Chromanol 293B

Tocris Bioscience, part of Bio-Techne | Catalog # 1412

IKs blocker. Also blocks ICFTR
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Key Product Details

Description

IKs blocker. Also blocks ICFTR

View all Voltage-gated Potassium Channel Blockers »

Product Description

Chromanol 293B is a blocker of the slow delayed rectifier K+ current (IKs) (IC50 = 1-10 μM). Also blocks the CFTR chloride current (ICFTR) (IC50 = 19 μM).

Enantiomer also available.

Product Specifications

Molecular Weight

324.39

Formula

C15H20N2O4S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

trans-N-[6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide

CAS Number

163163-23-3

PubChem ID

121846

InChI Key

HVSJHHXUORMCGK-UONOGXRCSA-N

SMILES

O[C@H]1[C@H](N(C)S(=O)(CC)=O)C2=C(C=CC(C#N)=C2)OC(C)1C.O[C@@H]3[C@@H](N(C)S(=O)(CC)=O)C4=C(C=CC(C#N)=C4)OC(C)3C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.44 100
Ethanol 6.49 20

Preparing Stock Solutions for Chromanol 293B

The following data is based on the product molecular weight 324.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL
10 mM 0.31 mL 1.54 mL 3.08 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Chromanol 293B

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Chromanol 293B

For research use only

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