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M-CSF: Proteins and Enzymes

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

7 results for "M-CSF Proteins and Enzymes" in Products

M-CSF: Proteins and Enzymes

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

7 results for "M-CSF Proteins and Enzymes" in Products

Mammalian-expressed CHO Version Available!

Animal-Free. Earn double rewards for reviews

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Also available, GMP M-CSF Protein, Catalog # 216-GMP! Animal-free and manufactured under GMP guidelines for therapeutic manufacturing applications.

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Supplied as ready-to-use 5 ug protein balls

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Biotinylated

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