rep, 7(0):44861.
PMID: 28317842 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryJH Lee et al. (2017-01-01), Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency Cell Rep, 19(1):20-35.
PMID: 28380358 -
Species: Human
Sample Types: Whole Cells
Applications: ICCT Yamashita et al. (2017-01-01), Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells PLoS ONE, 12(2):e0171947.
PMID: 28192470 -
Species: Mouse
Sample Types: Whole Cells
Applications: Flow CytometryL Leiss et al. (2017-01-01), Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts BMC Cancer, 17(1):108.
PMID: 28173797 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCMY Cha et al. (2017-01-01), Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce A? Deposition in a Mouse Model of Alzheimer's Disease Stem Cells Transl Med, 6(1):293-305.
PMID: 28170178 -
Species: Human
Sample Types: Whole Cells
Applications: ICCJ Kon¡?ov et al. (2017-01-01), Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisions Sci Rep, 7(0):41597.
PMID: 28134287 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICC(2016-01-01), Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica J Neuroinflammation, 13(1):301.
PMID: 27905992 -
Species: Mouse
Sample Types: Whole Cells
Applications: IHC(2016-01-01), Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord Stem Cells, 0(0).
PMID: 27573615 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P(2016-01-01), Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation Nat. Genet., 0(0).
PMID: 27841882 -
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-Fr(2016-01-01), Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis Sci Rep, 6(0):38108.
PMID: 27905510 -
Species: Mouse
Sample Types: Whole Cells
Applications: IHCArulmoli J et al. (2015-01-01), Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner. Sci Rep, 5(0):8499.
PMID: 25686615 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCHu S et al. (2014-01-01), Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. PLoS ONE, 9(8):e105219.
PMID: 25133679 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMitchell R et al. (2014-01-01), Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors. Stem Cells, 32(8):2178-87.
PMID: 24740884 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryHerrmann A et al. (2014-01-01), TLR9 is critical for glioma stem cell maintenance and targeting. Cancer Res, 74(18):5218-28.
PMID: 25047528 -
Species: Human
Sample Types: Whole Cells
Applications: IHC-FrLeite C et al. (2014-01-01), Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage. PLoS ONE, 9(10):e111059.
PMID: 25357129 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCSkardelly M et al. (2014-01-01), Fluorescent protein-expressing neural progenitor cells as a tool for transplantation studies. PLoS ONE, 9(6):e99819.
PMID: 24932758 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSilva N et al. (2013-01-01), Combining adult stem cells and olfactory ensheathing cells: the secretome effect. Stem Cells Dev, 22(8):1232-40.
PMID: 23316915 -
Species: Human
Sample Types: Whole Cells
Applications: ICCGuo et al. (2013-01-01), An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway. J Neurosci, 33(14):6181-90.
PMID: 23554499 -
Species: Human
Sample Types: Whole Cells
Applications: ICCWang et al. (2013-01-01), Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. PLoS ONE, 8(11):e81720.
PMID: 24303066 -
Species: Human
Sample Types: Whole Cells
Applications: ICCYamaguchi Y et al. (2013-01-01), Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage. J Biol Chem, 288(5):3097-111.
PMID: 23204518 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCHe LF et al. (2010-01-01), Curcumin protects pre-oligodendrocytes from activated microglia in vitro and in vivo. Brain Res., 1339(0):60-9.
PMID: 20403340 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCMargaryan G et al. (2009-01-01), Extracellular magnesium enhances the damage to locomotor networks produced by metabolic perturbation mimicking spinal injury in the neonatal rat spinal cord in vitro. Neuroscience, 163(2):669-82.
PMID: 19591902 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCYu SW et al. (2008-01-01), Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. Stem Cells, 26(10):2602-10.
PMID: 18653772 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCNicoleau C et al. (2008-01-01), Endogenous hepatocyte growth factor is a niche signal for subventricular zone neural stem cell amplification and self-renewal. Stem Cells, 0(0).
PMID: 18988709 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSun Y et al. (2008-01-01), Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Mol. Cell. Neurosci., 38(2):245-58.
PMID: 18450476 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCRuau D et al. (2008-01-01), Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. Stem Cells, 26(4):920-6.
PMID: 18203677 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCGalabova-Kovacs G et al. (2008-01-01), Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development. J. Cell Biol., 180(5):947-55.
PMID: 18332218 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCHong S et al. (2007-01-01), Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. Mol. Ther., 15(9):1630-9.
PMID: 17609656 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCGossrau G et al. (2007-01-01), Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells. Stem Cells, 25(4):939-49.
PMID: 17218404 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCChang MY et al. (2007-01-01), Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells. Mol. Cell. Biol., 27(12):4293-305.
PMID: 17438128 -
Species: Human
Sample Types: Whole Cells
Applications: ICCHong S et al. (2007-01-01), Neural precursors derived from human embryonic stem cells maintain long-term proliferation without losing the potential to differentiate into all three neural lineages, including dopaminergic neurons. J. Neurochem., 104(2):316-24.
PMID: 17944878 -
Species: Human
Sample Types: Whole Cells
Applications: ICCKang SM et al. (2006-01-01), Efficient induction of oligodendrocytes from human embryonic stem cells. Stem Cells, 25(2):419-24.
PMID: 17053214 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCZhang PL et al. (2006-01-01), Increased myelinating capacity of embryonic stem cell derived oligodendrocyte precursors after treatment by interleukin-6/soluble interleukin-6 receptor fusion protein. Mol. Cell. Neurosci., 31(3):387-98.
PMID: 16325417 -
Species: Human
Sample Types: Whole Cells
Applications: ICCBenzing C et al. (2006-01-01), Neural conversion of human embryonic stem cell colonies in the presence of fibroblast growth factor-2. Neuroreport, 17(16):1675-81.
PMID: 17047452 -
Species: Human
Sample Types: Whole Cells
Applications: ICCPorat Y et al. (2006-01-01), Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages. Br. J. Haematol., 135(5):703-14.
PMID: 17052254 -
Species: Human
Sample Types: Whole Cells
Applications: ICCNi HT et al. (2004-01-01), High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells. Brain Res. Dev. Brain Res., 152(2):159-69.
PMID: 15351504 -
Species: Chicken
Sample Types: Whole Cells
Applications: ICCTsai HH et al. (2003-01-01), Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal. Development, 130(10):2095-105.
PMID: 12668624
There are no citations that match your criteria.
Customer Reviews for Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 Antibody (5)
Customer Images
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Application: ICC/IFSample Tested: Glial cellsSpecies: MouseVerified Customer | Posted 12/06/2021
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Application: ICCSample Tested: OligodendrocytesSpecies: RatVerified Customer | Posted 07/16/2019ICC without detergents
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Application: ICC/IFSample Tested: Adult brainSpecies: MouseVerified Customer | Posted 04/16/2019
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Application: ICC/IFSample Tested: IPS2 induced pluripotent stem cellsSpecies: MouseVerified Customer | Posted 01/25/2018
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Application: ICC/IFSample Tested: Neural progenitor cellsSpecies: MouseVerified Customer | Posted 12/15/2016Our research focuses on how neural stem cells make the choice to differentiate into the various adult lineages such as neurons, astrocytes, and oligodendrocytes. We utilize the O4 oligodendrocyte marker as a tool to label differentiated oligodendrocytes and assess oligogenesis in various microenvironments.
There are no reviews that match your criteria.