Recombinant Mouse M-CSF Protein
R&D Systems, Inc. a Bio-Techne Brand
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Key Product Details
Source: | E. coli |
Accession #: | Q3U4F9 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations for Recombinant Mouse M-CSF Protein (531)
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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse M-CSF Protein include:
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Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJM Han et al. (2023), Polysaccharides from Annona�muricata leaves protect against cisplatin?induced cytotoxicity in macrophages by alleviating mitochondrial dysfunction Molecular Medicine Reports, 27(1).
PMID: 36453199 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Liu et al. (2022), Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways International Journal of Molecular Sciences, 23(5).
PMID: 35270008 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySJ Hwang et al. (2022), miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1 Cell Death and Differentiation, 0(0).
PMID: 34974535 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Shen et al. (2022), Plumbagin is a NF-kappaB-Inducing Kinase Inhibitor with Dual Anabolic and Anti-Resorptive Effects that Prevents Menopausal-Related Osteoporosis in Mice The Journal of Biological Chemistry, 0(0):101767.
PMID: 35235833 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Guo et al. (2022), Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production The Journal of Biological Chemistry, 0(0):101775.
PMID: 35257748 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Zuo et al. (2022), Inhibition of myeloid PD-L1 suppresses osteoclastogenesis and cancer bone metastasis Cancer Gene Therapy, 0(0).
PMID: 35256753 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureC Yang et al. (2022), TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss Autophagy, 0(0).
PMID: 35255774 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureYJ Lee et al. (2022), Chemical Modulation of SQSTM1/p62-mediated Xenophagy that Targets a Broad Range of Pathogenic Bacteria Autophagy, 0(0).
PMID: 35316156 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Ma et al. (2022), P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca2+/calcineurin signaling Molecular Medicine Reports, 25(5).
PMID: 35266012 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureZI Mendel et al. (2022), Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages Journal of Cell Science, 0(0).
PMID: 35107133 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKK Richardson et al. (2022), Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice International Journal of Molecular Sciences, 23(2).
PMID: 35054859 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Mela et al. (2022), The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific Cells, 11(4).
PMID: 35203379 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Gao et al. (2022), Erythrocyte-derived extracellular vesicles aggravate inflammation by promoting the proinflammatory macrophage phenotype through TLR4-MyD88-NF-kappaB-MAPK pathway Journal of leukocyte biology, 0(0).
PMID: 35411633 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Yang et al. (2022), Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates Science Advances, 8(16):eabm2960.
PMID: 35442725 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureG Li et al. (2022), 7-Ketocholesterol-Induced Micro-RNA-107-5p Increases Number and Activity of Osteoclasts by Targeting MKP1 International Journal of Molecular Sciences, 23(7).
PMID: 35409056 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Fierro et al. (2022), Dual-sgRNA CRISPR/Cas9 knockout of PD-L1 in human U87 glioblastoma tumor cells inhibits proliferation, invasion, and tumor-associated macrophage polarization Scientific Reports, 12(1):2417.
PMID: 35165339 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Qiao et al. (2022), Divalent metal cations stimulate skeleton interoception for new bone formation in mouse injury models Nature Communications, 13(1):535.
PMID: 35087048 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJM Kim et al. (2022), Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes Cell Death and Differentiation, 0(0).
PMID: 35169297 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Akasaka et al. (2022), Osteoclast formation from mouse bone marrow cells on micro/nano-scale patterned surfaces Journal of oral biosciences, 0(0).
PMID: 35398598 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Tao et al. (2022), Gut Metabolite Urolithin A Inhibits Osteoclastogenesis and Senile Osteoporosis by Enhancing the Autophagy Capacity of Bone Marrow Macrophages Frontiers in Pharmacology, 13(0):875611.
PMID: 35645801 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Cai et al. (2022), Carnosol inhibits osteoclastogenesis in�vivo and in�vitro by blocking the RANKL?induced NF?kappaB signaling pathway Molecular Medicine Reports, 26(1).
PMID: 35593299 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2022), Peimine suppresses collagen-induced arthritis, activated fibroblast-like synoviocytes and TNFalpha-induced MAPK pathways International immunopharmacology, 111(0):109181.
PMID: 36027853 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Inoue et al. (2022), Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing International Journal of Molecular Sciences, 23(16).
PMID: 36012611 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Sun et al. (2022), Anoctamin 1 controls bone resorption by coupling Cl- channel activation with RANKL-RANK signaling transduction Nature Communications, 13(1):2899.
PMID: 35610255 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Chen et al. (2022), Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation Theranostics, 12(7):3251-3272.
PMID: 35547753 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Qu et al. (2022), Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1 Biomolecules, 12(6).
PMID: 35740904 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureM Jiang et al. (2022), Succinate and inosine coordinate innate immune response to bacterial infection PloS Pathogens, 18(8):e1010796.
PMID: 36026499 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2022), BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1 Cell bioscience, 2022;12(1):70.
PMID: 35619122 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Cai et al. (2022), Long noncoding RNA Gm31629 promotes bone regeneration by maintaining bone marrow mesenchymal stem cells activity PeerJ, 10(0):e13475.
PMID: 35702257 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Cui et al. (2022), Network Pharmacology Deciphers the Action of Bioactive Polypeptide in Attenuating Inflammatory Osteolysis via the Suppression of Oxidative Stress and Restoration of Bone Remodeling Balance Oxidative Medicine and Cellular Longevity, 2022(0):4913534.
PMID: 35578727 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Chen et al. (2022), A Novel Inhibitor INF 39 Promotes Osteogenesis via Blocking the NLRP3/IL-1beta Axis BioMed Research International, 2022(0):7250578.
PMID: 35872849 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2022), Mechanical force regulates root resorption in rats through RANKL and OPG BMC Oral Health, 22(1):290.
PMID: 35842599 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Jie et al. (2022), Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway Journal of Bone Oncology, 35(0):100439.
PMID: 35800294 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Wu et al. (2022), Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses Science Advances, 8(29):eabm7833.
PMID: 35857833 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhang et al. (2022), LysM-positive neurons drive Tuberous Sclerosis Complex (TSC)-associated brain lesions Cellular Signalling, 0(0):110468.
PMID: 36115548 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Azimova et al. (2022), Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis Oncogene, 18(6):e1010417.
PMID: 35731824 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMI Alam et al. (2022), NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides Oncogene, 23(11).
PMID: 35682777 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Tian et al. (2022), Melatonin inhibits osteoclastogenesis via RANKL/OPG suppression mediated by Rev-Erbalpha in osteoblasts Oncogene, 0(0).
PMID: 35726597 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Li et al. (2022), Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages Oncogene, 109(0):108907.
PMID: 35691271 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Hoyler et al. (2022), Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants JCI Insight, 7(13).
PMID: 35801586 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMH Wu et al. (2022), Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo Biomedicines, 10(10).
PMID: 36289618 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zou et al. (2022), Interleukin-19 Promotes Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy Investigative Ophthalmology Visual Science, 2022;63(8):9.
PMID: 35816041 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureM Tomimatsu et al. (2022), Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling Scientific Reports, 12(1):16656.
PMID: 36198906 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAP Shaik et al. (2022), Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses BioMed Research International, 2022(0):9470845.
PMID: 36246991 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYF Wang et al. (2022), Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer Cell Death Disease, 2022;13(8):748.
PMID: 36038549 -
Species: Mouse
Sample Types: Whole Cell
JX Sun et al. (2022), Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function Acta pharmacologica Sinica, 0(0).
PMID: 36229601 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Tsukasaki et al. (2022), Periosteal stem cells control growth plate stem cells during postnatal skeletal growth Oncogene, 13(1):4166.
PMID: 35851381 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Wang et al. (2022), Suppression of osteoclast multinucleation via a posttranscriptional regulation-based spatiotemporally selective delivery system Oncogene, 8(26):eabn3333.
PMID: 35767605 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Guo et al. (2022), Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation Theranostics, 12(11):5220-5236.
PMID: 35836819 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Hu et al. (2022), N6-methyladenosine of Socs1 modulates macrophage inflammatory response in different stiffness environments International journal of biological sciences, 18(15):5753-5769.
PMID: 36263168 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Li et al. (2022), HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction Cell Death and Differentiation, 0(0).
PMID: 36182990 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Shi et al. (2022), Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFkappaB p65 pathway Journal of Orthopaedic Translation, 35(0):1-12.
PMID: 35846727 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Cheng et al. (2022), Evaluation of culture conditions for osteoclastogenesis in RAW264.7 cells PLoS ONE, 17(11):e0277871.
PMID: 36395187 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Zhu et al. (2022), Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis Cells, 11(18).
PMID: 36139452 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayCY Chang et al. (2022), Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer Science Advances, 8(46):eabq0615.
PMID: 36383649 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Sun et al. (2022), Mechanistic target of rapamycin complex 1 orchestrates the interplay between hepatocytes and Kupffer cells to determine the outcome of immune-mediated hepatitis Cell Death Disease, 2022;13(12):1031.
PMID: 36494334 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Lin et al. (2022), Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration Nature Communications, 13(1):6869.
PMID: 36369293 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHK Kwon et al. (2022), Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis Embo Molecular Medicine, 0(0):e15284.
PMID: 36354099 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Zhao et al. (2022), Brain milieu induces early microglial maturation through the BAX-Notch axis Nature Communications, 13(1):6117.
PMID: 36253375 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJC Bahr et al. (2022), Divergent regulation of basement membrane trafficking by human macrophages and cancer cells Nature Communications, 13(1):6409.
PMID: 36302921 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJ Wang et al. (2022), Nanoparticle delivery of CD40 siRNA suppresses alloimmune responses by inhibiting activation and differentiation of DCs and macrophages Science Advances, 8(51):eabq3699.
PMID: 36542700 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassaySMT Rahman et al. (2022), Double knockin mice show NF-kappaB trajectories in immune signaling and aging Cell Reports, 41(8):111682.
PMID: 36417863 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Chen et al. (2021), Schistosoma�japonicum cystatin suppresses osteoclastogenesis via manipulating the NF?&kappaB signaling pathway Molecular Medicine Reports, 23(4).
PMID: 33576450 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMG Dorrington et al. (2021), Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol PloS Pathogens, 17(3):e1009395.
PMID: 33684179 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Liu et al. (2021), Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis Nature Communications, 12(1):1832.
PMID: 33758201 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Huo et al. (2021), p300/CBP inhibitor A-485 inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss International immunopharmacology, 94(0):107458.
PMID: 33626422 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Salo et al. (2021), Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns Biomolecules, 11(6).
PMID: 34071440 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureQ Lu et al. (2021), Patchouli Alcohol Modulates the Pregnancy X Receptor/Toll-like Receptor 4/Nuclear Factor Kappa B Axis to Suppress Osteoclastogenesis Frontiers in Pharmacology, 12(0):684976.
PMID: 34177594 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJ Yang et al. (2021), Astragalus polysaccharide attenuates LPS-related inflammatory osteolysis by suppressing osteoclastogenesis by reducing the MAPK signalling pathway Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34080298 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Li et al. (2021), Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling International journal of biological sciences, 17(5):1382-1394.
PMID: 33867853 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Xue et al. (2021), Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response Experimental Molecular Medicine, 2021;0(0).
PMID: 33864025 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMJ Strowitzki et al. (2021), Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses JCI Insight, 0(0).
PMID: 33784253 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEB Byun et al. (2021), Protective Effect of Polysaccharides Extracted from Cudrania tricuspidata Fruit against Cisplatin-Induced Cytotoxicity in Macrophages and a Mouse Model International Journal of Molecular Sciences, 22(14).
PMID: 34299130 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Woo et al. (2021), N-3-Hydroxy Dodecanoyl-DL-homoserine Lactone (OH-dDHL) Triggers Apoptosis of Bone Marrow-Derived Macrophages through the ER- and Mitochondria-Mediated Pathways International Journal of Molecular Sciences, 22(14).
PMID: 34299184 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKH Kim et al. (2021), BCG Cell Wall Skeleton As a Vaccine Adjuvant Protects Both Infant and Old-Aged Mice from Influenza Virus Infection Biomedicines, 9(5).
PMID: 34063125 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJS Kim et al. (2021), Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis Biomedicines, 9(5).
PMID: 34068051 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Wang et al. (2021), STING suppresses bone cancer pain via immune and neuronal modulation Nature Communications, 12(1):4558.
PMID: 34315904 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Guo et al. (2021), Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis Journal of colloid and interface science, 605(0):410-424.
PMID: 34332414 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKH Nilsson et al. (2021), RSPO3 is important for trabecular bone and fracture risk in mice and humans Nature Communications, 12(1):4923.
PMID: 34389713 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Chen et al. (2021), Plastrum testudinis extract suppresses osteoclast differentiation via the NF-&kappaB signaling pathway and ameliorates senile osteoporosis Journal of ethnopharmacology, 276(0):114195.
PMID: 33974944 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Zhang et al. (2021), BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions Cell Death Disease, 2021;12(5):495.
PMID: 33993198 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDK Fix et al. (2021), Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy Aging Cell, 0(0):e13448.
PMID: 34365717 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOJ Sul et al. (2021), 7-ketocholesterol enhances autophagy via the ROS-TFEB signaling pathway in osteoclasts: 7-KC in osteoclasts The Journal of nutritional biochemistry, 0(0):108783.
PMID: 34023424 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Fang et al. (2021), Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion Acta pharmacologica Sinica, 0(0).
PMID: 34381182 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL JanskĆ” et al. (2021), The MEMIC is an ex vivo system to model the complexity of the tumor microenvironment Disease Models Mechanisms, 2021;14(8).
PMID: 34407185 -
Species: Mouse
Sample Types: Whole Cells
Applications: DifferentiationJM Motta et al. (2021), Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation Biomedicines, 9(10).
PMID: 34680504 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCR Park et al. (2021), Rufomycin Exhibits Dual Effects Against Mycobacterium abscessus Infection by Inducing Host Defense and Antimicrobial Activities Frontiers in Microbiology, 12(0):695024.
PMID: 34447358 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Jiang et al. (2021), Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway Cell Reports, 36(12):109720.
PMID: 34551296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJA Carroll et al. (2021), Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia Journal of Neuroinflammation, 18(1):194.
PMID: 34488805 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySN Cho et al. (2021), Ang II-Induced Hypertension Exacerbates the Pathogenesis of Tuberculosis Cells, 10(9).
PMID: 34572127 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Liu et al. (2021), Danlou Tablets Inhibit Atherosclerosis in Apolipoprotein E-Deficient Mice by Inducing Macrophage Autophagy: The Role of the PI3K-Akt-mTOR Pathway Frontiers in Pharmacology, 12(0):724670.
PMID: 34566648 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIY Karkache et al. (2021), Myeloid Lineage Ablation of Phlpp1 Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice International Journal of Molecular Sciences, 22(18).
PMID: 34575866 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Muto et al. (2021), Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis Scientific Reports, 11(1):18778.
PMID: 34548598 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Mae et al. (2021), The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis International Journal of Molecular Sciences, 22(22).
PMID: 34830316 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Gu et al. (2021), Galectin-3 Contributes to the Inhibitory Effect of lalpha,25-(OH)2D3 on Osteoclastogenesis International Journal of Molecular Sciences, 22(24).
PMID: 34948130 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zou et al. (2021), SIRT6 inhibition delays peripheral nerve recovery by suppressing migration, phagocytosis and M2-polarization of macrophages Cell bioscience, 2021;11(1):210.
PMID: 34906231 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Zhuang et al. (2021), Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation Frontiers in Pharmacology, 12(0):762543.
PMID: 34858187 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Amo-Aparic et al. (2021), Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury Theranostics, 11(20):9805-9820.
PMID: 34815787 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Liu et al. (2021), CNC-bZIP protein NFE2L1 regulates osteoclast differentiation in antioxidant-dependent and independent manners Redox Biology, 48(0):102180.
PMID: 34763297 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Kim et al. (2021), TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment Cell Reports, 37(7):110018.
PMID: 34788612 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAE Hinman et al. (2021), Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response Elife, 10(0).
PMID: 34755600 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySW Shin et al. (2021), Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds Nutrients, 14(1).
PMID: 35011011 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Fang et al. (2021), Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway Oxidative Medicine and Cellular Longevity, 2021(0):9661200.
PMID: 35003523 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMB Uccellini et al. (2021), Development of a Macrophage-Based ADCC Assay Vaccines, 9(6).
PMID: 34204268 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2021), ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3 Oxidative Medicine and Cellular Longevity, 2021(0):2896674.
PMID: 34820053 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Liang et al. (2021), PP2Ac&alpha promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNF&alpha production Cell Death and Differentiation, 0(0).
PMID: 33934104 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTT Chu et al. (2021), Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C Nature, 0(0).
PMID: 34290407 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Kawakami et al. (2021), Development of a method for the identification of receptor activator of nuclear factor-&kappaB+ populations in vivo Journal of oral biosciences, 0(0).
PMID: 33516894 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRD Hu et al. (2021), Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity Cell Death Disease, 2021;12(11):1023.
PMID: 34716308 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAS Tooley et al. (2021), The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt The Journal of Biological Chemistry, 0(0):100942.
PMID: 34245780 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMG Dorrington et al. (2021), Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol PloS Pathogens, 17(8):e1009821.
PMID: 34347853 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJS Brunner et al. (2020), Environmental arginine controls multinuclear giant cell metabolism and formation Nat Commun, 11(1):431.
PMID: 31969567 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Cell CultureJR Plemel et al. (2020), Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion Sci Adv, 6(3):eaay6324.
PMID: 31998844 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Saha et al. (2020), Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains Physiol Rep, 8(9):e14441.
PMID: 32385968 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Kohara et al. (2020), Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of Smo in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss Int J Mol Sci, 21(8).
PMID: 32326611 -
Species: Mouse
Applications: In VivoZ Hu et al. (2020), CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia Cell Rep, 31(7):107657.
PMID: 32433966 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJM Kim et al. (2020), A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation Nat Commun, 11(1):2289.
PMID: 32385263 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Huang et al. (2020), Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity Nat. Cell Biol., 0(0).
PMID: 32367047 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureNL Mancini et al. (2020), Perturbed mitochondrial dynamics is a novel feature of colitis that can be targeted to lessen disease Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 32298841 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayH Fan et al. (2020), MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-&kappaB Signaling Pathway Drug Des Devel Ther, 14(0):1377-1389.
PMID: 32308370 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySG Rotman et al. (2020), Development of bone seeker-functionalised microspheres as a targeted local antibiotic delivery system for bone infections J Orthop Translat, 21(0):136-145.
PMID: 32309139 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Sun et al. (2020), Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss Front Pharmacol, 11(0):360.
PMID: 32292342 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Sun et al. (2020), Magnoflorine Suppresses MAPK and NF-&kappaB Signaling to Prevent Inflammatory Osteolysis Induced by Titanium Particles In Vivo and Osteoclastogenesis via RANKL In Vitro Front Pharmacol, 11(0):389.
PMID: 32300300 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Hu et al. (2020), Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-&kappaB and P38 MAPK Signaling Pathways Front Pharmacol, 11(0):385.
PMID: 32317967 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJA Carroll et al. (2020), Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells Sci Rep, 10(1):6654.
PMID: 32313035 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJS Suh et al. (2020), Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model Sci Rep, 10(1):6383.
PMID: 32286430 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2020), F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NF&kappaB signaling pathways Int. J. Biol. Sci., 16(9):1629-1639.
PMID: 32226307 -
Species: Mouse
Sample Types: Whole Cell
Applications: BioassayE van den Bo et al. (2020), Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis J. Biol. Chem., 0(0).
PMID: 32332099 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Goda et al. (2020), Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway PLoS Genet., 16(4):e1008692.
PMID: 32271749 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHS Park et al. (2020), Mycobacterium avium subsp. paratuberculosis MAP1889c Protein Induces Maturation of Dendritic Cells and Drives Th2-biased Immune Responses Cells, 9(4).
PMID: 32290379 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Wu et al. (2020), CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/&beta-Catenin Pathway in Osteoporosis Mol. Ther., 0(0).
PMID: 32304668 -
Species: Mouse
Sample Types: N/A
MB Uccellini et al. (2020), Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice Cell Rep, 31(1):107498.
PMID: 32268088 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureKS Shim et al. (2020), Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice Nutrients, 12(7).
PMID: 32610585 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Tsuchiya et al. (2020), The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-&kappaB signaling downstream of FFAR4 J. Biol. Chem., 0(0).
PMID: 32647011 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Chen et al. (2020), Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling-mediated TRAF6 and c-Src recruitment and NF-&kappaB, MAPK and Akt pathways J. Cell. Mol. Med., 0(0).
PMID: 32604472 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureP Xu et al. (2020), Role of microglia in the dissemination of Zika virus from mother to fetal brain PLoS Negl Trop Dis, 14(7):e0008413.
PMID: 32628667 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJH Kang et al. (2020), Dual role of phosphatidylserine and its receptors in osteoclastogenesis Cell Death Dis, 11(7):497.
PMID: 32612123 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureM Chen et al. (2020), Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-&kappaB signaling pathway Bioact Mater, 5(4):880-890.
PMID: 32637751 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureT Velletri et al. (2020), Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin Cell Death Differ., 0(0).
PMID: 32694652 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Maruyama et al. (2020), Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages Cell Rep, 32(2):107906.
PMID: 32668247 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureYR Kim et al. (2020), Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis Sci Rep, 10(1):4570.
PMID: 32165681 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Zhi et al. (2020), Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C-Src and inhibiting NF-&kappaB, MAPK and AKT pathways J. Cell. Mol. Med., 0(0).
PMID: 32185887 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureL Wang et al. (2020), Osthole-loaded N-octyl-O-sulfonyl chitosan micelles (NSC-OST) inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in rats J. Cell. Mol. Med., 0(0).
PMID: 32126148 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureYS Kim et al. (2020), The Peroxisome Proliferator-Activated Receptor &alpha- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus Infections Cells, 9(3).
PMID: 32155958 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureMS Ferguson et al. (2020), Transient Inhibition of PI3K&delta Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus Mol. Ther., 0(0).
PMID: 32145202 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Zuo et al. (2020), Differential regulation of breast cancer bone metastasis by PARP1 and PARP2 Nat Commun, 11(1):1578.
PMID: 32221289 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureN Uesato et al. (2020), Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor Biol. Pharm. Bull., 43(2):325-333.
PMID: 32009119 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureFQ Kong et al. (2020), Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury J Neuroinflammation, 17(1):62.
PMID: 32066456 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureD Zhang et al. (2020), Knockdown of Tcirg1 inhibits large-osteoclast generation by down-regulating NFATc1 and IP3R2 expression PLoS ONE, 15(8):e0237354.
PMID: 32790690 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Rosendahl et al. (2020), CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice The Journal of Biological Chemistry, 0(0).
PMID: 33303631 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureX Tong et al. (2020), Overexpression of c-Fos reverses osteoprotegerin-mediated suppression of osteoclastogenesis by increasing the Beclin1-induced autophagy Journal of Cellular and Molecular Medicine, 0(0).
PMID: 33277741 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Liu et al. (2020), Maackiain dampens osteoclastogenesis via attenuating RANKL-stimulated NF-&kappaB signalling pathway and NFATc1 activity J. Cell. Mol. Med., 0(0).
PMID: 32939977 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDHH Molstad et al. (2020), Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL J Biol Chem, 0(0).
PMID: 33012705 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureAT Holdbrooks et al. (2020), Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase PLoS ONE, 15(11):e0241850.
PMID: 33166339 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Hagan et al. (2020), CSF1R signaling is a regulator of pathogenesis in progressive MS Cell Death Dis, 11(10):904.
PMID: 33097690 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureT Okui et al. (2020), The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone Journal of Bone Oncology, 26(0):100330.
PMID: 33204606 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Wang et al. (2020), Dopamine suppresses osteoclast differentiation via cAMP/PKA/CREB pathway Cell Signal, 78(0):109847.
PMID: 33242564 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJS Kim et al. (2020), Toxoplasma gondii GRA9 Regulates the Activation of NLRP3 Inflammasome to Exert Anti-Septic Effects in Mice Int J Mol Sci, 21(22).
PMID: 33182702 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureL Xiao et al. (2020), Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-&kappaB signaling pathways Aging (Albany NY), 12(21):21706-21729.
PMID: 33176281 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureB Chu et al. (2020), Nepetin inhibits osteoclastogenesis by inhibiting RANKL-induced activation of NF-&kappaB and MAPK signalling pathway, and autophagy J Cell Mol Med, 0(0).
PMID: 33135301 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Yonebayash et al. (2020), MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation J Cell Mol Med, 0(0).
PMID: 33140535 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMJ Park et al. (2020), Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells Journal of Translational Medicine, 18(1):483.
PMID: 33317573 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureCH Lee et al. (2020), NLRP3 Inflammasome Activation Is Involved in LPA1-Mediated Brain Injury after Transient Focal Cerebral Ischemia Int J Mol Sci, 21(22).
PMID: 33202644 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Najafova et al. (2020), RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk Cell Death Differ., 0(0).
PMID: 32901120 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureG Yang et al. (2020), Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1&beta production Cell Mol Immunol, 0(0).
PMID: 33235386 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Yang et al. (2020), M2 macrophage-derived exosomes promote angiogenesis and growth of pancreatic ductal adenocarcinoma by targeting E2F2 Mol Ther, 0(0).
PMID: 33221435 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYS Lee et al. (2020), Regulation of bone metabolism by megakaryocytes in a paracrine manner Sci Rep, 10(1):2277.
PMID: 32042021 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTT Tang et al. (2020), Extracellular vesicle-encapsulated IL-10 as novel nanotherapeutics against ischemic AKI Sci Adv, 6(33):eaaz0748.
PMID: 32851154 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Peng et al. (2020), Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo Drug Des Devel Ther, 14(0):3435-3447.
PMID: 32943842 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Ikezu et al. (2020), Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities Mol. Psychiatry, 0(0).
PMID: 32071385 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayME McCauley et al. (2020), C9orf72 in myeloid cells suppresses STING-induced inflammation Nature, 585(7823):96-101.
PMID: 32814898 -
G Gupta et al. (2020), The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Regulating CD4+ T Helper Cell Response Cell Reports, 33(11):108513.
PMID: 33326783 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRK Arya et al. (2020), Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation The Journal of Biological Chemistry, 296(0):100129.
PMID: 33460921 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Liu et al. (2020), Progranulin inhibits LPS-induced macrophage M1 polarization via NF-?B and MAPK pathways BMC Immunol., 21(1):32.
PMID: 32503416 -
Species: Transgenic Mouse
Sample Types: Spheroid
Applications: BioassayAE Engler et al. (2020), Airway-Associated Macrophages in Homeostasis and Repair Cell Reports, 33(13):108553.
PMID: 33378665 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Wang et al. (2020), PD-1 blockade inhibits osteoclast formation and murine bone cancer pain J. Clin. Invest., 0(0).
PMID: 32484460 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureK Miyagawa et al. (2020), Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo JCI Insight, 0(0).
PMID: 32078587 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureG Cerrato et al. (2020), Oleate-induced aggregation of LC3 at the trans-Golgi network is linked to a protein trafficking blockade Cell Death and Differentiation, 0(0).
PMID: 33335289 -
Species: Feline
Sample Types: Whole Cells
Applications: Cell CultureS Lee et al. (2020), Transcriptomic profiling of feline teeth highlights the role of matrix metalloproteinase 9 (MMP9) in tooth resorption Sci Rep, 10(1):18958.
PMID: 33144645 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Liu et al. (2020), NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis Cell Death Dis, 11(2):129.
PMID: 32071294 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureSY Kim et al. (2020), Mycobacterium tuberculosis Rv2626c-derived peptide as a therapeutic agent for sepsis Embo Molecular Medicine, 12(12):e12497.
PMID: 33258196 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureM Timmen et al. (2020), The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis Sci Rep, 10(1):20510.
PMID: 33239699 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureZ Liu et al. (2020), Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-&kappaB Pathway Mediators of Inflammation, 2020(0):1926947.
PMID: 33312069 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBH Zou et al. (2020), Oridonin ameliorates inflammation-induced bone loss in mice via suppressing DC-STAMP expression Acta Pharmacol. Sin., 0(0).
PMID: 32753731 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHT Pham et al. (2020), Collagen VIalpha2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFalpha signaling Sci Rep, 10(1):13749.
PMID: 32792616 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Qian et al. (2020), Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis J. Cell. Mol. Med., 0(0).
PMID: 32790170 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2020), Tectoridin inhibits osteoclastogenesis and bone loss in a murine model of ovariectomy-induced osteoporosis Exp. Gerontol., 140(0):111057.
PMID: 32798609 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySJ Moon et al. (2020), Ablation of Gadd45beta ameliorates the inflammation and renal fibrosis caused by unilateral ureteral obstruction J. Cell. Mol. Med., 0(0).
PMID: 32570293 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Zhang et al. (2020), Knockdown of Tcirg1 inhibits large-osteoclast generation by down-regulating NFATc1 and IP3R2 expression PLoS ONE, 15(8):e0237354.
PMID: 32790690 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Chen et al. (2020), Dendritic cells-derived interferon-lambda1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis Cell Death Dis, 11(6):414.
PMID: 32488049 -
Species: Mouse Mouse
Sample Types: Whole Cells
Applications: BioassayME McCauley et al. (2020), C9orf72 in myeloid cells suppresses STING-induced inflammation Nature, 585(7823):96-101.
PMID: 32814898 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYW Ge et al. (2020), The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo Oxid Med Cell Longev, 2020(0):1404915.
PMID: 32587656 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Zhang et al. (2020), Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade Theranostics, 10(15):6638-6660.
PMID: 32550895 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Cui et al. (2019), Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 0(0).
PMID: 30676324 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCL Chan et al. (2019), L-caldesmon alters cell spreading and adhesion force in RANKL-induced osteoclasts J. Biomed. Sci., 26(1):12.
PMID: 30678675 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNKY Wee et al. (2019), Skeletal phenotype of the neuropeptide Y knockout mouse Neuropeptides, 73(0):78-88.
PMID: 30522780 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Murugan et al. (2019), The neurosteroid, pregnenolone promotes degradation of key proteins in the innate immune signalling to suppress inflammation J. Biol. Chem., 0(0).
PMID: 30647133 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Rao et al. (2019), Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways EBioMedicine, 0(0).
PMID: 30738832 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Ahn et al. (2019), Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host Nat Microbiol, 0(0).
PMID: 30804542 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Zhu et al. (2019), CD200 Modulates S. aureus-Induced Innate Immune Responses Through Suppressing p38 Signaling Int J Mol Sci, 20(3).
PMID: 30717437 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Aguayo et al. (2019), Fasciola hepatica GST downregulates NF-?B pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model Sci Rep, 9(1):2275.
PMID: 30783117 -
Species: Mouse
Applications: BioassayQ Sun et al. (2019), A potential therapeutic target for regulating osteoporosis via suppression of osteoclast differentiation J Dent, 0(0).
PMID: 30716449 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Jin et al. (2019), Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice J. Cell. Mol. Med., 23(1):522-534.
PMID: 30451360 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTS Kim et al. (2019), SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions Autophagy, 0(0):20-Jan.
PMID: 30774023 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Bergsma et al. (2019), Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82 Bone Rep, 10(0):100196.
PMID: 30788390 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Handa et al. (2019), Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis J. Leukoc. Biol., 0(0).
PMID: 30835899 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Paik et al. (2019), Rg6, a rare ginsenoside, inhibits systemic inflammation through the induction of interleukin-10 and microRNA-146a Sci Rep, 9(1):4342.
PMID: 30867482 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Lee et al. (2019), Characterisation of genes differentially expressed in macrophages by virulent and attenuated Mycobacterium tuberculosis through RNA-Seq analysis Sci Rep, 9(1):4027.
PMID: 30858471 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Funk et al. (2019), The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4 Sci Rep, 9(1):4515.
PMID: 30872638 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHS Park et al. (2019), Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential Sci Rep, 9(1):4246.
PMID: 30862819 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2019), Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy Nat. Med., 0(0).
PMID: 30833750 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Singh et al. (2019), Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway Nat Commun, 10(1):89.
PMID: 30626868 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNS Adapala et al. (2019), PI3K activation increases SDF-1 production and number of osteoclast precursors, and enhances SDF-1-mediated osteoclast precursor migration Bone Rep, 10(0):100203.
PMID: 30989092 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Zhao et al. (2019), Discovery of new inhibitors against both NF-?B and osteoclastogenesis from in-house library with ?, ?-unsaturated-enone fragment Bioorg. Chem., 87(0):638-646.
PMID: 30947099 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHK Kwon et al. (2019), A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice Exp. Mol. Med., 51(4):50.
PMID: 31028244 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNE Putnam et al. (2019), MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis PLoS Pathog., 15(4):e1007744.
PMID: 30978245 -
Species: Mouse
Sample Types: Tumor Cells
Applications: BioassayZ Kun et al. (2019), Tumor derived EDIL3 modulates the expansion and osteoclastogenesis of myeloid derived suppressor cells in murine breast cancer model J Bone Oncol, 16(0):100238.
PMID: 31110935 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySW Wong et al. (2019), Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget's disease Cell Death Differ., 0(0).
PMID: 31076632 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLL Lv et al. (2019), Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury Cell Death Differ., 0(0).
PMID: 31097789 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Lotinun et al. (2019), Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression J. Clin. Invest., 130(0).
PMID: 31112135 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureK Tsuchiya et al. (2019), Caspase-1 initiates apoptosis in the absence of gasdermin D Nat Commun, 10(1):2091.
PMID: 31064994 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJ Meng et al. (2019), Stachydrine prevents LPS-induced bone loss by inhibiting osteoclastogenesis via NF-ĆĀŗB and Akt signalling J. Cell. Mol. Med., 0(0).
PMID: 31328430 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJ Mei et al. (2019), Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage Theranostics, 9(13):3707-3722.
PMID: 31281508 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureYS Yang et al. (2019), Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis Nat Commun, 10(1):2958.
PMID: 31273195 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Sun et al. (2019), Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome Cell Death Dis, 10(8):542.
PMID: 31316052 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Xiong et al. (2019), Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation Cell Rep, 28(3):804-818.e7.
PMID: 31315056 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySS Dykes et al. (2019), Cathepsin L secretion by host and neoplastic cells potentiates invasion Oncotarget, 10(53):5560-5568.
PMID: 31565189 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWS Lian et al. (2019), MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12 Cell Death Dis, 10(10):705.
PMID: 31543513 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Sun et al. (2019), The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-?b signaling Redox Biol, 28(0):101309.
PMID: 31487581 -
Species: Mouse
Sample Types: Whole Cells
Applications: DifferentiationS Nair et al. (2019), Adult stem cell deficits drive Slc29a3 disorders in mice Nat Commun, 10(1):2943.
PMID: 31270333 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureY Wang et al. (2019), Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis Int J Nanomedicine, 14(0):7839-7849.
PMID: 31576127 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Avasarala et al. (2019), PRMT6 promotes lung tumor progression via the alternate activation of tumor-associated macrophages Mol. Cancer Res., 0(0).
PMID: 31619507 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Cell CultureRW Wu et al. (2019), MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of Osteoclastogenesis Int J Mol Sci, 20(20).
PMID: 31627291 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Wu et al. (2019), The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation PLoS Pathog., 15(10):e1008093.
PMID: 31600344 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Newton et al. (2019), Cleavage of RIPK1 by caspase-8�is crucial for limiting apoptosis and necroptosis Nature, 0(0).
PMID: 31511692 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Nagai et al. (2019), P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation J. Clin. Invest., 0(0).
PMID: 31638598 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAL Rocha et al. (2019), Inhibitory effects of dabigatran etexilate, a direct thrombin inhibitor, on osteoclasts and osteoblasts Thromb. Res., 186(0):45-53.
PMID: 31883999 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySK Pore et al. (2019), A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption Mol. Cancer Ther., 0(0).
PMID: 31784454 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Hu et al. (2019), The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-kappaB and CD9/gp130/STAT3 signalling pathway J. Cell. Mol. Med., 0(0).
PMID: 31837208 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA El-Kenawi et al. (2019), Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer Br. J. Cancer, 121(7):556-566.
PMID: 31417189 -
Species: Mouse
Sample Types: Whole Tissue
Applications: Tissue CultureAE Ciecko et al. (2019), Interleukin-27 Is Essential for Type 1 Diabetes Development and Sj�gren Syndrome-like Inflammation Cell Rep, 29(10):3073-3086.e5.
PMID: 31801074 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Huang et al. (2019), Diterpenoids from the aerial parts of Flueggea acicularis and their activity against RANKL-induced osteoclastogenesis Bioorg. Chem., 0(0):103453.
PMID: 31787342 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2019), Phillyrin Attenuates Osteoclast Formation and Function and Prevents LPS-Induced Osteolysis in Mice Front Pharmacol, 10(0):1188.
PMID: 31680965 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySV Novitskiy et al. (2019), Gas6/MerTK signaling is negatively regulated by NF-&kappaB and supports lung carcinogenesis Oncotarget, 10(66):7031-7042.
PMID: 31903163 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHJ Park et al. (2019), Lycorine Attenuates Autophagy in Osteoclasts via an Axis of mROS/TRPML1/TFEB to Reduce LPS-Induced Bone Loss Oxid Med Cell Longev, 2019(0):8982147.
PMID: 31687088 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureJ Lee et al. (2019), Mitofusin 2-Deficiency Suppresses Mycobacterium tuberculosis Survival in Macrophages Cells, 8(11).
PMID: 31671648 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAM Mattson et al. (2019), Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice J. Biol. Chem., 0(0).
PMID: 31189651 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Gilmour et al. (2019), Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors Epigenetics Chromatin, 12(1):33.
PMID: 31164147 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZQ Hu et al. (2019), Rab32 GTPase, as a direct target of miR-30b/c, controls the intracellular survival of Burkholderia pseudomallei by regulating phagosome maturation PLoS Pathog., 15(6):e1007879.
PMID: 31199852 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Hu et al. (2019), Dehydrocostus lactone attenuates osteoclastogenesis and osteoclast-induced bone loss by modulating NF-?B signalling pathway J. Cell. Mol. Med., 0(0).
PMID: 31225720 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCP Hans et al. (2019), Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization Sci Rep, 9(1):7999.
PMID: 31142802 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Chen et al. (2019), Sfrp4 repression of the Ror2/Jnk cascade in osteoclasts protects cortical bone from excessive endosteal resorption Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 31239337 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySS Welc et al. (2019), Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy Nat Commun, 10(1):2788.
PMID: 31243277 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Marino et al. (2019), Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice EBioMedicine, 44(0):452-466.
PMID: 31151929 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Lucas et al. (2018), Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss Nat Commun, 9(1):55.
PMID: 29302038 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayI Di Ceglie et al. (2018), Fc? receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis Arthritis Res. Ther., 20(1):80.
PMID: 29720243 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Quan et al. (2018), LncRNA-AK131850 Sponges MiR-93-5p in Newborn and Mature Osteoclasts to Enhance the Secretion of Vascular Endothelial Growth Factor a Promoting Vasculogenesis of Endothelial Progenitor Cells Cell. Physiol. Biochem., 46(1):401-417.
PMID: 29590659 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Berndt et al. (2018), Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach Stem Cell Res Ther, 9(1):117.
PMID: 29703251 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJE Draper et al. (2018), A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects PLoS Genet., 14(1):e1007127.
PMID: 29300724 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Kinsella et al. (2018), Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation J Neuroinflammation, 15(1):130.
PMID: 29720226 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHJ Koh et al. (2018), CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22 Exp. Mol. Med., 50(5):62.
PMID: 29760437 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Quach et al. (2018), Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice mSphere, 3(1).
PMID: 29299532 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Jin et al. (2018), Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor ?B Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-?B Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages Med. Sci. Monit., 24(0):2569-2577.
PMID: 29698379 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySM Jung et al. (2018), Fraxinellone Attenuates Rheumatoid Inflammation in Mice Int J Mol Sci, 19(3).
PMID: 29533969 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Langer et al. (2018), Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2 PLoS ONE, 13(2):e0193207.
PMID: 29474374 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Cui et al. (2018), IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages J. Immunol., 0(0).
PMID: 29563175 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Sun et al. (2018), RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function J. Immunol., 0(0).
PMID: 29507108 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Hu et al. (2018), SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages J. Immunol., 0(0).
PMID: 29784761 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Li et al. (2018), MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages J. Immunol., 0(0).
PMID: 29563176 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySB Jung et al. (2018), Reduced oxidative capacity in macrophages results in systemic insulin resistance Nat Commun, 9(1):1551.
PMID: 29674655 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Srivastava et al. (2018), Inflammatory response of microglia to prions is controlled by sialylation of PrPSc Sci Rep, 8(1):11326.
PMID: 30054538 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMGA Broeren et al. (2018), Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation PeerJ, 6(0):e4771.
PMID: 29868252 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBF Westendorp et al. (2018), Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response Cell Mol Gastroenterol Hepatol, 5(1):67-82.e1.
PMID: 29276753 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMA Ferko et al. (2018), Effects of metal ions on caspase-1 activation and interleukin-1? release in murine bone marrow-derived macrophages PLoS ONE, 13(8):e0199936.
PMID: 30138321 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Melagraki et al. (2018), In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-?B Ligand (RANKL) Front Pharmacol, 9(0):800.
PMID: 30090063 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Locatelli et al. (2018), Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model Nat. Neurosci., 21(9):1196-1208.
PMID: 30127427 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJM Ubellacker et al. (2018), Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer Cancer Res., 0(0).
PMID: 30065048 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zur et al. (2018), A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and ?v?3 integrin for osteoporosis therapy PLoS Biol., 16(8):e2002979.
PMID: 30142160 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Yin et al. (2018), Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice Cell Death Dis, 9(7):760.
PMID: 29988034 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC McCarthy et al. (2018), Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis Nat Commun, 9(1):3127.
PMID: 30087322 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Ikebuchi et al. (2018), Coupling of bone resorption and formation by RANKL reverse signalling Nature, 0(0).
PMID: 30185903 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Yi et al. (2018), Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPAR? and M2 polarization Cytokine, 111(0):194-205.
PMID: 30176557 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Su et al. (2018), Bone marrow mesenchymal stem cells tune the differentiation of myeloid-derived suppressor cells in bleomycin-induced lung injury Stem Cell Res Ther, 9(1):253.
PMID: 30257700 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Mobarak et al. (2018), Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico Sci Rep, 8(1):13600.
PMID: 30206272 -
JK Kim et al. (2018), GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections Nat Commun, 9(1):4184.
PMID: 30305619 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Meng et al. (2018), Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation Front Pharmacol, 9(0):1053.
PMID: 30319406 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Xiang et al. (2018), The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans Mol Neurodegener, 13(1):49.
PMID: 30185230 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Rubio-Arai et al. (2018), Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of ?-amyloid J Neuroinflammation, 15(1):247.
PMID: 30170611 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGT Ma et al. (2018), Artemisinin-Daumone Hybrid Inhibits Cancer Cell-Mediated Osteolysis by Targeting Cancer Cells and Osteoclasts Cell. Physiol. Biochem., 49(4):1460-1475.
PMID: 30205376 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Das et al. (2018), Induction of Kr�ppel-like factor 2 reduces K/BxN serum-induced arthritis J. Cell. Mol. Med., 0(0).
PMID: 30506878 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMB Uccellini et al. (2018), ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes Cell Rep, 25(10):2784-2796.e3.
PMID: 30517866 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Subramania et al. (2018), Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival Nat Microbiol, 0(0).
PMID: 30420782 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySJ Bae et al. (2018), Protective effects of a traditional herbal extract from Stellaria dichotoma var. lanceolata against Mycobacterium abscessus infections PLoS ONE, 13(11):e0207696.
PMID: 30452471 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAN Billin et al. (2018), HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury Skelet Muscle, 8(1):35.
PMID: 30424786 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Beneke et al. (2018), An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages Sci Rep, 8(1):16281.
PMID: 30389997 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKM Lee et al. (2018), Inhibition of STAT5A promotes osteogenesis by DLX5 regulation Cell Death Dis, 9(11):1136.
PMID: 30429452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMN Lee et al. (2018), Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression Exp. Mol. Med., 50(11):142.
PMID: 30393382 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2018), Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer Cancer Immunol Res, 0(0).
PMID: 30396909 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Ye et al. (2018), Targeted disruption of adenosine kinase in myeloid monocyte cells increases osteoclastogenesis and bone resorption in mice Int. J. Mol. Med., 0(0).
PMID: 29344645 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySA O'Sullivan et al. (2018), Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia J. Neurochem., 0(0).
PMID: 29377126 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Ito et al. (2018), Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice J Innate Immun, 0(0).
PMID: 29393212 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Yoshida et al. (2018), Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo Genes Cells, 0(0).
PMID: 29542224 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySM Oh et al. (2018), TNF-?-mediated ER stress causes elimination of Mycobacterium fortuitum reservoirs by macrophage apoptosis FASEB J., 0(0):fj201701407R.
PMID: 29481309 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Ishii et al. (2018), OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9 FASEB J., 0(0):fj201701424R.
PMID: 29533736 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Gr?evi? et al. (2018), The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair Front Immunol, 9(0):417.
PMID: 29556234 -
Species: Mouse
Sample Types: Whole Cells
Applications: DifferentiationA Mediero et al. (2018), Adenosine Areceptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis FASEB J., 0(0):fj201700217R.
PMID: 29394106 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Zhang et al. (2018), PGC1? Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation J. Bone Miner. Res., 0(0).
PMID: 29521005 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZK Jia et al. (2018), Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-?B Ligand-Induced Osteoclast Differentiation Front Immunol, 9(0):234.
PMID: 29520264 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Datta et al. (2018), Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner Immunity, 0(0).
PMID: 29548672 -
Species: Mouse
Sample Types: Whole Cells
Applications: DifferentiationA Das et al. (2018), High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages Front Immunol, 9(0):22.
PMID: 29403501 -
Species: Mouse
Sample Types: Whole Tissue
Applications: Cell CultureD Song et al. (2018), Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3 Arch. Biochem. Biophys., 647(0):76-83.
PMID: 29678628 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCEJ Waterborg et al. (2018), Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models Front Immunol, 9(0):742.
PMID: 29706963 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Hara et al. (2018), Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice Circulation, 0(0).
PMID: 29700120 -
Species: Mouse
Sample Types: Whole Cell
Applications: Cell CultureM Zhang et al. (2018), Systemic administration of ?-glucan of 200�kDa modulates melanoma microenvironment and suppresses metastatic cancer Oncoimmunology, 7(2):e1387347.
PMID: 29308312 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Kajiwara et al. (2017), Metformin Mediates Protection against Legionella Pneumonia through Activation of AMPK and Mitochondrial Reactive Oxygen Species J. Immunol., 0(0).
PMID: 29246951 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Yang et al. (2017), Interleukin-13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization Oncotarget, 8(59):99495-99503.
PMID: 29245918 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Pei et al. (2017), The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis Sci Rep, 7(1):5107.
PMID: 28698550 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMJ Strowitzki et al. (2017), Pharmacological HIF-inhibition attenuates postoperative adhesion formation Sci Rep, 7(1):13151.
PMID: 29030625 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDC Nascimento et al. (2017), IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population Nat Commun, 8(0):14919.
PMID: 28374774 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOJ Park et al. (2017), Muramyl Dipeptide, a Shared Structural Motif of Peptidoglycans, Is a Novel Inducer of Bone Formation through Induction of Runx2 J. Bone Miner. Res, 0(0).
PMID: 28337794 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Gao et al. (2017), PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy Sci Rep, 7(0):42846.
PMID: 28211523 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Huang et al. (2017), Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats Stem Cells Int, 2017(0):2896874.
PMID: 28694827 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Hanouna et al. (2017), Specific calpain inhibition protects kidney against inflammaging Sci Rep, 7(1):8016.
PMID: 28808241 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Zhou et al. (2017), Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro Biochem. Biophys. Res. Commun, 0(0).
PMID: 28161640 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Ahn et al. (2017), STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis Cell Rep, 21(13):3873-3884.
PMID: 29281834 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF StrƄlberg et al. (2017), Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors J. Leukoc. Biol, 0(0).
PMID: 28196851 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHJ Koh et al. (2017), Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKC� PLoS Pathog, 13(1):e1006126.
PMID: 28125719 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Zhang et al. (2017), 25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p Biochem. Biophys. Res. Commun, 0(0).
PMID: 28257846 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCM Novince et al. (2017), Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health Sci Rep, 7(1):5747.
PMID: 28720797 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Liu et al. (2017), NF-?B activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection Sci Rep, 7(0):40418.
PMID: 28079153 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHJ Ihn et al. (2017), OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo PLoS ONE, 12(1):e0170159.
PMID: 28085946 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Parviainen et al. (2017), Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons Acta Neuropathol Commun, 5(1):74.
PMID: 29041969 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Eger et al. (2017), Scaling of titanium implants entrains inflammation-induced osteolysis Sci Rep, 7(0):39612.
PMID: 28059080 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayC Carmona-Fo et al. (2017), Metabolic origins of spatial organization in the tumor microenvironment Proc. Natl. Acad. Sci. U.S.A, 0(0).
PMID: 28246332 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Kindstedt et al. (2017), CCL11, a novel mediator of inflammatory bone resorption Sci Rep, 7(1):5334.
PMID: 28706221 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLH He et al. (2017), TRPV1 deletion impaired fracture healing and inhibited osteoclast and osteoblast differentiation Sci Rep, 7(0):42385.
PMID: 28225019 -
KM Schneider et al. (2017), The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages Cytokine, 0(0).
PMID: 28800924 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Colaianni et al. (2017), Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice Sci Rep, 7(1):2811.
PMID: 28588307 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJH Oh et al. (2017), Up-Regulation of RANK Expression via ERK1/2 by Insulin Contributes to the Enhancement of Osteoclast Differentiation Mol. Cells, 40(5):371-377.
PMID: 28535663 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJW Lee et al. (2017), The HIV co-receptor CCR5 regulates osteoclast function Nat Commun, 8(1):2226.
PMID: 29263385 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEM Grƶssinger et al. (2017), Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis J. Immunol., 0(0).
PMID: 29246953 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYS Kim et al. (2017), PPAR-? Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism J. Immunol, 0(0).
PMID: 28275133 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySB Mkaddem et al. (2017), Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation Nat Commun, 8(1):246.
PMID: 28811476 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Feng et al. (2017), Extracellular MicroRNAs Induce Potent Innate Immune Responses via TLR7/MyD88-Dependent Mechanisms J. Immunol., 0(0).
PMID: 28768728 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayST Chen et al. (2017), CLEC5A is a critical receptor in innate immunity against Listeria infection Nat Commun, 8(1):299.
PMID: 28824166 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Aki et al. (2017), Hypomorphic A20 expression confers susceptibility to psoriasis PLoS ONE, 12(6):e0180481.
PMID: 28658319 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOC Olson et al. (2017), Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents Cell Rep, 19(1):101-113.
PMID: 28380350 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySW Choi et al. (2017), Barley Seedling Extracts Inhibit RANKL-Induced Differentiation, Fusion, and Maturation of Osteoclasts in the Early-to-Late Stages of Osteoclastogenesis Evid Based Complement Alternat Med, 2017(0):6072573.
PMID: 28567098 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Itoh-Nakad et al. (2017), A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors Cell Rep, 18(10):2401-2414.
PMID: 28273455 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySY Kim et al. (2017), ESRRA (estrogen related receptor, alpha) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense Autophagy, 0(0):0.
PMID: 28841353 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Wang et al. (2017), Activity-independent targeting of mTOR to lysosomes in primary osteoclasts Sci Rep, 7(1):3005.
PMID: 28592812 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBA Fensterhei et al. (2017), The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection J. Immunol, 0(0).
PMID: 28275139 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHH Chen et al. (2017), Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury Theranostics, 7(4):814-825.
PMID: 28382156 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Kram et al. (2017), Small leucine rich proteoglycans, a novel link to osteoclastogenesis Sci Rep, 7(1):12627.
PMID: 28974711 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJY Ao et al. (2017), Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma Mol. Cancer Ther., 0(0).
PMID: 28572167 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Kim et al. (2017), Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6 Sci Adv, 3(4):e1602296.
PMID: 28439546 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Yin et al. (2017), MiR-30a attenuates osteoclastogenesis via targeting DC-STAMP-c-Fos-NFATc1 signaling Am J Transl Res, 9(12):5743-5753.
PMID: 29312525 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMcCarthy R et al. (2016), Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. J Neuroinflammation, 13(1):21.
PMID: 26819091 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHernandez A et al. (2016), The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. J Leukoc Biol, 100(6):1311-1322.
PMID: 27354411 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Fu et al. (2016), Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease J Clin Invest, 0(0).
PMID: 27043283 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Negative regulation of bacterial killing and inflammation by two novel CD16 ligands Eur J Immunol, 0(0).
PMID: 27226142 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayErivan S Ramos-Juni (2016), Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice J. Bone Miner. Res, 0(0).
PMID: 28029186 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status Circ Res, 0(0).
PMID: 27418629 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages Oncotarget, 0(0).
PMID: 27602764 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation Neuropharmacology, 114(0):88-100.
PMID: 27889490 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPesce Viglietti A et al. (2016), Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-kappaB Ligand and Tumor Necrosis Factor Alpha Secretion. Infect Immun, 84(1):11-20.
PMID: 26459511 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYoung-Ran Yoon (2016), Docosahexaenoic acid signaling attenuates the proliferation and differentiation of bone marrow-derived osteoclast precursors and promotes apoptosis in mature osteoclasts Cell. Signal., 29(0):226-232.
PMID: 27836739 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis Eur J Immunol, 0(0).
PMID: 27510283 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection Microbes Infect, 0(0).
PMID: 27637463 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance EMBO Mol Med, 0(0).
PMID: 27402340 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Bossaller et al. (2016), TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus J. Immunol., 197(4):1044-53.
PMID: 27354219 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth Sci Rep, 6(0):37804.
PMID: 27901051 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDechun Geng (2016), Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway Acta Biomater, 0(0).
PMID: 27838465 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySarit Batsir (2016), Dynamics of the sealing zone in cultured osteoclasts Cytoskeleton (Hoboken), 0(0).
PMID: 27997747 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease Int J Mol Sci, 17(8).
PMID: 27529224 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKhor E et al. (2016), Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome. PLoS ONE, 11(1):e0148155.
PMID: 26824232 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4(+) T-cell proliferation Int J Nanomedicine, 11(0):4357-71.
PMID: 27621627 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages Sci Rep, 6(0):32079.
PMID: 27552917 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Treatment with cestode parasite antigens recruits CCR2+ myeloid cells, the adoptive transfer of which ameliorates colitis Infect Immun, 0(0).
PMID: 27672083 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySabrina Ceeraz (2016), VISTA deficiency accelerates the development of fatal murine lupus nephritis Arthritis rheumatology (Hoboken, N.J.), 2016;0(0).
PMID: 27992697 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity Cell, 0(0).
PMID: 27523608 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Ren et al. (2016), Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fc? Receptor (Fc?R) Function J. Biol. Chem, 291(6):3043-52.
PMID: 26627823 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart Eur J Immunol, 0(0).
PMID: 27621211 -
Species: Mouse
Sample Types: Whole Cells
Janko Kos (2016), Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation Neuropharmacology, 114(0):88-100.
PMID: 27889490 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections Sci Rep, 6(0):37211.
PMID: 27845414 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJean-Philippe PradĆØre et al. (2016), Negative regulation of NF-?B p65 activity by serine 536 phosphorylation. Science Signaling, 0(0):1937-9145.
PMID: 27555662 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim K et al. (2015), 15-deoxy-delta12,14-prostaglandin j2 inhibits osteolytic breast cancer bone metastasis and estrogen deficiency-induced bone loss. PLoS ONE, 10(4):e0122764.
PMID: 25859665 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLi B et al. (2015), Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Mol Ther, 23(2):339-51.
PMID: 25327179 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGuo J et al. (2015), Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease. PLoS ONE, 10(11):e0139395.
PMID: 26575486 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYoum Y et al. (2015), The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat Med, 21(3):263-9.
PMID: 25686106 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySophocleous A et al. (2015), Bone Cell-autonomous Contribution of Type 2 Cannabinoid Receptor to Breast Cancer-induced Osteolysis. J Biol Chem, 290(36):22049-60.
PMID: 26195631 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYang C et al. (2015), Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun, 6(0):6115.
PMID: 25655831 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHerbert B et al. (2015), Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations. PLoS ONE, 10(5):e0125387.
PMID: 25946081 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang X et al. (2015), Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice. Endocrinology, 156(4):1408-15.
PMID: 25607894 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGreenblatt M et al. (2015), CHMP5 controls bone turnover rates by dampening NF-kappaB activity in osteoclasts. J Exp Med, 212(8):1283-301.
PMID: 26195726 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWertz I et al. (2015), Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature, 528(7582):370-5.
PMID: 26649818 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOzanne J et al. (2015), The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases. Biochem J, 465(2):271-9.
PMID: 25351958 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXu X et al. (2015), GPCR-mediated PLCbetagamma/PKCbeta/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis. Mol Biol Cell, 26(5):874-86.
PMID: 25568344 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMediero A et al. (2015), Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation. J Bone Miner Res, 30(5):837-54.
PMID: 25483983 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJha A et al. (2015), Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. Immunity, 42(3):419-30.
PMID: 25786174 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim J et al. (2015), MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection. J Immunol, 194(11):5355-65.
PMID: 25917095 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKassem A et al. (2015), Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappaB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts. J Biol Chem, 290(33):20147-58.
PMID: 26085099 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLi et al. (2015), MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest, 125(4):1509-22.
PMID: 25751060 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOberoi R et al. (2015), Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease. PLoS ONE, 10(9):e0137924.
PMID: 26367277 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBehler F et al. (2015), Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice. Infect Immun, 83(1):184-96.
PMID: 25332121 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu K et al. (2015), Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization. Autophagy, 11(2):271-84.
PMID: 25650776 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIhn H et al. (2015), Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway. PLoS ONE, 10(11):e0142201.
PMID: 26536233 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao Z et al. (2015), TNF Induction of NF-kappaB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression. PLoS ONE, 10(8):e0135728.
PMID: 26287732 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang F et al. (2015), Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis. BMC Biotechnol, 15(0):105.
PMID: 26572487 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayUcer S et al. (2015), The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERalpha Signaling in Osteoblasts and Osteoclasts. J Bone Miner Res, 30(7):1138-49.
PMID: 25704845 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMartin I et al. (2015), Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo. J Immunol, 194(8):3924-36.
PMID: 25780044 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFowler T et al. (2015), Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures. J Cell Sci, 128(4):683-94.
PMID: 25609708 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShimizu K et al. (2015), IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages. J Immunol, 194(7):3156-68.
PMID: 25725107 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhang Y et al. (2015), Anabolic bone formation via a site-specific bone-targeting delivery system by interfering with semaphorin 4D expression. J Bone Miner Res, 30(2):286-96.
PMID: 25088728 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNegishi-Koga T et al. (2015), Immune complexes regulate bone metabolism through FcRgamma signalling. Nat Commun, 6(0):6637.
PMID: 25824719 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMatsushita M et al. (2015), A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts. PLoS ONE, 10(1):e0116135.
PMID: 25617756 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMaeda A et al. (2015), WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling. J Biol Chem, 290(22):14004-18.
PMID: 25864198 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAlshbool F et al. (2015), Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis. PLoS ONE, 9(12):e114357.
PMID: 25479235 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAmano et al. (2015), ERK5 Activation Is Essential for Osteoclast Differentiation. PLoS ONE, 10(4):e0125054.
PMID: 25885811 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYu H et al. (2015), FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans. Lipids Health Dis, 14(0):66.
PMID: 26138336 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAntony C et al. (2015), Regulation of L-type Voltage Gated Calcium Channel CACNA1S in Macrophages upon Mycobacterium tuberculosis Infection. PLoS ONE, 10(4):e0124263.
PMID: 25915405 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTan Z et al. (2015), Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism. J Immunol, 194(12):6082-9.
PMID: 25964487 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAbe T et al. (2014), Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8. J Immunol, 193(3):1383-91.
PMID: 24958900 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDavid M et al. (2014), Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. J Biol Chem, 289(10):6551-64.
PMID: 24429286 -
Tang et al. (2014), RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun, 5(0):4657.
PMID: 25118589 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGwyer Findlay et al. (2014), OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis. Proc Natl Acad Sci U S A, 111(6):2289-94.
PMID: 24469824 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTeramachi J et al. (2014), Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone. J Bone Miner Res, 29(6):1456-65.
PMID: 24339057 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKrzeszinski J et al. (2014), miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature, 512(7515):431-5.
PMID: 25043055 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao T et al. (2014), Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions. J Immunol, 193(4):1942-53.
PMID: 25000979 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHayashida C et al. (2014), Osteocytes produce interferon-beta as a negative regulator of osteoclastogenesis. J Biol Chem, 289(16):11545-55.
PMID: 24610813 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAl Faraj et al. (2014), Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI. PLoS ONE, 9(3):e90829.
PMID: 24598763 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFernando M et al. (2014), The pro-inflammatory cytokine, interleukin-6, enhances the polarization of alternatively activated macrophages. PLoS ONE, 9(4):e94188.
PMID: 24736635 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKe K et al. (2014), Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survival. Am J Physiol Endocrinol Metab, 307(1):E61-70.
PMID: 24824657 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayInoue K et al. (2014), Identification of novel transcription factors in osteoclast differentiation using genome-wide analysis of open chromatin determined by DNase-seq. J Bone Miner Res, 29(8):1823-32.
PMID: 24677342 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAn J et al. (2014), Changes of microRNA profile and microRNA-mRNA regulatory network in bones of ovariectomized mice. J Bone Miner Res, 29(3):644-56.
PMID: 23929739 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNacionales D et al. (2014), Aged mice are unable to mount an effective myeloid response to sepsis. J Immunol, 192(2):612-22.
PMID: 24337739 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXie N et al. (2014), miR-27a regulates inflammatory response of macrophages by targeting IL-10. J Immunol, 193(1):327-34.
PMID: 24835395 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGilmour J et al. (2014), A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification. Development, 141(12):2391-401.
PMID: 24850855 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKarpurapu M et al. (2014), Kruppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation. PLoS ONE, 9(4):e93362.
PMID: 24695324 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJeganathan S et al. (2014), Modulation of osteoclastogenesis with macrophage M1- and M2-inducing stimuli. PLoS ONE, 9(8):e104498.
PMID: 25101660 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChaturvedi et al. (2014), Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment. Proc Natl Acad Sci U S A, 111(20):E2120-9.
PMID: 24799675 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWu L et al. (2014), Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy. J Exp Med, 211(7):1449-64.
PMID: 24935258 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKomatsu N et al. (2014), Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med, 20(1):62-8.
PMID: 24362934 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMercken E et al. (2014), SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell, 13(5):787-96.
PMID: 24931715 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGuo H et al. (2014), Lipocalin 2 is a regulator of macrophage polarization and NF-kappaB/STAT3 pathway activation. Mol Endocrinol, 28(10):1616-28.
PMID: 25127375 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXiu Y et al. (2014), Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation. J Clin Invest, 124(1):297-310.
PMID: 24316970 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOhba T et al. (2014), Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL. J Bone Miner Res, 29(6):1431-45.
PMID: 24443409 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao C et al. (2014), Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1. J Immunol, 193(2):879-88.
PMID: 24920846 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJego G et al. (2014), Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes. Leukemia, 28(8):1676-86.
PMID: 24504023 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHsu W et al. (2014), C5L2 is required for C5a-triggered receptor internalization and ERK signaling. Cell Signal, 26(7):1409-19.
PMID: 24631530 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhang J et al. (2014), An unexpected twist to the activation of IKKbeta: TAK1 primes IKKbeta for activation by autophosphorylation. Biochem J, 461(3):531-7.
PMID: 24911653 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBartell et al. (2014), FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun, 5(0):3773.
PMID: 24781012 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySharma et al. (2014), Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts. PLoS ONE, 9(4):e93696.
PMID: 24691516 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPurdue et al. (2014), Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate. Sci Rep, 4(0):7595.
PMID: 25534583 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNoubade et al. (2014), NRROS negatively regulates reactive oxygen species during host defence and autoimmunity. Nature, 509(7499):235-9.
PMID: 24739962 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYao C et al. (2014), The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis. J Biol Chem, 289(10):6775-90.
PMID: 24394418 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYang E et al. (2014), EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1alpha with Th17/Treg control. PLoS ONE, 9(2):e86062.
PMID: 24558360 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHamada et al. (2014), MafB promotes atherosclerosis by inhibiting foam-cell apoptosis. Nat Commun, 5(0):3147.
PMID: 24445679 -
Ohm I et al. (2014), Toll-like receptor 9 mediated responses in cardiac fibroblasts. PLoS ONE, 9(8):e104398.
PMID: 25126740 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBiosse Duplan et al. (2014), Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src. Mol Cell Biol, 34(1):16-29.
PMID: 24144981 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYeon J et al. (2014), Anti-osteoclastogenic activity of praeruptorin A via inhibition of p38/Akt-c-Fos-NFATc1 signaling and PLCgamma-independent Ca2+ oscillation. PLoS ONE, 9(2):e88974.
PMID: 24586466 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKang et al. (2014), A macrophage-specific synthetic promoter for therapeutic application of adiponectin. Gene Ther, 21(4):353-62.
PMID: 24500526 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHirose J et al. (2014), Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast. J Exp Med, 211(1):153-63.
PMID: 24367002 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySun Q et al. (2014), TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation. J Bone Miner Res, 29(1):90-102.
PMID: 23794264 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMcMichael B et al. (2014), The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity. PLoS ONE, 9(1):e87402.
PMID: 24466350 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIsaac et al. (2014), DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo. Cell Death Differ, 21(9):1365-76.
PMID: 24948010 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMukherjee et al. (2014), Distinct actions of akt1 on skeletal architecture and function. PLoS ONE, 9(3):e93040.
PMID: 24663486 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWu C et al. (2014), IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b. J Immunol, 193(6):3036-44.
PMID: 25092892 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChang Y et al. (2014), A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction. J Cell Mol Med, 18(7):1344-57.
PMID: 24758719 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTatano Y et al. (2014), Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep, 4(0):4146.
PMID: 24553452 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHunter et al. (2014), Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors. Oncogene, 33(14):1799-808.
PMID: 23644656 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhong et al. (2014), T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance. Diabetes, 63(4):1289-302.
PMID: 24222350 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTiwari et al. (2014), A nonapoptotic role for CASP2/caspase 2: modulation of autophagy. Autophagy, 10(6):1054-70.
PMID: 24879153 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhang H et al. (2014), NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-kappaB. J Clin Invest, 124(7):3200-14.
PMID: 24892805 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStalvey M et al. (2013), Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease. PLoS ONE, 8(11):e80098.
PMID: 24236172 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJacome-Galarza C et al. (2013), Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery. J Bone Miner Res, 28(5):1203-13.
PMID: 23165930 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKe K et al. (2013), Overexpression of developmentally regulated GTP-binding protein-2 increases bone loss. Am J Physiol Endocrinol Metab, 304(7):E703-10.
PMID: 23360825 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXia W et al. (2013), Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling. J Cell Biol, 200(6):821-37.
PMID: 23509071 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXia W et al. (2013), Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine. J Bone Miner Res, 28(10):2122-35.
PMID: 23649480 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayElcombe S et al. (2013), Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers. PLoS ONE, 8(3):e60086.
PMID: 23533666 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBostrom E et al. (2013), The newly discovered cytokine IL-34 is expressed in gingival fibroblasts, shows enhanced expression by pro-inflammatory cytokines, and stimulates osteoclast differentiation. PLoS ONE, 8(12):e81665.
PMID: 24339952 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim H et al. (2013), Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-kappaB activity and c-Fos induction and prevents inflammatory bone loss in mice. J Leukoc Biol, 94(1):99-107.
PMID: 23657115 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMuruganandan S et al. (2013), Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis. Stem Cells, 31(10):2172-82.
PMID: 23766088 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShah P et al. (2013), Toll-like receptor 2 ligands regulate monocyte Fcgamma receptor expression and function. J Biol Chem, 288(17):12345-52.
PMID: 23504312 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYang Z et al. (2013), Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity. , 0(0).
PMID: 23536877 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYamamizu K et al. (2013), Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports, 1(6):545-59.
PMID: 24371809 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim J et al. (2013), Differential immune responses to Segniliparus rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles. PLoS ONE, 8(3):e59646.
PMID: 23555735 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBraun T et al. (2013), Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover. J Bone Miner Res, 28(4):936-47.
PMID: 23169443 -
Zou W et al. (2013), Talin1 and Rap1 are critical for osteoclast function. Mol Cell Biol, 33(4):830-44.
PMID: 23230271 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySandig H et al. (2013), IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation. Eur J Immunol, 43(4):979-88.
PMID: 23404570 -
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPau E et al. (2013), Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13. Genes Immun, 14(3):154-61.
PMID: 23328841 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayUchiyama R et al. (2013), Fas-mediated inflammatory response in Listeria monocytogenes infection. J Immunol, 190(8):4245-54.
PMID: 23509366 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMa et al. (2013), RNA interference-mediated silencing of Atp6i prevents both periapical bone erosion and inflammation in the mouse model of endodontic disease. Infect Immun, 81(4):1021-30.
PMID: 23166162 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChoi J et al. (2013), Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway. Cell Signal, 25(5):1222-7.
PMID: 23434822 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureLee S et al. (2013), Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production. PLoS ONE, 8(12):e80873.
PMID: 24324641 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureSong K et al. (2013), Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Cancer Res, 73(24):7254-64.
PMID: 24158094 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 109(25):9971-6.
PMID: 22665806 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhao E et al. (2012), Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer. Oncoimmunology, 1(2):152-161.
PMID: 22720236 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHayashi M et al. (2012), Osteoprotection by semaphorin 3A. Nature, 485(7396):69-74.
PMID: 22522930 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBarin JG et al. (2012), Macrophages participate in IL-17-mediated inflammation. Eur. J. Immunol., 42(3):726-36.
PMID: 22161142 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHassan F et al. (2012), Role of c-Jun N-terminal protein kinase 1/2 (JNK1/2) in macrophage-mediated MMP-9 production in response to Moraxella catarrhalis lipooligosaccharide (LOS). PLoS ONE, 7(5):e37912.
PMID: 22655080 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFujiwara T et al. (2011), Macrophage infiltration predicts a poor prognosis for human ewing sarcoma. Am. J. Pathol., 179(3):1157-70.
PMID: 21771572 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCook BD et al. (2011), Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood, 117(24):6489-97.
PMID: 21515822 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJang HD et al. (2011), Inactivation of glycogen synthase kinase-3beta is required for osteoclast differentiation. J. Biol. Chem., 286(45):39043-50.
PMID: 21949120 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayScapini P et al. (2010), Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. J. Exp. Med., 207(8):1757-73.
PMID: 20624892 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhang G et al. (2010), B7-h3 augments the inflammatory response and is associated with human sepsis. J. Immunol., 185(6):3677-84.
PMID: 20696859 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKulkarni RN et al. (2010), Inhibition of osteoclastogenesis by mechanically loaded osteocytes: involvement of MEPE. Calcif. Tissue Int., 87(5):461-8.
PMID: 20725825 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShanmugarajan S et al. (2010), Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation. Endocrinology, 151(9):4389-99.
PMID: 20610564 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang L et al. (2009), Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone, 45(2):309-20.
PMID: 19379851 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBinder NB et al. (2009), Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. Nat. Med., 15(4):417-24.
PMID: 19330010 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKiuru M et al. (2009), Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone. J. Bone Miner. Res., 24(9):1598-607.
PMID: 19338448 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWalker EC et al. (2008), Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling. J. Bone Miner. Res., 23(12):2025-32.
PMID: 18665789 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKrum SA et al. (2008), Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J., 27(3):535-45.
PMID: 18219273 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJinushi M et al. (2008), Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res., 68(21):8889-98.
PMID: 18974133 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKovacic N et al. (2007), The Fas/Fas ligand system inhibits differentiation of murine osteoblasts but has a limited role in osteoblast and osteoclast apoptosis. J. Immunol., 178(6):3379-89.
PMID: 17339432 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJohansson MK et al. (2007), Hematopoietic stem cell-targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice. Blood, 109(12):5178-85.
PMID: 17332244 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNiki Y et al. (2007), Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J. Immunol., 179(1):639-46.
PMID: 17579086 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayNakanishi M et al. (2007), Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells. Eur. J. Neurosci., 25(3):649-58.
PMID: 17328769 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayO'Sullivan S et al. (2007), Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms. J. Bone Miner. Res., 22(11):1679-89.
PMID: 17663639 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIslam S et al. (2007), Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells. Biochem. Biophys. Res. Commun., 360(2):346-51.
PMID: 17597583 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJia D et al. (2006), Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinology, 147(12):5592-9.
PMID: 16935844 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMohamedali KA et al. (2006), Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel. Cancer Res., 66(22):10919-28.
PMID: 17108129 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim SY et al. (2006), Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions. J. Biol. Chem., 281(39):28794-801.
PMID: 16891306 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassayde Vries TJ et al. (2006), Gingival fibroblasts are better at inhibiting osteoclast formation than periodontal ligament fibroblasts. J. Cell. Biochem., 98(2):370-82.
PMID: 16440316 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPonomarev ED et al. (2005), Development of a culture system that supports adult microglial cell proliferation and maintenance in the resting state. J. Immunol. Methods, 300(1):32-46.
PMID: 15893321 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGevrey JC et al. (2005), Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine). J. Immunol., 175(6):3737-45.
PMID: 16148119 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoConway JG et al. (2005), Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. Proc. Natl. Acad. Sci. U.S.A., 102(44):16078-83.
PMID: 16249345 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySharif MN et al. (2004), IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. J. Immunol., 172(10):6476-81.
PMID: 15128840 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMiller YI et al. (2002), Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. J. Biol. Chem., 278(3):1561-8.
PMID: 12424240 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySubramanian K et al. (0), Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nat Microbio0(0).
PMID: 30420782
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