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M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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86 results for "M-CSF" in Products

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M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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86 results for "M-CSF" in Products

Analyzed by SEC-MALS

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Analyzed by SEC-MALS,

Simple Plex Human M-CSF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Animal-Free.

WB

Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies

Intended for preclinical researchers who may transition to GMP M-CSF for their clinical work

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies

Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies

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