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M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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274 results for "M-CSF" in Products

274 results for "M-CSF" in Products

M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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Analyzed by SEC-MALS

Source: E. coli
Accession #: Q3U4F9
Applications: BA
(2)

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

The Mouse Cytokine Array, Panel A utilizes capture antibodies spotted onto a nitrocellulose membrane to allow high-throughput multi-analyte profiling of 40 cytokines, chemokines, and more in a single sample.
(3)

Analyzed by SEC-MALS

Source: CHO
Accession #: P09603
Applications: BA
Recombinant Human M-CSF (CHO-expressed) Protein Bioactivity
Sensitivity: 47.3 pg/mL
Applications: ELISA
Assay Range: 78.1 - 5,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine)
Human M-CSF ELISA Cell Culture Supernates/Saliva/Urine Standard Curve
(3)

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
(3)

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Detection of selected mouse cytokines in Balb/3T3 Cell Line Lysate
(3)
Sensitivity: 0.486 pg/mL
Applications: ELISA
Assay Range: 6.25 - 400 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
(3)

Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.

Applications: Simple Plex
Custom Simple Plex Assay Panel

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

(3)

Analyzed by SEC-MALS,

Source: E. coli
Accession #: NP_757350
Applications: BA
(3)

Simple Plex Human M-CSF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
Ella Automated ELISA Platform and Simple Plex Human M-CSF Assay
(3)

Animal-Free.

Source: E. coli
Accession #: NP_757350.2
Applications: BA
Recombinant Human M-CSF GMP Protein Bioactivity
(3)

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Assay Range: 15.6 - 1,000 pg/mL
Applications: ELISA
Human M-CSF ELISA Standard Curve

Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies

Assay Range: 15.6 - 1,000 pg/mL
Applications: ELISA
Mouse M-CSF ELISA Standard Curve

Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies

Multiple Proteins in TNF-alpha-treated Balb/3T3 Cells were Assessed using the Mouse Angiogenesis Array.

Intended for preclinical researchers who may transition to GMP M-CSF for their clinical work

Source: E. coli
Accession #: NP_757350.2
Applications: BA
R&D Systems Animal-Free Recombinant Proteins
Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, Neut
Cell Proliferation Induced by M-CSF and Neutralization by Human M-CSF Antibody.
(4)
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