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M-CSF: Proteins and Enzymes
M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.
7 results for "M-CSF Proteins and Enzymes" in Products
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M-CSF: Proteins and Enzymes
M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.
7 results for "M-CSF Proteins and Enzymes" in Products
BA
Mammalian-expressed CHO Version Available!
| Source : | E. coli |
| Accession # : | NP_757350 |
| Applications : | Bioactivity |
BA
| Source : | E. coli |
| Accession # : | Q3U4F9 |
| Applications : | Bioactivity |
BA
Animal-Free. Earn double rewards for reviews
| Source : | E. coli |
| Accession # : | NP_757350.2 |
| Applications : | Bioactivity |
BA
| Source : | CHO |
| Accession # : | P09603 |
| Applications : | Bioactivity |
Catalog #:
AFL216
BA
Also available, GMP M-CSF Protein, Catalog # 216-GMP! Animal-free and manufactured under GMP guidelines for therapeutic manufacturing applications.
| Source : | E. coli |
| Accession # : | NP_757350.2 |
| Applications : | Bioactivity |
Catalog #:
PRD216
BA
Supplied as ready-to-use 5 ug protein balls
| Source : | E. coli |
| Accession # : | NP_757350 |
| Applications : | Bioactivity |
Catalog #:
BT216
BA
Biotinylated
| Source : | E. coli |
| Accession # : | NP_757350.2 |
| Applications : | Bioactivity |
