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Key Product Details
Source: | NS0 |
Accession #: | Q53XC5 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations (368)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human BMP-4 Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: Cell CultureT Pan et al. (2020), Cabozantinib Reverses Renal Cell Carcinoma-Mediated Osteoblast Inhibition in Three-Dimensional Co-culture In Vitro and Reduces Bone Osteolysis In Vivo Mol. Cancer Ther., 0(0):.
PMID: 32220969 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureT Kroon et al. (2020), PPAR&gamma and PPAR&alpha synergize to induce robust browning of white fat in�vivo Mol Metab, 36(0):100964.
PMID: 32248079 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureH Liang et al. (2020), TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes Stem Cell Res Ther, 11(1):196.
PMID: 32448362 -
Species: Mouse
Applications: BioassayK Takahashi et al. (2020), Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells Cell Rep, 31(9):107715.
PMID: 32492424 -
Species: Human
Applications: BioassayM Nafria et al. (2020), Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells Cell Rep, 31(8):107691.
PMID: 32460028 -
Species: Human
Sample Types: cell culture
K Takeishi et al. (2020), Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells Cell Rep, 31(9):107711.
PMID: 32492423 -
Species: Human
Applications: BioassayM Martin-Fer et al. (2020), Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions Cell Rep, 31(6):107633.
PMID: 32402279 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Matsumoto et al. (2020), Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells J. Clin. Invest., 130(2):641-654.
PMID: 31845906 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Giacomelli et al. (2020), Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease Cell Stem Cell, 26(6):862-879.e11.
PMID: 32459996 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayA Krouwels et al. (2020), Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration Int J Mol Sci, 21(8):.
PMID: 32295299 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureM Grosch et al. (2020), Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation BMC Biol., 18(1):42.
PMID: 32321486 -
Species: Human
Applications: Cell CultureJ Wesely et al. (2020), Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells Cell Rep, 31(9):107688.
PMID: 32492433 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Yan et al. (2020), Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming Cell Rep, 32(1):107870.
PMID: 32640235 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Yamashiro et al. (2020), Generation of human oogonia from induced pluripotent stem cells in culture Nat Protoc, 15(4):1560-1583.
PMID: 32231324 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAS Ibrahim et al. (2020), Bone Morphogenetic Protein (BMP)4 But Not BMP2 Disrupts the Barrier Integrity of Retinal Pigment Epithelia and Induces Their Migration: A Potential Role in Neovascular Age-Related Macular Degeneration J Clin Med, 9(7):.
PMID: 32707711 -
Species: Human
Sample Types: cell culture
Applications: Cell CultureNJ Hogrebe et al. (2020), Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells Nat. Biotechnol., 0(0):.
PMID: 32094658 -
Species: Human
Sample Types: Cells
Applications: Cell CultureY Wang et al. (2020), HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells Nat. Immunol., 21(3):274-286.
PMID: 32066947 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Montel-Hag et al. (2019), Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells Cell Stem Cell, 0(0):.
PMID: 30661959 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureC Song et al. (2019), Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Stem Cell Reports, 0(0):.
PMID: 31353224 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Nasri et al. (2019), CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients Haematologica, 0(0):.
PMID: 31248972 -
Species: Human
Sample Types: Organoid
Applications: BioassayJM Segal et al. (2019), Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors Nat Commun, 10(1):3350.
PMID: 31350390 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Yoshimatsu et al. (2019), A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology PLoS ONE, 14(8):e0221164.
PMID: 31454364 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQ Mei et al. (2019), Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation Nat Commun, 10(1):4416.
PMID: 31562321 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Inoue et al. (2019), Autonomous trisomic rescue of Down syndrome cells Lab. Invest., 0(0):.
PMID: 30760866 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Yan et al. (2019), Cell population balance of cardiovascular spheroids derived from human induced pluripotent stem cells Sci Rep, 9(1):1295.
PMID: 30718597 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Ito et al. (2019), Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application Sci Rep, 9(1):1881.
PMID: 30760836 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zheng et al. (2019), Controlled modelling of human epiblast and amnion development using stem cells Nature, 573(7774):421-425.
PMID: 31511693 -
Species: Human
Sample Types: Whole Cells
Applications: Tissue CultureR Sachdeva et al. (2019), BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma Sci Rep, 9(1):14569.
PMID: 31602000 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Liang et al. (2019), Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells Stem Cells, 0(0):.
PMID: 31648393 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureW Song et al. (2019), Engineering transferrable microvascular meshes for subcutaneous islet transplantation Nat Commun, 10(1):4602.
PMID: 31601796 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayS Fujisawa et al. (2019), Orexin A modulates prolactin production by regulating BMP-4 activity in rat pituitary lactotorope cells Peptides, 0(0):.
PMID: 30721716 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHJ Bai et al. (2019), SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes Stem Cells, 0(0):.
PMID: 31348575 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Barber et al. (2019), Derivation of enteric neuron lineages from human pluripotent stem cells Nat Protoc, 14(4):1261-1279.
PMID: 30911172 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureS Pecha et al. (2019), Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model Sci Rep, 9(1):9831.
PMID: 31285568 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTR Broda et al. (2019), Generation of human antral and fundic gastric organoids from pluripotent stem cells Nat Protoc, 14(1):28-50.
PMID: 30470820 -
Species: Chicken
Sample Types: Tissue Explants
Applications: BioassayWKW Ho et al. (2019), Feather arrays are patterned by interacting signalling and cell density waves PLoS Biol., 17(2):e3000132.
PMID: 30789897 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Xu et al. (2019), Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility Cell Stem Cell, 0(0):.
PMID: 30853558 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Okada et al. (2019), Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia Sci Rep, 9(1):4695.
PMID: 30886174 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Yan et al. (2019), FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration Cell Stem Cell, 0(0):.
PMID: 30661960 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Toba et al. (2019), FGF signal is not required for hepatoblast differentiation of human iPS cells Sci Rep, 9(1):3713.
PMID: 30842525 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Grajcarek et al. (2019), Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations Nat Commun, 10(1):4856.
PMID: 31649251 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Hoshino et al. (2019), Synchrony and asynchrony between an epigenetic clock and developmental timing Sci Rep, 9(1):3770.
PMID: 30842553 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAM Blázquez-M et al. (2019), Noggin depletion in adipocytes promotes obesity in mice Mol Metab, 0(0):.
PMID: 31027994 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAD Senft et al. (2019), Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse Nat Commun, 10(1):1089.
PMID: 30842446 -
Species: Human
Sample Types: Tissue Explants
Applications: BioassayMJ Harms et al. (2019), Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes Cell Rep, 27(1):213-225.e5.
PMID: 30943403 -
Species: Human
Sample Types: cell culture
Applications: DifferentiationB Mair et al. (2019), Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies Cell Rep, 27(2):599-615.e12.
PMID: 30970261 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Colunga et al. (2019), Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair Cell Rep, 26(10):2566-2579.e10.
PMID: 30840882 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Li et al. (2019), TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment Cell Stem Cell, 0(0):.
PMID: 30686763 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Veschi et al. (2019), Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant Oncogene, 0(0):.
PMID: 31591478 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Kuwahara et al. (2019), Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue Sci Rep, 9(1):18936.
PMID: 31831759 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Stubb et al. (2019), Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells Nat Commun, 10(1):4756.
PMID: 31628312 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Sahabian et al. (2019), Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential Cells, 8(12):.
PMID: 31817235 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySTJ Bradford et al. (2019), High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds J. Biol. Chem., 0(0):.
PMID: 30602563 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Jacob et al. (2019), Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells Nat Protoc, 0(0):.
PMID: 31732721 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureD Seo et al. (2019), The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway EBioMedicine, 49(0):55-71.
PMID: 31685442 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureGL Tiemeier et al. (2019), Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation Stem Cell Reports, 13(5):803-816.
PMID: 31680061 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureZ Li et al. (2019), Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells Stem Cell Res Ther, 10(1):324.
PMID: 31730021 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureD Chen et al. (2019), Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors Cell Rep, 29(13):4568-4582.e5.
PMID: 31875561 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRMJ Genga et al. (2019), Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development Cell Rep, 27(3):708-718.e10.
PMID: 30995470 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Roudnicky et al. (2019), Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype Int J Mol Sci, 20(24):.
PMID: 31835296 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Sattler et al. (2019), Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes Sci Rep, 9(1):5651.
PMID: 30948775 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Nagel et al. (2019), NKL homeobox gene activities in normal and malignant myeloid cells PLoS ONE, 14(12):e0226212.
PMID: 31825998 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Matsuura et al. (2019), Adequate taylor couette flow-mediated shear stress is useful for dissociating human iPS cell-derived cell aggregates Regen Ther, 12(0):6-13.
PMID: 31890761 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Ali et al. (2019), Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies Sci Rep, 9(1):18552.
PMID: 31811247 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAD Senft et al. (2018), Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming Cell Rep, 24(8):1977-1985.e7.
PMID: 30134160 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Yoney et al. (2018), WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids Elife, 7(0):.
PMID: 30311909 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Pursani et al. (2018), Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage Stem Cell Res Ther, 9(1):97.
PMID: 29631608 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Li et al. (2018), Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages Cell Transplant, 0(0):9636897187803.
PMID: 29895168 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Buskin et al. (2018), Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa Nat Commun, 9(1):4234.
PMID: 30315276 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Devito et al. (2018), Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A Stem Cell Res, 31(0):122-126.
PMID: 30075366 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Kirino et al. (2018), Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition Sci Rep, 8(1):12865.
PMID: 30150715 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Magro-Lope et al. (2018), Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids Stem Cell Res Ther, 9(1):186.
PMID: 29996941 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZ Xu et al. (2018), Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes Stem Cell Res Ther, 9(1):211.
PMID: 30092828 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJJ Gell et al. (2018), PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation Stem Cell Res, 27(0):46-56.
PMID: 29324254 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Di Baldass et al. (2018), Cardiomyocytes Derived from Human CardiopoieticAmniotic Fluids Sci Rep, 8(1):12028.
PMID: 30104705 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Delsing et al. (2018), Barrier properties and transcriptome expression in human iPSC-derived models of the blood-brain barrier Stem Cells, 0(0):.
PMID: 30171748 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Koefoed et al. (2018), The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development Sci Rep, 8(1):9542.
PMID: 29934521 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2018), 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling Cell Stem Cell, 0(0):.
PMID: 30244870 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Chen et al. (2018), The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation Cell Rep, 25(13):3591-3602.e5.
PMID: 30590035 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Tengroth et al. (2018), Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps Sci Rep, 8(1):1561.
PMID: 29367682 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Frank et al. (2018), yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs Cell Stem Cell, 0(0):.
PMID: 30554961 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySS Adkar et al. (2018), Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing Stem Cells, 0(0):.
PMID: 30378731 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCC Weng et al. (2018), Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis Oncogene, 0(0):.
PMID: 30467381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJM Pattison et al. (2018), Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment Nat. Genet., 0(0):.
PMID: 30397335 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJGW Smith et al. (2018), Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits Stem Cell Reports, 0(0):.
PMID: 30392975 -
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: BioassayY Kang et al. (2018), Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys Cell Rep, 25(9):2563-2576.e9.
PMID: 30485820 -
Species: Chicken
Sample Types: Embryo
Applications: BioassayP Ray et al. (2018), Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping Proc. Natl. Acad. Sci. U.S.A., 0(0):.
PMID: 30459275 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Guo et al. (2018), A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis Cell Stem Cell, 0(0):.
PMID: 29754779 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYC Chen et al. (2018), ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA Cell Death Dis, 9(4):437.
PMID: 29740017 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRA Sierra et al. (2018), TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency Development, 0(0):.
PMID: 29361574 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Okamoto et al. (2018), Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B Cell Transplant, 27(2):299-309.
PMID: 29637813 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJS Esser et al. (2018), Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial-venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells FEBS J., 0(0):.
PMID: 29473997 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Jun et al. (2018), An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling Nat. Med., 0(0):.
PMID: 29785025 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Jin et al. (2018), Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery PLoS ONE, 13(3):e0194895.
PMID: 29579079 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Yachie-Kin et al. (2018), Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions Mol. Syst. Biol., 14(1):e7952.
PMID: 29378814 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEJ Ostrin et al. (2018), Beta-Catenin maintains lung epithelial progenitors after lung specification Development, 0(0):.
PMID: 29440304 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Kondrashov et al. (2018), Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells Stem Cells Dev., 0(0):.
PMID: 29402189 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Wang et al. (2018), Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype Int J Mol Sci, 19(2):.
PMID: 29419805 -
Species: Human
Sample Types: Whole Cells
Applications: DifferentiationT Yamashita et al. (2018), Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29409945 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Long et al. (2018), Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing Sci Adv, 4(1):eaap9004.
PMID: 29404407 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayG Yücel et al. (2017), Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes Sci Rep, 7(1):2935.
PMID: 28592841 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Harding et al. (2017), Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways Stem Cells, 0(0):.
PMID: 28248004 -
Species: Xenopus
Sample Types: In Vivo
Applications: In VivoP Scerbo et al. (2017), Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2 Elife, 6(0):.
PMID: 28654420 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Raja et al. (2017), Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells Oncogene, 0(0):.
PMID: 28459464 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Koike et al. (2017), Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism Development, 0(0):.
PMID: 28219950 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2017), Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells Nat Protoc, 12(1):15-31.
PMID: 27906170 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMT Uemura et al. (2017), Pericyte-derived Bone Morphogenetic Protein 4 Underlies White Matter Damage after Chronic Hypoperfusion Brain Pathol., 0(0):.
PMID: 28470822 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNG Kooreman et al. (2017), Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics Cell Rep, 20(8):1978-1990.
PMID: 28834758 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Kajiwara et al. (2017), Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells Stem Cell Reports, 8(6):1701-1713.
PMID: 28591652 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDW Hammers et al. (2017), Supraphysiological levels of GDF11 induce striated muscle atrophy EMBO Mol Med, 0(0):.
PMID: 28270449 -
Species: Human
Sample Types: Recombinant Protein
Applications: BioassayC Sallon et al. (2017), Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells J. Biol. Chem., 0(0):.
PMID: 28747434 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Giacomelli et al. (2017), Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells Development, 144(6):1008-1017.
PMID: 28279973 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Sakurai et al. (2017), Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection Sci Rep, 7(0):45698.
PMID: 28374759 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayBA Boswell et al. (2017), Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract Mol. Biol. Cell, 0(0):.
PMID: 28209733 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBW Ellis et al. (2017), Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine Biomicrofluidics, 11(2):024105.
PMID: 28396709 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Mitani et al. (2017), Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling Mol. Ther., 25(6):1420-1433.
PMID: 28462819 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayK Ogura-Ochi et al. (2017), Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells Peptides, 0(0):.
PMID: 28627372 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJW Park et al. (2017), Recapitulating and Correcting Marfan Syndrome in a Cellular Model Int. J. Biol. Sci., 13(5):588-603.
PMID: 28539832 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Hawkins et al. (2017), Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells J. Clin. Invest., 127(6):2277-2294.
PMID: 28463226 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Aberdam et al. (2017), Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing PLoS ONE, 12(6):e0179913.
PMID: 28640863 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKW McCracken et al. (2017), Wnt/?-catenin promotes gastric fundus specification in mice and humans Nature, 0(0):.
PMID: 28052057 -
Applications: Western BlotI Wagner et al. (2017), Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration Dev. Cell, 40(6):608-617.e6.
PMID: 28350991 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Rahman et al. (2017), Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence Nat Commun, 8(0):15380.
PMID: 28541275 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Campbell et al. (2017), Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration Sci Rep, 7(1):3978.
PMID: 28638124 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Xing et al. (2017), In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening Sci Rep, 7(1):8491.
PMID: 28819231 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Yucer et al. (2017), Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium Sci Rep, 7(1):10741.
PMID: 28878359 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Choudhury et al. (2017), Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity Sci Rep, 7(0):41238.
PMID: 28120901 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHK Voges et al. (2017), Development of a human cardiac organoid injury model reveals innate regenerative potential Development, 0(0):.
PMID: 28174241 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Chattopadh et al. (2017), Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway Biofactors, 0(0):.
PMID: 28186649 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Tiburcy et al. (2017), Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair Circulation, 135(19):1832-1847.
PMID: 28167635 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKM Tsang et al. (2017), Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1? Stem Cell Reports, 0(0):.
PMID: 28781077 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Jung et al. (2017), In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells Nat Commun, 8(0):15680.
PMID: 28604658 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAG Kotini et al. (2017), Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia Cell Stem Cell, 0(0):.
PMID: 28215825 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKB McCauley et al. (2017), Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling Cell Stem Cell, 0(0):.
PMID: 28366587 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAG Freire et al. (2017), Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate Stem Cell Reports, 0(0):.
PMID: 28648899 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJH Lee et al. (2017), Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations Cell Stem Cell, 21(2):179-194.e4.
PMID: 28777944 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayK Breckwoldt et al. (2017), Differentiation of cardiomyocytes and generation of human engineered heart tissue Nat Protoc, 12(6):1177-1197.
PMID: 28492526 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Kumar et al. (2017), Induction of senescence in primary glioblastoma cells by serum and TGF? Sci Rep, 7(1):2156.
PMID: 28526854 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Low et al. (2017), Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System Stem Cell Reports, 0(0):.
PMID: 28457888 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Yamamizu et al. (2017), In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling Stem Cell Reports, 0(0):.
PMID: 28238797 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Krendl et al. (2017), GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency Proc. Natl. Acad. Sci. U.S.A., 0(0):.
PMID: 29078328 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNJ Palpant et al. (2017), Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis Cell Rep, 20(7):1597-1608.
PMID: 28813672 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Shao et al. (2017), A pluripotent stem cell-based model for post-implantation human amniotic sac development Nat Commun, 8(1):208.
PMID: 28785084 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJH Lee et al. (2017), Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency Cell Rep, 19(1):20-35.
PMID: 28380358 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Kojima et al. (2017), Efficient production of trophoblast lineage cells from human induced pluripotent stem cells Lab. Invest, 0(0):.
PMID: 28287635 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLA Ahrens et al. (2017), Gelatin device for the delivery of growth factors involved in endochondral ossification PLoS ONE, 12(4):e0175095.
PMID: 28380024 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJP Matson et al. (2017), Rapid DNA replication origin licensing protects stem cell pluripotency Elife, 6(0):.
PMID: 29148972 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Sampazioti et al. (2017), Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells Nat Protoc, 12(4):814-827.
PMID: 28333915 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAA Mody et al. (2017), Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-?2 in Human TM Cells Invest. Ophthalmol. Vis. Sci, 58(2):849-859.
PMID: 28159972 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Jeziorowsk et al. (2017), Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols Int J Mol Sci, 18(6):.
PMID: 28587156 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Ampuja et al. (2017), Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer BMC Genomics, 18(1):68.
PMID: 28077088 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Tachida et al. (2017), Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells Biol Open, 6(3):370-380.
PMID: 28298363 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Taguchi et al. (2017), Higher-Order Kidney Organogenesis from Pluripotent Stem Cells Cell Stem Cell, 0(0):.
PMID: 29129523 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayR McLennan et al. (2017), DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion J. Cell Biol., 216(10):3339-3354.
PMID: 28811280 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Warrier et al. (2017), Direct comparison of distinct naive pluripotent states in human embryonic stem cells Nat Commun, 8(0):15055.
PMID: 28429706 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Li et al. (2017), Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium Stem Cell Reports, 0(0):.
PMID: 29107590 -
Species: Zebrafish
Sample Types: Whole Tissue
Applications: BioassayOH Ocaña et al. (2017), A right-handed signalling pathway drives heart looping in vertebrates Nature, 549(7670):86-90.
PMID: 28880281 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLK Bollum et al. (2017), BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5 PLoS ONE, 12(5):e0177188.
PMID: 28489883 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage Stem Cells, 0(0):.
PMID: 27571517 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Medial HOXA genes demarcate haematopoietic stem cell fate during human development Nat Cell Biol, 0(0):.
PMID: 27183470 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMariko Horii (2016), Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease Proc Natl Acad Sci USA, 0(0):.
PMID: 27325764 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuang-Tian Yang (2016), Coupling switch of P2Y-IP3 receptors mediates differential Ca(2+) signaling in human embryonic stem cells and derived cardiovascular progenitor cells Purinergic Signal., 12(3):465-78.
PMID: 27098757 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker Nat. Biotechnol, 0(0):.
PMID: 27941801 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Kadota et al. (2016), In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts Stem Cell Reports, 0(0):.
PMID: 28065644 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves EBioMedicine, 10(0):282-90.
PMID: 27394642 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Zeltner et al. (2016), Capturing the biology of disease severity in a PSC-based model of familial dysautonomia Nat. Med., 22(12):1421-1427.
PMID: 27841875 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRobert Thomas (2016), Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation Biotechnol. Prog., 32(1):215-23.
PMID: 26560993 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9) PLoS ONE, 11(11):e0166382.
PMID: 27875556 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation Stem Cell Res, 17(2):222-227.
PMID: 27591478 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayG B de Souza (2016), Bovine ovarian stem cells differentiate into germ cells and oocyte-like structures after culture in vitro Reprod. Domest. Anim, 0(0):.
PMID: 27925309 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes Stem Cell Reports, 0(0):.
PMID: 27569062 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients Elife, 5(0):.
PMID: 27458797 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway Cell Biosci, 6(1):50.
PMID: 27583127 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChristine Kestens et al. (2016), BMP4 Signaling Is Able to Induce an Epithelial-Mesenchymal Transition-Like Phenotype in Barrett's Esophagus and Esophageal Adenocarcinoma through Induction of SNAIL2. PLoS ONE, 0(0):1932-6203.
PMID: 27191723 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHermanson D et al. (2016), Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer. Stem Cells, 34(1):93-101.
PMID: 26503833 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication PLoS ONE, 11(12):e0168334.
PMID: 27977771 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells EMBO Mol Med, 0(0):.
PMID: 27470144 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIA Song et al. (2016), The involvement of protein kinase C-? in isoflurane induced preconditioning of human embryonic stem cell--derived Nkx2.5(+) cardiac progenitor cells BMC Anesthesiol, 16(0):13.
PMID: 26897636 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Five colour variants of bright luminescent protein for real-time multicolour bioimaging Nat Commun, 7(0):13718.
PMID: 27966527 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOlivier Abbo (2016), Comparison between pediatric and adult adipose mesenchymal stromal cells Cytotherapy, 0(0):.
PMID: 28040462 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIrene De Almeida (2016), Calreticulin is a secreted BMP antagonist, expressed in Hensen's node during neural induction Dev. Biol, 0(0):.
PMID: 27919666 -
Sample Types: Protein
Applications: BioassayArnold Junior Tatsinkam (2016), The Binding of the Bone Morphogenetic Protein Antagonist Gremlin to Kidney Heparan Sulfate: Such Binding is not Essential for BMP Antagonism Int. J. Biochem. Cell Biol, 0(0):.
PMID: 27979781 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes Stem Cells Transl Med, 0(0):.
PMID: 27591141 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells Sci Rep, 6(0):31063.
PMID: 27507707 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells Nat Commun, 7(0):13602.
PMID: 27934856 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuggal G et al. (2015), Alternative Routes to Induce Naive Pluripotency in Human Embryonic Stem Cells. Stem Cells, 33(9):2686-98.
PMID: 26108678 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim J et al. (2015), BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells. Mol Cancer, 14(1):173.
PMID: 26395571 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKim M et al. (2015), Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. PLoS ONE, 10(2):e0118670.
PMID: 25706534 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGerbin K et al. (2015), Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts. PLoS ONE, 10(7):e0131446.
PMID: 26161513 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIyer D et al. (2015), Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells. Development, 142(8):1528-41.
PMID: 25813541 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoGottle P et al. (2015), Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci, 35(3):906-19.
PMID: 25609610 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWong S et al. (2015), Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion. Cancer Res, 75(6):1113-22.
PMID: 25634210 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySong B et al. (2015), Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system. Stem Cells Dev, 24(9):1053-65.
PMID: 25517294 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee J et al. (2015), Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells, 33(4):1142-52.
PMID: 25639500 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMuller P et al. (2015), Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines. PLoS ONE, 10(7):e0131467.
PMID: 26173116 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTadeu A et al. (2015), Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. PLoS ONE, 10(4):e0122493.
PMID: 25849374 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTate C et al. (2015), A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology. PLoS ONE, 10(4):e0125697.
PMID: 25919028 -
Kitajima K et al. (2015), GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells. Exp Hematol, 44(1):68-74.e10.
PMID: 26477526 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMaury Y et al. (2015), Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes. Nat Biotechnol, 33(1):89-96.
PMID: 25383599 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTsankov et al. (2015), Transcription factor binding dynamics during human ES cell differentiation. Nature, 518(7539):344-9.
PMID: 25693565 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySugawa F et al. (2015), Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile. EMBO J, 34(8):1009-24.
PMID: 25750208 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWu J et al. (2015), Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells. Stem Cells Dev, 24(7):892-903.
PMID: 25405279 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCraft A et al. (2015), Generation of articular chondrocytes from human pluripotent stem cells. Nat Biotechnol, 33(6):638-45.
PMID: 25961409 -
Species: Chicken
Sample Types: Whole Organism
Applications: In VivoHu D et al. (2015), A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face. Development, 142(3):567-74.
PMID: 25605783 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWong et al. (2015), Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nat Protoc, 10(3):363-81.
PMID: 25654755 -
Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
Sample Types: Whole Cells
Applications: BioassayGori J et al. (2015), Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells. J Clin Invest, 125(3):1243-54.
PMID: 25664855 -
Species: Chicken
Sample Types: Whole Tissue
Applications: BioassayRay P et al. (2015), Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling. PLoS ONE, 10(8):e0134702.
PMID: 26237312 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNio-Kobayashi J et al. (2015), Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum. Endocrinology, 156(4):1494-503.
PMID: 25635621 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuang S et al. (2015), The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc, 10(3):413-25.
PMID: 25654758 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMajumder A et al. (2015), Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem, 290(21):13053-63.
PMID: 25847244 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYang Y et al. (2015), Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure. Proc Natl Acad Sci U S A, 112(18):E2337-46.
PMID: 25870291 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFang F et al. (2014), The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function. J Cell Sci, 127(0):1428-40.
PMID: 24463812 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayLorda-Diez C et al. (2014), Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro. J Bone Miner Res, 29(3):735-48.
PMID: 24038612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRonaghi et al. (2014), Inner ear hair cell-like cells from human embryonic stem cells. Stem Cells Dev, 23(11):1275-84.
PMID: 24512547 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMahadevan et al. (2014), NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation. Hum Mol Genet, 23(3):706-16.
PMID: 24105472 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakebe et al. (2014), Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant. Nat Protoc, 9(2):396-409.
PMID: 24457331 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuang et al. (2014), Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol, 32(1):84-91.
PMID: 24291815 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee et al. (2014), Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells. Sci Rep, 4(0):6319.
PMID: 25204726 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJosowitz et al. (2014), Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression. PLoS ONE, 9(7):e101316.
PMID: 25010565 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayMann Z et al. (2014), A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun, 5(0):3839.
PMID: 24845721 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWatanabe et al. (2014), HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin. PLoS ONE, 9(3):e90791.
PMID: 24651531 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakayama K et al. (2014), CCAAT/enhancer binding protein-mediated regulation of TGFbeta receptor 2 expression determines the hepatoblast fate decision. Development, 141(1):91-100.
PMID: 24284203 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCulbert A et al. (2014), Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification. Stem Cells, 32(5):1289-300.
PMID: 24449086 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOlsen O et al. (2014), Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer J, 4(0):e196.
PMID: 24658374 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChang C et al. (2014), Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells. PLoS ONE, 9(5):e97335.
PMID: 24828440 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakahashi K et al. (2014), Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm. Nat Commun, 5(0):3678.
PMID: 24759836 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTurnbull I et al. (2014), Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J, 28(2):644-54.
PMID: 24174427 -
Cao Y et al. (2014), BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity. Cancer Res, 74(18):5091-102.
PMID: 25224959 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLam A et al. (2014), Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J Am Soc Nephrol, 25(6):1211-25.
PMID: 24357672 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOhnuma et al. (2014), Enzyme-free passage of human pluripotent stem cells by controlling divalent cations. Sci Rep, 4(0):4646.
PMID: 24721898 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLuo J et al. (2014), Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo. Stem Cells Transl Med, 3(6):734-44.
PMID: 24736402 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTsuchida et al. (2014), BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors. Oncogene, 33(29):3803-11.
PMID: 24013228 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTolar J et al. (2014), Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol, 134(5):1246-54.
PMID: 24317394 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTodaro M et al. (2014), CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell, 14(3):342-56.
PMID: 24607406 -
Kim W et al. (2014), Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells, 32(6):1503-14.
PMID: 24677652 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYang et al. (2014), Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells. Nat Commun, 5(0):3071.
PMID: 24468981 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYamada et al. (2014), Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury. PLoS ONE, 9(2):e89135.
PMID: 24586548 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLim M et al. (2014), Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor. PLoS ONE, 9(9):e107712.
PMID: 25229469 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShelton M et al. (2014), Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells. Stem Cell Reports, 3(3):516-29.
PMID: 25241748 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFerrell et al. (2014), Functional assessment of hematopoietic niche cells derived from human embryonic stem cells. Stem Cells Dev, 23(12):1355-63.
PMID: 24517837 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTaguchi A et al. (2014), Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell, 14(1):53-67.
PMID: 24332837 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJakobsen R et al. (2014), Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE, 9(5):e96615.
PMID: 24816923 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayZhang Y et al. (2014), Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice. Arterioscler Thromb Vasc Biol, 34(1):152-9.
PMID: 24202302 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKondo T et al. (2014), Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice. Stem Cell Reports, 3(2):242-9.
PMID: 25254338 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJiang D et al. (2014), MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-beta1/SMAD5 signaling module. Blood, 123(1):86-93.
PMID: 24136167 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLaperrousaz B et al. (2014), Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression. Blood, 122(23):3767-77.
PMID: 24100446 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDominguez et al. (2014), Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies. Sci Rep, 4(0):6432.
PMID: 25242416 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMorishima et al. (2014), Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis. Haematologica, 99(1):19-27.
PMID: 23975175 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKobayashi et al. (2014), Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome. PLoS ONE, 9(7):e102796.
PMID: 25050861 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayAo et al. (2014), High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells. PLoS ONE, 9(6):e100417.
PMID: 24949734 -
Srikanth et al. (2014), BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells. Mol Cancer Res, 12(2):283-94.
PMID: 24269952 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLin et al. (2014), Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells. Stem Cell Reports, 2(2):189-204.
PMID: 24527393 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWile B et al. (2014), Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs. Nat Protoc, 9(10):2411-24.
PMID: 25232937 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPark et al. (2014), Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs. Proc Natl Acad Sci U S A, 111(25):9253-8.
PMID: 24927536 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXue et al. (2014), Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes. Am J Physiol Endocrinol Metab, 306(4):E363-72.
PMID: 24347060 -
Species: Equine
Sample Types: Whole Cells
Applications: BioassayCabrera-Sharp V et al. (2014), SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion. Endocrinology, 155(8):3054-64.
PMID: 24848867 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTalavera-Adame et al. (2013), Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev, 22(24):3252-60.
PMID: 23924071 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHannan et al. (2013), Production of hepatocyte-like cells from human pluripotent stem cells. Nat Protoc, 8(2):430-7.
PMID: 23370178 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayReinhardt P et al. (2013), Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS ONE, 8(3):e59252.
PMID: 23533608 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGoldman O et al. (2013), KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell, 12(6):748-60.
PMID: 23746980 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureGoyal et al. (2013), Generation of human induced pluripotent stem cells using epigenetic regulators reveals a germ cell-like identity in partially reprogrammed colonies. PLoS ONE, 8(12):e82838.
PMID: 24349377 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDoulatov S et al. (2013), Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell, 13(4):459-70.
PMID: 24094326 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayGlister C et al. (2013), Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production. Proc Natl Acad Sci U S A, 110(15):E1426-35.
PMID: 23530236 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNavarrete E et al. (2013), Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation, 128(11):S3-13.
PMID: 24030418 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHigurashi N et al. (2013), A human Dravet syndrome model from patient induced pluripotent stem cells. Mol Brain, 6(0):19.
PMID: 23639079 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKawabata K et al. (2013), TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20. Oncogene, 32(16):2096-106.
PMID: 22665052 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFujiwara et al. (2013), A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease. PLoS ONE, 8(9):e75568.
PMID: 24086573 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVrijens K et al. (2013), Identification of small molecule activators of BMP signaling. PLoS ONE, 8(3):e59045.
PMID: 23527084 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWhite M et al. (2013), Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells, 31(1):92-103.
PMID: 23079999 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayGu L et al. (2013), Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential. Lab Invest, 93(4):450-61.
PMID: 23439432 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChou H et al. (2013), BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro. PLoS ONE, 8(3):e58441.
PMID: 23472198 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakayama K et al. (2013), Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes. Stem Cell Reports, 1(4):322-35.
PMID: 24319667 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureKohler et al. (2013), Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. PLoS ONE, 8(12):e85549.
PMID: 24386480 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPick M et al. (2013), Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium. PLoS ONE, 8(2):e55530.
PMID: 23424635 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLiang et al. (2013), Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation, 127(16):1677-91.
PMID: 23519760 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuggal G et al. (2013), Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential. Stem Cells Dev, 22(23):3141-55.
PMID: 23829223 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDeschaseaux F et al. (2013), Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue. FASEB J, 27(8):2977-87.
PMID: 23592762 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang Y et al. (2013), Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell, 25(1):69-80.
PMID: 23541921 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee J et al. (2013), Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. Elife, 2(0):e00940.
PMID: 24252877 -
Species: Human
Sample Types: Recombinant Protein
Applications: Binding AssayKim M et al. (2012), Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion. PLoS ONE, 7(4):e35100.
PMID: 22514712 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012), Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. Gene Ther, 19(10):1035-40.
PMID: 22071967 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceWu et al. (2012), Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE, 7(9):e46307.
PMID: 23029472 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCheung C et al. (2012), Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility. Nat. Biotechnol., 30(2):165-73.
PMID: 22252507 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJoubin et al. (2012), The endothelial cell line bEnd.3 maintains human pluripotent stem cells. Stem Cells Dev, 21(12):2312-21.
PMID: 22224974 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayAad et al. (2012), The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol Reprod, 87(4):79.
PMID: 22811575 -
Species: Human
Sample Types: Cell Lysates
Applications: BioassayYao Y et al. (2012), Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood, 119(21):5037-47.
PMID: 22474252 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuse K et al. (2012), Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma. PLoS ONE, 7(10):e46117.
PMID: 23049692 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPereira P et al. (2012), Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion. Development, 139(18):3343-54.
PMID: 22912414 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWong RC et al. (2011), A novel role for an RNA polymerase III subunit POLR3G in regulating pluripotency in human embryonic stem cells. Stem Cells, 29(10):1517-27.
PMID: 21898682 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuse K et al. (2011), Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7. Eur. J. Immunol., 41(11):3135-45.
PMID: 21898381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRochira JA et al. (2011), A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-kappaB activation and apoptosis in P19 cells. PLoS ONE, 6(7):e20659.
PMID: 21789165 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDavis-Dusenbery BN et al. (2011), Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4. J. Biol. Chem., 286(32):28097-110.
PMID: 21673106 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceCastonguay R et al. (2011), Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 286(34):30034-46.
PMID: 21737454 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGeens M et al. (2011), Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells. J. Assist. Reprod. Genet., 0(0):.
PMID: 21318592 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhang Q et al. (2011), Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res., 21(4):579-87.
PMID: 21102549 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMaegdefrau U et al. (2011), Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma. Lab. Invest., 91(11):1615-23.
PMID: 21863061 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNiwa A et al. (2011), A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS ONE, 6(7):e22261.
PMID: 21818303 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTolar J et al. (2011), Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood, 117(3):839-47.
PMID: 21037085 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChng Z et al. (2010), SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells. Cell Stem Cell, 6(1):59-70.
PMID: 20074535 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureRoelandt P et al. (2010), Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS ONE, 5(8):e12101.
PMID: 20711405 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceMartino MM et al. (2010), The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J., 24(12):4711-21.
PMID: 20671107 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLanner F et al. (2010), Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. Stem Cells, 28(2):191-200.
PMID: 19937756 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRai D et al. (2010), Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc. Natl. Acad. Sci. U.S.A., 107(7):3111-6.
PMID: 20133617 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKlim JR et al. (2010), A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat. Methods, 7(12):989-94.
PMID: 21076418 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGrcevic D et al. (2010), Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes. Leuk. Res., 34(6):742-51.
PMID: 19926132 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStewart A et al. (2010), BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway. J. Cell. Physiol., 223(3):658-66.
PMID: 20143330 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayStevens KR et al. (2009), Scaffold-free human cardiac tissue patch created from embryonic stem cells. Tissue Eng Part A, 15(6):1211-22.
PMID: 19063661 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHerrera B et al. (2009), A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol., 10(0):20.
PMID: 19298647 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBernardo AS et al. (2009), Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem Cells, 27(2):341-51.
PMID: 19056911 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTanno T et al. (2009), Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood, 114(1):181-6.
PMID: 19414861 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKelly MA et al. (2009), Signaling hierarchy regulating human endothelial cell development. Arterioscler. Thromb. Vasc. Biol., 29(5):718-24.
PMID: 19213939 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySugiura K et al. (2009), Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells. Biol. Reprod., 81(5):833-41.
PMID: 19553596 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoSellers DL et al. (2009), Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury. J. Neurosci., 29(20):6722-33.
PMID: 19458241 -
Species: Xenopus
Sample Types: Whole Cells
Applications: BioassayLevine AJ et al. (2009), GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses. Dev. Biol., 325(1):43-8.
PMID: 18823971 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYe L et al. (2009), Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc. Natl. Acad. Sci. U.S.A., 106(24):9826-30.
PMID: 19482945 -
Species: Rabbit
Sample Types: In Vivo
Applications: In VivoAnderson BC et al. (2008), Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci., 49(1):221-9.
PMID: 18172096 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDesbordes SC et al. (2008), High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell, 2(6):602-12.
PMID: 18522853 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayElkabetz Y et al. (2008), Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev., 22(2):152-65.
PMID: 18198334 -
Species: Human
Sample Types: Cell Lysates
Applications: Binding AssayKane R et al. (2008), Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol. Vis., 14(0):1138-48.
PMID: 18587495 -
Species: Human
Sample Types: Recombinant Protein
Applications: Binding AssaySengle G et al. (2008), Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem., 283(20):13874-88.
PMID: 18339631 -
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: BioassaySaeki K et al. (2008), Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells. J. Cell. Physiol., 217(1):261-80.
PMID: 18551514 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWu Z et al. (2008), Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells. J. Biol. Chem., 283(36):24991-5002.
PMID: 18596037 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySun Y et al. (2008), Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Mol. Cell. Neurosci., 38(2):245-58.
PMID: 18450476 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayBoswell BA et al. (2008), Essential role of BMPs in FGF-induced secondary lens fiber differentiation. Dev. Biol., 324(2):202-12.
PMID: 18848538 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYang L et al. (2008), Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature, 453(7194):524-8.
PMID: 18432194 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySouthwood M et al. (2008), Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J. Pathol., 214(1):85-95.
PMID: 17992660 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJeanpierre S et al. (2008), BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood, 112(8):3154-63.
PMID: 18664625 -
Species: Chicken
Sample Types: Whole Tissue
Applications: BioassayBoswell BA et al. (2008), Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells. Mol. Biol. Cell, 19(6):2631-41.
PMID: 18400943 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTseng YH et al. (2008), New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature, 454(7207):1000-4.
PMID: 18719589 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChen G et al. (2008), Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell, 2(4):345-55.
PMID: 18397754 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayYao Y et al. (2008), High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2. Arterioscler. Thromb. Vasc. Biol., 28(12):2266-74.
PMID: 18948634 -
Sample Types: Whole Cells
Applications: BioassayZilberberg L et al. (2007), A rapid and sensitive bioassay to measure bone morphogenetic protein activity. BMC Cell Biol, 8(0):41.
PMID: 17880711 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLin L et al. (2007), Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood, 110(6):2182-9.
PMID: 17540841 -
Fuller ML et al. (2007), Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions. Ann. Neurol., 62(3):288-300.
PMID: 17696121 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStabile H et al. (2007), Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor. Blood, 109(5):1834-40.
PMID: 17077323 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakahashi K et al. (2007), Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131(5):861-72.
PMID: 18035408 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayKavanagh KD et al. (2007), Predicting evolutionary patterns of mammalian teeth from development. Nature, 449(7161):427-32.
PMID: 17898761 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTesar PJ et al. (2007), New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 448(7150):196-9.
PMID: 17597760 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStavridis MP et al. (2007), A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. Development, 134(16):2889-94.
PMID: 17660197 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayKnobloch J et al. (2007), Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway. FASEB J., 21(7):1410-21.
PMID: 17283219 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZode GS et al. (2007), Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells. Invest. Ophthalmol. Vis. Sci., 48(11):5058-67.
PMID: 17962458 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhang P et al. (2007), Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood, 111(4):1933-41.
PMID: 18042803 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRajesh</LastName><ForeNam D</Initial et al. (2007), Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 25(2):490-9.
PMID: 17284653 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassaySpicer LJ et al. (2006), Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells. J. Endocrinol., 189(2):329-39.
PMID: 16648300 -
Species: Primate - Callitrix jacchus (Common Marmoset)
Sample Types: Whole Cells
Applications: BioassayKurita R et al. (2006), Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells. Stem Cells, 24(9):2014-22.
PMID: 16728561 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLindsley RC et al. (2006), Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 133(19):3787-96.
PMID: 16943279 -
Species: Rat
Sample Types: Whole Tissue
Applications: BioassayMaeshima A et al. (2006), Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev. Biol., 295(2):473-85.
PMID: 16643884 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIkeya M et al. (2006), Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development, 133(22):4463-73.
PMID: 17035289 -
Species: Chicken
Sample Types: In Ovo
Applications: In OvoBonafede A et al. (2006), BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression. Dev. Biol., 299(2):330-44.
PMID: 17005177 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayZeng L et al. (2006), Multipotent adult progenitor cells from swine bone marrow. Stem Cells, 24(11):2355-66.
PMID: 16931778 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYao S et al. (2006), Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl. Acad. Sci. U.S.A., 103(18):6907-12.
PMID: 16632596 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKiyono M et al. (2006), Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis induced by BMP4. Oncogene, 25(54):7131-7.
PMID: 16732319 -
Species: Xenopus
Sample Types: In Vivo
Applications: In VivoHolzschuh J et al. (2005), Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish. Development, 132(16):3731-42.
PMID: 16077092 -
Species: Xenopus
Sample Types: In Vivo
Applications: In VivoReversade B et al. (2005), Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. Cell, 123(6):1147-60.
PMID: 16360041 -
Species: Xenopus
Sample Types: Whole Cells
Applications: BioassayNg RK et al. (2005), Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer. Proc. Natl. Acad. Sci. U.S.A., 102(6):1957-62.
PMID: 15684086 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayAlthini S et al. (2004), Blocked MAP kinase activity selectively enhances neurotrophic growth responses. Mol. Cell. Neurosci., 25(2):345-54.
PMID: 15019950 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayWakamatsu Y et al. (2004), Multiple roles of Sox2, an HMG-box transcription factor in avian neural crest development. Dev. Dyn., 229(1):74-86.
PMID: 14699579 -
Species: Human
Applications: BioassayOren A et al. (2004), hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation. Gene, 331(0):17-31.
PMID: 15094188 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBlair DG et al. (2004), Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis. J. Immunol., 173(10):5914-7.
PMID: 15528323 -
Species: Chicken
Sample Types: Whole Tissue
Applications: BioassayMarklund M et al. (2004), Retinoic acid signalling specifies intermediate character in the developing telencephalon. Development, 131(17):4323-32.
PMID: 15294870 -
Species: Ovine
Sample Types: Whole Cells
Applications: BioassayPierre A et al. (2004), Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells. J. Mol. Endocrinol., 33(3):805-17.
PMID: 15591037 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBinnerts ME et al. (2004), Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins. Biochem. Biophys. Res. Commun., 315(2):272-80.
PMID: 14766204 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMoser M et al. (2003), BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol. Cell. Biol., 23(16):5664-79.
PMID: 12897139 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayViti J et al. (2003), Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2. J. Neurosci., 23(13):5919-27.
PMID: 12843296 -
Species: Rat
Sample Types: In Vivo
Applications: In VivoAhn SH et al. (2003), Effect of recombinant human bone morphogenetic protein-4 with carriers in rat calvarial defects. J. Periodontol., 74(6):787-97.
PMID: 12886988 -
Species: Rabbit
Sample Types: Whole Cells
Applications: BioassayFischer A et al. (2002), FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit. Curr. Biol., 12(21):1807-16.
PMID: 12419180 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIn Kyoung Mah et al. (0), Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation. Dev Bio416(1):82-97.
PMID: 27312576
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Customer Reviews (8)
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 10/13/2020
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 10/13/2020
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Application: Stem/Immune cell maintenance or differentiationReason for Rating: robust response in our differentiation; stable and repeatable results when used as described.Verified Customer | Posted 07/24/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 05/28/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 04/07/2020
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 12/21/2017
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Application: CellProlifVerified Customer | Posted 05/19/2016
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Application: In vitro bioactivity in cell cultureReason for Rating: The product worked really well and it was easy to handleVerified Customer | Posted 05/18/2016
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FAQs
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What is the half-life of a recombinant or natural protein in culture at 37 °C?
R&D Systems has not determined the half-life of recombinant or natural proteins in culture. For cell-based bioassays, the incubation period of the protein with the cells typically ranges from 48 to 96 hours. Assay conditions for each protein will need to be optimized by each researcher.
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Can Recombinant Human BMP-4 Protein (Catalog # 314-BP or 314-BP/CF) be reconstituted in PBS or water?
Recombinant Human BMP-4 (Catalog # 314-BP or 314-BP/CF) needs to be reconstituted to 50-200 μg/mL in sterile 4 mM HCl containing 0.1% BSA, or 4 mM HCl to ensure optimal recovery, stability, and activity. This protein is hydrophobic by nature, so it requires an acidic buffer for reconstitution to go completely into solution. Stability testing has been evaluated on the protein with these reconstitution conditions; we can guarantee performance under these reconstitution conditions. When the protein is diluted with the cell culture media or buffers to the working concentration, the concentration of the acid should be buffered or negligible.