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Voltage-gated Potassium Channel Blockers Products

21 results for "Voltage-gated Potassium Channel Blockers" in Products

21 results for "Voltage-gated Potassium Channel Blockers" in Products

Voltage-gated Potassium Channel Blockers Products

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

Alternate Names: Tikosyn,UK 68798
Chemical Name: 1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
Purity: ≥98% (HPLC)
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

Non-selective KV channel blocker

Alternate Names: 4-AP
Purity: ≥98% (HPLC)
Non-selective KV channel blocker

Cell-permeable Ca2+ chelator

Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)
Purity: ≥95% (HPLC)
Cell-permeable Ca2+ chelator

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

Chemical Name: N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
Purity: ≥98% (HPLC)
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents

Chemical Name: 10,10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride
Purity: ≥98% (HPLC)
Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents

CaM kinase II inhibitor; also K+ channel blocker (KV)

Chemical Name: N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide
Purity: ≥98% (HPLC)
CaM kinase II inhibitor; also K+ channel blocker (KV)

Potent Kv2.1 and Kv2.2 channel blocker

Purity: ≥95% (HPLC)
Potent Kv2.1 and Kv2.2 channel blocker

H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Chemical Name: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Purity: ≥98% (HPLC)
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Potent and selective Iks channel blocker

Chemical Name: N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide
Purity: ≥98% (HPLC)
Potent and selective Iks channel blocker

Kv11.1 (hERG) channel blocker

Chemical Name: 1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride
Purity: ≥97% (HPLC)
Kv11.1 (hERG) channel blocker

Potent KV1.3 channel blocker

Chemical Name: 4-(4-Phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
Purity: ≥98% (HPLC)
Potent KV1.3 channel blocker

Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Alternate Names: Hismanal
Chemical Name: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Purity: ≥98% (HPLC)
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

KV7 (KCNQ) channel blocker

Alternate Names: DuP 996
Chemical Name: 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one dihydrochloride
Purity: ≥98% (HPLC)
KV7 (KCNQ) channel blocker

Blocker of KV1.3 and KV1.4 channels

Chemical Name: 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine hydrochloride
Purity: ≥98% (HPLC)
Blocker of KV1.3 and KV1.4 channels

Inactive analog of KN 93. K+ channel (Kv) blocker

Chemical Name: 2-[N-(4'-Methoxybenzenesulfonyl)]amino-N-(4'-chlorophenyl)-2-propenyl-N-methylbenzylamine phosphate
Purity: ≥98% (HPLC)
Inactive analog of KN 93. K+ channel (Kv) blocker

Blocker of KV1.5 channel and IKur current

Alternate Names: Diphenyl phosphine oxide-1
Chemical Name: [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphine oxide
Purity: ≥98% (HPLC)
Blocker of KV1.5 channel and IKur current

IKs blocker. Also blocks ICFTR

Chemical Name: trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide
Purity: ≥98% (HPLC)
IKs blocker. Also blocks ICFTR

IKs blocker. Enantiomer of Chromanol 293B (Cat. No. 1412)

Chemical Name: N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide
Purity: ≥98% (HPLC)
IKs blocker. Enantiomer of Chromanol 293B (Cat. No. 1412)

Potent and selective IKs blocker

Chemical Name: 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
Purity: ≥98% (HPLC)
Potent and selective IKs blocker

Potent and selective KV7.2 inhibitor; brain penetrant

Chemical Name: (S)-2-Phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide
Purity: ≥98% (HPLC)
Potent and selective KV7.2 inhibitor; brain penetrant

HIF-PH inhibitor; erythropoietic

Alternate Names: FG 4592
Chemical Name: N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine
Purity: ≥98% (HPLC)
HIF-PH inhibitor; erythropoietic
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