Recombinant Human Noggin Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | NS0 |
Accession #: | Q13253 |
Structure / Form: |
Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations for Recombinant Human Noggin Protein (174)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human Noggin Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayK Uehara et al. (2022), Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids Stem Cell Reports, 0(0).
PMID: 35245440 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2022), ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation Autophagy, 0(0).
PMID: 35311460 -
Species: Human
Sample Types: Organoid
Applications: BioassayS Vachenc et al. (2022), OncoSNIPE� Study Protocol, a study of molecular profiles associated with development of resistance in solid cancer patients BMC Cancer, 22(1):41.
PMID: 34991520 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Zhao et al. (2022), Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells Cell Transplantation, 31(0):9636897211066.
PMID: 35156411 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJM Suárez-Riv et al. (2022), Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases Frontiers in Pharmacology, 13(0):862085.
PMID: 35370630 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Kim et al. (2022), Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids Nature Communications, 13(1):1692.
PMID: 35354790 -
Species: Human
Sample Types: Organoids
Applications: BioassayYH Go et al. (2022), Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts Cancers, 14(9).
PMID: 35565206 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayS Ding et al. (2022), Patient-derived micro-organospheres enable clinical precision oncology Cell Stem Cell, 0(0).
PMID: 35508177 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Ohgushi et al. (2022), Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model Cell Reports, 39(12):110973.
PMID: 35732132 -
Species: Equine
Sample Types: Organoid
Applications: BioassayRE Thompson et al. (2022), Equine Oviductal Organoid Generation and Cryopreservation Methods and protocols, 5(3).
PMID: 35736552 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureK Kishimoto et al. (2022), Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems Nature Protocols, 0(0).
PMID: 35978039 -
Species: Frog
Applications: BioassayK Johnson et al. (2022), Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions BMC Genomics, 23(1):723.
PMID: 36273135 -
Species: Human
Sample Types: Organoid
Applications: BioassayH Marei et al. (2022), Antibody targeting of E3 ubiquitin ligases for receptor degradation Nature, 610(7930):182-189.
PMID: 36131013 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Kuwahara et al. (2022), Fluvastatin promotes chondrogenic differentiation of adipose-derived mesenchymal stem cells by inducing bone morphogenetic protein 2 Bmc Pharmacology Toxicology, 2022;23(1):61.
PMID: 35945639 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKJ Ng et al. (2022), Sox2 in the dermal papilla regulates hair follicle pigmentation Oncogene, 40(3):111100.
PMID: 35858560 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Akrioti et al. (2022), Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson's Disease Biomolecules, 12(7).
PMID: 35883433 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayESY Ng et al. (2022), Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration Cells, 11(21).
PMID: 36359858 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Iannielli et al. (2022), Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications Cell Death Disease, 2022;13(10):881.
PMID: 36261424 -
Species: Feline
Sample Types: Organoids
Applications: BioassayRE Thompson et al. (2022), Generation and cryopreservation of feline oviductal organoids Theriogenology, 196(0):167-173.
PMID: 36423511 -
Species: N/A
Sample Types: Plasmid
Applications: BioassayV Haellman et al. (2021), Rational design and optimization of synthetic gene switches for controlling cell-fate decisions in pluripotent stem cells Metabolic engineering, 65(0):99-110.
PMID: 33744461 -
Species: Porcine
Sample Types: Organoids
Applications: BioassayB Vermeire et al. (2021), Porcine small intestinal organoids as a model to explore ETEC-host interactions in the gut Veterinary research, 52(1):94.
PMID: 34174960 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Brookhouse et al. (2021), APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease Molecular Psychiatry, 0(0).
PMID: 33837271 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMDA Norman et al. (2021), Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy Nature Protocols, 0(0).
PMID: 33854255 -
Species: Equine
Sample Types: Organoid
Applications: BioassayS Hellman (2021), Generation of equine enteroids and enteroid-derived 2D monolayers that are responsive to microbial mimics Veterinary research, 52(1):108.
PMID: 34391473 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Bai et al. (2021), Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts Stem Cell Research, 56(0):102507.
PMID: 34454392 -
Species: Human
Sample Types: Organoid
Applications: BioassayO Hoare et al. (2021), Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models Cancers, 13(10).
PMID: 34069519 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Ali et al. (2021), Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty Stem Cell Reports, 0(0).
PMID: 34358452 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Merlevede et al. (2021), A quantitative model of cellular decision making in direct neuronal reprogramming Scientific Reports, 11(1):1514.
PMID: 33452356 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Yucer et al. (2021), Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis Cell Reports, 37(13):110146.
PMID: 34965417 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Sharma et al. (2021), Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model Nature Communications, 12(1):7293.
PMID: 34911940 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayB Orr et al. (2021), Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer Veterinary research, 52(1):142.
PMID: 34819162 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Bruzelius et al. (2021), Reprogramming Human Adult Fibroblasts into GABAergic Interneurons Cells, 10(12).
PMID: 34943958 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAK Eicher et al. (2021), Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells Cell Stem Cell, 0(0).
PMID: 34856121 -
Species: Human
Sample Types: Organoid
Applications: BioassayY Cheng et al. (2021), Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease EBioMedicine, 75(0):103758.
PMID: 34933179 -
Species: Human
Sample Types: Organoid
Applications: BioassayR Nicolle et al. (2021), Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer Translational Oncology, 16(0):101315.
PMID: 34906890 -
Species: Human
Sample Types: Organoid
Applications: BioassayV Chesnokova et al. (2021), Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage Cell Reports, 37(11):110068.
PMID: 34910915 -
Species: Human
Sample Types: Organoid
Applications: BioassaySK Sarvestani et al. (2021), Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity Nature Communications, 12(1):262.
PMID: 33431859 -
Species: Human
Sample Types: Organoid
Applications: BioassayBM Larsen et al. (2021), A pan-cancer organoid platform for precision medicine Cell Reports, 36(4):109429.
PMID: 34320344 -
Species: Human
Sample Types: Organoid
Applications: BioassayH Nakashima et al. (2021), MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling Cell Reports, 35(7):109124.
PMID: 34010654 -
Species: Human
Sample Types: Organoid
Applications: BioassayK Husain et al. (2021), Farnesyl dimethyl chromanol targets colon cancer stem cells and prevents colorectal cancer metastasis Scientific Reports, 11(1):2185.
PMID: 33500430 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Yoshida et al. (2020), Generation of intestinal organoids derived from human pluripotent stem cells for drug testing Sci Rep, 10(1):5989.
PMID: 32249832 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureA Gunne-Brad et al. (2020), GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells Cell Stem Cell, 26(5):693-706.e9.
PMID: 32302522 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNK Vinckier et al. (2020), LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development Nat Commun, 11(1):2082.
PMID: 32350257 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureS Forostyak et al. (2020), Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats International Journal of Molecular Sciences, 21(24).
PMID: 33339362 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Han et al. (2020), Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis Nat Commun, 11(1):4158.
PMID: 32855417 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAB Caldwell et al. (2020), Dedifferentiation and neuronal repression define familial Alzheimer's disease Sci Adv, 6(46).
PMID: 33188013 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Giacomoni et al. (2020), Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons Cells, 9(11).
PMID: 33182669 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Lloyd et al. (2020), Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease Dis Model Mech, 0(0).
PMID: 32958515 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureJ Meisig et al. (2020), Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation Nucleic Acids Res, 0(0).
PMID: 33245762 -
Species: Human
Sample Types: Organoid
Applications: BioassayA Di Grazia et al. (2020), The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 33091622 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Zhang et al. (2020), Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 0(0).
PMID: 32783886 -
Species: Human
Sample Types: Organoid
Applications: BioassayMJ Workman et al. (2020), Modeling Intestinal Epithelial Response to Interferon-&gamma in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids International Journal of Molecular Sciences, 22(1).
PMID: 33396621 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zheng et al. (2020), A microfluidics-based stem cell model of early post-implantation human development Nature Protocols, 0(0).
PMID: 33311712 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Nolbrant et al. (2020), Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons Stem Cell Reports, 0(0).
PMID: 32976765 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Han et al. (2020), Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis Nat Commun, 11(1):4158.
PMID: 32855417 -
Species: Human
Sample Types: Organoid
Applications: BioassayL Zhang et al. (2020), Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 0(0).
PMID: 32783886 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Ruzicka et al. (2019), The Effect of iPS-Derived Neural Progenitors Seeded on Laminin-Coated pHEMA-MOETACl Hydrogel with Dual Porosity in a Rat Model of Chronic Spinal Cord Injury Cell Transplant, 0(0):9636897188237.
PMID: 30654639 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySTJ Bradford et al. (2019), High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds J. Biol. Chem., 0(0).
PMID: 30602563 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Chesnokova et al. (2019), Excess growth hormone suppresses DNA damage repair in epithelial cells JCI Insight, 4(3).
PMID: 30728323 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Iwashita et al. (2019), Brain-stiffness-mimicking tilapia collagen gel promotes the induction of dorsal cortical neurons from human pluripotent stem cells Sci Rep, 9(1):3068.
PMID: 30816128 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAR Field et al. (2019), Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes Stem Cell Reports, 12(2):245-257.
PMID: 30639214 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTR Broda et al. (2019), Generation of human antral and fundic gastric organoids from pluripotent stem cells Nat Protoc, 14(1):28-50.
PMID: 30470820 -
Species: Human
Sample Types: Whole Cells
Applications: DifferentiationX Wang et al. (2019), Point mutations in the PDX1 transactivation domain impair human ?-cell development and function Mol Metab, 0(0).
PMID: 30930126 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayAJ Miller et al. (2019), Generation of lung organoids from human pluripotent stem cells in vitro Nat Protoc, 14(2):518-540.
PMID: 30664680 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAM Blázquez-M et al. (2019), Noggin depletion in adipocytes promotes obesity in mice Mol Metab, 0(0).
PMID: 31027994 -
Species: Human
Sample Types: Organoid
Applications: BioassayKB Jung et al. (2019), Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells J Clin Med, 8(7).
PMID: 31277507 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Lungova et al. (2019), Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure Nat Commun, 10(1):4161.
PMID: 31551422 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKB Jung et al. (2019), Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells J Clin Med, 8(7).
PMID: 31277507 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureK Shik Mun et al. (2019), Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders Nat Commun, 10(1):3124.
PMID: 31311920 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zheng et al. (2019), Controlled modelling of human epiblast and amnion development using stem cells Nature, 573(7774):421-425.
PMID: 31511693 -
Species: Human
Sample Types: Whole Cells
Applications: Tissue CultureR Sachdeva et al. (2019), BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma Sci Rep, 9(1):14569.
PMID: 31602000 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Omi et al. (2019), Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD signaling pathway J. Biol. Chem., 0(0).
PMID: 31619522 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayJ Piccand et al. (2019), Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while�repressing genetic programs controlling�serotonin production Mol Metab, 29(0):24-39.
PMID: 31668390 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Veschi et al. (2019), Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant Oncogene, 0(0).
PMID: 31591478 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Liang et al. (2019), Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells Stem Cells, 0(0).
PMID: 31648393 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Tripathi et al. (2019), Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination Cell Rep, 29(4):904-919.e9.
PMID: 31644912 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Yung et al. (2019), Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals Nat Commun, 10(1):4647.
PMID: 31604927 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Liu et al. (2019), Differential susceptibility of human neural progenitors and neurons to ischaemic injury Brain Res. Bull., 156(0):25-32.
PMID: 31837459 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Hyakumura et al. (2019), Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices Stem Cells Int, 2019(0):8419493.
PMID: 31827535 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayAP Marshall et al. (2019), Medial artery calcification increases neointimal hyperplasia after balloon injury Sci Rep, 9(1):8193.
PMID: 31160618 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJE Ahlfors et al. (2019), Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells Stem Cell Res Ther, 10(1):166.
PMID: 31196173 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Markouli et al. (2019), Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-?-Dependent Neuroectodermal Commitment Stem Cell Reports, 13(1):163-176.
PMID: 31178415 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKE Tumelty et al. (2018), Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein-Gremlin signaling pathways J. Biol. Chem., 0(0).
PMID: 29317497 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoS Chen et al. (2018), DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis Stem Cell Res Ther, 9(1):185.
PMID: 29973283 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Amin et al. (2018), Cardiotrophic Growth Factor-Driven Induction of Human Muse Cells Into Cardiomyocyte-Like Phenotype Cell Transplant, 27(2):285-298.
PMID: 29637816 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayB Memon et al. (2018), Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1 Stem Cell Res Ther, 9(1):15.
PMID: 29361979 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Wang et al. (2018), Genome-wide analysis of PDX1 target genes in human pancreatic progenitors Mol Metab, 0(0).
PMID: 29396371 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMJ Workman et al. (2018), Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips Cell Mol Gastroenterol Hepatol, 5(4):669-677.e2.
PMID: 29930984 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKKB Tan et al. (2018), Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Sci Rep, 8(1):9567.
PMID: 29934644 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGM D'Abaco et al. (2018), Graphene foam as a biocompatible scaffold for culturing human neurons R Soc Open Sci, 5(3):171364.
PMID: 29657752 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Zambelli et al. (2018), Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells Stem Cell Reports, 0(0).
PMID: 29910126 -
Species: Human
VM Jovanovic et al. (2018), BMP/SMAD pathway promotes neurogenesis of midbrain dopaminergic neurons in vivo and in human induced pluripotent and neural stem cells J. Neurosci., 0(0).
PMID: 29321139 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayI Espuny-Cam et al. (2018), Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way Cell Rep, 23(9):2732-2743.
PMID: 29847802 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Li et al. (2018), Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC Nucleic Acids Res., 0(0).
PMID: 29394393 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Liu et al. (2018), Derivation of phenotypically diverse neural culture from hESC by combining adherent and dissociation methods J. Neurosci. Methods, 0(0).
PMID: 30003885 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Haider et al. (2018), Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta Stem Cell Reports, 0(0).
PMID: 30078556 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Scavuzzo et al. (2018), Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis Nat Commun, 9(1):3356.
PMID: 30135482 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJD Blair et al. (2018), Genetically engineered human cortical spheroid models of tuberous sclerosis Nat. Med., 0(0).
PMID: 30127391 -
Species: Human
Sample Types: Organoids
Applications: BioassayR Cruz-Acuña et al. (2018), PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery Nat Protoc, 0(0).
PMID: 30190557 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2018), 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling Cell Stem Cell, 0(0).
PMID: 30244870 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Li et al. (2018), A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family PLoS ONE, 13(12):e0208110.
PMID: 30540809 -
Species: Human
Sample Types: Organoids
Applications: BioassayC Bonamy et al. (2018), Expression of the human antimicrobial peptide ?-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells Sci Rep, 8(1):18043.
PMID: 30575780 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMA Scavuzzo et al. (2018), Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA Cell Rep, 25(13):3811-3827.e7.
PMID: 30590051 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Bayó-Puxan et al. (2018), Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons Sci Rep, 8(1):16644.
PMID: 30413728 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMichael J Workman et al. (2018), Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips. Cellular and Molecular Gastroenterology and Hepatology, 0(0):2352-345X.
PMID: 29930984 -
Species: Human
Sample Types: Organoids
Applications: BioassayE Sechet et al. (2018), Natural molecules induce and synergize to boost expression of the human antimicrobial peptide ?-defensin-3 Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30275324 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Buskin et al. (2018), Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa Nat Commun, 9(1):4234.
PMID: 30315276 -
Species: Human
Sample Types: Organoid
Applications: BioassayEE Alexeev et al. (2018), Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor Am. J. Pathol., 0(0).
PMID: 29454749 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySV Hegarty et al. (2017), Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation Sci Rep, 7(1):8568.
PMID: 28819210 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJO Múnera et al. (2017), Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling Cell Stem Cell, 0(0).
PMID: 28648364 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Raja et al. (2017), Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells Oncogene, 0(0).
PMID: 28459464 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Baronchell et al. (2017), Epigenetic and transcriptional modulation of WDR5, a chromatin remodeling protein, in Huntington's disease human induced pluripotent stem cell (hiPSC) model Mol. Cell. Neurosci., 82(0):46-57.
PMID: 28476540 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Avaliani et al. (2017), Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Stem Cells Int, 2017(0):5718608.
PMID: 29317869 -
Species: Zebrafish
Sample Types: Whole Tissue
Applications: BioassayOH Ocaña et al. (2017), A right-handed signalling pathway drives heart looping in vertebrates Nature, 549(7670):86-90.
PMID: 28880281 -
Species: Primate
Sample Types: Whole Cells
Applications: BioassayT Yamashita et al. (2017), Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells PLoS ONE, 12(2):e0171947.
PMID: 28192470 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Drouin-Oue et al. (2017), REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways EMBO Mol Med, 9(8):1117-1131.
PMID: 28646119 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Shao et al. (2017), A pluripotent stem cell-based model for post-implantation human amniotic sac development Nat Commun, 8(1):208.
PMID: 28785084 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Ruetz et al. (2017), Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming Cell Stem Cell, 0(0).
PMID: 29174331 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Harper et al. (2017), TRAIL attenuates RANKL-mediated osteoblastic signalling in vascular cell mono-culture and co-culture models PLoS ONE, 12(11):e0188192.
PMID: 29145460 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKF Cogger et al. (2017), Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun, 8(1):331.
PMID: 28835709 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayH Isshiki et al. (2017), Establishment of a refined culture method for rat colon organoids Biochem. Biophys. Res. Commun., 0(0).
PMID: 28559141 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKW McCracken et al. (2017), Wnt/?-catenin promotes gastric fundus specification in mice and humans Nature, 0(0).
PMID: 28052057 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Bernhardt et al. (2017), Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response Stem Cell Reports, 0(0).
PMID: 28392221 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Yuan et al. (2017), A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model PLoS ONE, 12(4):e0174074.
PMID: 28441409 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Kilpinen et al. (2017), Common genetic variation drives molecular heterogeneity in human iPSCs Nature, 546(7658):370-375.
PMID: 28489815 -
Species: Human
Sample Types: Whole Cells
Applications: DifferentiationC Barry et al. (2017), Species-specific developmental timing is maintained by pluripotent stem cells ex utero Dev. Biol., 423(2):101-110.
PMID: 28179190 -
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay(2016), Growth hormone is permissive for neoplastic colon growth Proc Natl Acad Sci USA, 0(0).
PMID: 27226307 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJun Tao (2016), BMP4/Id2 signaling pathway is a novel therapeutic target for late outgrowth endothelial progenitor cell-mediated endothelial injury repair Int. J. Cardiol., 228(0):796-804.
PMID: 27888757 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Altered neuronal network and rescue in a human MECP2 duplication model Mol. Psychiatry, 21(2):178-88.
PMID: 26347316 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 27911769 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWarren C Plaisted (2016), Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis PLoS ONE, 11(6):e0157620.
PMID: 27310015 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLeslie J et al. (2015), Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function. Infect Immun, 83(1):138-45.
PMID: 25312952 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCebola I et al. (2015), TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. Nat Cell Biol, 17(5):615-26.
PMID: 25915126 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPezzolla D et al. (2015), Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells. PLoS ONE, 10(3):e0119904.
PMID: 25774684 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDye et al. (2015), In vitro generation of human pluripotent stem cell derived lung organoids. Elife, 4(0).
PMID: 25803487 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuang S et al. (2015), The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc, 10(3):413-25.
PMID: 25654758 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHernanda P et al. (2015), SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma. Oncogene, 34(39):5055-68.
PMID: 25531314 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAll A et al. (2015), Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. PLoS ONE, 10(1):e0116933.
PMID: 25635918 -
Species: Chicken
Sample Types: Whole Organism
Applications: In VivoHu D et al. (2015), A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face. Development, 142(3):567-74.
PMID: 25605783 -
Species: Chicken
Sample Types: Whole Tissue
Applications: BioassayThiede B et al. (2014), Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea. Nat Commun, 5(0):3840.
PMID: 24845860 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWattanapanitch M et al. (2014), Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages. PLoS ONE, 9(9):e106952.
PMID: 25207966 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCechin S et al. (2014), Influence of in vitro and in vivo oxygen modulation on beta cell differentiation from human embryonic stem cells. Stem Cells Transl Med, 3(3):277-89.
PMID: 24375542 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBurnight E et al. (2014), CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Gene Ther, 21(7):662-72.
PMID: 24807808 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHe Q et al. (2014), Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. Mol Biol Cell, 25(11):1715-29.
PMID: 24694597 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee et al. (2014), Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells. Sci Rep, 4(0):6319.
PMID: 25204726 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPereira et al. (2014), Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain. Sci Rep, 4(0):6330.
PMID: 25208484 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBayin et al. (2014), Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells. PLoS ONE, 9(12):e116114.
PMID: 25541984 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWeedon M et al. (2014), Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Nat Genet, 46(1):61-4.
PMID: 24212882 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDunworth et al. (2014), Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos. Circ Res, 114(1):56-66.
PMID: 24122719 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakeuchi et al. (2014), Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. Sci Rep, 4(0):4488.
PMID: 24671046 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayMann Z et al. (2014), A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun, 5(0):3839.
PMID: 24845721 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRonaghi et al. (2014), Inner ear hair cell-like cells from human embryonic stem cells. Stem Cells Dev, 23(11):1275-84.
PMID: 24512547 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLin P et al. (2014), A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells. Stem Cells Dev, 23(4):372-9.
PMID: 24083371 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLam A et al. (2014), Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J Am Soc Nephrol, 25(6):1211-25.
PMID: 24357672 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCai et al. (2014), Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells. Stem Cells Transl Med, 3(4):489-99.
PMID: 24493854 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRobson N et al. (2014), Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling. Cancer Res, 74(18):5019-31.
PMID: 25038228 -
Species: Mouse
Sample Types: Whole Organism
Applications: In VivoZhang Y et al. (2014), Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice. Arterioscler Thromb Vasc Biol, 34(1):152-9.
PMID: 24202302 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPethe et al. (2014), Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro. BMC Cell Biol, 15(0):18.
PMID: 24885493 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLippmann E et al. (2014), Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells, 32(4):1032-42.
PMID: 24357014 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFarmer et al. (2013), Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation. PLoS ONE, 8(3):e58813.
PMID: 23505563 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHannan et al. (2013), Generation of multipotent foregut stem cells from human pluripotent stem cells. Stem Cell Reports, 1(4):293-306.
PMID: 24319665 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTucker et al. (2013), Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. Elife, 2(0):e00824.
PMID: 23991284 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRezania A et al. (2013), Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells, 31(11):2432-42.
PMID: 23897760 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMaroof A et al. (2013), Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell, 12(5):559-72.
PMID: 23642365 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTalavera-Adame et al. (2013), Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev, 22(24):3252-60.
PMID: 23924071 -
Brafman D et al. (2013), Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death Differ, 20(3):369-81.
PMID: 23154389 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBuchholz et al. (2013), Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Transl Med, 2(5):384-93.
PMID: 23599499 -
Species: Xenopus
Sample Types: Whole Tissue
Applications: BioassaySwapna et al. (2012), Interplay between electrical activity and bone morphogenetic protein signaling regulates spinal neuron differentiation. Proc Natl Acad Sci U S A, 109(40):16336-41.
PMID: 22991474 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLi Q et al. (2012), Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene. J Biol Chem, 287(34):29088-100.
PMID: 22761414 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMaegdefrau U et al. (2011), Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma. Lab. Invest., 91(11):1615-23.
PMID: 21863061 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySpence JR et al. (2011), Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature, 470(7332):105-9.
PMID: 21151107 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKlim JR et al. (2010), A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat. Methods, 7(12):989-94.
PMID: 21076418 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJiang J et al. (0), Translating dosage compensation to trisomy 21. Natur500(7462):296-300.
PMID: 23863942 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKumar Gupta A et al. (0), Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids. Commun Bio3(1):231.
PMID: 32393756
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Customer Reviews for Recombinant Human Noggin Protein (8)
Customer Images
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 09/26/2021Used for iPSC differentiation into intestinal organoids at a concentration of 100ng/mL
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Application: Cell CultureVerified Customer | Posted 01/02/2021
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Application: CellProlifReason for Rating: Cells grew well.Verified Customer | Posted 12/28/2020
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 04/05/2019
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Application: Cell CultureVerified Customer | Posted 12/22/2017combination of a low dose of Noggin and the bone morphogenetic protein
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Verified Customer | Posted 04/25/2017
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Application: Neural differentiation of iPSCs. Image is Nestin(Green), Sox1 (red) staining.Verified Customer | Posted 01/04/2017
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Verified Customer | Posted 10/26/2015Noggin (100 ng/ml) was added into DMEM/F12 (plus B27 and N2) medium to promote neurogenesis of human-induced pluripotent stem cells.
There are no reviews that match your criteria.
FAQs for Recombinant Human Noggin Protein
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What is the half life of Recombinant Human Noggin Protein (Catalog # 6057-NG) in vitro?
Recombinant Human Noggin Protein (Catalog # 6057-NG) is evaluated for bioactivity by its ability to inhibit BMP-4-induced alkaline phosphatase production in mouse chondrogenic cells in vitro. We have not evaluated the half-life of 6057-NG. The half-life of a specific protein will depend on experimental conditions, including the cell number, density, and media content. It is up to the end-users to determine the appropriate concentration and timing when adding 6057-NG to individual experiments. For techniques and methodologies, we recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.
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Has Recombinant Human Noggin Protein (Catalog # 6057-NG or 6057-NG/CF) been evaluated in vivo?
Recombinant Human Noggin Protein (Catalog # 6057-NG) is evaluated for bioactivity by its ability to inhibit BMP-4-induced alkaline phosphatase production in mouse chondrogenic cells in vitro. We have not evaluated this protein for activity in vivo, but we are aware of publications citing use of the protein this type of experimentation. We recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.