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M-CSF: Simple Plex

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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5 results for "M-CSF Simple Plex" in Products

M-CSF: Simple Plex

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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5 results for "M-CSF Simple Plex" in Products

Simple Plex Human M-CSF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Simple Plex Mouse/Rat M-CSF assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Catalog #: 898205
Ctrl

Control for use with Human M-CSF Simple Plex Cartridge Kit

Catalog #: 897104

Control for use with Mouse/Rat M-CSF Simple Plex Assay Cartridge Kit

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